Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50084617 (((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50097771 (3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPER...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50110746 (3-Carbamimidoyl-N-{2-[4-(4-chloro-phenyl)-piperazi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa(fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50110748 ((3-Carbamimidoyl-benzoylamino)-phenyl-acetic acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50110745 (3-(6-Carbamimidoyl-naphthalen-2-yl)-2-{4-[1-(1-imi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50084617 (((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 159 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50110749 (CHEMBL417827 | N-{[(4-Aminomethyl-cyclohexylmethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50110745 (3-(6-Carbamimidoyl-naphthalen-2-yl)-2-{4-[1-(1-imi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50097771 (3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPER...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB PubMed | 980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50110746 (3-Carbamimidoyl-N-{2-[4-(4-chloro-phenyl)-piperazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against thrombin. | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50110748 ((3-Carbamimidoyl-benzoylamino)-phenyl-acetic acid ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50110746 (3-Carbamimidoyl-N-{2-[4-(4-chloro-phenyl)-piperazi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50110745 (3-(6-Carbamimidoyl-naphthalen-2-yl)-2-{4-[1-(1-imi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against thrombin. | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50110747 (2-(3-Carbamimidoyl-benzoylamino)-3-naphthalen-2-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor Xa (fXa) | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50110749 (CHEMBL417827 | N-{[(4-Aminomethyl-cyclohexylmethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50110748 ((3-Carbamimidoyl-benzoylamino)-phenyl-acetic acid ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against thrombin. | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50084617 (((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against thrombin. | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50110747 (2-(3-Carbamimidoyl-benzoylamino)-3-naphthalen-2-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50097774 (CHEMBL20912 | N-{[(4-Aminomethyl-cyclohexylmethyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Protherics Molecular Design Curated by ChEMBL | Assay Description Inhibitory concentration against bovine trypsin | J Med Chem 45: 1221-32 (2002) BindingDB Entry DOI: 10.7270/Q2319V5W | |||||||||||
More data for this Ligand-Target Pair |