BindingDB PrimarySearch

Found 9 hits of ic50 for UniProtKB: P11678
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Eosinophil peroxidase (Human)	BDBM50106515 (7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...) Show SMILES Nc1nc(OCc2ccccc2)c2[nH]nnc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human EPX bromination activity assessed as reduction in H2O2 catalyzed 3-bromo tyrosine formation from tyrosine and potassium bromide p...				ACS Med Chem Lett 9: 1175-1180 (2018) Article DOI: 10.1021/acsmedchemlett.8b00308 BindingDB Entry DOI: 10.7270/Q2W0997Z
					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM50507390 (CHEMBL4482878 \| US10981879, Example 3) Show SMILES Nc1cc(SCc2ccccc2F)c2nn[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human EPX bromination activity assessed as reduction in H2O2 catalyzed 3-bromo tyrosine formation from tyrosine and potassium bromide p...				ACS Med Chem Lett 9: 1175-1180 (2018) Article DOI: 10.1021/acsmedchemlett.8b00308 BindingDB Entry DOI: 10.7270/Q2W0997Z
					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM357629 (7-benzyl-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine ...) Show SMILES Nc1cc(Cc2ccccc2)c2nn[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 mins				Citation and Details Article DOI: 10.1016/j.bmc.2020.115723 BindingDB Entry DOI: 10.7270/Q21Z4829
TBA					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM434842 (7-{18-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.113,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...				US Patent US10577383 (2020) BindingDB Entry DOI: 10.7270/Q2474D8B
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM434844 (7-{14′-Oxa-3′,4′,10′-triaz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...				US Patent US10577383 (2020) BindingDB Entry DOI: 10.7270/Q2474D8B
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM50554034 (CHEMBL4747269) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 mins				Citation and Details Article DOI: 10.1016/j.bmc.2020.115723 BindingDB Entry DOI: 10.7270/Q21Z4829
TBA					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM434841 (7-{18-oxa-3,4,10-triazatetracyclo[17.3.1.13,6.112,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...				US Patent US10577383 (2020) BindingDB Entry DOI: 10.7270/Q2474D8B
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM434843 (7-{3-Oxa-10,11,17-triazatetracyclo[16.2.2.14,8.110...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description EPX bromination activity was measured in 100 mM KPi (pH 7.4) by monitoring the H2O2 catalyzed formation of 3-bromo tyrosine from tyrosine and potassi...				US Patent US10577383 (2020) BindingDB Entry DOI: 10.7270/Q2474D8B
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Eosinophil peroxidase (Human)	BDBM50554035 (CHEMBL4790231) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human EPX bromination activity using tyrosine as substrate by measuring 3-bromo tyrosine formation incubated for 10 mins				Citation and Details Article DOI: 10.1016/j.bmc.2020.115723 BindingDB Entry DOI: 10.7270/Q21Z4829
TBA					More data for this Ligand-Target Pair