Compile Data Set for Download or QSAR

Found 160 hits Enz. Inhib. hit(s) with all data for entry = 8508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254745 (US9475775, 12 | US9597333, 12) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncn1C |t:9,18| Show InChI InChI=1S/C22H28N6O2/c1-4-8-28(9-5-2)22(30)17-10-15-6-7-16(11-18(15)25-19(23)12-17)21(29)26-20-13-24-14-27(20)3/h6-7,10-11,13-14H,4-5,8-9,12H2,1-3H3,(H2,23,25)(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254746 (US9475775, 13 | US9597333, 13) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(F)cc1 |t:9,18| Show InChI InChI=1S/C24H27FN4O2/c1-3-11-29(12-4-2)24(31)18-13-16-5-6-17(14-21(16)28-22(26)15-18)23(30)27-20-9-7-19(25)8-10-20/h5-10,13-14H,3-4,11-12,15H2,1-2H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254747 (US9475775, 14 | US9597333, 14) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:9,18| Show InChI InChI=1S/C25H30N4O2/c1-4-11-29(12-5-2)25(31)20-14-18-9-10-19(15-22(18)28-23(26)16-20)24(30)27-21-8-6-7-17(3)13-21/h6-10,13-15H,4-5,11-12,16H2,1-3H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254748 (US9475775, 15 | US9597333, 15) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(c1)C(=O)N1CCCC1 |t:9,18| Show InChI InChI=1S/C29H35N5O3/c1-3-12-33(13-4-2)29(37)23-16-20-10-11-21(18-25(20)32-26(30)19-23)27(35)31-24-9-7-8-22(17-24)28(36)34-14-5-6-15-34/h7-11,16-18H,3-6,12-15,19H2,1-2H3,(H2,30,32)(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254749 (US9475775, 16 | US9597333, 16) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(c1)C(=O)N1CCCC1 |t:9,18| Show InChI InChI=1S/C28H34N6O3/c1-3-9-33(10-4-2)27(36)21-13-19-7-8-20(15-24(19)32-25(29)16-21)26(35)31-23-14-22(17-30-18-23)28(37)34-11-5-6-12-34/h7-8,13-15,17-18H,3-6,9-12,16H2,1-2H3,(H2,29,32)(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254750 (US9475775, 17 | US9475775, 54 | US9597333, 54) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCN)c1 |t:9,18| Show InChI InChI=1S/C26H33N5O2/c1-3-12-31(13-4-2)26(33)21-15-19-8-9-20(16-23(19)30-24(28)17-21)25(32)29-22-7-5-6-18(14-22)10-11-27/h5-9,14-16H,3-4,10-13,17,27H2,1-2H3,(H2,28,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254751 (US9475775, 18 | US9597333, 18) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(C)c1 |t:9,18| Show InChI InChI=1S/C24H29N5O2/c1-4-8-29(9-5-2)24(31)19-11-17-6-7-18(12-21(17)28-22(25)13-19)23(30)27-20-10-16(3)14-26-15-20/h6-7,10-12,14-15H,4-5,8-9,13H2,1-3H3,(H2,25,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254752 (US9475775, 19 | US9597333, 19) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(F)c1 |t:9,18| Show InChI InChI=1S/C24H27FN4O2/c1-3-10-29(11-4-2)24(31)18-12-16-8-9-17(13-21(16)28-22(26)14-18)23(30)27-20-7-5-6-19(25)15-20/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254753 (US9475775, 20 | US9597333, 20) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(F)c1 |t:9,18| Show InChI InChI=1S/C23H26FN5O2/c1-3-7-29(8-4-2)23(31)17-9-15-5-6-16(10-20(15)28-21(25)11-17)22(30)27-19-12-18(24)13-26-14-19/h5-6,9-10,12-14H,3-4,7-8,11H2,1-2H3,(H2,25,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254754 (US9475775, 21 | US9597333, 21) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccnc1C |t:9,18| Show InChI InChI=1S/C24H29N5O2/c1-4-11-29(12-5-2)24(31)19-13-17-8-9-18(14-21(17)27-22(25)15-19)23(30)28-20-7-6-10-26-16(20)3/h6-10,13-14H,4-5,11-12,15H2,1-3H3,(H2,25,27)(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254755 (US9475775, 22 | US9597333, 22) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(C)nc1 |t:9,18| Show InChI InChI=1S/C24H29N5O2/c1-4-10-29(11-5-2)24(31)19-12-17-7-8-18(13-21(17)28-22(25)14-19)23(30)27-20-9-6-16(3)26-15-20/h6-9,12-13,15H,4-5,10-11,14H2,1-3H3,(H2,25,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254756 (US9475775, 23 | US9597333, 23) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cc(C)cc(C)c1 |t:9,18| Show InChI InChI=1S/C26H32N4O2/c1-5-9-30(10-6-2)26(32)21-14-19-7-8-20(15-23(19)29-24(27)16-21)25(31)28-22-12-17(3)11-18(4)13-22/h7-8,11-15H,5-6,9-10,16H2,1-4H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254757 (US9475775, 24 | US9597333, 24) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(CN)cc1 |t:9,18| Show InChI InChI=1S/C25H31N5O2/c1-3-11-30(12-4-2)25(32)20-13-18-7-8-19(14-22(18)29-23(27)15-20)24(31)28-21-9-5-17(16-26)6-10-21/h5-10,13-14H,3-4,11-12,15-16,26H2,1-2H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254758 (US9475775, 25 | US9597333, 25) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(CCN)cc1 |t:9,18| Show InChI InChI=1S/C26H33N5O2/c1-3-13-31(14-4-2)26(33)21-15-19-7-8-20(16-23(19)30-24(28)17-21)25(32)29-22-9-5-18(6-10-22)11-12-27/h5-10,15-16H,3-4,11-14,17,27H2,1-2H3,(H2,28,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254759 (US9475775, 26 | US9597333, 26) Show SMILES CCCN(CCCO)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:10,19| Show InChI InChI=1S/C25H30N4O3/c1-3-10-29(11-5-12-30)25(32)20-14-18-8-9-19(15-22(18)28-23(26)16-20)24(31)27-21-7-4-6-17(2)13-21/h4,6-9,13-15,30H,3,5,10-12,16H2,1-2H3,(H2,26,28)(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254760 (US9475775, 27 | US9597333, 27) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccccc1C |t:9,18| Show InChI InChI=1S/C25H30N4O2/c1-4-12-29(13-5-2)25(31)20-14-18-10-11-19(15-22(18)27-23(26)16-20)24(30)28-21-9-7-6-8-17(21)3/h6-11,14-15H,4-5,12-13,16H2,1-3H3,(H2,26,27)(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254761 (US9475775, 28 | US9597333, 28) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(C)cc1 |t:9,18| Show InChI InChI=1S/C25H30N4O2/c1-4-12-29(13-5-2)25(31)20-14-18-8-9-19(15-22(18)28-23(26)16-20)24(30)27-21-10-6-17(3)7-11-21/h6-11,14-15H,4-5,12-13,16H2,1-3H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254762 (US9475775, 29 | US9597333, 29) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CC)c1 |t:9,18| Show InChI InChI=1S/C26H32N4O2/c1-4-12-30(13-5-2)26(32)21-15-19-10-11-20(16-23(19)29-24(27)17-21)25(31)28-22-9-7-8-18(6-3)14-22/h7-11,14-16H,4-6,12-13,17H2,1-3H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254763 (US9475775, 30 | US9597333, 30) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OC)c1 |t:9,18| Show InChI InChI=1S/C25H30N4O3/c1-4-11-29(12-5-2)25(31)19-13-17-9-10-18(14-22(17)28-23(26)15-19)24(30)27-20-7-6-8-21(16-20)32-3/h6-10,13-14,16H,4-5,11-12,15H2,1-3H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254764 (US9475775, 31 | US9597333, 31) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(c1)C(F)(F)F |t:9,18| Show InChI InChI=1S/C25H27F3N4O2/c1-3-10-32(11-4-2)24(34)18-12-16-8-9-17(13-21(16)31-22(29)14-18)23(33)30-20-7-5-6-19(15-20)25(26,27)28/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,29,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254765 (US9475775, 32 | US9597333, 32) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(Cl)c1 |t:9,18| Show InChI