Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 10329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528351 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-3- ethyl...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.214	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528352 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-isopropy...) Show SMILES CCCCn1c2cc(cnc2n2c(nnc2c1=O)C1(CC1)C1CC1)C(C)C Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528349 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-2,3- dim...) Show SMILES CCCCn1c2cc(C)c(C)nc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.343	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528331 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-methylpy...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.366	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528352 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-isopropy...) Show SMILES CCCCn1c2cc(cnc2n2c(nnc2c1=O)C1(CC1)C1CC1)C(C)C Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.396	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528349 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-2,3- dim...) Show SMILES CCCCn1c2cc(C)c(C)nc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528331 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-methylpy...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.406	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528351 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-3- ethyl...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.419	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528355 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-2-methylpy...) Show SMILES CCCCn1c2ccc(C)nc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.816	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528353 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-((2-(tri...) Show SMILES CCCCn1c2cc(CO)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.928	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528353 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-((2-(tri...) Show SMILES CCCCn1c2cc(CO)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.996	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528355 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-2-methylpy...) Show SMILES CCCCn1c2ccc(C)nc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528353 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-((2-(tri...) Show SMILES CCCCn1c2cc(CO)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528354 (5-Butyl-3- (hydroxymethyl)-9- (1- methylcyclopropy...) Show SMILES CCCCn1c2cc(CO)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528350 (5-butyl-3-ethyl-9-(1-methylcyclopropyl)pyrido[3,2-...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528351 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-3- ethyl...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528349 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-2,3- dim...) Show SMILES CCCCn1c2cc(C)c(C)nc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528332 (5-Butyl-3- methyl-9-(1- (trifluoromethyl) cyclopro...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528348 (5-butyl-3-methyl-9-(1-methylcyclopropyl)pyrido[3,2...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528352 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-isopropy...) Show SMILES CCCCn1c2cc(cnc2n2c(nnc2c1=O)C1(CC1)C1CC1)C(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528333 (9-([1,1'- Bi(cyclopropan)]- 1-yl)-3- methyl-5- pro...) Show SMILES CCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528347 (9-([1,1'-bi(cylopropan)]-1-yl)-5-(cyclopropylmethy...) Show SMILES Oc1ccc2n(CC3CC3)c(=O)c3nnc(n3c2n1)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528333 (9-([1,1'- Bi(cyclopropan)]- 1-yl)-3- methyl-5- pro...) Show SMILES CCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.59	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528347 (9-([1,1'-bi(cylopropan)]-1-yl)-5-(cyclopropylmethy...) Show SMILES Oc1ccc2n(CC3CC3)c(=O)c3nnc(n3c2n1)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528347 (9-([1,1'-bi(cylopropan)]-1-yl)-5-(cyclopropylmethy...) Show SMILES Oc1ccc2n(CC3CC3)c(=O)c3nnc(n3c2n1)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528355 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-2-methylpy...) Show SMILES CCCCn1c2ccc(C)nc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528333 (9-([1,1'- Bi(cyclopropan)]- 1-yl)-3- methyl-5- pro...) Show SMILES CCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528331 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-methylpy...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528350 (5-butyl-3-ethyl-9-(1-methylcyclopropyl)pyrido[3,2-...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528332 (5-Butyl-3- methyl-9-(1- (trifluoromethyl) cyclopro...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C(F)(F)F Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528350 (5-butyl-3-ethyl-9-(1-methylcyclopropyl)pyrido[3,2-...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528348 (5-butyl-3-methyl-9-(1-methylcyclopropyl)pyrido[3,2...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528332 (5-Butyl-3- methyl-9-(1- (trifluoromethyl) cyclopro...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(CC1)C(F)(F)F Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528348 (5-butyl-3-methyl-9-(1-methylcyclopropyl)pyrido[3,2...) Show SMILES CCCCn1c2cc(C)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528354 (5-Butyl-3- (hydroxymethyl)-9- (1- methylcyclopropy...) Show SMILES CCCCn1c2cc(CO)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528354 (5-Butyl-3- (hydroxymethyl)-9- (1- methylcyclopropy...) Show SMILES CCCCn1c2cc(CO)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Homo sapiens (Human))	BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) Show SMILES CCC(Cn1c2cccnc2n2c(nnc2c1=O)C1(CC1)C1CC1)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha/beta (Homo sapiens (Human))	BDBM528352 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-isopropy...) Show SMILES CCCCn1c2cc(cnc2n2c(nnc2c1=O)C1(CC1)C1CC1)C(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	611	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following phosphodiesterase activities are measured using [3H]cGMP as reaction substrate: human PDE6A/6B. The catalytic active form of human PDE6...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM528351 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-3- ethyl...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	675	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following phosphodiesterase activities are measured using [3H]cAMP as reaction substrate: human PDE3A (catalytic domain) and human PDE4D. Both en...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM528350 (5-butyl-3-ethyl-9-(1-methylcyclopropyl)pyrido[3,2-...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(C)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	957	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following phosphodiesterase activities are measured using [3H]cAMP as reaction substrate: human PDE3A (catalytic domain) and human PDE4D. Both en...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM528352 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-isopropy...) Show SMILES CCCCn1c2cc(cnc2n2c(nnc2c1=O)C1(CC1)C1CC1)C(C)C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	972	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following phosphodiesterase activities are measured using [3H]cAMP as reaction substrate: human PDE3A (catalytic domain) and human PDE4D. Both en...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha/beta (Homo sapiens (Human))	BDBM528351 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-3- ethyl...) Show SMILES CCCCn1c2cc(CC)cnc2n2c(nnc2c1=O)C1(CC1)C1CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	982	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following phosphodiesterase activities are measured using [3H]cGMP as reaction substrate: human PDE6A/6B. The catalytic active form of human PDE6...				Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ
					More data for this Ligand-Target Pair

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