Found 44 hits Enz. Inhib. hit(s) with all data for entry = 6418 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20557
(AMG 517 | CHEMBL229430 | JMC503515 Compound 23 | N...)Show SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)cccc2s1 Show InChI InChI=1S/C20H13F3N4O2S/c1-11(28)26-19-27-18-15(3-2-4-16(18)30-19)29-17-9-14(24-10-25-17)12-5-7-13(8-6-12)20(21,22)23/h2-10H,1H3,(H,26,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128023
(US8796328, C)Show SMILES CC(C)(C)c1ccc2[C@@H](CCc2c1)NC(=O)Nc1cccc2scnc12 |r| Show InChI InChI=1S/C21H23N3OS/c1-21(2,3)14-8-9-15-13(11-14)7-10-16(15)23-20(25)24-17-5-4-6-18-19(17)22-12-26-18/h4-6,8-9,11-12,16H,7,10H2,1-3H3,(H2,23,24,25)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128033
(US8796328, 10)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3cc(ccc23)C(F)(F)F)cc1F Show InChI InChI=1S/C21H21F6N3O4S/c1-35(32,33)30-16-5-2-12(6-15(16)24)9-28-19(31)29-17-8-20(10-22,11-23)34-18-7-13(21(25,26)27)3-4-14(17)18/h2-7,17,30H,8-11H2,1H3,(H2,28,29,31)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128022
(US8796328, B | US8802711, I)Show SMILES CC(C)(C)c1ccc(Nc2ncnc3cc(ccc23)-c2ncccc2C(F)(F)F)cc1 Show InChI InChI=1S/C24H21F3N4/c1-23(2,3)16-7-9-17(10-8-16)31-22-18-11-6-15(13-20(18)29-14-30-22)21-19(24(25,26)27)5-4-12-28-21/h4-14H,1-3H3,(H,29,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50264258
(1-(3-Methylpyridin-2-yl)-N-(4-(trifluoromethylsulf...)Show SMILES Cc1cccnc1N1CCC(=CC1)C(=O)Nc1ccc(cc1)S(=O)(=O)C(F)(F)F |c:11| Show InChI InChI=1S/C19H18F3N3O3S/c1-13-3-2-10-23-17(13)25-11-8-14(9-12-25)18(26)24-15-4-6-16(7-5-15)29(27,28)19(20,21)22/h2-8,10H,9,11-12H2,1H3,(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128024
(US8796328, 1)Show SMILES CC(C)(C)c1ccc2[C@@H](CCc2c1)NC(=O)NCc1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C22H28FN3O3S/c1-22(2,3)16-7-8-17-15(12-16)6-10-19(17)25-21(27)24-13-14-5-9-20(18(23)11-14)26-30(4,28)29/h5,7-9,11-12,19,26H,6,10,13H2,1-4H3,(H2,24,25,27)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128032
(US8796328, 9)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(cc2O1)C(F)(F)F Show InChI InChI=1S/C21H23F4N3O4S/c1-20(2)10-17(14-6-5-13(21(23,24)25)9-18(14)32-20)27-19(29)26-11-12-4-7-16(15(22)8-12)28-33(3,30)31/h4-9,17,28H,10-11H2,1-3H3,(H2,26,27,29)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50321851
((R)-8-{5-[3-Methyl-4-(trifluoromethyl)phenyl]oxazo...)Show SMILES Cc1nc(Nc2cccc3CC[C@@H](O)Cc23)oc1-c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H19F3N2O2/c1-12-19(14-5-8-15(9-6-14)21(22,23)24)28-20(25-12)26-18-4-2-3-13-7-10-16(27)11-17(13)18/h2-6,8-9,16,27H,7,10-11H2,1H3,(H,25,26)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128037
(US8796328, 14)Show SMILES CCC1(CC)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(Cl)cc2O1 Show InChI InChI=1S/C22H27ClFN3O4S/c1-4-22(5-2)12-19(16-8-7-15(23)11-20(16)31-22)26-21(28)25-13-14-6-9-18(17(24)10-14)27-32(3,29)30/h6-11,19,27H,4-5,12-13H2,1-3H3,(H2,25,26,28)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128057
(US8796328, 37)Show SMILES C[C@@]1(CF)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(cc2O1)C(F)(F)F Show InChI InChI=1S/C21H22F5N3O4S/c1-20(11-22)9-17(14-5-4-13(21(24,25)26)8-18(14)33-20)28-19(30)27-10-12-3-6-16(15(23)7-12)29-34(2,31)32/h3-8,17,29H,9-11H2,1-2H3,(H2,27,28,30)/t17-,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 256 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128028
(US8796328, 5)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCc3cc(ccc23)C(F)(F)F)cc1F Show InChI InChI=1S/C19H19F4N3O3S/c1-30(28,29)26-17-6-2-11(8-15(17)20)10-24-18(27)25-16-7-3-12-9-13(19(21,22)23)4-5-14(12)16/h2,4-6,8-9,16,26H,3,7,10H2,1H3,(H2,24,25,27)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128031