InChI=1S/C24H27ClN4O2/c1-3-10-29(11-4-2)24(31)18-12-16-8-9-17(13-21(16)28-22(26)14-18)23(30)27-20-7-5-6-19(25)15-20/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254766 (US9475775, 33 | US9597333, 33) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(CN)c1 |t:9,18| Show InChI InChI=1S/C24H30N6O2/c1-3-7-30(8-4-2)24(32)19-10-17-5-6-18(11-21(17)29-22(26)12-19)23(31)28-20-9-16(13-25)14-27-15-20/h5-6,9-11,14-15H,3-4,7-8,12-13,25H2,1-2H3,(H2,26,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254767 (US9475775, 34 | US9597333, 34) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccnnc1 |t:9,18| Show InChI InChI=1S/C22H26N6O2/c1-3-9-28(10-4-2)22(30)17-11-15-5-6-16(12-19(15)27-20(23)13-17)21(29)26-18-7-8-24-25-14-18/h5-8,11-12,14H,3-4,9-10,13H2,1-2H3,(H2,23,27)(H,24,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254768 (US9475775, 35 | US9597333, 35) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(OCC)nc1 |t:9,18| Show InChI InChI=1S/C25H31N5O3/c1-4-11-30(12-5-2)25(32)19-13-17-7-8-18(14-21(17)29-22(26)15-19)24(31)28-20-9-10-23(27-16-20)33-6-3/h7-10,13-14,16H,4-6,11-12,15H2,1-3H3,(H2,26,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254769 (US9475775, 36 | US9597333, 36) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CN)c1 |t:9,18| Show InChI InChI=1S/C25H31N5O2/c1-3-10-30(11-4-2)25(32)20-13-18-8-9-19(14-22(18)29-23(27)15-20)24(31)28-21-7-5-6-17(12-21)16-26/h5-9,12-14H,3-4,10-11,15-16,26H2,1-2H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254770 (US9475775, 37 | US9597333, 37) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccn(C)n1 |t:9,18| Show InChI InChI=1S/C22H28N6O2/c1-4-9-28(10-5-2)22(30)17-12-15-6-7-16(13-18(15)24-19(23)14-17)21(29)25-20-8-11-27(3)26-20/h6-8,11-13H,4-5,9-10,14H2,1-3H3,(H2,23,24)(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254771 (US9475775, 38 | US9597333, 38) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ncco1 |t:9,18| Show InChI InChI=1S/C21H25N5O3/c1-3-8-26(9-4-2)20(28)16-11-14-5-6-15(12-17(14)24-18(22)13-16)19(27)25-21-23-7-10-29-21/h5-7,10-12H,3-4,8-9,13H2,1-2H3,(H2,22,24)(H,23,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254772 (US9475775, 39 | US9597333, 39) Show SMILES CCCN(CCCO)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccnc1 |t:10,19| Show InChI InChI=1S/C23H27N5O3/c1-2-9-28(10-4-11-29)23(31)18-12-16-6-7-17(13-20(16)27-21(24)14-18)22(30)26-19-5-3-8-25-15-19/h3,5-8,12-13,15,29H,2,4,9-11,14H2,1H3,(H2,24,27)(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254773 (US9475775, 40 | US9597333, 40) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OC)c1 |t:9,18| Show InChI InChI=1S/C24H29N5O3/c1-4-8-29(9-5-2)24(31)18-10-16-6-7-17(11-21(16)28-22(25)12-18)23(30)27-19-13-20(32-3)15-26-14-19/h6-7,10-11,13-15H,4-5,8-9,12H2,1-3H3,(H2,25,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254774 (US9475775, 41 | US9597333, 41) Show SMILES CCCN(CC#C)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:9,18| Show InChI InChI=1S/C25H26N4O2/c1-4-11-29(12-5-2)25(31)20-14-18-9-10-19(15-22(18)28-23(26)16-20)24(30)27-21-8-6-7-17(3)13-21/h1,6-10,13-15H,5,11-12,16H2,2-3H3,(H2,26,28)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254775 (US9475775, 42 | US9597333, 42) Show SMILES CCCCN(CCCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:11,20| Show InChI InChI=1S/C27H34N4O2/c1-4-6-13-31(14-7-5-2)27(33)22-16-20-11-12-21(17-24(20)30-25(28)18-22)26(32)29-23-10-8-9-19(3)15-23/h8-12,15-17H,4-7,13-14,18H2,1-3H3,(H2,28,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254776 (US9475775, 43 | US9597333, 43) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cc(C)cc(CN)c1 |t:9,18| Show InChI InChI=1S/C26H33N5O2/c1-4-8-31(9-5-2)26(33)21-13-19-6-7-20(14-23(19)30-24(28)15-21)25(32)29-22-11-17(3)10-18(12-22)16-27/h6-7,10-14H,4-5,8-9,15-16,27H2,1-3H3,(H2,28,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254777 (US9475775, 44 | US9475775, 79 | US9597333, 44) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCC)c1 |t:9,18| Show InChI InChI=1S/C25H31N5O3/c1-4-9-30(10-5-2)25(32)19-11-17-7-8-18(12-22(17)29-23(26)13-19)24(31)28-20-14-21(33-6-3)16-27-15-20/h7-8,11-12,14-16H,4-6,9-10,13H2,1-3H3,(H2,26,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254778 (US9475775, 45 | US9597333, 45) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OCCOCCN)c1 |t:9,18| Show InChI InChI=1S/C28H37N5O4/c1-3-11-33(12-4-2)28(35)22-16-20-8-9-21(17-25(20)32-26(30)18-22)27(34)31-23-6-5-7-24(19-23)37-15-14-36-13-10-29/h5-9,16-17,19H,3-4,10-15,18,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254779 (US9475775, 46 | US9597333, 46) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCCCCCN)c1 |t:9,18| Show InChI InChI=1S/C28H38N6O3/c1-3-11-34(12-4-2)28(36)22-14-20-8-9-21(15-25(20)33-26(30)16-22)27(35)32-23-17-24(19-31-18-23)37-13-7-5-6-10-29/h8-9,14-15,17-19H,3-7,10-13,16,29H2,1-2H3,(H2,30,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254780 (US9475775, 47 | US9597333, 47) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(COCCOCCN)c1 |t:9,18| Show InChI InChI=1S/C29H39N5O4/c1-3-11-34(12-4-2)29(36)24-17-22-8-9-23(18-26(22)33-27(31)19-24)28(35)32-25-7-5-6-21(16-25)20-38-15-14-37-13-10-30/h5-9,16-18H,3-4,10-15,19-20,30H2,1-2H3,(H2,31,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254781 (US9475775, 48 | US9597333, 48) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(c1)C#CCN |t:9,18| Show InChI InChI=1S/C26H30N6O2/c1-3-10-32(11-4-2)26(34)21-13-19-7-8-20(14-23(19)31-24(28)15-21)25(33)30-22-12-18(6-5-9-27)16-29-17-22/h7-8,12-14,16-17H,3-4,9-11,15,27H2,1-2H3,(H2,28,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254782 (US9475775, 49 | US9597333, 49) Show SMILES CCCN(CCCOCCOCCN)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:16,25| Show InChI InChI=1S/C29H39N5O4/c1-3-11-34(12-5-13-37-15-16-38-14-10-30)29(36)24-18-22-8-9-23(19-26(22)33-27(31)20-24)28(35)32-25-7-4-6-21(2)17-25/h4,6-9,17-19H,3,5,10-16,20,30H2,1-2H3,(H2,31,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254783 (US9475775, 50 | US9597333, 50) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(CCCN)c1 |t:9,18| Show InChI InChI=1S/C26H34N6O2/c1-3-10-32(11-4-2)26(34)21-13-19-7-8-20(14-23(19)31-24(28)15-21)25(33)30-22-12-18(6-5-9-27)16-29-17-22/h7-8,12-14,16-17H,3-6,9-11,15,27H2,1-2H3,(H2,28,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254784 (US9475775, 51 | US9597333, 51) Show SMILES CCCN(CCC(F)(F)F)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:12,21| Show InChI InChI=1S/C25H27F3N4O2/c1-3-10-32(11-9-25(26,27)28)24(34)19-13-17-7-8-18(14-21(17)31-22(29)15-19)23(33)30-20-6-4-5-16(2)12-20/h4-8,12-14H,3,9-11,15H2,1-2H3,(H2,29,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254785 (US9475775, 52 | US9597333, 52) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(\C=C/CN)c1 |t:9,18| Show InChI