Compile Data Set for Download or QSAR

Found 103 hits of ec50 for UniProtKB: P23944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50230393 (CHEMBL553231) Show SMILES Cl.CC(C1=NCCN1)c1cccc2ccccc12 |t:2| Show InChI InChI=1S/C15H16N2.ClH/c1-11(15-16-9-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13;/h2-8,11H,9-10H2,1H3,(H,16,17);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.000540	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50230392 (CHEMBL554581) Show SMILES Cl.CC(c1ncc[nH]1)c1cccc2ccccc12 Show InChI InChI=1S/C15H14N2.ClH/c1-11(15-16-9-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13;/h2-11H,1H3,(H,16,17);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.00770	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156310 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)phen...) Show SMILES Oc1ccc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O6S/c20-14-10-8-13(9-11-14)5-4-12-24-16-17(19(21)25-18-16)26(22,23)15-6-2-1-3-7-15/h1-3,6-11,20H,4-5,12H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50029051 ((-)-arterenol | (-)-noradrenaline | (-)-norepineph...) Show SMILES NC[C@H](O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156304 (3-benzenesulfonyl-4-ethoxy-furazan 2-oxide | 4-eth...) Show SMILES CCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C10H10N2O5S/c1-2-16-9-10(12(13)17-11-9)18(14,15)8-6-4-3-5-7-8/h3-7H,2H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001922 (2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...) Show SMILES C(C1=NCCN1)c1cccc2ccccc12 |t:1| Show InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186605 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) Show SMILES COc1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(OC)c1O Show InChI InChI=1S/C19H20N2O8S/c1-26-15-11-13(12-16(27-2)17(15)22)7-6-10-28-18-19(21(23)29-20-18)30(24,25)14-8-4-3-5-9-14/h3-5,8-9,11-12,22H,6-7,10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156303 (2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8...) Show SMILES Cc1c(C)c2OC(C)(COc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)CCc2c(C)c1O Show InChI InChI=1S/C22H24N2O7S/c1-13-14(2)19-17(15(3)18(13)25)10-11-22(4,30-19)12-29-20-21(24(26)31-23-20)32(27,28)16-8-6-5-7-9-16/h5-9,25H,10-12H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50027031 ((2-Chloro-phenyl)-(4,5-dihydro-1H-imidazol-2-ylmet...) Show SMILES Clc1ccccc1NCC1=NCCN1 |t:10| Show InChI InChI=1S/C10H12ClN3/c11-8-3-1-2-4-9(8)14-7-10-12-5-6-13-10/h1-4,14H,5-7H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity against alpha-1 adrenergic receptor from rat vas deferens				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50027035 (3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...) Show SMILES Oc1cccc(NCC2=NCCN2)c1 |t:8| Show InChI InChI=1S/C10H13N3O/c14-9-3-1-2-8(6-9)13-7-10-11-4-5-12-10/h1-3,6,13-14H,4-5,7H2,(H,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligand				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156308 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) Show SMILES CC(C)(C)c1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(c1O)C(C)(C)C Show InChI InChI=1S/C25H32N2O6S/c1-24(2,3)19-15-17(16-20(21(19)28)25(4,5)6)11-10-14-32-22-23(27(29)33-26-22)34(30,31)18-12-8-7-9-13-18/h7-9,12-13,15-16,28H,10-11,14H2,1-6H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186606 (3-(4-hydroxyphenyl)prop-1,2-diyl dinitrate | CHEMB...) Show SMILES Oc1ccc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc1 Show InChI InChI=1S/C9H10N2O6/c12-9-3-1-7(2-4-9)5-8(10(13)14)6-17-11(15)16/h1-4,8,12H,5-6H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50036910 (4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole | CHEMBL3...) Show SMILES CC(c1cnc[nH]1)c1cccc2ccccc12 Show InChI InChI=1S/C15H14N2/c1-11(15-9-16-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13/h2-11H,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	153	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description 50% Molar effective concentration for agonistic activity against Alpha-1 adrenergic receptor in rat aorta				J Med Chem 39: 3001-13 (1996) Article DOI: 10.1021/jm9506074 BindingDB Entry DOI: 10.7270/Q2BV7KBH
