Compile Data Set for Download or QSAR

Found 153 hits of ic50 for UniProtKB: P19490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50458948 (CHEMBL4204422) Show SMILES CCN(CC)c1ccc(cc1)\N=N\c1ccc(cc1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCCCCCCNCCCCNC(=O)[C@@H](N)CCCNC(N)=N |r| Show InChI InChI=1S/C39H64N12O4/c1-3-51(4-2)32-21-19-31(20-22-32)50-49-30-17-15-29(16-18-30)36(53)48-34(28-35(41)52)38(55)46-25-10-8-6-5-7-9-23-44-24-11-12-26-45-37(54)33(40)14-13-27-47-39(42)43/h15-22,33-34,44H,3-14,23-28,40H2,1-2H3,(H2,41,52)(H,45,54)(H,46,55)(H,48,53)(H4,42,43,47)/b50-49+/t33-,34-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of rat GluA1 flip isoform expressed in Xenopus laevis oocytes assessed as inhibition of L-Glu-evoked currents under dark condition at -80 ...				J Med Chem 31: 802-6 (1988) Article DOI: 10.1021/acs.jmedchem.8b00756 BindingDB Entry DOI: 10.7270/Q22R3QN5
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50018845 (CHEMBL3286869) Show SMILES NCCCNCCCCNCCCNCCCN(O)CCCNC(=O)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C26H47N7O2/c27-11-5-14-28-12-3-4-13-29-15-6-16-30-17-7-19-33(35)20-8-18-31-26(34)21-23-22-32-25-10-2-1-9-24(23)25/h1-2,9-10,22,28-30,32,35H,3-8,11-21,27H2,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced channel current at holding potential of ...				J Med Chem 57: 4940-9 (2014) Article DOI: 10.1021/jm5004705 BindingDB Entry DOI: 10.7270/Q29K4CT3
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50018846 (CHEMBL3286871) Show SMILES N[C@@H](CCCCNCCCNC(=O)[C@@H](N)CCCNC(N)=N)C(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2cccc(O)c12 |r| Show InChI InChI=1S/C34H58N12O6/c35-23(9-2-5-13-40-14-8-18-42-32(51)24(36)10-7-17-44-34(38)39)31(50)41-15-3-1-4-16-43-33(52)26(20-28(37)48)46-29(49)19-22-21-45-25-11-6-12-27(47)30(22)25/h6,11-12,21,23-24,26,40,45,47H,1-5,7-10,13-20,35-36H2,(H2,37,48)(H,41,50)(H,42,51)(H,43,52)(H,46,49)(H4,38,39,44)/t23-,24-,26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced channel current at holding potential of ...				J Med Chem 57: 4940-9 (2014) Article DOI: 10.1021/jm5004705 BindingDB Entry DOI: 10.7270/Q29K4CT3
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425996 (CHEMBL2314718) Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1c[nH]c2ccccc12 |r,wU:27.27,wD:1.0,(64.28,-71.95,;64.27,-73.49,;65.6,-74.27,;66.94,-73.5,;68.27,-74.28,;69.6,-73.5,;70.93,-74.27,;69.59,-71.96,;62.93,-74.26,;62.93,-75.8,;61.6,-73.48,;60.27,-74.26,;58.93,-73.49,;57.6,-74.27,;56.27,-73.5,;54.94,-74.28,;53.6,-73.51,;52.27,-74.29,;50.93,-73.52,;49.6,-74.3,;48.27,-73.53,;46.93,-74.3,;45.6,-73.52,;44.26,-74.29,;42.93,-73.51,;41.59,-74.28,;41.59,-75.82,;40.26,-73.5,;38.93,-74.27,;37.6,-73.49,;37.6,-71.95,;36.26,-74.26,;34.93,-73.48,;34.93,-71.93,;33.6,-71.16,;32.26,-71.93,;30.93,-71.16,;32.26,-73.47,;33.59,-74.24,;33.59,-75.78,;40.27,-71.96,;39.03,-71.05,;39.51,-69.59,;41.05,-69.6,;42.08,-68.47,;43.57,-68.78,;44.05,-70.25,;43.01,-71.39,;41.52,-71.06,)| Show InChI