Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with all data for entry = 50011675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109222 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-isobutoxy-phenyl)...) Show SMILES CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C40H44FN5O4/c1-6-31(7-2)50-40(48)34-24-45(23-29-12-8-9-14-35(29)41)38-33(22-42)37(28-15-17-32(18-16-28)49-26-27(3)4)36(46(38)39(34)47)25-44(5)21-19-30-13-10-11-20-43-30/h8-18,20,24,27,31H,6-7,19,21,23,25-26H2,1-5H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109203 (8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...) Show SMILES CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC2CCCC2)cc1 Show InChI InChI=1S/C41H44FN5O4/c1-4-31(5-2)51-41(49)35-26-46(25-29-12-6-9-16-36(29)42)39-34(24-43)38(28-17-19-33(20-18-28)50-32-14-7-8-15-32)37(47(39)40(35)48)27-45(3)23-21-30-13-10-11-22-44-30/h6,9-13,16-20,22,26,31-32H,4-5,7-8,14-15,21,23,25,27H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109207 (8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...) Show SMILES CN(CCc1ccccn1)Cc1c(c(C#N)c2n(Cc3ccccc3F)cc(C(=O)OC3CCCC3)c(=O)n12)-c1ccc(OC2CCCC2)cc1 Show InChI InChI=1S/C41H42FN5O4/c1-45(23-21-30-11-8-9-22-44-30)27-37-38(28-17-19-33(20-18-28)50-31-12-3-4-13-31)34(24-43)39-46(25-29-10-2-7-16-36(29)42)26-35(40(48)47(37)39)41(49)51-32-14-5-6-15-32/h2,7-11,16-20,22,26,31-32H,3-6,12-15,21,23,25,27H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109211 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-isobutoxy-phenyl)...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C37H38FN5O4/c1-5-46-37(45)31-22-42(21-27-10-6-7-12-32(27)38)35-30(20-39)34(26-13-15-29(16-14-26)47-24-25(2)3)33(43(35)36(31)44)23-41(4)19-17-28-11-8-9-18-40-28/h6-16,18,22,25H,5,17,19,21,23-24H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109205 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C37H38FN5O4/c1-5-28(6-2)47-37(45)31-23-42(22-26-11-7-8-13-32(26)38)35-30(21-39)34(25-14-16-29(46-4)17-15-25)33(43(35)36(31)44)24-41(3)20-18-27-12-9-10-19-40-27/h7-17,19,23,28H,5-6,18,20,22,24H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109212 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES COc1ccc(cc1)-c1c(CN(C)CCc2ccccn2)n2c(c1C#N)n(Cc1ccccc1F)cc(C(=O)OC1CCCC1)c2=O Show InChI InChI=1S/C37H36FN5O4/c1-41(20-18-27-10-7-8-19-40-27)24-33-34(25-14-16-28(46-2)17-15-25)30(21-39)35-42(22-26-9-3-6-13-32(26)38)23-31(36(44)43(33)35)37(45)47-29-11-4-5-12-29/h3,6-10,13-17,19,23,29H,4-5,11-12,18,20,22,24H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109231 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES COc1ccc(cc1)-c1c(CN(C)CCc2ccccn2)n2c(c1C#N)n(Cc1ccccc1F)cc(C(=O)OC(C)C)c2=O Show InChI InChI=1S/C35H34FN5O4/c1-23(2)45-35(43)29-21-40(20-25-9-5-6-11-30(25)36)33-28(19-37)32(24-12-14-27(44-4)15-13-24)31(41(33)34(29)42)22-39(3)18-16-26-10-7-8-17-38-26/h5-15,17,21,23H,16,18,20,22H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109209 (8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C37H37F2N5O4/c1-5-47-37(46)31-21-43(20-26-9-12-27(38)18-32(26)39)35-30(19-40)34(25-10-13-29(14-11-25)48-23-24(2)3)33(44(35)36(31)45)22-42(4)17-15-28-8-6-7-16-41-28/h6-14,16,18,21,24H,5,15,17,20,22-23H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109227 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H32FN5O4/c1-4-44-34(42)28-21-39(20-24-9-5-6-11-29(24)35)32-27(19-36)31(23-12-14-26(43-3)15-13-23)30(40(32)33(28)41)22-38(2)18-16-25-10-7-8-17-37-25/h5-15,17,21H,4,16,18,20,22H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109201 (8-Cyano-1-(2,6-difluoro-benzyl)-7-(4-isobutoxy-phe...) Show SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C37H37F2N5O4/c1-5-47-37(46)30-21-43(20-29-31(38)10-8-11-32(29)39)35-28(19-40)34(25-12-14-27(15-13-25)48-23-24(2)3)33(44(35)36(30)45)22-42(4)18-16-26-9-6-7-17-41-26/h6-15,17,21,24H,5,16,18,20,22-23H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109226 (8-Cyano-1-(2,5-difluoro-benzyl)-7-(4-isobutoxy-phe...) Show SMILES CCOC(=O)c1cn(Cc2cc(F)ccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C37H37F2N5O4/c1-5-47-37(46)31-21-43(20-26-18-27(38)11-14-32(26)39)35-30(19-40)34(25-9-12-29(13-10-25)48-23-24(2)3)33(44(35)36(31)45)22-42(4)17-15-28-8-6-7-16-41-28/h6-14,16,18,21,24H,5,15,17,20,22-23H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109217 (6-[(Benzyl-methyl-amino)-methyl]-8-cyano-1-(2-fluo...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)Cc3ccccc3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H31FN4O4/c1-4-43-34(41)28-21-38(20-25-12-8-9-13-29(25)35)32-27(18-36)31(24-14-16-26(42-3)17-15-24)30(39(32)33(28)40)22-37(2)19-23-10-6-5-7-11-23/h5-17,21H,4,19-20,22H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109214 (8-Cyano-1-(2,6-difluoro-benzyl)-7-(4-methoxy-pheny...) Show SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H31F2N5O4/c1-4-45-34(43)27-20-40(19-26-28(35)9-7-10-29(26)36)32-25(18-37)31(22-11-13-24(44-3)14-12-22)30(41(32)33(27)42)21-39(2)17-15-23-8-5-6-16-38-23/h5-14,16,20H,4,15,17,19,21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109230 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES COc1ccc(cc1)-c1c(CN(C)CCc2ccccn2)n2c(c1C#N)n(Cc1ccccc1F)cc(C(=O)OC1CCOC1)c2=O Show InChI InChI=1S/C36H34FN5O5/c1-40(17-14-26-8-5-6-16-39-26)22-32-33(24-10-12-27(45-2)13-11-24)29(19-38)34-41(20-25-7-3-4-9-31(25)37)21-30(35(43)42(32)34)36(44)47-28-15-18-46-23-28/h3-13,16,21,28H,14-15,17-18,20,22-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109216 (8-Cyano-7-(4-isobutoxy-phenyl)-1-(2-methoxy-benzyl...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2OC)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C38H41N5O5/c1-6-47-38(45)32-23-42(22-28-11-7-8-13-34(28)46-5)36-31(21-39)35(27-14-16-30(17-15-27)48-25-26(2)3)33(43(36)37(32)44)24-41(4)20-18-29-12-9-10-19-40-29/h7-17,19,23,26H,6,18,20,22,24-25H2,1-5H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109224 (8-Cyano-1-(2,3-difluoro-benzyl)-7-(4-methoxy-pheny...) Show SMILES CCOC(=O)c1cn(Cc2cccc(F)c2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H31F2N5O4/c1-4-45-34(43)27-20-40(19-23-8-7-10-28(35)31(23)36)32-26(18-37)30(22-11-13-25(44-3)14-12-22)29(41(32)33(27)42)21-39(2)17-15-24-9-5-6-16-38-24/h5-14,16,20H,4,15,17,19,21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109213 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES COc1ccc(cc1)-c1c(CN(C)CCc2ccccn2)n2c(c1C#N)n(Cc1ccccc1F)cc(C(=O)OC(C1CC1)C1CC1)c2=O Show InChI InChI=1S/C39H38FN5O4/c1-43(20-18-29-8-5-6-19-42-29)24-34-35(25-14-16-30(48-2)17-15-25)31(21-41)37-44(22-28-7-3-4-9-33(28)40)23-32(38(46)45(34)37)39(47)49-36(26-10-11-26)27-12-13-27/h3-9,14-17,19,23,26-27,36H,10-13,18,20,22,24H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109210 (1-Benzyl-8-cyano-7-(4-methoxy-phenyl)-6-{[methyl-(...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H33N5O4/c1-4-43-34(41)29-22-38(21-24-10-6-5-7-11-24)32-28(20-35)31(25-13-15-27(42-3)16-14-25)30(39(32)33(29)40)23-37(2)19-17-26-12-8-9-18-36-26/h5-16,18,22H,4,17,19,21,23H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109228 (8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-methoxy-pheny...) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H31F2N5O4/c1-4-45-34(43)28-20-40(19-23-8-11-24(35)17-29(23)36)32-27(18-37)31(22-9-12-26(44-3)13-10-22)30(41(32)33(28)42)21-39(2)16-14-25-7-5-6-15-38-25/h5-13,15,17,20H,4,14,16,19,21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109218 (8-Cyano-1-(2-cyano-benzyl)-7-(4-methoxy-phenyl)-6-...