Compile Data Set for Download or QSAR

Found 34 hits Enz. Inhib. hit(s) with all data for entry = 50035782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50251742 ((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...) Show SMILES CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18-,19+,20+,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neprilysin (Rattus norvegicus (Rat))	BDBM50251742 ((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...) Show SMILES CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18-,19+,20+,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017742 (CHEMBL316180 | disodium 2-benzyl-4-(3-carboxylatop...) Show SMILES [O-]C(=O)CCCNC(=O)[C@@H](C[C@@H](Cc1ccccc1)C([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C23H27NO5/c25-21(26)12-7-13-24-22(27)19(14-17-8-3-1-4-9-17)16-20(23(28)29)15-18-10-5-2-6-11-18/h1-6,8-11,19-20H,7,12-16H2,(H,24,27)(H,25,26)(H,28,29)/p-2/t19-,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017736 (2-Benzyl-4-(3-carboxy-propionylamino)-5-phenyl-pen...) Show SMILES OC(=O)CCC(=O)NC(C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(11-12-21(25)26)23-19(14-17-9-5-2-6-10-17)15-18(22(27)28)13-16-7-3-1-4-8-16/h1-10,18-19H,11-15H2,(H,23,24)(H,25,26)(H,27,28)/t18-,19?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM21641 (2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...) Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neprilysin (Rattus norvegicus (Rat))	BDBM50017755 (2-Benzyl-4-(carboxymethyl-carbamoyl)-5-phenyl-pent...) Show SMILES OC(=O)CNC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C21H23NO5/c23-19(24)14-22-20(25)17(11-15-7-3-1-4-8-15)13-18(21(26)27)12-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2,(H,22,25)(H,23,24)(H,26,27)/t17-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017734 (2-Benzyl-4-(2-benzylsulfanyl-1-carboxy-ethylcarbam...) Show SMILES OC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(=O)NC(CSCc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C29H31NO5S/c31-27(30-26(29(34)35)20-36-19-23-14-8-3-9-15-23)24(16-21-10-4-1-5-11-21)18-25(28(32)33)17-22-12-6-2-7-13-22/h1-15,24-26H,16-20H2,(H,30,31)(H,32,33)(H,34,35)/t24-,25-,26?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM21641 (2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...) Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neprilysin (Rattus norvegicus (Rat))	BDBM50017741 (2-Benzyl-4-(1-carboxy-3-phenyl-propylcarbamoyl)-5-...) Show SMILES OC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(=O)NC(CCc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C29H31NO5/c31-27(30-26(29(34)35)17-16-21-10-4-1-5-11-21)24(18-22-12-6-2-7-13-22)20-25(28(32)33)19-23-14-8-3-9-15-23/h1-15,24-26H,16-20H2,(H,30,31)(H,32,33)(H,34,35)/t24-,25-,26?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017733 ((2S,4S)-2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-ph...) Show SMILES OC(=O)CCNC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(25)11-12-23-21(26)18(13-16-7-3-1-4-8-16)15-19(22(27)28)14-17-9-5-2-6-10-17/h1-10,18-19H,11-15H2,(H,23,26)(H,24,25)(H,27,28)/t18-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibitory activity against Enkephalinase from rabbit using method 2 is determined.				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017752 (2-Benzyl-4-(2-benzyloxy-1-carboxy-ethylcarbamoyl)-...) Show SMILES OC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(=O)NC(COCc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C29H31NO6/c31-27(30-26(29(34)35)20-36-19-23-14-8-3-9-15-23)24(16-21-10-4-1-5-11-21)18-25(28(32)33)17-22-12-6-2-7-13-22/h1-15,24-26H,16-20H2,(H,30,31)(H,32,33)(H,34,35)/t24-,25-,26?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017733 ((2S,4S)-2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-ph...) Show SMILES OC(=O)CCNC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(25)11-12-23-21(26)18(13-16-7-3-1-4-8-16)15-19(22(27)28)14-17-9-5-2-6-10-17/h1-10,18-19H,11-15H2,(H,23,26)(H,24,25)(H,27,28)/t18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017738 (CHEMBL316172 | N-(4-Hydroxy-3-methoxy-benzyl)-2-me...) Show SMILES COc1cc(CNC(=O)C(CS)Cc2ccccc2)ccc1O Show InChI InChI=1S/C18H21NO3S/c1-22-17-10-14(7-8-16(17)20)11-19-18(21)15(12-23)9-13-5-3-2-4-6-13/h2-8,10,15,20,23H,9,11-12H2,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017743 (2-Benzyl-4-(3-carboxy-propionylamino)-5-phenyl-pen...) Show SMILES OC(=O)CCC(=O)NC(CC(Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(11-12-21(25)26)23-19(14-17-9-5-2-6-10-17)15-18(22(27)28)13-16-7-3-1-4-8-16/h1-10,18-19H,11-15H2,(H,23,24)(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017756 (CHEMBL83326 | N-(3,4-Dihydroxy-benzyl)-2-mercaptom...) Show SMILES Oc1ccc(CNC(=O)C(CS)Cc2ccccc2)cc1O Show InChI InChI=1S/C17H19NO3S/c19-15-7-6-13(9-16(15)20)10-18-17(21)14(11-22)8-12-4-2-1-3-5-12/h1-7,9,14,19-20,22H,8,10-11H2,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017750 (2-Benzyl-4-(4-carboxy-butyrylamino)-5-phenyl-penta...) Show SMILES OC(=O)CCCC(=O)NC(CC(Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C23H27NO5/c25-21(12-7-13-22(26)27)24-20(15-18-10-5-2-6-11-18)16-19(23(28)29)14-17-8-3-1-4-9-17/h1-6,8-11,19-20H,7,12-16H2,(H,24,25)(H,26,27)(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50034866 (2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pen...) Show SMILES OC(=O)CCNC(=O)C(CC(Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(25)11-12-23-21(26)18(13-16-7-3-1-4-8-16)15-19(22(27)28)14-17-9-5-2-6-10-17/h1-10,18-19H,11-15H2,(H,23,26)(H,24,25)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description 50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation for 4 min at 37 degree C				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017751 (CHEMBL430436 | Sodium; 2-benzyl-4-(3,4-dihydroxy-b...) Show SMILES Oc1ccc(CNC(=O)[C@@H](C[C@@H](Cc2ccccc2)C([O-])=O)Cc2ccccc2)cc1O Show InChI InChI=1S/C26H27NO5/c28-23-12-11-20(15-24(23)29)17-27-25(30)21(13-18-7-3-1-4-8-18)16-22(26(31)32)14-19-9-5-2-6-10-19/h1-12,15,21-22,28-29H,13-14,16-17H2,(H,27,30)(H,31,32)/p-1/t21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017758 (2-Benzyl-4-(2-carboxymethyl-phenylcarbamoyl)-5-phe...) Show SMILES OC(=O)Cc1ccccc1NC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C27H27NO5/c29-25(30)18-21-13-7-8-14-24(21)28-26(31)22(15-19-9-3-1-4-10-19)17-23(27(32)33)16-20-11-5-2-6-12-20/h1-14,22-23H,15-18H2,(H,28,31)(H,29,30)(H,32,33)/t22-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017747 (CHEMBL311093 | disodium 2-benzyl-4-(1-carboxylato-...) Show SMILES [O-]C(=O)[C@@H](C[C@@H](Cc1ccccc1)C(=O)NC(Cc1ccccc1)C([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C28H29NO5/c30-26(29-25(28(33)34)18-22-14-8-3-9-15-22)23(16-20-10-4-1-5-11-20)19-24(27(31)32)17-21-12-6-2-7-13-21/h1-15,23-25H,16-19H2,(H,29,30)(H,31,32)(H,33,34)/p-2/t23-,24-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017759 (5-(2-Benzyl-4-carboxy-5-phenyl-pentanoylamino)-2-h...) Show SMILES OC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(=O)Nc1ccc(O)c(c1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C26H25NO6/c28-23-12-11-21(16-22(23)26(32)33)27-24(29)19(13-17-7-3-1-4-8-17)15-20(25(30)31)14-18-9-5-2-6-10-18/h1-12,16,19-20,28H,13-15H2,(H,27,29)(H,30,31)(H,32,33)/t19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017735 (2-Benzyl-4-(1-carboxy-3-methyl-butylcarbamoyl)-5-p...) Show SMILES CC(C)CC(NC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C25H31NO5/c1-17(2)13-22(25(30)31)26-23(27)20(14-18-9-5-3-6-10-18)16-21(24(28)29)15-19-11-7-4-8-12-19/h3-12,17,20-22H,13-16H2,1-2H3,(H,26,27)(H,28,29)(H,30,31)/t20-,21-,22?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017754 (2-Benzyl-4-(3-carboxy-propylcarbamoyl)-5-phenyl-pe...) Show SMILES OC(=O)CCCNC(=O)C(CC(Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C23H27NO5/c25-21(26)12-7-13-24-22(27)19(14-17-8-3-1-4-9-17)16-20(23(28)29)15-18-10-5-2-6-11-18/h1-6,8-11,19-20H,7,12-16H2,(H,24,27)(H,25,26)(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50017757 (2-Benzyl-4-(2-carboxy-acetylamino)-5-phenyl-pentan...) Show SMILES OC(=O)CC(=O)NC(CC(Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C21H23NO5/c23-19(14-20(24)25)22-18(12-16-9-5-2-6-10-16)13-17(21(26)27)11-15-7-3-1-4-8-15/h1-10,17-18H,11-14H2,(H,22,23)(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in membranes prepared from rabbit				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017745 (CHEMBL421724 | disodium 2-benzyl-4-[1-carboxylato-...) Show SMILES [O-]C(=O)[C@@H](C[C@@H](Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C30H30N2O5/c33-28(32-27(30(36)37)18-24-19-31-26-14-8-7-13-25(24)26)22(15-20-9-3-1-4-10-20)17-23(29(34)35)16-21-11-5-2-6-12-21/h1-14,19,22-23,27,31H,15-18H2,(H,32,33)(H,34,35)(H,36,37)/p-2/t22-,23-,27?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017746 (CHEMBL85324 | disodium 2-benzyl-4-(3-carboxylatoph...) Show SMILES [O-]C(=O)[C@H](C[C@H](Cc1ccccc1)C(=O)Nc1cccc(c1)C([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C26H25NO5/c28-24(27-23-13-7-12-20(17-23)25(29)30)21(14-18-8-3-1-4-9-18)16-22(26(31)32)15-19-10-5-2-6-11-19/h1-13,17,21-22H,14-16H2,(H,27,28)(H,29,30)(H,31,32)/p-2/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017760 (4-(2-Benzyl-4-carboxy-5-phenyl-pentanoylamino)-ben...) Show SMILES OC(=O)[C@H](C[C@H](Cc1ccccc1)C(=O)Nc1ccc(cc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C26H25NO5/c28-24(27-23-13-11-20(12-14-23)25(29)30)21(15-18-7-3-1-4-8-18)17-22(26(31)32)16-19-9-5-2-6-10-19/h1-14,21-22H,15-17H2,(H,27,28)(H,29,30)(H,31,32)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017753 (2-(2-Benzyl-4-carboxy-5-phenyl-pentanoylamino)-ben...) Show SMILES OC(=O)C(CC(Cc1ccccc1)C(=O)Nc1ccccc1C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C26H25NO5/c28-24(27-23-14-8-7-13-22(23)26(31)32)20(15-18-9-3-1-4-10-18)17-21(25(29)30)16-19-11-5-2-6-12-19/h1-14,20-21H,15-17H2,(H,27,28)(H,29,30)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50405873 (CHEMBL2114199) Show SMILES OC(=O)CCNC(=O)[C@H](C[C@H](Cc1ccccc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H25NO5/c24-20(25)11-12-23-21(26)18(13-16-7-3-1-4-8-16)15-19(22(27)28)14-17-9-5-2-6-10-17/h1-10,18-19H,11-15H2,(H,23,26)(H,24,25)(H,27,28)/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017749 (CHEMBL84865 | disodium 4-(2-carboxylatoethylcarbam...) Show SMILES [O-]C(=O)CCNC(=O)C(CC(CC1CCCCC1)C([O-])=O)CC1CCCCC1 Show InChI InChI=1S/C22H37NO5/c24-20(25)11-12-23-21(26)18(13-16-7-3-1-4-8-16)15-19(22(27)28)14-17-9-5-2-6-10-17/h16-19H,1-15H2,(H,23,26)(H,24,25)(H,27,28)/p-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017748 (CHEMBL84258 | Sodium; 2-benzyl-4-(3-hydroxy-propyl...) Show SMILES OCCCNC(=O)C(CC(Cc1ccccc1)C([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C22H27NO4/c24-13-7-12-23-21(25)19(14-17-8-3-1-4-9-17)16-20(22(26)27)15-18-10-5-2-6-11-18/h1-6,8-11,19-20,24H,7,12-16H2,(H,23,25)(H,26,27)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017740 (4-(2-Carboxy-ethylcarbamoyl)-2-phenethyl-6-phenyl-...) Show SMILES OC(=O)CCNC(=O)C(CCc1ccccc1)CC(CCc1ccccc1)C(O)=O Show InChI InChI=1S/C24H29NO5/c26-22(27)15-16-25-23(28)20(13-11-18-7-3-1-4-8-18)17-21(24(29)30)14-12-19-9-5-2-6-10-19/h1-10,20-21H,11-17H2,(H,25,28)(H,26,27)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017739 (2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pen...) Show SMILES CCOC(=O)C(CC(Cc1ccccc1)C(=O)NCCC(O)=O)Cc1ccccc1 Show InChI InChI=1S/C24H29NO5/c1-2-30-24(29)21(16-19-11-7-4-8-12-19)17-20(15-18-9-5-3-6-10-18)23(28)25-14-13-22(26)27/h3-12,20-21H,2,13-17H2,1H3,(H,25,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50017737 (2-Benzyl-4-(2-cyano-ethylcarbamoyl)-5-phenyl-penta...) Show SMILES OC(=O)C(CC(Cc1ccccc1)C(=O)NCCC#N)Cc1ccccc1 Show InChI InChI=1S/C22H24N2O3/c23-12-7-13-24-21(25)19(14-17-8-3-1-4-9-17)16-20(22(26)27)15-18-10-5-2-6-11-18/h1-6,8-11,19-20H,7,13-16H2,(H,24,25)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by ChEMBL					Assay Description Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatum				J Med Chem 32: 2519-26 (1989) BindingDB Entry DOI: 10.7270/Q2668DSV
					More data for this Ligand-Target Pair