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50067212 (CHEBI:8093 | Cyclomydril | Duo-Medihaler | Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 |r| Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	155	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50230389 (CHEMBL541105) Show SMILES Cl.CC(c1c[nH]cn1)c1cccc2ccccc12 Show InChI InChI=1S/C15H14N2.ClH/c1-11(15-9-16-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13;/h2-11H,1H3,(H,16,17);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50230388 (CHEMBL537830) Show SMILES Cl.C(c1ncc[nH]1)c1cccc2ccccc12 Show InChI InChI=1S/C14H12N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-9H,10H2,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186612 (1,2-bis-nitrooxy-propane | CHEMBL206527) Show SMILES CC(CO[N+]([O-])=O)O[N+]([O-])=O Show InChI InChI=1S/C3H6N2O6/c1-3(11-5(8)9)2-10-4(6)7/h3H,2H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50036913 ((+-)-4-(alpha,2,3-trimethylbenzyl)imidazole | 4-[1...) Show SMILES CC(c1cnc[nH]1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	281	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description 50% Molar effective concentration afainst Alpha-1 adrenergic receptor in rat aorta				J Med Chem 39: 3001-13 (1996) Article DOI: 10.1021/jm9506074 BindingDB Entry DOI: 10.7270/Q2BV7KBH
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50027036 ((4,5-Dihydro-1H-imidazol-2-ylmethyl)-methyl-p-toly...) Show SMILES CN(CC1=NCCN1)c1ccc(C)cc1 |t:3| Show InChI InChI=1S/C12H17N3/c1-10-3-5-11(6-4-10)15(2)9-12-13-7-8-14-12/h3-6H,7-9H2,1-2H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligand				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50230390 (CHEBI:48556 | MEDETOMIDINE HYDROCHLORIDE | MPV-785...) Show SMILES Cl.CC(c1c[nH]cn1)c1cccc(C)c1C Show InChI InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50027032 ((4,5-Dihydro-1H-imidazol-2-ylmethyl)-p-tolyl-amine...) Show SMILES Cc1ccc(NCC2=NCCN2)cc1 |t:7| Show InChI InChI=1S/C11H15N3/c1-9-2-4-10(5-3-9)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity against alpha-1 adrenergic receptor from rat vas deferens				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156310 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)phen...) Show SMILES Oc1ccc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O6S/c20-14-10-8-13(9-11-14)5-4-12-24-16-17(19(21)25-18-16)26(22,23)15-6-2-1-3-7-15/h1-3,6-11,20H,4-5,12H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186604 (4-((N-(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl...) Show SMILES CN(CCCc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)Cc1no[n+]([O-])c1C(N)=O Show InChI InChI=1S/C22H34N4O4/c1-21(2,3)15-11-14(12-16(19(15)27)22(4,5)6)9-8-10-25(7)13-17-18(20(23)28)26(29)30-24-17/h11-12,27H,8-10,13H2,1-7H3,(H2,23,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131411 (4-(4-Chloro-benzyl)-2-methyl-2H-phthalazin-1-one |...) Show SMILES Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O Show InChI InChI=1S/C16H13ClN2O/c1-19-16(20)14-5-3-2-4-13(14)15(18-19)10-11-6-8-12(17)9-7-11/h2-9H,10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186605 (4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...) Show SMILES COc1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(OC)c1O Show InChI InChI=1S/C19H20N2O8S/c1-26-15-11-13(12-16(27-2)17(15)22)7-6-10-28-18-19(21(23)29-20-18)30(24,25)14-8-4-3-5-9-14/h3-5,8-9,11-12,22H,6-7,10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186608 (3-((4-hydroxy-3,5-dimethoxy)phenyl)prop-1,2-diyl d...) Show SMILES COc1cc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc(OC)c1O