InChI=1S/C35H53N9O5/c36-28(15-20-42-35(37)38)33(48)40-18-10-4-8-17-39-16-7-2-1-3-9-19-41-34(49)32(27-23-43-29-12-6-5-11-26(27)29)44-31(47)21-24-13-14-25(45)22-30(24)46/h5-6,11-14,22-23,28,32,39,43,45-46H,1-4,7-10,15-21,36H2,(H,40,48)(H,41,49)(H,44,47)(H4,37,38,42)/t28-,32+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426005 (CHEMBL2314933) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-9-17-38-30(33)34)28(44)36-15-6-4-2-1-3-5-13-35-14-7-8-16-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50399431 (CHEMBL2178919) Show SMILES NCCCNCCCCNCCC(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C29H48N8O4/c30-12-8-15-32-13-6-7-14-33-18-11-27(39)34-16-4-1-5-17-35-29(41)25(20-26(31)38)37-28(40)19-22-21-36-24-10-3-2-9-23(22)24/h2-3,9-10,21,25,32-33,36H,1,4-8,11-20,30H2,(H2,31,38)(H,34,39)(H,35,41)(H,37,40)/t25-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...				J Med Chem 55: 10297-301 (2012) Article DOI: 10.1021/jm301255m BindingDB Entry DOI: 10.7270/Q27S7PXR
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425988 (CHEMBL2314712) Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCCCCNCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1c[nH]c2ccccc12 |r,wU:27.27,wD:1.0,(63.54,-116.3,;63.54,-117.84,;64.87,-118.62,;66.2,-117.85,;67.53,-118.62,;68.86,-117.85,;70.2,-118.61,;68.86,-116.31,;62.2,-118.61,;62.19,-120.15,;60.87,-117.83,;59.54,-118.61,;58.2,-117.84,;56.87,-118.62,;55.53,-117.85,;54.2,-118.63,;52.87,-117.86,;51.54,-118.64,;50.2,-117.87,;48.87,-118.65,;47.54,-117.87,;46.2,-118.64,;44.87,-117.86,;43.53,-118.63,;42.2,-117.85,;40.87,-118.62,;40.86,-120.16,;39.54,-117.84,;38.2,-118.61,;36.87,-117.83,;36.87,-116.29,;35.53,-118.6,;34.2,-117.82,;34.21,-116.27,;32.87,-115.5,;31.53,-116.27,;30.2,-115.5,;31.54,-117.81,;32.86,-118.59,;32.86,-120.13,;39.54,-116.3,;38.3,-115.39,;38.78,-113.92,;40.32,-113.93,;41.35,-112.8,;42.84,-113.12,;43.31,-114.59,;42.28,-115.72,;40.78,-115.39,)| Show InChI InChI=1S/C35H53N9O5/c36-28(15-20-42-35(37)38)33(48)40-18-8-4-2-1-3-7-16-39-17-9-10-19-41-34(49)32(27-23-43-29-12-6-5-11-26(27)29)44-31(47)21-24-13-14-25(45)22-30(24)46/h5-6,11-14,22-23,28,32,39,43,45-46H,1-4,7-10,15-21,36H2,(H,40,48)(H,41,49)(H,44,47)(H4,37,38,42)/t28-,32+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425995 (CHEMBL2314717) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccccc1-[#8] |r| Show InChI InChI=1S/C29H51N9O5/c30-22(13-18-37-29(32)33)27(42)35-16-8-4-2-1-3-7-14-34-15-9-10-17-36-28(43)23(20-25(31)40)38-26(41)19-21-11-5-6-12-24(21)39/h5-6,11-12,22-23,34,39H,1-4,7-10,13-20,30H2,(H2,31,40)(H,35,42)(H,36,43)(H,38,41)(H4,32,33,37)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA receptor, using radioligand [3H]- AMPA				J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425997 (CHEMBL2314719) Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1cnc[nH]1 |r,wU:27.27,wD:1.0,(63.05,-61.46,;63.04,-63,;64.37,-63.77,;65.71,-63.01,;67.04,-63.78,;68.37,-63.01,;69.7,-63.78,;68.36,-61.47,;61.7,-63.76,;61.7,-65.3,;60.37,-62.99,;59.04,-63.76,;57.71,-63,;56.38,-63.77,;55.04,-63.01,;53.71,-63.78,;52.37,-63.02,;51.04,-63.79,;49.7,-63.03,;48.37,-63.8,;47.04,-63.04,;45.7,-63.8,;44.37,-63.03,;43.03,-63.79,;41.7,-63.02,;40.37,-63.78,;40.36,-65.32,;39.03,-63.01,;37.7,-63.77,;36.37,-63,;36.37,-61.46,;35.03,-63.76,;33.7,-62.99,;33.71,-61.44,;32.37,-60.67,;31.03,-61.44,;29.7,-60.67,;31.04,-62.98,;32.36,-63.75,;32.36,-65.29,;39.04,-61.47,;37.8,-60.56,;38.28,-59.1,;39.82,-59.11,;40.29,-60.57,)| Show