Compile Data Set for Download or QSAR

Found 140 hits Enz. Inhib. hit(s) with all data for entry = 10968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549950 (CHEMBL4751541 | US11505536, Example 66) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4F)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.169	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549954 (CHEMBL4791380 | US11505536, Example 11) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(F)cccc4Cl)c(=O)c3cc2F)C(C)C)c1=O |(16.55,-8.54,;15.93,-7.13,;14.4,-6.97,;13.63,-5.64,;14.25,-4.23,;15.78,-4.07,;12.12,-5.96,;11.96,-7.49,;10.63,-8.25,;9.3,-7.49,;7.97,-8.25,;6.63,-7.48,;5.29,-8.25,;5.3,-9.79,;3.97,-10.56,;3.97,-12.11,;5.31,-12.88,;2.64,-12.88,;1.3,-12.11,;1.3,-10.57,;2.63,-9.8,;2.63,-8.26,;6.64,-10.56,;6.64,-12.1,;7.96,-9.8,;9.29,-10.57,;10.63,-9.8,;11.96,-10.58,;6.63,-5.94,;7.96,-5.17,;5.3,-5.17,;13.37,-8.11,;13.69,-9.62,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.222	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581533 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(=C)C(F)(F)F)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.226	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581522 (2-(2-Chloro-3-methoxyphenyl)-6-(4-ethyl-3-(hydroxy...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cccc(OC)c4Cl)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549949 (CHEMBL4753279 | US11505536, Example 82) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cc(F)ccc4C)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.249	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581554 ((R)-6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)[C@@H](C)C(F)(F)F)c1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549951 (CHEMBL4745588 | US11505536, Example 52) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(F)cccc4Cl)c(=O)c3cc2F)C(C)=C)c1=O |(36.41,-17.81,;35.78,-16.4,;34.25,-16.24,;33.48,-14.91,;34.11,-13.5,;35.64,-13.34,;31.98,-15.23,;31.82,-16.76,;30.49,-17.53,;29.15,-16.76,;27.82,-17.52,;26.49,-16.75,;25.15,-17.53,;25.16,-19.06,;23.82,-19.83,;22.49,-19.07,;22.48,-17.53,;21.16,-19.84,;21.16,-21.39,;22.49,-22.16,;23.83,-21.38,;25.16,-22.15,;26.49,-19.83,;26.5,-21.37,;27.82,-19.07,;29.15,-19.84,;30.49,-19.08,;31.82,-19.85,;26.49,-15.21,;27.82,-14.44,;25.15,-14.44,;33.22,-17.39,;33.54,-18.89,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.265	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549952 (CHEMBL4752247 | US11505536, Example 51) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(F)ccc(OC)c4Cl)c(=O)c3cc2F)C(C)=C)c1=O |(18.24,-18.73,;17.61,-17.33,;16.08,-17.17,;15.31,-15.83,;15.94,-14.43,;17.47,-14.26,;13.81,-16.15,;13.65,-17.69,;12.32,-18.45,;10.99,-17.68,;9.65,-18.45,;8.32,-17.68,;6.98,-18.45,;6.99,-19.99,;5.66,-20.76,;4.32,-20,;4.32,-18.46,;2.99,-20.77,;2.99,-22.31,;4.32,-23.08,;4.33,-24.62,;5.66,-25.39,;5.66,-22.31,;7,-23.08,;8.33,-20.76,;8.33,-22.3,;9.65,-19.99,;10.98,-20.77,;12.32,-20,;13.65,-20.77,;8.32,-16.14,;9.65,-15.37,;6.98,-15.37,;15.05,-18.31,;15.37,-19.82,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.267	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581532 (2-(2-Chloro-6-fluoro-3-methoxyphenyl)-6-(4-ethyl-3...