(US8796328, 8)Show SMILES CCC1(CC)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(Cl)c(Cl)c2O1 Show InChI InChI=1S/C22H26Cl2FN3O4S/c1-4-22(5-2)11-18(14-7-8-15(23)19(24)20(14)32-22)27-21(29)26-12-13-6-9-17(16(25)10-13)28-33(3,30)31/h6-10,18,28H,4-5,11-12H2,1-3H3,(H2,26,27,29)/t18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128058
(US8796328, 38)Show SMILES C[C@]1(CF)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(cc2O1)C(F)(F)F Show InChI InChI=1S/C21H22F5N3O4S/c1-20(11-22)9-17(14-5-4-13(21(24,25)26)8-18(14)33-20)28-19(30)27-10-12-3-6-16(15(23)7-12)29-34(2,31)32/h3-8,17,29H,9-11H2,1-2H3,(H2,27,28,30)/t17-,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 345 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128046
(US8796328, 23)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(F)c(Cl)c2O1 Show InChI InChI=1S/C20H22ClF2N3O4S/c1-20(2)9-16(12-5-6-13(22)17(21)18(12)30-20)25-19(27)24-10-11-4-7-15(14(23)8-11)26-31(3,28)29/h4-8,16,26H,9-10H2,1-3H3,(H2,24,25,27)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 358 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128036
(US8796328, 13)Show SMILES CCC1(CC)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2cccc(F)c2O1 Show InChI InChI=1S/C22H27F2N3O4S/c1-4-22(5-2)12-19(15-7-6-8-16(23)20(15)31-22)26-21(28)25-13-14-9-10-18(17(24)11-14)27-32(3,29)30/h6-11,19,27H,4-5,12-13H2,1-3H3,(H2,25,26,28)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 418 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128042
(US8796328, 19)Show SMILES CCC1(CC)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(OC(F)(F)F)cc2O1 Show InChI InChI=1S/C23H27F4N3O5S/c1-4-22(5-2)12-19(16-8-7-15(11-20(16)35-22)34-23(25,26)27)29-21(31)28-13-14-6-9-18(17(24)10-14)30-36(3,32)33/h6-11,19,30H,4-5,12-13H2,1-3H3,(H2,28,29,31)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 466 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128056
(US8796328, 36)Show SMILES C[C@@]1(C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccccc2O1)C(F)(F)F Show InChI InChI=1S/C20H21F4N3O4S/c1-19(20(22,23)24)10-16(13-5-3-4-6-17(13)31-19)26-18(28)25-11-12-7-8-15(14(21)9-12)27-32(2,29)30/h3-9,16,27H,10-11H2,1-2H3,(H2,25,26,28)/t16-,19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128047
(US8796328, 25)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(Cl)cc2O1 Show InChI InChI=1S/C20H23ClFN3O4S/c1-20(2)10-17(14-6-5-13(21)9-18(14)29-20)24-19(26)23-11-12-4-7-16(15(22)8-12)25-30(3,27)28/h4-9,17,25H,10-11H2,1-3H3,(H2,23,24,26)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 602 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128059
(US8796328, 39)Show SMILES C[C@@]1(CF)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(Cl)cc2O1 Show InChI InChI=1S/C20H22ClF2N3O4S/c1-20(11-22)9-17(14-5-4-13(21)8-18(14)30-20)25-19(27)24-10-12-3-6-16(15(23)7-12)26-31(2,28)29/h3-8,17,26H,9-11H2,1-2H3,(H2,24,25,27)/t17-,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 615 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128030
(US8796328, 7)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(F)cc2O1 Show InChI InChI=1S/C20H23F2N3O4S/c1-20(2)10-17(14-6-5-13(21)9-18(14)29-20)24-19(26)23-11-12-4-7-16(15(22)8-12)25-30(3,27)28/h4-9,17,25H,10-11H2,1-3H3,(H2,23,24,26)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 747 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128043
(US8796328, 20)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3c(F)c(Cl)ccc23)cc1F Show InChI InChI=1S/C20H20ClF4N3O4S/c1-33(30,31)28-15-5-2-11(6-14(15)24)8-26-19(29)27-16-7-20(9-22,10-23)32-18-12(16)3-4-13(21)17(18)25/h2-6,16,28H,7-10H2,1H3,(H2,26,27,29)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 791 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128038
(US8796328, 15)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3cc(OC(F)(F)F)ccc23)cc1F Show InChI InChI=1S/C21H21F6N3O5S/c1-36(32,33)30-16-5-2-12(6-15(16)24)9-28-19(31)29-17-8-20(10-22,11-23)35-18-7-13(3-4-14(17)18)34-21(25,26)27/h2-7,17,30H,8-11H2,1H3,(H2,28,29,31)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 863 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128054