InChI InChI=1S/C30H50N10O5/c31-23(11-16-38-30(32)33)28(44)36-14-8-4-6-13-34-12-5-2-1-3-7-15-37-29(45)27(24-19-35-20-39-24)40-26(43)17-21-9-10-22(41)18-25(21)42/h9-10,18-20,23,27,34,41-42H,1-8,11-17,31H2,(H,35,39)(H,36,44)(H,37,45)(H,40,43)(H4,32,33,38)/t23-,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426007 (CHEMBL2314935) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-9-17-38-30(33)34)28(44)36-15-7-3-1-5-13-35-14-6-2-4-8-16-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50399430 (CHEMBL2178920) Show SMILES NCCCNCCCCNCCC(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2cccc(O)c12 |r| Show InChI InChI=1S/C29H48N8O5/c30-11-7-14-32-12-4-5-13-33-17-10-26(40)34-15-2-1-3-16-35-29(42)23(19-25(31)39)37-27(41)18-21-20-36-22-8-6-9-24(38)28(21)22/h6,8-9,20,23,32-33,36,38H,1-5,7,10-19,30H2,(H2,31,39)(H,34,40)(H,35,42)(H,37,41)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...				J Med Chem 55: 10297-301 (2012) Article DOI: 10.1021/jm301255m BindingDB Entry DOI: 10.7270/Q27S7PXR
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50018844 (CHEMBL3286866) Show SMILES CN(CCCC[C@H](N)C(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2cccc(O)c12)CCCNC(=O)[C@@H](N)CCCNC(N)=N |r| Show InChI InChI=1S/C35H60N12O6/c1-47(19-9-17-42-33(52)25(37)11-8-16-44-35(39)40)18-6-3-10-24(36)32(51)41-14-4-2-5-15-43-34(53)27(21-29(38)49)46-30(50)20-23-22-45-26-12-7-13-28(48)31(23)26/h7,12-13,22,24-25,27,45,48H,2-6,8-11,14-21,36-37H2,1H3,(H2,38,49)(H,41,51)(H,42,52)(H,43,53)(H,46,50)(H4,39,40,44)/t24-,25-,27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced channel current at holding potential of ...				J Med Chem 57: 4940-9 (2014) Article DOI: 10.1021/jm5004705 BindingDB Entry DOI: 10.7270/Q29K4CT3
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425989 (CHEMBL2314713) Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCCCCNCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1cnc[nH]1 |r,wU:27.27,wD:1.0,(63.95,-107.91,;63.94,-109.45,;65.27,-110.22,;66.61,-109.46,;67.94,-110.23,;69.27,-109.46,;70.6,-110.22,;69.26,-107.92,;62.6,-110.21,;62.6,-111.75,;61.27,-109.44,;59.94,-110.21,;58.61,-109.45,;57.27,-110.22,;55.94,-109.46,;54.61,-110.23,;53.27,-109.47,;51.94,-110.24,;50.6,-109.48,;49.27,-110.25,;47.94,-109.48,;46.6,-110.24,;45.27,-109.47,;43.94,-110.23,;42.61,-109.46,;41.27,-110.22,;41.26,-111.76,;39.94,-109.45,;38.6,-110.21,;37.27,-109.44,;37.28,-107.9,;35.94,-110.2,;34.6,-109.43,;34.61,-107.88,;33.27,-107.11,;31.94,-107.88,;30.6,-107.11,;31.94,-109.42,;33.27,-110.19,;33.26,-111.73,;39.94,-107.91,;38.7,-107,;39.18,-105.53,;40.72,-105.54,;41.19,-107,)| Show InChI InChI=1S/C30H50N10O5/c31-23(11-16-38-30(32)33)28(44)36-14-6-4-2-1-3-5-12-34-13-7-8-15-37-29(45)27(24-19-35-20-39-24)40-26(43)17-21-9-10-22(41)18-25(21)42/h9-10,18-20,23,27,34,41-42H,1-8,11-17,31H2,(H,35,39)(H,36,44)(H,37,45)(H,40,43)(H4,32,33,38)/t23-,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426000 (CHEMBL2311573) Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2ccccc12 |r,wU:27.31,wD:1.0,(62.02,-79.67,;62.01,-81.21,;63.34,-81.98,;64.68,-81.22,;66.01,-81.99,;67.34,-81.22,;68.68,-81.98,;67.34,-79.68,;60.68,-81.97,;60.67,-83.51,;59.35,-81.2,;58.02,-81.97,;56.68,-81.21,;55.35,-81.98,;54.01,-81.22,;52.68,-81.99,;51.34,-81.23,;50.01,-82,;48.68,-81.24,;47.35,-82.01,;46.01,-81.25,;44.67,-82.01,;43.34,-81.24,;42.01,-82,;40.68,-81.23,;39.34,-81.99,;39.33,-83.53,;38.01,-81.22,;38.01,-79.68,;39.35,-78.91,;40.68,-79.69,;39.36,-77.37,;36.67,-81.98,;35.34,-81.21,;35.35,-79.67,;34,-81.97,;32.67,-81.2,;31.26,-81.81,;30.23,-80.66,;31,-79.33,;30.54,-77.88,;31.57,-76.74,;33.07,-77.07,;33.54,-78.53,;32.5,-79.66,)| Show InChI InChI=1S/C31H52N10O4/c32-24(13-18-39-31(34)35)29(44)37-16-10-4-8-15-36-14-7-2-1-3-9-17-38-30(45)26(20-27(33)42)41-28(43)19-22-21-40-25-12-6-5-11-23(22)25/h5-6,11-12,21,24,26,36,40H,1-4,7-10,13-20,32H2,(H2,33,42)(H,37,44)(H,38,45)(H,41,43)(H4,34,35,39)/t24-,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50458948 (CHEMBL4204422) Show SMILES CCN(CC)c1ccc(cc1)\N=N\c1ccc(cc1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCCCCCCNCCCCNC(=O)[C@@H](N)CCCNC(N)=N |r| Show InChI InChI=1S/C39H64N12O4/c1-3-51(4-2)32-21-19-31(20-22-32)50-49-30-17-15-29(16-18-30)36(53)48-34(28-35(41)52)38(55)46-25-10-8-6-5-7-9-23-44-24-11-12-26-45-37(54)33(40)14-13-27-47-39(42)43/h15-22,33-34,44H,3-14,23-28,40H2,1-2H3,(H2,41,52)(H,45,54)(H,46,55)(H,48,53)(H4,42,43,47)/b50-49+/t33-,34-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of rat GluA1 flip isoform expressed in Xenopus laevis oocytes assessed as inhibition of L-Glu-evoked currents under illumination with blue...				J Med Chem 31: 802-6 (1988) Article DOI: 10.1021/acs.jmedchem.8b00756 BindingDB Entry DOI: 10.7270/Q22R3QN5
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425991 (CHEMBL2314934) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C27H48N8O5/c28-22(11-16-34-27(29)30)26(40)33-15-6-4-2-1-3-5-12-31-13-7-8-14-32-25(39)19-35-24(38)17-20-9-10-21(36)18-23(20)37/h9-10,18,22,31,36-37H,1-8,11-17,19,28H2,(H,32,39)(H,33,40)(H,35,38)(H4,29,30,34)/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50105843 (2-Amino-N-{3-[4-(3-amino-propylamino)-butylamino]-...) Show SMILES NCCCNCCCCNCCC(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1ccc(O)cc1O Show InChI InChI=1S/C27H47N7O6/c28-10-6-13-30-11-4-5-12-31-16-9-25(38)32-14-2-1-3-15-33-27(40)22(19-24(29)37)34-26(39)17-20-7-8-21(35)18-23(20)36/h7-8,18,22,30-31,35-36H,1-6,9-17,19,28H2,(H2,29,37)(H,32,38)(H,33,40)(H,34,39)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...				J Med Chem 55: 10297-301 (2012) Article DOI: 10.1021/jm301255m BindingDB Entry DOI: 10.7270/Q27S7PXR