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(F)ccc(OC)c4Cl)c(=O)c3cc2F)C(C)C)c1=O |(7.77,3.2,;6.87,1.95,;5.33,2.12,;4.56,3.45,;5.19,4.86,;4.29,6.1,;3.06,3.13,;2.9,1.6,;1.56,.83,;.23,1.6,;-1.1,.83,;-2.44,1.6,;-3.77,.83,;-3.77,-.71,;-5.1,-1.48,;-6.44,-.71,;-6.44,.83,;-7.77,-1.48,;-7.77,-3.02,;-6.44,-3.79,;-6.44,-5.33,;-5.1,-6.1,;-5.1,-3.02,;-3.77,-3.79,;-2.44,-1.48,;-2.44,-3.02,;-1.1,-.71,;.23,-1.48,;1.56,-.71,;2.9,-1.48,;-2.44,3.14,;-3.77,3.91,;-1.1,3.91,;4.3,.97,;4.62,-.53,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.273	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581512 (2-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-6-(4-ethyl-3...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(C)n[nH]c4Cl)c(=O)c3cc2F)C(C)=C)c1=O |(7.66,2.17,;6.75,.93,;5.22,1.09,;4.45,2.42,;5.08,3.83,;4.17,5.07,;2.94,2.1,;2.78,.57,;1.45,-.2,;.12,.57,;-1.22,-.2,;-2.55,.57,;-3.89,-.2,;-3.89,-1.74,;-5.22,-2.51,;-6.63,-1.88,;-6.95,-.38,;-7.66,-3.03,;-6.89,-4.36,;-5.38,-4.04,;-4.24,-5.07,;-2.55,-2.51,;-2.55,-4.05,;-1.22,-1.74,;.12,-2.51,;1.45,-1.74,;2.78,-2.51,;-2.55,2.11,;-1.22,2.88,;-3.89,2.88,;4.19,-.06,;4.51,-1.56,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.286	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581539 (2-(2,5-Dimethylphenyl)-6-(4-ethyl-3-(hydroxymethyl...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cc(C)ccc4C)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.292	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581479 (2-(2-Chloro-6-fluorophenyl)-6-(4-ethyl-3-(hydroxym...) Show SMILES CCn1c(CO)nn(-c2cc3c(nn(-c4c(F)cccc4Cl)c(=O)c3cc2F)C(C)=C)c1=O |(7.7,2.21,;6.93,.88,;5.4,1.04,;4.63,2.37,;5.26,3.78,;4.17,4.87,;3.13,2.05,;2.97,.52,;1.63,-.25,;.3,.52,;-1.04,-.25,;-2.37,.52,;-3.7,-.25,;-3.7,-1.79,;-5.04,-2.56,;-5.04,-4.1,;-3.7,-4.87,;-6.37,-4.87,;-7.7,-4.1,;-7.7,-2.56,;-6.37,-1.79,;-6.37,-.25,;-2.37,-2.56,;-2.37,-4.1,;-1.04,-1.79,;.3,-2.56,;1.63,-1.79,;2.97,-2.56,;-2.37,2.06,;-3.7,2.83,;-1.04,2.83,;4.37,-.11,;4.69,-1.61,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581488 (6-(2-Chloro-6-fluorophenyl)-2-(4-ethyl-3-(hydroxym...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4c(F)cccc4Cl)c(=O)c3cc2F)C(C)C)c1=O |(7.77,2.05,;6.87,.8,;5.33,.96,;4.56,2.29,;5.19,3.7,;4.29,4.95,;3.06,1.97,;2.9,.44,;1.56,-.33,;.23,.44,;-1.1,-.33,;-2.44,.44,;-3.77,-.33,;-3.77,-1.87,;-5.1,-2.64,;-6.44,-1.87,;-6.44,-.33,;-7.77,-2.64,;-7.77,-4.18,;-6.44,-4.95,;-5.1,-4.18,;-3.77,-4.95,;-2.44,-2.64,;-2.44,-4.18,;-1.1,-1.87,;.23,-2.64,;1.56,-1.87,;2.9,-2.64,;-2.44,1.98,;-3.77,2.75,;-1.1,2.75,;4.3,-.18,;4.62,-1.69,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.356	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549953 (CHEMBL4751399 | US11505536, Example 93) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.396	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581569 (2-(2-Chlorophenyl)-6-(4-ethyl-3-(hydroxymethyl)-5-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4Cl)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.418	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581506 (2-(2-Chloro-6-fluorophenyl)-6-(4-ethyl-3-(hydroxym...) Show SMILES CCn1c(CO)nn(-c2cc3c(nn(-c4c(F)cccc4Cl)c(=O)c3cc2F)C(C)C)c1=O |(7.77,2.05,;6.87,.8,;5.33,.96,;4.56,2.29,;5.19,3.7,;4.29,4.95,;3.06,1.97,;2.9,.44,;1.56,-.33,;.23,.44,;-1.1,-.33,;-2.44,.44,;-3.77,-.33,;-3.77,-1.87,;-5.1,-2.64,;-5.1,-4.18,;-3.77,-4.95,;-6.44,-4.95,;-7.77,-4.18,;-7.77,-2.64,;-6.44,-1.87,;-6.44,-.33,;-2.44,-2.64,;-2.44,-4.18,;-1.1,-1.87,;.23,-2.64,;1.56,-1.87,;2.9,-2.64,;-2.44,1.98,;-3.77,2.75,;-1.1,2.75,;4.3,-.18,;4.62,-1.69,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.433	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581521 