Show InChI InChI=1S/C11H14N2O8/c1-19-9-4-7(5-10(20-2)11(9)14)3-8(12(15)16)6-21-13(17)18/h4-5,8,14H,3,6H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156303 (2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8...) Show SMILES Cc1c(C)c2OC(C)(COc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)CCc2c(C)c1O Show InChI InChI=1S/C22H24N2O7S/c1-13-14(2)19-17(15(3)18(13)25)10-11-22(4,30-19)12-29-20-21(24(26)31-23-20)32(27,28)16-8-6-5-7-9-16/h5-9,25H,10-12H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM56339 (4-(4-chlorobenzyl)-1(2H)-phthalazinone | 4-(4-chlo...) Show SMILES Clc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1 Show InChI InChI=1S/C15H11ClN2O/c16-11-7-5-10(6-8-11)9-14-12-3-1-2-4-13(12)15(19)18-17-14/h1-8H,9H2,(H,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131402 (4-(benzo[d][1,3]dioxol-5-ylmethyl)-2-methylphthala...) Show SMILES Cn1nc(Cc2ccc3OCOc3c2)c2ccccc2c1=O Show InChI InChI=1S/C17H14N2O3/c1-19-17(20)13-5-3-2-4-12(13)14(18-19)8-11-6-7-15-16(9-11)22-10-21-15/h2-7,9H,8,10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183669 (4-(4-(methylthio)benzyl)-2-methylphthalazin-1(2H)-...) Show SMILES CSc1ccc(Cc2nn(C)c(=O)c3ccccc23)cc1 Show InChI InChI=1S/C17H16N2OS/c1-19-17(20)15-6-4-3-5-14(15)16(18-19)11-12-7-9-13(21-2)10-8-12/h3-10H,11H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM31046 (3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...) Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10| Show InChI InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity against alpha-1 adrenergic receptor from rat vas deferens				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156307 (3-(4-hydroxyphenyl)propyl nitrate | 4-(3-Nitrooxy-...) Show SMILES Oc1ccc(CCCO[N+]([O-])=O)cc1 Show InChI InChI=1S/C9H11NO4/c11-9-5-3-8(4-6-9)2-1-7-14-10(12)13/h3-6,11H,1-2,7H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50470944 (CHEMBL336161) Show SMILES [H][C@]1(CCCc2c(NS(C)(=O)=O)c(O)ccc12)C1=NCCN1 |t:19| Show InChI InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)/t11-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50156305 (2,5,7,8-Tetramethyl-2-(3-nitrooxy-propoxymethyl)-c...) Show SMILES Cc1c(C)c2OC(C)(COCCCO[N+]([O-])=O)CCc2c(C)c1O Show InChI InChI=1S/C17H25NO6/c1-11-12(2)16-14(13(3)15(11)19)6-7-17(4,24-16)10-22-8-5-9-23-18(20)21/h19H,5-10H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183666 (4-(2,4-dichlorobenzyl)-2-methylphthalazin-1(2H)-on...) Show SMILES Cn1nc(Cc2ccc(Cl)cc2Cl)c2ccccc2c1=O Show InChI InChI=1S/C16H12Cl2N2O/c1-20-16(21)13-5-3-2-4-12(13)15(19-20)8-10-6-7-11(17)9-14(10)18/h2-7,9H,8H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183687 (4-(4-chlorobenzyl)-2-ethylphthalazin-1(2H)-one | C...) Show SMILES CCn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O Show InChI InChI=1S/C17H15ClN2O/c1-2-20-17(21)15-6-4-3-5-14(15)16(19-20)11-12-7-9-13(18)10-8-12/h3-10H,2,11H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183690 (4-(2-chlorobenzyl)-2-methylphthalazin-1(2H)-one | ...) Show SMILES Cn1nc(Cc2ccccc2Cl)c2ccccc2c1=O Show InChI InChI=1S/C16H13ClN2O/c1-19-16(20)13-8-4-3-7-12(13)15(18-19)10-11-6-2-5-9-14(11)17/h2-9H,10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50186603 (4-((N-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)...) Show SMILES CN(Cc1no[n+]([O-])c1C(N)=O)CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1 Show InChI InChI=1S/C19H26N4O5/c1-10-11(2)17-13(12(3)16(10)24)6-7-19(4,27-17)9-22(5)8-14-15(18(20)25)23(26)28-21-14/h24H,6-9H2,1-5H3,(H2,20,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Università degli Studi di Torino Curated by ChEMBL					Assay Description Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips				J Med Chem 49: 2886-97 (2006) Article DOI: 10.1021/jm0510530 BindingDB Entry DOI: 10.7270/Q2ZC82G7