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426003 (CHEMBL2314931) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccccc1-[#8] |r| Show InChI InChI=1S/C29H51N9O5/c30-22(13-18-37-29(32)33)27(42)35-16-10-4-8-15-34-14-7-2-1-3-9-17-36-28(43)23(20-25(31)40)38-26(41)19-21-11-5-6-12-24(21)39/h5-6,11-12,22-23,34,39H,1-4,7-10,13-20,30H2,(H2,31,40)(H,35,42)(H,36,43)(H,38,41)(H4,32,33,37)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50316373 (Argiotoxin-636 | CHEMBL1098240) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C29H52N10O6/c30-22(7-4-15-38-29(32)33)27(44)36-16-6-13-35-12-5-11-34-10-2-1-3-14-37-28(45)23(19-25(31)42)39-26(43)17-20-8-9-21(40)18-24(20)41/h8-9,18,22-23,34-35,40-41H,1-7,10-17,19,30H2,(H2,31,42)(H,36,44)(H,37,45)(H,39,43)(H4,32,33,38)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50316373 (Argiotoxin-636 | CHEMBL1098240) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C29H52N10O6/c30-22(7-4-15-38-29(32)33)27(44)36-16-6-13-35-12-5-11-34-10-2-1-3-14-37-28(45)23(19-25(31)42)39-26(43)17-20-8-9-21(40)18-24(20)41/h8-9,18,22-23,34-35,40-41H,1-7,10-17,19,30H2,(H2,31,42)(H,36,44)(H,37,45)(H,39,43)(H4,32,33,38)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 expressed in xenopus laevis oocytes assessed as inhibition of glutamate-evoked current at membrane potential of -60 mV by vol...				J Nat Prod 74: 483-6 (2011) Article DOI: 10.1021/np100746w BindingDB Entry DOI: 10.7270/Q2KK9CWC
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426006 (CHEMBL2314936) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-9-17-38-30(33)34)28(44)36-15-7-3-1-2-5-13-35-14-6-4-8-16-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425992 (CHEMBL2314940) Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCCCCNCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2ccccc12 |r,wU:27.31,wD:1.0,(63.09,-105.91,;63.08,-107.45,;64.41,-108.23,;65.75,-107.46,;67.08,-108.23,;68.41,-107.46,;69.75,-108.22,;68.4,-105.92,;61.74,-108.22,;61.74,-109.76,;60.41,-107.44,;59.08,-108.22,;57.75,-107.45,;56.42,-108.23,;55.08,-107.46,;53.75,-108.24,;52.41,-107.47,;51.08,-108.25,;49.74,-107.48,;48.41,-108.26,;47.08,-107.48,;45.75,-108.25,;44.42,-107.47,;43.08,-108.24,;41.75,-107.46,;40.41,-108.23,;40.41,-109.77,;39.08,-107.45,;39.09,-105.91,;40.42,-105.15,;41.75,-105.92,;40.43,-103.61,;37.74,-108.22,;36.41,-107.44,;36.42,-105.9,;35.08,-108.21,;33.75,-107.43,;32.33,-108.05,;31.3,-106.9,;32.08,-105.57,;31.61,-104.11,;32.64,-102.98,;34.15,-103.3,;34.61,-104.77,;33.58,-105.9,)| Show InChI InChI=1S/C31H52N10O4/c32-24(13-18-39-31(34)35)29(44)37-16-8-4-2-1-3-7-14-36-15-9-10-17-38-30(45)26(20-27(33)42)41-28(43)19-22-21-40-25-12-6-5-11-23(22)25/h5-6,11-12,21,24,26,36,40H,1-4,7-10,13-20,32H2,(H2,33,42)(H,37,44)(H,38,45)(H,41,43)(H4,34,35,39)/t24-,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426009 (CHEMBL2314938) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-9-17-38-30(33)34)28(44)36-16-8-7-14-35-13-5-3-1-2-4-6-15-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425994 (CHEMBL2314716) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1 |r| Show InChI InChI=1S/C29H51N9O5/c30-23(13-18-37-29(32)33)27(42)35-16-6-4-2-1-3-5-14-34-15-7-8-17-36-28(43)24(20-25(31)40)38-26(41)19-21-9-11-22(39)12-10-21/h9-12,23-24,34,39H,1-8,13-20,30H2,(H2,31,40)(H,35,42)(H,36,43)(H,38,41)(H4,32,33,37)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425993 (CHEMBL2314715) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccccc1 |r| Show InChI InChI=1S/C29H51N9O4/c30-23(14-19-37-29(32)33)27(41)35-17-9-4-2-1-3-8-15-34-16-10-11-18-36-28(42)24(21-25(31)39)38-26(40)20-22-12-6-5-7-13-22/h5-7,12-13,23-24,34H,1-4,8-11,14-21,30H2,(H2,31,39)(H,35,41)(H,36,42)(H,38,40)(H4,32,33,37)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426002 (CHEMBL2314929) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1 |r| Show InChI InChI=1S/C29H51N9O5/c30-23(13-18-37-29(32)33)27(42)35-16-8-4-6-15-34-14-5-2-1-3-7-17-36-28(43)24(20-25(31)40)38-26(41)19-21-9-11-22(39)12-10-21/h9-12,23-24,34,39H,1-8,13-20,30H2,(H2,31,40)(H,35,42)(H,36,43)(H,38,41)(H4,32,33,37)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425999 (CHEMBL2314928) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C27H48N8O5/c28-22(11-16-34-27(29)30)26(40)33-15-8-4-6-13-31-12-5-2-1-3-7-14-32-25(39)19-35-24(38)17-20-9-10-21(36)18-23(20)37/h9-10,18,22,31,36-37H,1-8,11-17,19,28H2,(H,32,39)(H,33,40)(H,35,38)(H4,29,30,34)/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426008 (CHEMBL2314937) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-9-17-38-30(33)34)28(44)36-15-8-4-6-14-35-13-5-2-1-3-7-16-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50018843 (CHEMBL3286865) Show SMILES C[N+](C)(CCCC[C@H](N)C(=O)NCCCCCNC(=O)[C@H](CC(N)=O)NC(=O)Cc1c[nH]c2cccc(O)c12)CCCNC(=O)[C@@H](N)CCCNC(N)=N |r| Show InChI InChI=1S/C36H62N12O6/c1-48(2,20-10-18-43-34(53)26(38)12-9-17-45-36(40)41)19-7-4-11-25(37)33(52)42-15-5-3-6-16-44-35(54)28(22-30(39)50)47-31(51)21-24-23-46-27-13-8-14-29(49)32(24)27/h8,13-14,23,25-26,28,46H,3-7,9-12,15-22,37-38H2,1-2H3,(H10-,39,40,41,42,43,44,45,47,49,50,51,52,53,54)/p+1/t25-,26-,28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced channel current at holding potential of ...				J Med Chem 57: 4940-9 (2014) Article DOI: 10.1021/jm5004705 BindingDB Entry DOI: 10.7270/Q29K4CT3
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426001 (CHEMBL2314930) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccccc1 |r| Show InChI InChI=1S/C29H51N9O4/c30-23(14-19-37-29(32)33)27(41)35-17-11-5-9-16-34-15-8-2-1-3-10-18-36-28(42)24(21-25(31)39)38-26(40)20-22-12-6-4-7-13-22/h4,6-7,12-13,23-24,34H,1-3,5,8-11,14-21,30H2,(H2,31,39)(H,35,41)(H,36,42)(H,38,40)(H4,32,33,37)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50316373 (Argiotoxin-636 | CHEMBL1098240) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C29H52N10O6/c30-22(7-4-15-38-29(32)33)27(44)36-16-6-13-35-12-5-11-34-10-2-1-3-14-37-28(45)23(19-25(31)42)39-26(43)17-20-8-9-21(40)18-24(20)41/h8-9,18,22-23,34-35,40-41H,1-7,10-17,19,30H2,(H2,31,42)(H,36,44)(H,37,45)(H,39,43)(H4,32,33,38)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...				J Med Chem 55: 10297-301 (2012) Article DOI: 10.1021/jm301255m BindingDB Entry DOI: 10.7270/Q27S7PXR