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(C)cccc4F)c(=O)c3cc2F)C(C)C)c1=O |(7.77,2.05,;6.87,.8,;5.33,.96,;4.56,2.29,;5.19,3.7,;4.29,4.95,;3.06,1.97,;2.9,.44,;1.56,-.33,;.23,.44,;-1.1,-.33,;-2.44,.44,;-3.77,-.33,;-3.77,-1.87,;-5.1,-2.64,;-5.1,-4.18,;-3.77,-4.95,;-6.44,-4.95,;-7.77,-4.18,;-7.77,-2.64,;-6.44,-1.87,;-6.44,-.33,;-2.44,-2.64,;-2.44,-4.18,;-1.1,-1.87,;.23,-2.64,;1.56,-1.87,;2.9,-2.64,;-2.44,1.98,;-3.77,2.75,;-1.1,2.75,;4.3,-.18,;4.62,-1.69,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.435	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581535 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4OC)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.444	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581516 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccc(F)cc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.459	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50549953 (CHEMBL4751399 | US11505536, Example 93) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.463	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581490 ((R)-2-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4ccccc4C)c(=O)c3cc2F)[C@@H](C)C(F)(F)F)c1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.464	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581540 (Racemic-6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dih...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)C(F)(F)F)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581557 (2-(2-(Difluoromethyl)phenyl)-6-(4-ethyl-3-(hydroxy...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C(F)F)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.528	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581525 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(C)cccc4F)c(=O)c3cc2F)C(C)=C)c1=O |(7.77,2.05,;6.87,.8,;5.33,.96,;4.56,2.29,;5.19,3.7,;4.29,4.95,;3.06,1.97,;2.9,.44,;1.56,-.33,;.23,.44,;-1.1,-.33,;-2.44,.44,;-3.77,-.33,;-3.77,-1.87,;-5.1,-2.64,;-5.1,-4.18,;-3.77,-4.95,;-6.44,-4.95,;-7.77,-4.18,;-7.77,-2.64,;-6.44,-1.87,;-6.44,-.33,;-2.44,-2.64,;-2.44,-4.18,;-1.1,-1.87,;.23,-2.64,;1.56,-1.87,;2.9,-2.64,;-2.44,1.98,;-1.1,2.75,;-3.77,2.75,;4.3,-.18,;4.62,-1.69,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.562	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581527 (2-(2,5-Dimethylphenyl)-6-(4-ethyl-3-(hydroxymethyl...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cc(C)ccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581519 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cc(F)ccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.605	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581513 (2-(3-Chloro-2-methoxy-5-methylpyridin-4-yl)-6-(4-e...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(C)cnc(OC)c4Cl)c(=O)c3cc2F)C(C)C)c1=O |(7.63,.55,;7.01,1.95,;5.47,2.12,;4.7,3.45,;5.33,4.86,;4.43,6.1,;3.2,3.13,;3.04,1.6,;1.7,.83,;.37,1.6,;-.96,.83,;-2.3,1.6,;-3.63,.83,;-3.63,-.71,;-4.96,-1.48,;-6.3,-.71,;-6.3,.83,;-7.63,-1.48,;-7.63,-3.02,;-6.3,-3.79,;-6.3,-5.33,;-4.96,-6.1,;-4.96,-3.02,;-3.63,-3.79,;-2.3,-1.48,;-2.3,-3.02,;-.96,-.71,;.37,-1.48,;1.7,-.71,;3.04,-1.48,;-2.3,3.14,;-3.63,3.91,;-.96,3.91,;4.44,.97,;4.76,-.53,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.617	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581492 (2-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.623	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581467 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2ccc3c(c2)c(cn(-c2ccccc2C)c3=O)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.634	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581555 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C(F)(F)F)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.669	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581466 (2-(2-Chlorophenyl)-6-(4-ethyl-3-(hydroxymethyl)-5-...) Show SMILES CCn1c(CO)nn(-c2ccc3c(c2)c(cn(-c2ccccc2Cl)c3=O)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.724	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581498 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.746	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581483 (2-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-6-(4-ethyl-3...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(C)n[nH]c4Cl)c(=O)c3cc2F)C(C)C)c1=O |(7.59,2.34,;6.82,1,;5.29,1.17,;4.52,2.5,;5.14,3.91,;4.05,4.99,;3.01,2.18,;2.85,.65,;1.52,-.12,;.18,.65,;-1.15,-.12,;-2.48,.65,;-3.82,-.12,;-3.82,-1.66,;-5.15,-2.43,;-6.57,-1.77,;-6.89,-.26,;-7.59,-2.95,;-6.82,-4.28,;-5.31,-3.96,;-4.17,-4.99,;-2.48,-2.43,;-2.48,-3.97,;-1.15,-1.66,;.18,-2.43,;1.52,-1.66,;2.85,-2.43,;-2.48,2.19,;-1.15,2.96,;-3.82,2.96,;4.26,.02,;4.58,-1.49,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.764	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581547 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4OC)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.772	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581505 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(nn(-c4ccccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.778	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581492 (2-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.802	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581514 (2-(3-Chloro-2-methoxy-5-methylpyridin-4-yl)-6-(4-e...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4c(C)cnc(OC)c4Cl)c(=O)c3cc2F)C(C)=C)c1=O |(7.77,3.2,;6.87,1.95,;5.33,2.12,;4.56,3.45,;5.19,4.86,;4.29,6.1,;3.06,3.13,;2.9,1.6,;1.56,.83,;.23,1.6,;-1.1,.83,;-2.44,1.6,;-3.77,.83,;-3.77,-.71,;-5.1,-1.48,;-6.44,-.71,;-6.44,.83,;-7.77,-1.48,;-7.77,-3.02,;-6.44,-3.79,;-6.44,-5.33,;-5.1,-6.1,;-5.1,-3.02,;-3.77,-3.79,;-2.44,-1.48,;-2.44,-3.02,;-1.1,-.71,;.23,-1.48,;1.56,-.71,;2.9,-1.48,;-2.44,3.14,;-1.1,3.91,;-3.77,3.91,;4.3,.97,;4.62,-.53,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.836	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581460 (2-(2,6-Dichlorophenyl)-6-(4-ethyl-3-(hydroxymethyl...) Show SMILES CCn1c(CO)nn(-c2ccc3c(c2)c(cn(-c2c(Cl)cccc2Cl)c3=O)C(C)=C)c1=O |(7.67,-.16,;6.9,1.17,;5.36,1.17,;4.46,2.41,;4.86,3.9,;3.77,4.99,;2.99,1.94,;2.99,.4,;1.66,-.37,;1.66,-1.91,;.33,-2.68,;-1.01,-1.91,;-1.01,-.37,;.33,.4,;-2.34,.4,;-3.67,-.37,;-3.67,-1.91,;-5.01,-2.68,;-6.34,-1.91,;-6.34,-.37,;-7.67,-2.68,;-7.67,-4.22,;-6.34,-4.99,;-5.01,-4.22,;-3.67,-4.99,;-2.34,-2.68,;-2.34,-4.22,;-2.34,1.94,;-3.67,2.71,;-1.01,2.71,;4.46,-.08,;4.94,-1.54,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.839	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581582 (2-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4ccccc4OC)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.885	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581500 (US11505536, Example 48 | racemic-4-(sec-Butyl)-2-(...) Show SMILES CCC(C)c1cn(-c2c(F)cccc2Cl)c(=O)c2cc(F)c(cc12)-n1nc(CO)n(CC)c1=O |(-.95,4.29,;-.95,2.75,;-2.29,1.98,;-3.62,2.75,;-2.29,.44,;-3.62,-.33,;-3.62,-1.87,;-4.95,-2.64,;-4.95,-4.18,;-3.62,-4.95,;-6.29,-4.95,;-7.62,-4.18,;-7.62,-2.64,;-6.29,-1.87,;-6.29,-.33,;-2.29,-2.64,;-2.29,-4.18,;-.95,-1.87,;.38,-2.64,;1.71,-1.87,;3.05,-2.64,;1.71,-.33,;.38,.44,;-.95,-.33,;3.05,.44,;3.21,1.97,;4.71,2.29,;5.34,3.7,;4.44,4.95,;5.48,.96,;7.02,.8,;7.62,-.62,;4.45,-.18,;4.77,-1.69,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.907	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581495 (2-(2-Chloro-5-methylphenyl)-6-(4-ethyl-3-(hydroxym...