Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM562235 (1-([1,1′-bi(cyclopropan)]-1-yl)-5-(cyclobuty...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description All 3′, 5′ cyclic nucleotide phosphodiesterase (PDE) enzyme activities are measured with a radiometric enzyme assay based on SPA detectio... | Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528352 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-isopropy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.396 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528349 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-2,3- dim...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM50300099 (6-benzyl-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE1C expressed in Sf9 cells using [3H]cAMP as substrate after 30 mins by scintillation proximity assay | J Med Chem 55: 9045-54 (2012) Article DOI: 10.1021/jm3007799 BindingDB Entry DOI: 10.7270/Q24J0G79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528331 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-methylpy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.406 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528351 (9-([1,1'- Bi(cyclopropan)]-1- yl)-5-butyl-3- ethyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.419 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279100 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10512632 (2019) BindingDB Entry DOI: 10.7270/Q25T3NVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279100 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | 7.6 | 25 |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10034861 (2018) BindingDB Entry DOI: 10.7270/Q2X350HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279100 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q26977HV | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM580556 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2R78K2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM501501 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff... | US Patent US11026923 (2021) BindingDB Entry DOI: 10.7270/Q20R9SJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279100 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10806718 (2020) BindingDB Entry DOI: 10.7270/Q27P92FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279100 (5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme... | US Patent US10766893 (2020) BindingDB Entry DOI: 10.7270/Q2ZP495P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279101 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10806718 (2020) BindingDB Entry DOI: 10.7270/Q27P92FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM580557 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1- methylimida...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2R78K2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279101 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q26977HV | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279101 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | 7.6 | 25 |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10034861 (2018) BindingDB Entry DOI: 10.7270/Q2X350HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279101 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme... | US Patent US10766893 (2020) BindingDB Entry DOI: 10.7270/Q2ZP495P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279101 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylimidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10512632 (2019) BindingDB Entry DOI: 10.7270/Q25T3NVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM501502 (5-(2-ethoxy-3-pyridyl)-3-methyl-N-[1- methylimidaz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff... | US Patent US11026923 (2021) BindingDB Entry DOI: 10.7270/Q20R9SJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279111 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4-yl)met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.6 | 25 |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10034861 (2018) BindingDB Entry DOI: 10.7270/Q2X350HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM501512 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4- yl)me...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff... | US Patent US11026923 (2021) BindingDB Entry DOI: 10.7270/Q20R9SJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279111 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4-yl)met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2R78K2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279111 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4-yl)met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10806718 (2020) BindingDB Entry DOI: 10.7270/Q27P92FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279111 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4-yl)met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q26977HV | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279111 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4-yl)met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10512632 (2019) BindingDB Entry DOI: 10.7270/Q25T3NVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279111 (1-isopropyl-3-methyl-N-[(1-methylimidazol-4-yl)met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme... | US Patent US10766893 (2020) BindingDB Entry DOI: 10.7270/Q2ZP495P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM50540037 (CHEMBL4639341) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University Curated by ChEMBL | Assay Description Inhibition of PDE1C2 (147 to 531 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting method | J Med Chem 63: 7867-7879 (2020) Article DOI: 10.1021/acs.jmedchem.0c00711 BindingDB Entry DOI: 10.7270/Q20V8HBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528353 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-3-((2-(tri...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.928 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM573147 (US11453673, Example 9) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.958 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C... | Citation and Details BindingDB Entry DOI: 10.7270/Q22Z18RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM573138 (US11453673, Example 4) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 1.06 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C... | Citation and Details BindingDB Entry DOI: 10.7270/Q22Z18RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528355 (9-([1,1'-bi(cyclopropan)]-1-yl)-5-butyl-2-methylpy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme... | US Patent US10766893 (2020) BindingDB Entry DOI: 10.7270/Q2ZP495P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10512632 (2019) BindingDB Entry DOI: 10.7270/Q25T3NVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 7.6 | 25 |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10034861 (2018) BindingDB Entry DOI: 10.7270/Q2X350HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q26977HV | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2R78K2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10806718 (2020) BindingDB Entry DOI: 10.7270/Q27P92FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279114 (1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff... | US Patent US11026923 (2021) BindingDB Entry DOI: 10.7270/Q20R9SJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM573155 (US11453673, Example 16) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C... | Citation and Details BindingDB Entry DOI: 10.7270/Q22Z18RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM573136 (US11453673, Example 3) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C... | Citation and Details BindingDB Entry DOI: 10.7270/Q22Z18RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM580475 (3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2R78K2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279038 (3-methyl-1-[1-methylpropyl]-N-[(2-methyltetrazol-5...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q26977HV | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279038 (3-methyl-1-[1-methylpropyl]-N-[(2-methyltetrazol-5...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 7.6 | 25 |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10034861 (2018) BindingDB Entry DOI: 10.7270/Q2X350HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279038 (3-methyl-1-[1-methylpropyl]-N-[(2-methyltetrazol-5...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10512632 (2019) BindingDB Entry DOI: 10.7270/Q25T3NVN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279038 (3-methyl-1-[1-methylpropyl]-N-[(2-methyltetrazol-5...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme... | US Patent US10766893 (2020) BindingDB Entry DOI: 10.7270/Q2ZP495P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM279038 (3-methyl-1-[1-methylpropyl]-N-[(2-methyltetrazol-5...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ... | US Patent US10806718 (2020) BindingDB Entry DOI: 10.7270/Q27P92FR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM501437 (3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff... | US Patent US11026923 (2021) BindingDB Entry DOI: 10.7270/Q20R9SJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM573154 (US11453673, Example 15) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TABLE 5: All 3′, 5′ cyclic nucleotide PDE enzyme activities are measured with a radiometric enzyme assay based on SPA detection system. C... | Citation and Details BindingDB Entry DOI: 10.7270/Q22Z18RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM528334 (US11180503, Example 4 | US11180503, Example 4a | U...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description PDE1B, PDE1A, and PDE1C are cloned and purified following standard protein generation procedures. The assay buffer is prepared to give a final concen... | Citation and Details BindingDB Entry DOI: 10.7270/Q27947WZ | |||||||||||
More data for this Ligand-Target Pair |
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