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50399433 (CHEMBL2178917) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H52N10O7/c31-22(7-6-15-39-30(33)34)28(46)37-14-5-4-11-35-16-10-26(44)36-12-2-1-3-13-38-29(47)23(19-25(32)43)40-27(45)17-20-8-9-21(41)18-24(20)42/h8-9,18,22-23,35,41-42H,1-7,10-17,19,31H2,(H2,32,43)(H,36,44)(H,37,46)(H,38,47)(H,40,45)(H4,33,34,39)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...				J Med Chem 55: 10297-301 (2012) Article DOI: 10.1021/jm301255m BindingDB Entry DOI: 10.7270/Q27S7PXR
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425998 (CHEMBL2314927) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C29H50N8O7/c30-22(11-16-36-29(31)32)27(43)34-14-8-4-6-13-33-12-5-2-1-3-7-15-35-28(44)23(19-26(41)42)37-25(40)17-20-9-10-21(38)18-24(20)39/h9-10,18,22-23,33,38-39H,1-8,11-17,19,30H2,(H,34,43)(H,35,44)(H,37,40)(H,41,42)(H4,31,32,36)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426004 (CHEMBL2314932) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-8-16-38-30(33)34)28(44)36-15-7-5-3-1-2-4-6-13-35-14-9-17-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50128264 ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) Show SMILES NC(Cc1o[nH]c(=O)c1Cl)C(O)=O Show InChI InChI=1S/C6H7ClN2O4/c7-4-3(13-9-5(4)10)1-2(8)6(11)12/h2H,1,8H2,(H,9,10)(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA receptor, using radioligand [3H]- AMPA				J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50426010 (CHEMBL2314939) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C30H53N9O6/c31-23(10-8-16-38-30(33)34)28(44)36-17-9-14-35-13-6-4-2-1-3-5-7-15-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	454	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50316374 (CHEMBL1096289 | N-(4-hydroxyphenylpropanyl)-spermi...) Show SMILES NCCCNCCCCNCCCNC(=O)CCc1ccccc1 Show InChI InChI=1S/C19H34N4O/c20-12-6-15-21-13-4-5-14-22-16-7-17-23-19(24)11-10-18-8-2-1-3-9-18/h1-3,8-9,21-22H,4-7,10-17,20H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 receptor expressed in Xenopus oocytes assessed as inhibition of 300 uM kainate-induced current				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50425990 (CHEMBL2314714) Show SMILES [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C29H50N8O7/c30-22(11-16-36-29(31)32)27(43)34-14-6-4-2-1-3-5-12-33-13-7-8-15-35-28(44)23(19-26(41)42)37-25(40)17-20-9-10-21(38)18-24(20)39/h9-10,18,22-23,33,38-39H,1-8,11-17,19,30H2,(H,34,43)(H,35,44)(H,37,40)(H,41,42)(H4,31,32,36)/t22-,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	466	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	613	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Carlo Bo Curated by ChEMBL					Assay Description Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA				J Med Chem 48: 6887-96 (2005) Article DOI: 10.1021/jm058018d BindingDB Entry DOI: 10.7270/Q28C9X1X