(US8796328, 32)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCOc3cc(ccc23)C(F)(F)F)cc1F Show InChI InChI=1S/C19H19F4N3O4S/c1-31(28,29)26-16-5-2-11(8-14(16)20)10-24-18(27)25-15-6-7-30-17-9-12(19(21,22)23)3-4-13(15)17/h2-5,8-9,15,26H,6-7,10H2,1H3,(H2,24,25,27)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 913 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128051
(US8796328, 29)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(F)c(F)c2O1 Show InChI InChI=1S/C20H22F3N3O4S/c1-20(2)9-16(12-5-6-13(21)17(23)18(12)30-20)25-19(27)24-10-11-4-7-15(14(22)8-11)26-31(3,28)29/h4-8,16,26H,9-10H2,1-3H3,(H2,24,25,27)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128064
(US8796328, 44)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)NC2CC3(CCCC3)Oc3ccccc23)cc1F Show InChI InChI=1S/C22H26FN3O4S/c1-31(28,29)26-18-9-8-15(12-17(18)23)14-24-21(27)25-19-13-22(10-4-5-11-22)30-20-7-3-2-6-16(19)20/h2-3,6-9,12,19,26H,4-5,10-11,13-14H2,1H3,(H2,24,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128026
(US8796328, 3)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCc3cc(Cl)ccc23)cc1F Show InChI InChI=1S/C18H19ClFN3O3S/c1-27(25,26)23-17-6-2-11(8-15(17)20)10-21-18(24)22-16-7-3-12-9-13(19)4-5-14(12)16/h2,4-6,8-9,16,23H,3,7,10H2,1H3,(H2,21,22,24)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128041
(US8796328, 18)Show SMILES CCC1(CC)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2cc(F)ccc2O1 Show InChI InChI=1S/C22H27F2N3O4S/c1-4-22(5-2)12-19(16-11-15(23)7-9-20(16)31-22)26-21(28)25-13-14-6-8-18(17(24)10-14)27-32(3,29)30/h6-11,19,27H,4-5,12-13H2,1-3H3,(H2,25,26,28)/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128055
(US8796328, 35)Show SMILES C[C@]1(C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccccc2O1)C(F)(F)F Show InChI InChI=1S/C20H21F4N3O4S/c1-19(20(22,23)24)10-16(13-5-3-4-6-17(13)31-19)26-18(28)25-11-12-7-8-15(14(21)9-12)27-32(2,29)30/h3-9,16,27H,10-11H2,1-2H3,(H2,25,26,28)/t16-,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128029
(US8796328, 6)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3cc(Cl)ccc23)cc1F Show InChI InChI=1S/C20H21ClF3N3O4S/c1-32(29,30)27-16-5-2-12(6-15(16)24)9-25-19(28)26-17-8-20(10-22,11-23)31-18-7-13(21)3-4-14(17)18/h2-7,17,27H,8-11H2,1H3,(H2,25,26,28)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128040
(US8796328, 17)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC3(CCC3)Oc3ccc(F)cc23)cc1F Show InChI InChI=1S/C21H23F2N3O4S/c1-31(28,29)26-17-5-3-13(9-16(17)23)12-24-20(27)25-18-11-21(7-2-8-21)30-19-6-4-14(22)10-15(18)19/h3-6,9-10,18,26H,2,7-8,11-12H2,1H3,(H2,24,25,27)/t18-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128053
(US8796328, 31)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCOc3c2cccc3C(F)(F)F)cc1F Show InChI InChI=1S/C19H19F4N3O4S/c1-31(28,29)26-16-6-5-11(9-14(16)20)10-24-18(27)25-15-7-8-30-17-12(15)3-2-4-13(17)19(21,22)23/h2-6,9,15,26H,7-8,10H2,1H3,(H2,24,25,27)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128061
(US8796328, 41)Show SMILES C[C@@]1(C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccccc2O1)C(F)F Show InChI InChI=1S/C20H22F3N3O4S/c1-20(18(22)23)10-16(13-5-3-4-6-17(13)30-20)25-19(27)24-11-12-7-8-15(14(21)9-12)26-31(2,28)29/h3-9,16,18,26H,10-11H2,1-2H3,(H2,24,25,27)/t16-,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 5.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128063
(US8796328, 43)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3cc(F)ccc23)cc1F Show InChI InChI=1S/C20H21F4N3O4S/c1-32(29,30)27-16-5-2-12(6-15(16)24)9-25-19(28)26-17-8-20(10-21,11-22)31-18-7-13(23)3-4-14(17)18/h2-7,17,27H,8-11H2,1H3,(H2,25,26,28)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 6.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128044
