Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-activated protein kinase 2 (Homo sapiens (Human)) | BDBM175242 (US11844801, Compound (M)-I | US9115089, 49) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | 7.5 | n/a |
CONFLUENCE LIFE SCIENCES, INC. US Patent | Assay Description The ability of compounds to inhibit activated phospho-p38alpha is evaluated using a p38alpha /MK2 and a p38alpha /PRAK cascade assay format. The kina... | US Patent US9115089 (2015) BindingDB Entry DOI: 10.7270/Q25M64H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-activated protein kinase 5 (Homo sapiens (Human)) | BDBM175242 (US11844801, Compound (M)-I | US9115089, 49) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
CONFLUENCE LIFE SCIENCES, INC. US Patent | Assay Description The ability of compounds to inhibit activated phospho-p38alpha is evaluated using a p38alpha /MK2 and a p38alpha /PRAK cascade assay format. The kina... | US Patent US9115089 (2015) BindingDB Entry DOI: 10.7270/Q25M64H1 | |||||||||||
More data for this Ligand-Target Pair |