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50027037 ((4,5-Dihydro-1H-imidazol-2-ylmethyl)-ethyl-p-tolyl...) Show SMILES CCN(CC1=NCCN1)c1ccc(C)cc1 |t:4| Show InChI InChI=1S/C13H19N3/c1-3-16(10-13-14-8-9-15-13)12-6-4-11(2)5-7-12/h4-7H,3,8-10H2,1-2H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity against alpha-1 adrenergic receptor from rat vas deferens				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50118702 (2-Amino-1-(2,5-dimethoxy-phenyl)-ethanol | CHEMBL1...) Show SMILES COc1ccc(OC)c(c1)C(O)CN Show InChI InChI=1S/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at alpha1D adrenoreceptor in Rattus norvegicus (rat) aorta				Citation and Details Article DOI: 10.1007/s00044-004-0020-z BindingDB Entry DOI: 10.7270/Q2PZ5CQB
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50118702 (2-Amino-1-(2,5-dimethoxy-phenyl)-ethanol | CHEMBL1...) Show SMILES COc1ccc(OC)c(c1)C(O)CN Show InChI InChI=1S/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effective concentration of the compound was determined in vitro against rat aorta Alpha-1D adrenergic receptor;* indicates EC50 < 15% at a concentrat...				J Med Chem 45: 4395-7 (2002) BindingDB Entry DOI: 10.7270/Q20001FV
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183678 (4-(2-chlorobenzyl)phthalazin-1(2H)-one | CHEMBL378...) Show SMILES Clc1ccccc1Cc1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C15H11ClN2O/c16-13-8-4-1-5-10(13)9-14-11-6-2-3-7-12(11)15(19)18-17-14/h1-8H,9H2,(H,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131408 (4-(3,4-Dimethoxy-benzyl)-2-methyl-2H-phthalazin-1-...) Show SMILES COc1ccc(Cc2nn(C)c(=O)c3ccccc23)cc1OC Show InChI InChI=1S/C18H18N2O3/c1-20-18(21)14-7-5-4-6-13(14)15(19-20)10-12-8-9-16(22-2)17(11-12)23-3/h4-9,11H,10H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) Show SMILES CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1 |t:18| Show InChI InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) Show SMILES CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1 |t:18| Show InChI InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article	n/a	n/a	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at alpha1D adrenoreceptor in Rattus norvegicus (rat) aorta				Citation and Details Article DOI: 10.1007/s00044-004-0020-z BindingDB Entry DOI: 10.7270/Q2PZ5CQB
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50118703 (CHEMBL109783 | N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) Show SMILES CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)C1=NCCN1 |t:18| Show InChI InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Effective concentration of the compound was determined in vitro against rat aorta Alpha-1D adrenergic receptor;* indicates EC50 < 15% at a concentrat...				J Med Chem 45: 4395-7 (2002) BindingDB Entry DOI: 10.7270/Q20001FV
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183665 (4-(4-chlorobenzyl)-2-allylphthalazin-1(2H)-one | C...) Show SMILES Clc1ccc(Cc2nn(CC=C)c(=O)c3ccccc23)cc1 Show InChI InChI=1S/C18H15ClN2O/c1-2-11-21-18(22)16-6-4-3-5-15(16)17(20-21)12-13-7-9-14(19)10-8-13/h2-10H,1,11-12H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131414 (4-(benzo[d][1,3]dioxol-5-ylmethyl)phthalazin-1(2H)...) Show SMILES O=c1[nH]nc(Cc2ccc3OCOc3c2)c2ccccc12 Show InChI InChI=1S/C16H12N2O3/c19-16-12-4-2-1-3-11(12)13(17-18-16)7-10-5-6-14-15(8-10)21-9-20-14/h1-6,8H,7,9H2,(H,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)	BDBM50019061 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...) Show SMILES NCC(O)c1cc(O)c(O)cc1F Show InChI InChI=1S/C8H10FNO3/c9-5-2-7(12)6(11)1-4(5)8(13)3-10/h1-2,8,11-13H,3,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane				J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)-RA...)	BDBM35234 (DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...) Show SMILES NCC(O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane				J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 103 total )  |  Next  |  Last  >>

Jump to: