Compile Data Set for Download or QSAR

Found 67 hits Enz. Inhib. hit(s) with all data for entry = 928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7322 (14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...) Show SMILES Oc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1 Show InChI InChI=1S/C16H11BrN2O2/c17-8-1-4-13-11(5-8)12-7-15(21)18-14-6-9(20)2-3-10(14)16(12)19-13/h1-6,19-20H,7H2,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7330 (2-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...) Show SMILES COc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)[N+]([O-])=O)-c2c1 Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-5-15-13(7-10)17-12(8-16(21)18-15)11-6-9(20(22)23)2-4-14(11)19-17/h2-7,19H,8H2,1H3,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7335 (5-(4-aminobutoxy)-14-bromo-8,18-diazatetracyclo[9....) Show SMILES NCCCCOc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1 Show InChI InChI=1S/C20H20BrN3O2/c21-12-3-6-17-15(9-12)16-11-19(25)23-18-10-13(26-8-2-1-7-22)4-5-14(18)20(16)24-17/h3-6,9-10,24H,1-2,7-8,11,22H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7340 (13-nitro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...) Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9N3O3S/c18-12-6-9-8-5-7(17(19)20)1-2-10(8)16-13(9)14-11(15-12)3-4-21-14/h1-5,16H,6H2,(H,15,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7330 (2-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...) Show SMILES COc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)[N+]([O-])=O)-c2c1 Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-5-15-13(7-10)17-12(8-16(21)18-15)11-6-9(20(22)23)2-4-14(11)19-17/h2-7,19H,8H2,1H3,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7329 (3-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)[N+]([O-])=O Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-4-11-15(7-10)18-16(21)8-13-12-6-9(20(22)23)2-5-14(12)19-17(11)13/h2-7,19H,8H2,1H3,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7339 (5-Oxo-4,5,6,11-tetrahydro-thieno[3 ,2 :2,3]azepino...) Show SMILES O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2sccc2N1 Show InChI InChI=1S/C15H9N3OS/c16-7-8-1-2-11-9(5-8)10-6-13(19)17-12-3-4-20-15(12)14(10)18-11/h1-5,18H,6H2,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7330 (2-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...) Show SMILES COc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)[N+]([O-])=O)-c2c1 Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-5-15-13(7-10)17-12(8-16(21)18-15)11-6-9(20(22)23)2-4-14(11)19-17/h2-7,19H,8H2,1H3,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7340 (13-nitro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...) Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9N3O3S/c18-12-6-9-8-5-7(17(19)20)1-2-10(8)16-13(9)14-11(15-12)3-4-21-14/h1-5,16H,6H2,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7325 (2-(2-oxopropyl)-9-(trifluoromethyl)-7,12-dihydroin...) Show SMILES CC(=O)Cc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2c1 Show InChI InChI=1S/C20H15F3N2O2/c1-10(26)6-11-2-4-17-15(7-11)19-14(9-18(27)24-17)13-8-12(20(21,22)23)3-5-16(13)25-19/h2-5,7-8,25H,6,9H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7340 (13-nitro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...) Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9N3O3S/c18-12-6-9-8-5-7(17(19)20)1-2-10(8)16-13(9)14-11(15-12)3-4-21-14/h1-5,16H,6H2,(H,15,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7336 (13-bromo-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...) Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9BrN2OS/c15-7-1-2-10-8(5-7)9-6-12(18)16-11-3-4-19-14(11)13(9)17-10/h1-5,17H,6H2,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7328 (3-Methoxy-6-oxo-5,6,7,12-tetrahydro-indolo[3,2-d][...