Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455611 (CHEMBL4212424) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455569 (CHEMBL4202753) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455593 (CHEMBL4208685) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455592 (CHEMBL4206065) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455602 (CHEMBL4216507) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human PKCiota using ERMRPRKRQGSVRRRV as substrate by [gamma-33P]-ATP assay | Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455566 (CHEMBL4208028) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of human PKCiota using ERMRPRKRQGSVRRRV as substrate by [gamma-33P]-ATP assay | Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50536679 (CHEMBL4568087) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co. Curated by ChEMBL | Assay Description Inhibition of full-length recombinant human His-tagged PRKCI expressed in baculovirus expression system by Z'-LYTE assay | Bioorg Med Chem Lett 26: 4362-6 (2016) Article DOI: 10.1016/j.bmcl.2016.02.003 BindingDB Entry DOI: 10.7270/Q2NP27X5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455589 (CHEMBL4213984) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455594 (CHEMBL4212934) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50543619 (CHEMBL4637651) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human aPKCiota using CREBtide as substrate incubated for 3 hrs in presence of ATP by kinase Glo luminescent ass... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115480 BindingDB Entry DOI: 10.7270/Q2HM5D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455610 (CHEMBL4211722) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455588 (CHEMBL4208982) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526595 (CHEMBL4517782) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455568 (CHEMBL4215492) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526582 (CHEMBL4471416) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 364 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibition of human PKCiota | J Biol Chem 282: 33052-63 (2007) Article DOI: 10.1074/jbc.M707233200 BindingDB Entry DOI: 10.7270/Q2TB16NW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455590 (CHEMBL4206023) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526584 (CHEMBL4441139) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50536681 (CHEMBL4552628) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co. Curated by ChEMBL | Assay Description Inhibition of full-length recombinant human His-tagged PRKCI expressed in baculovirus expression system by Z'-LYTE assay | Bioorg Med Chem Lett 26: 4362-6 (2016) Article DOI: 10.1016/j.bmcl.2016.02.003 BindingDB Entry DOI: 10.7270/Q2NP27X5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455587 (CHEMBL4205851) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM139465 (US8889672, 317-080-001) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Penn State University College of Medicine Curated by ChEMBL | Assay Description Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assay | Bioorg Med Chem Lett 23: 3034-8 (2013) Article DOI: 10.1016/j.bmcl.2013.03.019 BindingDB Entry DOI: 10.7270/Q28918S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM139469 (US8889672, 317-052-004) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Penn State University College of Medicine Curated by ChEMBL | Assay Description Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assay | Bioorg Med Chem Lett 23: 3034-8 (2013) Article DOI: 10.1016/j.bmcl.2013.03.019 BindingDB Entry DOI: 10.7270/Q28918S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50192071 ((13R,15S)-13-methyl-16-oxa-8,9,12,22,24-pentaazahe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of PKCiota | Bioorg Med Chem Lett 16: 5122-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.026 BindingDB Entry DOI: 10.7270/Q2K35VF0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455564 (CHEMBL4211820) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50536675 (CHEMBL4569508) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co. Curated by ChEMBL | Assay Description Inhibition of full-length recombinant human His-tagged PRKCI expressed in baculovirus expression system by Z'-LYTE assay | Bioorg Med Chem Lett 26: 4362-6 (2016) Article DOI: 10.1016/j.bmcl.2016.02.003 BindingDB Entry DOI: 10.7270/Q2NP27X5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM139467 (US8889672, 268-020-002) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Penn State University College of Medicine Curated by ChEMBL | Assay Description Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assay | Bioorg Med Chem Lett 23: 3034-8 (2013) Article DOI: 10.1016/j.bmcl.2013.03.019 BindingDB Entry DOI: 10.7270/Q28918S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM2683 (2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 3.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibition of human PKCiota | J Biol Chem 282: 33052-63 (2007) Article DOI: 10.1074/jbc.M707233200 BindingDB Entry DOI: 10.7270/Q2TB16NW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50543619 (CHEMBL4637651) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human aPKCiota in presence of ATP at Km concentration by radiometric assay | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115480 BindingDB Entry DOI: 10.7270/Q2HM5D1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455570 (CHEMBL4214431) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM139464 (US8889672, 194-074-007 | US8889672, PKCzI-diMeO) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Penn State University College of Medicine Curated by ChEMBL | Assay Description Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assay | Bioorg Med Chem Lett 23: 3034-8 (2013) Article DOI: 10.1016/j.bmcl.2013.03.019 BindingDB Entry DOI: 10.7270/Q28918S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455585 (CHEMBL4217980) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50536678 (CHEMBL4550702) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co. Curated by ChEMBL | Assay Description Inhibition of full-length recombinant human His-tagged PRKCI expressed in baculovirus expression system by Z'-LYTE assay | Bioorg Med Chem Lett 26: 4362-6 (2016) Article DOI: 10.1016/j.bmcl.2016.02.003 BindingDB Entry DOI: 10.7270/Q2NP27X5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455627 (CHEMBL4215555) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455586 (CHEMBL4214403) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455584 (CHEMBL4216980) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455620 (CHEMBL4208713) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50519662 (CHEMBL4438748) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human PKCiota using ERMRPRKRQGSVRR as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometr... | J Med Chem 62: 10691-10710 (2019) Article DOI: 10.1021/acs.jmedchem.9b01143 BindingDB Entry DOI: 10.7270/Q2MC93FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50499634 (CHEMBL3741589) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of PKCiota (unknown origin) | J Med Chem 58: 9154-70 (2015) Article DOI: 10.1021/acs.jmedchem.5b00928 BindingDB Entry DOI: 10.7270/Q2PZ5CV4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50135286 (CHEMBL3745885) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human PKCiota using [ERMRPRKRQGSVRRRV] as substrate | Bioorg Med Chem 24: 521-44 (2016) Article DOI: 10.1016/j.bmc.2015.11.045 BindingDB Entry DOI: 10.7270/Q24Q7WT8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50429867 (CHEMBL2333365) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exelixis Curated by ChEMBL | Assay Description Inhibition of PKCiota (unknown origin) | J Med Chem 56: 2218-34 (2013) Article DOI: 10.1021/jm3007933 BindingDB Entry DOI: 10.7270/Q2ZC847X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50208911 (CHEMBL3884319) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co. Curated by ChEMBL | Assay Description Inhibition of human recombinant full length His-tagged PRKCI expressed in baculovirus expression system | Bioorg Med Chem Lett 27: 114-120 (2017) Article DOI: 10.1016/j.bmcl.2016.08.068 BindingDB Entry DOI: 10.7270/Q2N018JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM218807 (PS432) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.69E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Universitätsklinikum Frankfurt | Assay Description Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2... | ACS Chem Biol 12: 564-573 (2017) Article DOI: 10.1021/acschembio.6b00827 BindingDB Entry DOI: 10.7270/Q2J96575 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526588 (CHEMBL4520505) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50455583 (CHEMBL4204387) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL | Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte... | J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526591 (CHEMBL4543879) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526590 (CHEMBL4450200) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526592 (CHEMBL4547613) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C iota type (Homo sapiens (Human)) | BDBM50526585 (CHEMBL4440509) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTAR Curated by ChEMBL | Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR... | ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0 | |||||||||||
More data for this Ligand-Target Pair |
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