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50017244 ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) Show SMILES NC(Cc1o[nH]c(=O)c1Br)C(O)=O Show InChI InChI=1S/C6H7BrN2O4/c7-4-3(13-9-5(4)10)1-2(8)6(11)12/h2H,1,8H2,(H,9,10)(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA receptor, using radioligand [3H]- AMPA				J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50399432 (CHEMBL2178918) Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C35H60N12O9/c1-22(46-31(53)21-45-33(55)25(36)8-7-16-44-35(38)39)32(54)42-15-6-5-12-40-17-11-29(51)41-13-3-2-4-14-43-34(56)26(20-28(37)50)47-30(52)18-23-9-10-24(48)19-27(23)49/h9-10,19,22,25-26,40,48-49H,2-8,11-18,20-21,36H2,1H3,(H2,37,50)(H,41,51)(H,42,54)(H,43,56)(H,45,55)(H,46,53)(H,47,52)(H4,38,39,44)/t22-,25-,26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...				J Med Chem 55: 10297-301 (2012) Article DOI: 10.1021/jm301255m BindingDB Entry DOI: 10.7270/Q27S7PXR
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50094298 (CHEMBL16117 | N-[(S)-1-{3-[4-(3-Amino-propylamino)...) Show SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCNCCCCNCCCN Show InChI InChI=1S/C23H41N5O3/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-6-16-26-14-4-3-13-25-15-5-12-24/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50316373 (Argiotoxin-636 | CHEMBL1098240) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8] |r| Show InChI InChI=1S/C29H52N10O6/c30-22(7-4-15-38-29(32)33)27(44)36-16-6-13-35-12-5-11-34-10-2-1-3-14-37-28(45)23(19-25(31)42)39-26(43)17-20-8-9-21(40)18-24(20)41/h8-9,18,22-23,34-35,40-41H,1-7,10-17,19,30H2,(H2,31,42)(H,36,44)(H,37,45)(H,39,43)(H4,32,33,38)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324405 ((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2cc3ccccc3cc2c1=O Show InChI InChI=1S/C27H17N3O5/c31-26-23-15-19-5-1-2-6-20(19)16-24(23)28-25(13-8-17-4-3-7-22(14-17)30(34)35)29(26)21-11-9-18(10-12-21)27(32)33/h1-16H,(H,32,33)/b13-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324463 ((E)-3-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1cccc(c1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-9-2-3-10-19(18)24-21(13-12-15-6-1-4-11-20(15)26(30)31)25(22)17-8-5-7-16(14-17)23(28)29/h1-14H,(H,28,29)/b13-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324404 ((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-phenylquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H19N3O5/c33-28-25-18-22(20-6-2-1-3-7-20)12-15-26(25)30-27(16-9-19-5-4-8-24(17-19)32(36)37)31(28)23-13-10-21(11-14-23)29(34)35/h1-18H,(H,34,35)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324461 ((E)-4-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O Show InChI InChI=1S/C23H15N3O5/c27-22-18-6-2-3-7-19(18)24-21(14-11-15-5-1-4-8-20(15)26(30)31)25(22)17-12-9-16(10-13-17)23(28)29/h1-14H,(H,28,29)/b14-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324397 ((E)-4-(6-Fluoro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(F)cc2c1=O Show InChI InChI=1S/C23H14FN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324392 ((E)-4-(6-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(Cl)cc2c1=O Show InChI InChI=1S/C23H14ClN3O5/c24-16-7-10-20-19(13-16)22(28)26(17-8-5-15(6-9-17)23(29)30)21(25-20)11-4-14-2-1-3-18(12-14)27(31)32/h1-13H,(H,29,30)/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair

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