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C#N Show InChI InChI=1S/C18H13N3O2/c1-23-11-3-4-12-16(7-11)20-17(22)8-14-13-6-10(9-19)2-5-15(13)21-18(12)14/h2-7,21H,8H2,1H3,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7325 (2-(2-oxopropyl)-9-(trifluoromethyl)-7,12-dihydroin...) Show SMILES CC(=O)Cc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2c1 Show InChI InChI=1S/C20H15F3N2O2/c1-10(26)6-11-2-4-17-15(7-11)19-14(9-18(27)24-17)13-8-12(20(21,22)23)3-5-16(13)25-19/h2-5,7-8,25H,6,9H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7320 (3-Methoxy-9-trifluormethyl-7,12-dihydro-indolo[3,2...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C18H13F3N2O2/c1-25-10-3-4-11-15(7-10)22-16(24)8-13-12-6-9(18(19,20)21)2-5-14(12)23-17(11)13/h2-7,23H,8H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7318 (14-bromo-4-iodo-8,18-diazatetracyclo[9.7.0.0^{2,7}...) Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccc(I)cc-34)c2c1 Show InChI InChI=1S/C16H10BrIN2O/c17-8-1-3-13-10(5-8)11-7-15(21)19-14-4-2-9(18)6-12(14)16(11)20-13/h1-6,20H,7H2,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7339 (5-Oxo-4,5,6,11-tetrahydro-thieno[3 ,2 :2,3]azepino...) Show SMILES O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2sccc2N1 Show InChI InChI=1S/C15H9N3OS/c16-7-8-1-2-11-9(5-8)10-6-13(19)17-12-3-4-20-15(12)14(10)18-11/h1-5,18H,6H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7339 (5-Oxo-4,5,6,11-tetrahydro-thieno[3 ,2 :2,3]azepino...) Show SMILES O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2sccc2N1 Show InChI InChI=1S/C15H9N3OS/c16-7-8-1-2-11-9(5-8)10-6-13(19)17-12-3-4-20-15(12)14(10)18-11/h1-5,18H,6H2,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7338 (13-chloro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6...) Show SMILES Clc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9ClN2OS/c15-7-1-2-10-8(5-7)9-6-12(18)16-11-3-4-19-14(11)13(9)17-10/h1-5,17H,6H2,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7325 (2-(2-oxopropyl)-9-(trifluoromethyl)-7,12-dihydroin...) Show SMILES CC(=O)Cc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)C(F)(F)F)-c2c1 Show InChI InChI=1S/C20H15F3N2O2/c1-10(26)6-11-2-4-17-15(7-11)19-14(9-18(27)24-17)13-8-12(20(21,22)23)3-5-16(13)25-19/h2-5,7-8,25H,6,9H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7338 (13-chloro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6...) Show SMILES Clc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9ClN2OS/c15-7-1-2-10-8(5-7)9-6-12(18)16-11-3-4-19-14(11)13(9)17-10/h1-5,17H,6H2,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7336 (13-bromo-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...) Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9BrN2OS/c15-7-1-2-10-8(5-7)9-6-12(18)16-11-3-4-19-14(11)13(9)17-10/h1-5,17H,6H2,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7333 (14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...) Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=S)Nc4ccccc-34)c2c1 Show InChI InChI=1S/C16H11N3O2S/c20-19(21)9-5-6-14-11(7-9)12-8-15(22)17-13-4-2-1-3-10(13)16(12)18-14/h1-7,18H,8H2,(H,17,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7322 (14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...) Show SMILES Oc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1 Show InChI InChI=1S/C16H11BrN2O2/c17-8-1-4-13-11(5-8)12-7-15(21)18-14-6-9(20)2-3-10(14)16(12)19-13/h1-6,19-20H,7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7329 (3-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)[N+]([O-])=O Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-4-11-15(7-10)18-16(21)8-13-12-6-9(20(22)23)2-5-14(12)19-17(11)13/h2-7,19H,8H2,1H3,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7320 (3-Methoxy-9-trifluormethyl-7,12-dihydro-indolo[3,2...