Compile Data Set for Download or QSAR

Found 16 hits of ic50 for UniProtKB: P22607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436191 (US10590109, Compound 9) Show SMILES COCCNc1cc(NC(=O)N(C)c2ccc(CN3CCOCC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C22H25N7O5/c1-28(22(32)27-19-9-17(24-5-7-33-2)16(10-23)11-25-19)20-4-3-15(18(13-30)26-20)12-29-6-8-34-14-21(29)31/h3-4,9,11,13H,5-8,12,14H2,1-2H3,(H2,24,25,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436208 (US10590109, Compound 26) Show SMILES C[C@@H](CO)Oc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N |r| Show InChI InChI=1S/C23H27N7O5/c1-15(13-31)35-19-8-20(25-10-17(19)9-24)27-23(34)29(3)21-5-4-16(18(14-32)26-21)11-30-7-6-28(2)12-22(30)33/h4-5,8,10,14-15,31H,6-7,11-13H2,1-3H3,(H,25,27,34)/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436193 (US10590109, Compound 11) Show SMILES CN(C(=O)Nc1cc(Cl)c(cn1)C#N)c1ccc(CN2CCOCC2=O)c(C=O)n1 Show InChI InChI=1S/C19H17ClN6O4/c1-25(19(29)24-16-6-14(20)13(7-21)8-22-16)17-3-2-12(15(10-27)23-17)9-26-4-5-30-11-18(26)28/h2-3,6,8,10H,4-5,9,11H2,1H3,(H,22,24,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436194 (US10590109, Compound 12) Show SMILES COCCOc1cc(NC(=O)N(C)c2ccc(CN3CCOCC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C22H24N6O6/c1-27(22(31)26-19-9-18(34-8-7-32-2)16(10-23)11-24-19)20-4-3-15(17(13-29)25-20)12-28-5-6-33-14-21(28)30/h3-4,9,11,13H,5-8,12,14H2,1-2H3,(H,24,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436195 (US10590109, Compound 13) Show SMILES CC(C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCOCC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C22H24N6O5/c1-14(2)33-18-8-19(24-10-16(18)9-23)26-22(31)27(3)20-5-4-15(17(12-29)25-20)11-28-6-7-32-13-21(28)30/h4-5,8,10,12,14H,6-7,11,13H2,1-3H3,(H,24,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436196 (US10590109, Compound 14) Show SMILES COC[C@@H](C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCOCC3=O)c(C=O)n2)ncc1C#N |r| Show InChI InChI=1S/C23H26N6O6/c1-15(13-33-3)35-19-8-20(25-10-17(19)9-24)27-23(32)28(2)21-5-4-16(18(12-30)26-21)11-29-6-7-34-14-22(29)31/h4-5,8,10,12,15H,6-7,11,13-14H2,1-3H3,(H,25,27,32)/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436198 (US10590109, Compound 16) Show SMILES CC(C)Nc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C23H28N8O3/c1-15(2)26-18-9-20(25-11-17(18)10-24)28-23(34)30(4)21-6-5-16(19(14-32)27-21)12-31-8-7-29(3)13-22(31)33/h5-6,9,11,14-15H,7-8,12-13H2,1-4H3,(H2,25,26,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436199 (US10590109, Compound 17) Show SMILES CN(C(=O)Nc1cc(Cl)c(cn1)C#N)c1ccc(CN2CCN(C)CC2=O)c(C=O)n1 Show InChI InChI=1S/C20H20ClN7O3/c1-26-5-6-28(19(30)11-26)10-13-3-4-18(24-16(13)12-29)27(2)20(31)25-17-7-15(21)14(8-22)9-23-17/h3-4,7,9,12H,5-6,10-11H2,1-2H3,(H,23,25,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436200 (US10590109, Compound 18 | US10590109, Compound 25) Show SMILES COC[C@@H](C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N |r| Show InChI InChI=1S/C24H29N7O5/c1-16(15-35-4)36-20-9-21(26-11-18(20)10-25)28-24(34)30(3)22-6-5-17(19(14-32)27-22)12-31-8-7-29(2)13-23(31)33/h5-6,9,11,14,16H,7-8,12-13,15H2,1-4H3,(H,26,28,34)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436201 (US10590109, Compound 19) Show SMILES CC(C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C23H27N7O4/c1-15(2)34-19-9-20(25-11-17(19)10-24)27-23(33)29(4)21-6-5-16(18(14-31)26-21)12-30-8-7-28(3)13-22(30)32/h5-6,9,11,14-15H,7-8,12-13H2,1-4H3,(H,25,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436197 (US10590109, Compound 15 | US10590109, Compound 20) Show SMILES COCCNc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C23H28N8O4/c1-29-7-8-31(22(33)14-29)13-16-4-5-21(27-19(16)15-32)30(2)23(34)28-20-10-18(25-6-9-35-3)17(11-24)12-26-20/h4-5,10,12,15H,6-9,13-14H2,1-3H3,(H2,25,26,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436203 (US10590109, Compound 21) Show SMILES COCCNc1cc(NC(=O)N(C)c2ccc(CO)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C18H20N6O4/c1-24(17-4-3-12(10-25)15(11-26)22-17)18(27)23-16-7-14(20-5-6-28-2)13(8-19)9-21-16/h3-4,7,9,11,25H,5-6,10H2,1-2H3,(H2,20,21,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436205 (US10590109, Compound 22) Show SMILES CN(C(=O)Nc1cc(Cl)c(cn1)C#N)c1ccc(CO)c(C=O)n1 Show InChI InChI=1S/C15H12ClN5O3/c1-21(14-3-2-9(7-22)12(8-23)19-14)15(24)20-13-4-11(16)10(5-17)6-18-13/h2-4,6,8,22H,7H2,1H3,(H,18,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436206 (US10590109, Compound 24) Show SMILES COC[C@H](C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N |r| Show InChI InChI=1S/C24H29N7O5/c1-16(15-35-4)36-20-9-21(26-11-18(20)10-25)28-24(34)30(3)22-6-5-17(19(14-32)27-22)12-31-8-7-29(2)13-23(31)33/h5-6,9,11,14,16H,7-8,12-13,15H2,1-4H3,(H,26,28,34)/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436200 (US10590109, Compound 18 | US10590109, Compound 25) Show SMILES COC[C@@H](C)Oc1cc(NC(=O)N(C)c2ccc(CN3CCN(C)CC3=O)c(C=O)n2)ncc1C#N |r| Show InChI InChI=1S/C24H29N7O5/c1-16(15-35-4)36-20-9-21(26-11-18(20)10-25)28-24(34)30(3)22-6-5-17(19(14-32)27-22)12-31-8-7-29(2)13-23(31)33/h5-6,9,11,14,16H,7-8,12-13,15H2,1-4H3,(H,26,28,34)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 [399-806] (Homo sapiens (Human))	BDBM436192 (US10590109, Compound 10) Show SMILES CC(C)Nc1cc(NC(=O)N(C)c2ccc(CN3CCOCC3=O)c(C=O)n2)ncc1C#N Show InChI InChI=1S/C22H25N7O4/c1-14(2)25-17-8-19(24-10-16(17)9-23)27-22(32)28(3)20-5-4-15(18(12-30)26-20)11-29-6-7-33-13-21(29)31/h4-5,8,10,12,14H,6-7,11,13H2,1-3H3,(H2,24,25,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing InnoCare Pharma Tech Co., Ltd. US Patent					Assay Description FGFR3: The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...				US Patent US10590109 (2020) BindingDB Entry DOI: 10.7270/Q2J969D2
					More data for this Ligand-Target Pair