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2C#N)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C35H32N6O4/c1-4-45-35(43)30-22-40(21-26-10-6-5-9-25(26)19-36)33-29(20-37)32(24-12-14-28(44-3)15-13-24)31(41(33)34(30)42)23-39(2)18-16-27-11-7-8-17-38-27/h5-15,17,22H,4,16,18,21,23H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109221 (8-Cyano-1-(2,5-difluoro-benzyl)-7-(4-methoxy-pheny...) Show SMILES CCOC(=O)c1cn(Cc2cc(F)ccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H31F2N5O4/c1-4-45-34(43)28-20-40(19-23-17-24(35)10-13-29(23)36)32-27(18-37)31(22-8-11-26(44-3)12-9-22)30(41(32)33(28)42)21-39(2)16-14-25-7-5-6-15-38-25/h5-13,15,17,20H,4,14,16,19,21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109220 (8-Cyano-1-(2-methoxy-benzyl)-7-(4-methoxy-phenyl)-...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2OC)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C35H35N5O5/c1-5-45-35(42)29-22-39(21-25-10-6-7-12-31(25)44-4)33-28(20-36)32(24-13-15-27(43-3)16-14-24)30(40(33)34(29)41)23-38(2)19-17-26-11-8-9-18-37-26/h6-16,18,22H,5,17,19,21,23H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50109222 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-isobutoxy-phenyl)...) Show SMILES CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C40H44FN5O4/c1-6-31(7-2)50-40(48)34-24-45(23-29-12-8-9-14-35(29)41)38-33(22-42)37(28-15-17-32(18-16-28)49-26-27(3)4)36(46(38)39(34)47)25-44(5)21-19-30-13-10-11-20-43-30/h8-18,20,24,27,31H,6-7,19,21,23,25-26H2,1-5H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50109203 (8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...) Show SMILES CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC2CCCC2)cc1 Show InChI InChI=1S/C41H44FN5O4/c1-4-31(5-2)51-41(49)35-26-46(25-29-12-6-9-16-36(29)42)39-34(24-43)38(28-17-19-33(20-18-28)50-32-14-7-8-15-32)37(47(39)40(35)48)27-45(3)23-21-30-13-10-11-22-44-30/h6,9-13,16-20,22,26,31-32H,4-5,7-8,14-15,21,23,25,27H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50109205 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C37H38FN5O4/c1-5-28(6-2)47-37(45)31-23-42(22-26-11-7-8-13-32(26)38)35-30(21-39)34(25-14-16-29(46-4)17-15-25)33(43(35)36(31)44)24-41(3)20-18-27-12-9-10-19-40-27/h7-17,19,23,28H,5-6,18,20,22,24H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109229 (1-(2-Chloro-benzyl)-8-cyano-7-(4-methoxy-phenyl)-6...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2Cl)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H32ClN5O4/c1-4-44-34(42)28-21-39(20-24-9-5-6-11-29(24)35)32-27(19-36)31(23-12-14-26(43-3)15-13-23)30(40(32)33(28)41)22-38(2)18-16-25-10-7-8-17-37-25/h5-15,17,21H,4,16,18,20,22H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50109207 (8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...) Show SMILES CN(CCc1ccccn1)Cc1c(c(C#N)c2n(Cc3ccccc3F)cc(C(=O)OC3CCCC3)c(=O)n12)-c1ccc(OC2CCCC2)cc1 Show InChI InChI=1S/C41H42FN5O4/c1-45(23-21-30-11-8-9-22-44-30)27-37-38(28-17-19-33(20-18-28)50-31-12-3-4-13-31)34(24-43)39-46(25-29-10-2-7-16-36(29)42)26-35(40(48)47(37)39)41(49)51-32-14-5-6-15-32/h2,7-11,16-20,22,26,31-32H,3-6,12-15,21,23,25,27H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109204 (8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2F)c2c(C#N)c(c(CN(C)CCc3cccnc3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C37H37F2N5O4/c1-5-47-37(46)31-21-43(20-27-8-11-28(38)17-32(27)39)35-30(18-40)34(26-9-12-29(13-10-26)48-23-24(2)3)33(44(35)36(31)45)22-42(4)16-14-25-7-6-15-41-19-25/h6-13,15,17,19,21,24H,5,14,16,20,22-23H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109223 (1-Benzyl-6-[(benzyl-methyl-amino)-methyl]-8-cyano-...