InChI=1S/C26H32N6O2/c1-3-10-32(11-4-2)26(34)21-13-19-7-8-20(14-23(19)31-24(28)15-21)25(33)30-22-12-18(6-5-9-27)16-29-17-22/h5-8,12-14,16-17H,3-4,9-11,15,27H2,1-2H3,(H2,28,31)(H,30,33)/b6-5-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254786 (US9475775, 53 | US9597333, 53) Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:11,20| Show InChI InChI=1S/C26H30N4O2/c1-3-11-30(16-18-7-8-18)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-6-4-5-17(2)12-22/h4-6,9-10,12-14,18H,3,7-8,11,15-16H2,1-2H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254750 (US9475775, 17 | US9475775, 54 | US9597333, 54) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCN)c1 |t:9,18| Show InChI InChI=1S/C26H33N5O2/c1-3-12-31(13-4-2)26(33)21-15-19-8-9-20(16-23(19)30-24(28)17-21)25(32)29-22-7-5-6-18(14-22)10-11-27/h5-9,14-16H,3-4,10-13,17,27H2,1-2H3,(H2,28,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254788 (US9475775, 55 | US9597333, 55) Show SMILES CCCN(CC(C)C)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:10,19| Show InChI InChI=1S/C26H32N4O2/c1-5-11-30(16-17(2)3)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-8-6-7-18(4)12-22/h6-10,12-14,17H,5,11,15-16H2,1-4H3,(H2,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254789 (US9475775, 56 | US9597333, 56) Show SMILES CCCN(CCCOCCCN)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:14,23| Show InChI InChI=1S/C28H37N5O3/c1-3-12-33(13-6-15-36-14-5-11-29)28(35)23-17-21-9-10-22(18-25(21)32-26(30)19-23)27(34)31-24-8-4-7-20(2)16-24/h4,7-10,16-18H,3,5-6,11-15,19,29H2,1-2H3,(H2,30,32)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254790 (US9475775, 57 | US9597333, 57) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCCCCN)c1 |t:9,18| Show InChI InChI=1S/C29H39N5O2/c1-3-15-34(16-4-2)29(36)24-18-22-12-13-23(19-26(22)33-27(31)20-24)28(35)32-25-11-8-10-21(17-25)9-6-5-7-14-30/h8,10-13,17-19H,3-7,9,14-16,20,30H2,1-2H3,(H2,31,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254791 (US9475775, 58 | US9597333, 58) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(CCCCCN)cc1 |t:9,18| Show InChI InChI=1S/C29H39N5O2/c1-3-16-34(17-4-2)29(36)24-18-22-11-12-23(19-26(22)33-27(31)20-24)28(35)32-25-13-9-21(10-14-25)8-6-5-7-15-30/h9-14,18-19H,3-8,15-17,20,30H2,1-2H3,(H2,31,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254792 (US9475775, 59 | US9597333, 59) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCCN)c1 |t:9,18| Show InChI InChI=1S/C27H35N5O2/c1-3-13-32(14-4-2)27(34)22-16-20-10-11-21(17-24(20)31-25(29)18-22)26(33)30-23-9-5-7-19(15-23)8-6-12-28/h5,7,9-11,15-17H,3-4,6,8,12-14,18,28H2,1-2H3,(H2,29,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254793 (US9475775, 60 | US9597333, 60) Show SMILES CCCN(Cc1ccc(CN)cc1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1 |t:16,25| Show InChI InChI=1S/C30H33N5O2/c1-3-13-35(19-22-9-7-21(18-31)8-10-22)30(37)25-15-23-11-12-24(16-27(23)34-28(32)17-25)29(36)33-26-6-4-5-20(2)14-26/h4-12,14-16H,3,13,17-19,31H2,1-2H3,(H2,32,34)(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM254794 (US9475775, 61 | US9597333, 61) Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(CCCN)cc1 |t:9,18| Show InChI InChI=1S/C27H35N5O2/c1-3-14-32(15-4-2)27(34)22-16-20-9-10-21(17-24(20)31-25(29)18-22)26(33)30-23-11-7-19(8-12-23)6-5-13-28/h7-12,16-17H,3-6,13-15,18,28H2,1-2H3,(H2,29,31)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...				US Patent US9475775 (2016) BindingDB Entry DOI: 10.7270/Q2QC02D4
					More data for this Ligand-Target Pair

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