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C18H13F3N2O2/c1-25-10-3-4-11-15(7-10)22-16(24)8-13-12-6-9(18(19,20)21)2-5-14(12)23-17(11)13/h2-7,23H,8H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7335 (5-(4-aminobutoxy)-14-bromo-8,18-diazatetracyclo[9....) Show SMILES NCCCCOc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1 Show InChI InChI=1S/C20H20BrN3O2/c21-12-3-6-17-15(9-12)16-11-19(25)23-18-10-13(26-8-2-1-7-22)4-5-14(18)20(16)24-17/h3-6,9-10,24H,1-2,7-8,11,22H2,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7322 (14-bromo-5-hydroxy-8,18-diazatetracyclo[9.7.0.0^{2...) Show SMILES Oc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1 Show InChI InChI=1S/C16H11BrN2O2/c17-8-1-4-13-11(5-8)12-7-15(21)18-14-6-9(20)2-3-10(14)16(12)19-13/h1-6,19-20H,7H2,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7329 (3-Methoxy-9-nitro-7,12-dihydro-indolo[3,2-d][1]ben...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)[N+]([O-])=O Show InChI InChI=1S/C17H13N3O4/c1-24-10-3-4-11-15(7-10)18-16(21)8-13-12-6-9(20(22)23)2-5-14(12)19-17(11)13/h2-7,19H,8H2,1H3,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7328 (3-Methoxy-6-oxo-5,6,7,12-tetrahydro-indolo[3,2-d][...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C#N Show InChI InChI=1S/C18H13N3O2/c1-23-11-3-4-12-16(7-11)20-17(22)8-14-13-6-10(9-19)2-5-15(13)21-18(12)14/h2-7,21H,8H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7328 (3-Methoxy-6-oxo-5,6,7,12-tetrahydro-indolo[3,2-d][...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C#N Show InChI InChI=1S/C18H13N3O2/c1-23-11-3-4-12-16(7-11)20-17(22)8-14-13-6-10(9-19)2-5-15(13)21-18(12)14/h2-7,21H,8H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7319 (6-Oxo-5,6,7,12-tetrahydro-indolo[3,2-d][1]benzazep...) Show SMILES O=C1Cc2c([nH]c3ccccc23)-c2cc(ccc2N1)C#N Show InChI InChI=1S/C17H11N3O/c18-9-10-5-6-15-13(7-10)17-12(8-16(21)19-15)11-3-1-2-4-14(11)20-17/h1-7,20H,8H2,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7323 (9-Acetamido-7,12-dihydro-indolo[3,2-d][1]benzazepi...) Show SMILES CC(=O)Nc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1 Show InChI InChI=1S/C18H15N3O2/c1-10(22)19-11-6-7-16-13(8-11)14-9-17(23)20-15-5-3-2-4-12(15)18(14)21-16/h2-8,21H,9H2,1H3,(H,19,22)(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7337 (13-methyl-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6...) Show SMILES Cc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C15H12N2OS/c1-8-2-3-11-9(6-8)10-7-13(18)16-12-4-5-19-15(12)14(10)17-11/h2-6,17H,7H2,1H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7333 (14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...) Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=S)Nc4ccccc-34)c2c1 Show InChI InChI=1S/C16H11N3O2S/c20-19(21)9-5-6-14-11(7-9)12-8-15(22)17-13-4-2-1-3-10(13)16(12)18-14/h1-7,18H,8H2,(H,17,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7333 (14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...) Show SMILES [O-][N+](=O)c1ccc2[nH]c-3c(CC(=S)Nc4ccccc-34)c2c1 Show InChI InChI=1S/C16H11N3O2S/c20-19(21)9-5-6-14-11(7-9)12-8-15(22)17-13-4-2-1-3-10(13)16(12)18-14/h1-7,18H,8H2,(H,17,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7320 (3-Methoxy-9-trifluormethyl-7,12-dihydro-indolo[3,2...) Show SMILES COc1ccc2-c3[nH]c4ccc(cc4c3CC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C18H13F3N2O2/c1-25-10-3-4-11-15(7-10)22-16(24)8-13-12-6-9(18(19,20)21)2-5-14(12)23-17(11)13/h2-7,23H,8H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7332 (7,12-Dihydro-pyrido[3 ,2 :4,5]pyrrolo[3,2-d][1]ben...) Show SMILES O=C1Cc2c([nH]c3ncccc23)-c2ccccc2N1 Show InChI InChI=1S/C15H11N3O/c19-13-8-11-9-5-3-7-16-15(9)18-14(11)10-4-1-2-6-12(10)17-13/h1-7H,8H2,(H,16,18)(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7332 (7,12-Dihydro-pyrido[3 ,2 :4,5]pyrrolo[3,2-d][1]ben...) Show SMILES O=C1Cc2c([nH]c3ncccc23)-c2ccccc2N1 Show InChI InChI=1S/C15H11N3O/c19-13-8-11-9-5-3-7-16-15(9)18-14(11)10-4-1-2-6-12(10)17-13/h1-7H,8H2,(H,16,18)(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7319 (6-Oxo-5,6,7,12-tetrahydro-indolo[3,2-d][1]benzazep...) Show SMILES O=C1Cc2c([nH]c3ccccc23)-c2cc(ccc2N1)C#N Show InChI InChI=1S/C17H11N3O/c18-9-10-5-6-15-13(7-10)17-12(8-16(21)19-15)11-3-1-2-4-14(11)20-17/h1-7,20H,8H2,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7336 (13-bromo-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...) Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9BrN2OS/c15-7-1-2-10-8(5-7)9-6-12(18)16-11-3-4-19-14(11)13(9)17-10/h1-5,17H,6H2,(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7337 (13-methyl-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6...) Show SMILES Cc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C15H12N2OS/c1-8-2-3-11-9(6-8)10-7-13(18)16-12-4-5-19-15(12)14(10)17-11/h2-6,17H,7H2,1H3,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7318 (14-bromo-4-iodo-8,18-diazatetracyclo[9.7.0.0^{2,7}...) Show SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccc(I)cc-34)c2c1 Show InChI InChI=1S/C16H10BrIN2O/c17-8-1-3-13-10(5-8)11-7-15(21)19-14-4-2-9(18)6-12(14)16(11)20-13/h1-6,20H,7H2,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7338 (13-chloro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6...) Show SMILES Clc1ccc2[nH]c-3c(CC(=O)Nc4ccsc-34)c2c1 Show InChI InChI=1S/C14H9ClN2OS/c15-7-1-2-10-8(5-7)9-6-12(18)16-11-3-4-19-14(11)13(9)17-10/h1-5,17H,6H2,(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7327 (14-(trifluoromethyl)-6,8,18-triazatetracyclo[9.7.0...) Show SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1 Show InChI InChI=1S/C16H10F3N3O/c17-16(18,19)8-3-4-12-10(6-8)11-7-13(23)22-15-9(14(11)21-12)2-1-5-20-15/h1-6,21H,7H2,(H,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7332 (7,12-Dihydro-pyrido[3 ,2 :4,5]pyrrolo[3,2-d][1]ben...) Show SMILES O=C1Cc2c([nH]c3ncccc23)-c2ccccc2N1 Show InChI InChI=1S/C15H11N3O/c19-13-8-11-9-5-3-7-16-15(9)18-14(11)10-4-1-2-6-12(10)17-13/h1-7H,8H2,(H,16,18)(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7323 (9-Acetamido-7,12-dihydro-indolo[3,2-d][1]benzazepi...) Show SMILES CC(=O)Nc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1 Show InChI InChI=1S/C18H15N3O2/c1-10(22)19-11-6-7-16-13(8-11)14-9-17(23)20-15-5-3-2-4-12(15)18(14)21-16/h2-8,21H,9H2,1H3,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7327 (14-(trifluoromethyl)-6,8,18-triazatetracyclo[9.7.0...) Show SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1 Show InChI InChI=1S/C16H10F3N3O/c17-16(18,19)8-3-4-12-10(6-8)11-7-13(23)22-15-9(14(11)21-12)2-1-5-20-15/h1-6,21H,7H2,(H,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	7.2	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7321 (14-amino-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...) Show SMILES Nc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1 Show InChI InChI=1S/C16H13N3O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8,17H2,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7327 (14-(trifluoromethyl)-6,8,18-triazatetracyclo[9.7.0...) Show SMILES FC(F)(F)c1ccc2[nH]c-3c(CC(=O)Nc4ncccc-34)c2c1 Show InChI InChI=1S/C16H10F3N3O/c17-16(18,19)8-3-4-12-10(6-8)11-7-13(23)22-15-9(14(11)21-12)2-1-5-20-15/h1-6,21H,7H2,(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	30
Universitat Hamburg					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 47: 22-36 (2004) Article DOI: 10.1021/jm0308904 BindingDB Entry DOI: 10.7270/Q28050TR
					More data for this Ligand-Target Pair

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