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2c(C#N)c(c(CN(C)Cc3ccccc3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H32N4O4/c1-4-42-34(40)29-22-37(21-25-13-9-6-10-14-25)32-28(19-35)31(26-15-17-27(41-3)18-16-26)30(38(32)33(29)39)23-36(2)20-24-11-7-5-8-12-24/h5-18,22H,4,20-21,23H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109225 (8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2F)c2c(C#N)c(c(CN(C)CCc3ccccc3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C38H38F2N4O4/c1-5-47-38(46)32-22-43(21-28-11-14-29(39)19-33(28)40)36-31(20-41)35(27-12-15-30(16-13-27)48-24-25(2)3)34(44(36)37(32)45)23-42(4)18-17-26-9-7-6-8-10-26/h6-16,19,22,25H,5,17-18,21,23-24H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109215 (1-Benzyl-8-cyano-6-dimethylaminomethyl-7-(4-methox...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2c(C#N)c(c(CN(C)C)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C28H28N4O4/c1-5-36-28(34)23-17-31(16-19-9-7-6-8-10-19)26-22(15-29)25(20-11-13-21(35-4)14-12-20)24(18-30(2)3)32(26)27(23)33/h6-14,17H,5,16,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109206 (8-Cyano-1-cyclopropylmethyl-7-(4-methoxy-phenyl)-6...) Show SMILES CCOC(=O)c1cn(CC2CC2)c2c(C#N)c(c(CN(C)CCc3ccccn3)n2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C31H33N5O4/c1-4-40-31(38)26-19-35(18-21-8-9-21)29-25(17-32)28(22-10-12-24(39-3)13-11-22)27(36(29)30(26)37)20-34(2)16-14-23-7-5-6-15-33-23/h5-7,10-13,15,19,21H,4,8-9,14,16,18,20H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109202 (8-Cyano-1-(2,4-difluoro-benzyl)-7-(4-isobutoxy-phe...) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2F)c2c(C#N)c(c(CN(C)CCc3ccncc3)n2c1=O)-c1ccc(OCC(C)C)cc1 Show InChI InChI=1S/C37H37F2N5O4/c1-5-47-37(46)31-21-43(20-27-6-9-28(38)18-32(27)39)35-30(19-40)34(26-7-10-29(11-8-26)48-23-24(2)3)33(44(35)36(31)45)22-42(4)17-14-25-12-15-41-16-13-25/h6-13,15-16,18,21,24H,5,14,17,20,22-23H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human GnRH receptor of the compound using des-Gly10[125I-Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligand				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109219 (4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...) Show SMILES Cc1cc(cc(C)c1C)-c1c(OCC[C@@H]2CCN2)c2cc(ccc2[nH]c1=O)C(=O)Nc1ccncn1 Show InChI InChI=1S/C28H29N5O3/c1-16-12-20(13-17(2)18(16)3)25-26(36-11-8-21-6-10-30-21)22-14-19(4-5-23(22)32-28(25)35)27(34)33-24-7-9-29-15-31-24/h4-5,7,9,12-15,21,30H,6,8,10-11H2,1-3H3,(H,32,35)(H,29,31,33,34)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human GnRH receptor of the compound using des-Gly10[125I-Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligand				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50109219 (4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...) Show SMILES Cc1cc(cc(C)c1C)-c1c(OCC[C@@H]2CCN2)c2cc(ccc2[nH]c1=O)C(=O)Nc1ccncn1 Show InChI InChI=1S/C28H29N5O3/c1-16-12-20(13-17(2)18(16)3)25-26(36-11-8-21-6-10-30-21)22-14-19(4-5-23(22)32-28(25)35)27(34)33-24-7-9-29-15-31-24/h4-5,7,9,12-15,21,30H,6,8,10-11H2,1-3H3,(H,32,35)(H,29,31,33,34)/t21-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50099023 (CHEMBL11149 | N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C29H35N3O2S/c1-21-18-22(2)20-24(19-21)29-27(26-9-4-5-10-28(26)31-29)15-17-30-16-7-6-8-23-11-13-25(14-12-23)32-35(3,33)34/h4-5,9-14,18-20,30-32H,6-8,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human GnRH receptor of the compound using des-Gly10[125I-Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligand				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50099023 (CHEMBL11149 | N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C29H35N3O2S/c1-21-18-22(2)20-24(19-21)29-27(26-9-4-5-10-28(26)31-29)15-17-30-16-7-6-8-23-11-13-25(14-12-23)32-35(3,33)34/h4-5,9-14,18-20,30-32H,6-8,15-17H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
					More data for this Ligand-Target Pair