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cc(C)ccc4Cl)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.917	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581524 (2-(2,5-Difluorophenyl)-6-(4-ethyl-3-(hydroxymethyl...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cc(F)ccc4F)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.946	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581459 (2-(2,6-Dichlorophenyl)-6-(4-ethyl-3-(hydroxymethyl...) Show SMILES CCn1c(CO)nn(-c2ccc3c(c2)c(cn(-c2c(Cl)cccc2Cl)c3=O)C2(C)CC2)c1=O |(7.67,-.16,;6.9,1.17,;5.36,1.17,;4.46,2.41,;4.86,3.9,;3.77,4.99,;2.99,1.94,;2.99,.4,;1.66,-.37,;1.66,-1.91,;.33,-2.68,;-1.01,-1.91,;-1.01,-.37,;.33,.4,;-2.34,.4,;-3.67,-.37,;-3.67,-1.91,;-5.01,-2.68,;-6.34,-1.91,;-6.34,-.37,;-7.67,-2.68,;-7.67,-4.22,;-6.34,-4.99,;-5.01,-4.22,;-3.67,-4.99,;-2.34,-2.68,;-2.34,-4.22,;-2.34,1.94,;-3.67,2.71,;-1.01,2.71,;-2.34,3.48,;4.46,-.08,;4.94,-1.54,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.965	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581484 (2-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4ccccc4C)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581501 (2-(3-Chloro-6-methoxypyridin-2-yl)-6-(4-ethyl-3-(h...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4nc(OC)ccc4Cl)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.09	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581590 (6-(2-(Difluoromethyl)phenyl)-2-(4-ethyl-3-(hydroxy...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4ccccc4C(F)F)c(=O)c3cc2F)C(C)C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581487 (6-(2-Chloro-6-fluorophenyl)-2-(4-ethyl-3-(hydroxym...) Show SMILES CCn1c(CO)nn(-c2nc3c(cn(-c4c(F)cccc4Cl)c(=O)c3cc2F)C(C)=C)c1=O |(7.77,2.05,;6.87,.8,;5.33,.96,;4.56,2.29,;5.19,3.7,;4.29,4.95,;3.06,1.97,;2.9,.44,;1.56,-.33,;.23,.44,;-1.1,-.33,;-2.44,.44,;-3.77,-.33,;-3.77,-1.87,;-5.1,-2.64,;-6.44,-1.87,;-6.44,-.33,;-7.77,-2.64,;-7.77,-4.18,;-6.44,-4.95,;-5.1,-4.18,;-3.77,-4.95,;-2.44,-2.64,;-2.44,-4.18,;-1.1,-1.87,;.23,-2.64,;1.56,-1.87,;2.9,-2.64,;-2.44,1.98,;-1.1,2.75,;-3.77,2.75,;4.3,-.18,;4.62,-1.69,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581509 ((R*)-6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydr...) Show SMILES CCn1c(CO)nn(-c2cc3c(nn(-c4ccccc4C)c(=O)c3cc2F)[C@@H](C)C(F)(F)F)c1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581538 (6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4cccc(F)c4C)c(=O)c3cc2F)C(C)=C)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM581553 ((S)-6-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro...) Show SMILES CCn1c(CO)nn(-c2cc3c(cn(-c4ccccc4C)c(=O)c3cc2F)[C@H](C)C(F)(F)F)c1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following assay is referred to herein as the DHODH Enzymatic Assay. To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8Z24
					More data for this Ligand-Target Pair

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