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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: P16473   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thyrotropin receptor


(Homo sapiens (Human))		BDBM50189778
PNG
(CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...)
Show SMILES COc1cccc(c1)-c1nc(SC)nc2sc(C(=O)NC(C)(C)C)c(N)c12
Show InChI InChI=1S/C19H22N4O2S2/c1-19(2,3)23-16(24)15-13(20)12-14(10-7-6-8-11(9-10)25-4)21-18(26-5)22-17(12)27-15/h6-9H,20H2,1-5H3,(H,23,24)
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Article
PubMed
n/an/an/an/a 6.50E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at TSHR expressed in HEK293 EM cells measured by intracellular cAMP accumulation

J Med Chem 49: 3888-96 (2006)


Article DOI: 10.1021/jm060247s
BindingDB Entry DOI: 10.7270/Q29886MR
More data for this
Ligand-Target Pair