Compile Data Set for Download or QSAR

Found 11 hits of kd for UniProtKB: P05067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481160 (US10906900, Reference 28) Show SMILES CN(CCF)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1 Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM50492518 (Florbetapir | US10906900, AV45) Show SMILES CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1 Show InChI InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.68	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481151 (US10906900, Reference 22c) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ncccc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)15-9-6-13(7-10-15)5-8-14-12-17-16(19-14)4-3-11-18-17/h3-4,6-7,9-12,19H,1-2H3	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481159 (US10906900, Reference 25c) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccc(F)nc1 Show InChI InChI=1S/C22H17FN4/c1-27(2)19-9-4-15(5-10-19)3-8-18-13-16-6-11-20(26-22(16)25-18)17-7-12-21(23)24-14-17/h4-7,9-14H,1-2H3,(H,25,26)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481156 (US10906900, Reference 22d) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2cnccc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-7-4-13(5-8-16)3-6-15-11-14-12-18-10-9-17(14)19-15/h4-5,7-12,19H,1-2H3	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM50185987 (2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...) Show SMILES [#6]-[#7](-[#6]-[#6]F)-c1ccc2cc(ccc2c1)-[#6](\[#6])=[#6](\C#N)C#N Show InChI InChI=1S/C18H16FN3/c1-13(17(11-20)12-21)14-3-4-16-10-18(22(2)8-7-19)6-5-15(16)9-14/h3-6,9-10H,7-8H2,1-2H3	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481158 (US10906900, Reference 25b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C21H17N3S/c1-24(2)19-8-4-15(5-9-19)3-7-18-13-16-6-10-20(23-21(16)22-18)17-11-12-25-14-17/h4-6,8-14H,1-2H3,(H,22,23)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481157 (US10906900, Reference 25a) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1cccs1 Show InChI InChI=1S/C21H17N3S/c1-24(2)18-10-6-15(7-11-18)5-9-17-14-16-8-12-19(23-21(16)22-17)20-4-3-13-25-20/h3-4,6-8,10-14H,1-2H3,(H,22,23)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481150 (US10906900, Reference 22b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccncc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-7-4-13(5-8-16)3-6-15-11-14-9-10-18-12-17(14)19-15/h4-5,7-12,19H,1-2H3	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481149 (US10906900, Reference 22a) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-9-6-13(7-10-16)5-8-15-12-14-4-3-11-18-17(14)19-15/h3-4,6-7,9-12H,1-2H3,(H,18,19)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	11.8	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human))	BDBM481153 (US10906900, Reference 22f) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(F)nc2[nH]1 Show InChI InChI=1S/C17H14FN3/c1-21(2)15-8-4-12(5-9-15)3-7-14-11-13-6-10-16(18)20-17(13)19-14/h4-6,8-11H,1-2H3,(H,19,20)	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16.8	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair