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Compile Data Set for Download or QSAR

Found 121 hits Enz. Inhib. hit(s) with all data for entry = 50006566   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407819
PNG
(CHEMBL2115152)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1
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PubMed
4.40E+4n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50030627
PNG
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)
Show SMILES CC(N)(C(O)=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)
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PubMed
5.00E+4n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards mGluR1a was determined


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50076393
PNG
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1
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5.00E+4n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407823
PNG
(CHEMBL2114116)
Show SMILES N[C@@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m0/s1
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6.00E+4n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407827
PNG
(CHEMBL2115160)
Show SMILES N[C@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m0/s1
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1.35E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407824
PNG
(CHEMBL2114115)
Show SMILES N[C@@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m1/s1
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2.05E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407822
PNG
(CHEMBL2114112)
Show SMILES N[C@@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m0/s1
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2.60E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50076393
PNG
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407831
PNG
(CHEMBL2115156)
Show SMILES N[C@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10-/m1/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407830
PNG
(CHEMBL2115157)
Show SMILES N[C@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m0/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407829
PNG
(CHEMBL2115153)
Show SMILES N[C@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m0/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407825
PNG
(CHEMBL2114110)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407821
PNG
(CHEMBL2115151)
Show SMILES N[C@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m1/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407818
PNG
(CHEMBL2114109)
Show SMILES N[C@@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m1/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407820
PNG
(CHEMBL2115159)
Show SMILES N[C@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m1/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407828
PNG
(CHEMBL2114106)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407826
PNG
(CHEMBL2114105)
Show SMILES N[C@@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m1/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407825
PNG
(CHEMBL2114110)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1
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>2.70E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor mGluR1


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407823
PNG
(CHEMBL2114116)
Show SMILES N[C@@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407828
PNG
(CHEMBL2114106)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407824
PNG
(CHEMBL2114115)
Show SMILES N[C@@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407822
PNG
(CHEMBL2114112)
Show SMILES N[C@@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407821
PNG
(CHEMBL2115151)
Show SMILES N[C@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407831
PNG
(CHEMBL2115156)
Show SMILES N[C@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10-/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407827
PNG
(CHEMBL2115160)
Show SMILES N[C@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407829
PNG
(CHEMBL2115153)
Show SMILES N[C@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407826
PNG
(CHEMBL2114105)
Show SMILES N[C@@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407818
PNG
(CHEMBL2114109)
Show SMILES N[C@@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407825
PNG
(CHEMBL2114110)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407819
PNG
(CHEMBL2115152)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407820
PNG
(CHEMBL2115159)
Show SMILES N[C@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m1/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407830
PNG
(CHEMBL2115157)
Show SMILES N[C@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m0/s1
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>2.80E+5n/an/an/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards metabotropic glutamate receptor mGluR4a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50076393
PNG
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1
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n/an/a 8.00E+3n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50030627
PNG
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)
Show SMILES CC(N)(C(O)=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Antagonistic activity against mGluR2 was determined


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407819
PNG
(CHEMBL2115152)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1
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n/an/a 1.40E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50407823
PNG
(CHEMBL2114116)
Show SMILES N[C@@H]([C@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP formation in BHK cells expressing mGluR2


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407821
PNG
(CHEMBL2115151)
Show SMILES N[C@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP formation in BHK cells expressing mGluR4


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50407831
PNG
(CHEMBL2115156)
Show SMILES N[C@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50407830
PNG
(CHEMBL2115157)
Show SMILES N[C@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50407819
PNG
(CHEMBL2115152)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50407829
PNG
(CHEMBL2115153)
Show SMILES N[C@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407826
PNG
(CHEMBL2114105)
Show SMILES N[C@@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407828
PNG
(CHEMBL2114106)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50407824
PNG
(CHEMBL2114115)
Show SMILES N[C@@H]([C@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10+/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50076393
PNG
((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9+,10+/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407828
PNG
(CHEMBL2114106)
Show SMILES N[C@@H]([C@@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407826
PNG
(CHEMBL2114105)
Show SMILES N[C@@H]([C@@H]1[C@@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10+/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407818
PNG
(CHEMBL2114109)
Show SMILES N[C@@H]([C@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407825
PNG
(CHEMBL2114110)
Show SMILES N[C@H]([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50407822
PNG
(CHEMBL2114112)
Show SMILES N[C@@H]([C@H]1[C@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8+,9-,10-/m0/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1a


J Med Chem 39: 2259-69 (1996)


Article DOI: 10.1021/jm960059+
BindingDB Entry DOI: 10.7270/Q2Z60N5G
More data for this
Ligand-Target Pair
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