(US8796328, 21)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccccc2O1 Show InChI InChI=1S/C20H24FN3O4S/c1-20(2)11-17(14-6-4-5-7-18(14)28-20)23-19(25)22-12-13-8-9-16(15(21)10-13)24-29(3,26)27/h4-10,17,24H,11-12H2,1-3H3,(H2,22,23,25)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128045
(US8796328, 22)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2cc(F)ccc2O1 Show InChI InChI=1S/C20H23F2N3O4S/c1-20(2)10-17(14-9-13(21)5-7-18(14)29-20)24-19(26)23-11-12-4-6-16(15(22)8-12)25-30(3,27)28/h4-9,17,25H,10-11H2,1-3H3,(H2,23,24,26)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128060
(US8796328, 40)Show SMILES C[C@]1(C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccccc2O1)C(F)F Show InChI InChI=1S/C20H22F3N3O4S/c1-20(18(22)23)10-16(13-5-3-4-6-17(13)30-20)25-19(27)24-11-12-7-8-15(14(21)9-12)26-31(2,28)29/h3-9,16,18,26H,10-11H2,1-2H3,(H2,24,25,27)/t16-,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128027
(US8796328, 4)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCc3cc(F)ccc23)cc1F Show InChI InChI=1S/C18H19F2N3O3S/c1-27(25,26)23-17-6-2-11(8-15(17)20)10-21-18(24)22-16-7-3-12-9-13(19)4-5-14(12)16/h2,4-6,8-9,16,23H,3,7,10H2,1H3,(H2,21,22,24)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128049
(US8796328, 27)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3ccccc23)cc1F Show InChI InChI=1S/C20H22F3N3O4S/c1-31(28,29)26-16-7-6-13(8-15(16)23)10-24-19(27)25-17-9-20(11-21,12-22)30-18-5-3-2-4-14(17)18/h2-8,17,26H,9-12H2,1H3,(H2,24,25,27)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128039
(US8796328, 16)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3c(F)cc(F)cc23)cc1F Show InChI InChI=1S/C20H20F5N3O4S/c1-33(30,31)28-16-3-2-11(4-14(16)24)8-26-19(29)27-17-7-20(9-21,10-22)32-18-13(17)5-12(23)6-15(18)25/h2-6,17,28H,7-10H2,1H3,(H2,26,27,29)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128050
(US8796328, 28)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CC(CF)(CF)Oc3c(F)cccc23)cc1F Show InChI InChI=1S/C20H21F4N3O4S/c1-32(29,30)27-16-6-5-12(7-15(16)24)9-25-19(28)26-17-8-20(10-21,11-22)31-18-13(17)3-2-4-14(18)23/h2-7,17,27H,8-11H2,1H3,(H2,25,26,28)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128062
(US8796328, 42)Show SMILES CC1(C)C[C@@H](NC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(nc2O1)C(F)(F)F Show InChI InChI=1S/C20H22F4N4O4S/c1-19(2)9-15(12-5-7-16(20(22,23)24)27-17(12)32-19)26-18(29)25-10-11-4-6-14(13(21)8-11)28-33(3,30)31/h4-8,15,28H,9-10H2,1-3H3,(H2,25,26,29)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128052
(US8796328, 30)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCOc3ccc(F)cc23)cc1F Show InChI InChI=1S/C18H19F2N3O4S/c1-28(25,26)23-16-4-2-11(8-14(16)20)10-21-18(24)22-15-6-7-27-17-5-3-12(19)9-13(15)17/h2-5,8-9,15,23H,6-7,10H2,1H3,(H2,21,22,24)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >3.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128048
(US8796328, 26)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCOc3cc(OC(F)(F)F)ccc23)cc1F Show InChI InChI=1S/C19H19F4N3O5S/c1-32(28,29)26-16-5-2-11(8-14(16)20)10-24-18(27)25-15-6-7-30-17-9-12(3-4-13(15)17)31-19(21,22)23/h2-5,8-9,15,26H,6-7,10H2,1H3,(H2,24,25,27)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >3.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM128035
(US8796328, 12)Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)N[C@@H]2CCOc3ccccc23)cc1F Show InChI InChI=1S/C18H20FN3O4S/c1-27(24,25)22-16-7-6-12(10-14(16)19)11-20-18(23)21-15-8-9-26-17-5-3-2-4-13(15)17/h2-7,10,15,22H,8-9,11H2,1H3,(H2,20,21,23)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >3.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2]i) using the Fluorescence... |
US Patent US8796328 (2014)
BindingDB Entry DOI: 10.7270/Q2639NFM |
More data for this
Ligand-Target Pair | |
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