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Compile Data Set for Download or QSAR

Found 3 hits of ec50 for UniProtKB: P51160   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'


(Homo sapiens (Human))
BDBM50560848
PNG
(4-Methoxyevodiamine | CHEMBL2171791)
Show SMILES COc1cccc2N(C)C3N(CCc4c3[nH]c3ccccc43)C(=O)c12
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a


TBA

Assay Description
Inhibition of human PDE6C (2-854 residues) expressed in Sf9 cells incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00983
BindingDB Entry DOI: 10.7270/Q2668HWF
More data for this
Ligand-Target Pair
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'


(Homo sapiens (Human))
BDBM50016250
PNG
(CHEMBL81925)
Show SMILES CN1C2N(CCc3c2[nH]c2ccccc32)C(=O)c2ccccc12
Show InChI InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3
UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a


TBA

Assay Description
Inhibition of human PDE6C (2-854 residues) expressed in Sf9 cells incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00983
BindingDB Entry DOI: 10.7270/Q2668HWF
More data for this
Ligand-Target Pair
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'


(Homo sapiens (Human))
BDBM50560849
PNG
(CHEMBL4782533)
Show SMILES [H][C@]12N(C)c3cccc(OC)c3C(=O)N1CCc1c2[nH]c2ccccc12 |r|
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a


TBA

Assay Description
Inhibition of human PDE6C (2-854 residues) expressed in Sf9 cells incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00983
BindingDB Entry DOI: 10.7270/Q2668HWF
More data for this
Ligand-Target Pair