Compile Data Set for Download or QSAR

Found 85 hits Enz. Inhib. hit(s) with all data for entry = 50015232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153217 (CHEMBL425359 | N-(2-Diethylamino-ethyl)-4-[3-(4-tr...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H25F3N4O2/c1-3-28(4-2)14-13-25-19(29)15-5-9-17(10-6-15)26-20(30)27-18-11-7-16(8-12-18)21(22,23)24/h5-12H,3-4,13-14H2,1-2H3,(H,25,29)(H2,26,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153220 (2-Methoxy-4-[3-(3-phenylamino-phenyl)-ureido]-N-(3...) Show SMILES COc1cc(NC(=O)Nc2cccc(Nc3ccccc3)c2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H35N5O3/c1-37-27-21-25(14-15-26(27)28(35)30-16-9-19-34-17-6-3-7-18-34)33-29(36)32-24-13-8-12-23(20-24)31-22-10-4-2-5-11-22/h2,4-5,8,10-15,20-21,31H,3,6-7,9,16-19H2,1H3,(H,30,35)(H2,32,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153232 (2-Methoxy-4-[3-(3-phenoxy-phenyl)-ureido]-N-(3-pip...) Show SMILES COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(14-15-26(27)28(34)30-16-9-19-33-17-6-3-7-18-33)32-29(35)31-22-10-8-13-25(20-22)37-24-11-4-2-5-12-24/h2,4-5,8,10-15,20-21H,3,6-7,9,16-19H2,1H3,(H,30,34)(H2,31,32,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153203 (CHEMBL187854 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1OC Show InChI InChI=1S/C22H27F3N4O3/c1-4-29(5-2)13-12-26-20(30)18-11-10-17(14-19(18)32-3)28-21(31)27-16-8-6-15(7-9-16)22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153220 (2-Methoxy-4-[3-(3-phenylamino-phenyl)-ureido]-N-(3...) Show SMILES COc1cc(NC(=O)Nc2cccc(Nc3ccccc3)c2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H35N5O3/c1-37-27-21-25(14-15-26(27)28(35)30-16-9-19-34-17-6-3-7-18-34)33-29(36)32-24-13-8-12-23(20-24)31-22-10-4-2-5-11-22/h2,4-5,8,10-15,20-21,31H,3,6-7,9,16-19H2,1H3,(H,30,35)(H2,32,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153232 (2-Methoxy-4-[3-(3-phenoxy-phenyl)-ureido]-N-(3-pip...) Show SMILES COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(14-15-26(27)28(34)30-16-9-19-33-17-6-3-7-18-33)32-29(35)31-22-10-8-13-25(20-22)37-24-11-4-2-5-12-24/h2,4-5,8,10-15,20-21H,3,6-7,9,16-19H2,1H3,(H,30,34)(H2,31,32,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153206 (2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...) Show SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153203 (CHEMBL187854 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1OC Show InChI InChI=1S/C22H27F3N4O3/c1-4-29(5-2)13-12-26-20(30)18-11-10-17(14-19(18)32-3)28-21(31)27-16-8-6-15(7-9-16)22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153209 (CHEMBL365055 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1OC Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153223 (CHEMBL184634 | N-(2-Diethylamino-ethyl)-4-[3-(4-tr...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C21H25F3N4O3/c1-3-28(4-2)14-13-25-19(29)15-5-7-16(8-6-15)26-20(30)27-17-9-11-18(12-10-17)31-21(22,23)24/h5-12H,3-4,13-14H2,1-2H3,(H,25,29)(H2,26,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153199 (2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phen...) Show SMILES COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)NCCCN1CCOCC1 Show InChI InChI=1S/C28H32N4O5/c1-35-26-20-22(11-12-25(26)27(33)29-13-6-14-32-15-17-36-18-16-32)31-28(34)30-21-7-5-10-24(19-21)37-23-8-3-2-4-9-23/h2-5,7-12,19-20H,6,13-18H2,1H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153199 (2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phen...) Show SMILES COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)NCCCN1CCOCC1 Show InChI InChI=1S/C28H32N4O5/c1-35-26-20-22(11-12-25(26)27(33)29-13-6-14-32-15-17-36-18-16-32)31-28(34)30-21-7-5-10-24(19-21)37-23-8-3-2-4-9-23/h2-5,7-12,19-20H,6,13-18H2,1H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153198 (Biphenyl-4-carboxylic acid [4-(1-benzyl-piperidin-...) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C33H33N3O3/c1-39-31-22-29(35-32(37)27-14-12-26(13-15-27)25-10-6-3-7-11-25)16-17-30(31)33(38)34-28-18-20-36(21-19-28)23-24-8-4-2-5-9-24/h2-17,22,28H,18-21,23H2,1H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153215 (CHEMBL184560 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1OC Show InChI InChI=1S/C27H32N4O4/c1-4-31(5-2)18-17-28-26(32)24-16-13-21(19-25(24)34-3)30-27(33)29-20-11-14-23(15-12-20)35-22-9-7-6-8-10-22/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153204 (CHEMBL186894 | N-[2-(4-Benzyl-piperazin-1-yl)-ethy...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc(cc1)C(=O)NCCN1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C33H35N5O3/c39-32(34-19-20-37-21-23-38(24-22-37)25-26-7-3-1-4-8-26)27-11-13-28(14-12-27)35-33(40)36-29-15-17-31(18-16-29)41-30-9-5-2-6-10-30/h1-18H,19-25H2,(H,34,39)(H2,35,36,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153209 (CHEMBL365055 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1OC Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153203 (CHEMBL187854 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1OC Show InChI InChI=1S/C22H27F3N4O3/c1-4-29(5-2)13-12-26-20(30)18-11-10-17(14-19(18)32-3)28-21(31)27-16-8-6-15(7-9-16)22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153217 (CHEMBL425359 | N-(2-Diethylamino-ethyl)-4-[3-(4-tr...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H25F3N4O2/c1-3-28(4-2)14-13-25-19(29)15-5-9-17(10-6-15)26-20(30)27-18-11-7-16(8-12-18)21(22,23)24/h5-12H,3-4,13-14H2,1-2H3,(H,25,29)(H2,26,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153218 (CHEMBL184585 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(SC(F)(F)F)cc2)cc1OC Show InChI InChI=1S/C22H27F3N4O3S/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153213 (CHEMBL188179 | N-(2-Diethylamino-ethyl)-2-ethoxy-4...) Show SMILES CCOc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCN(CC)CC Show InChI InChI=1S/C28H34N4O4/c1-4-32(5-2)19-18-29-27(33)25-17-14-22(20-26(25)35-6-3)31-28(34)30-21-12-15-24(16-13-21)36-23-10-8-7-9-11-23/h7-17,20H,4-6,18-19H2,1-3H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153206 (2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-pip...) Show SMILES COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153226 (4-[3-(4-Bromo-phenyl)-ureido]-N-(2-diethylamino-et...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(Br)cc2)cc1OC Show InChI InChI=1S/C21H27BrN4O3/c1-4-26(5-2)13-12-23-20(27)18-11-10-17(14-19(18)29-3)25-21(28)24-16-8-6-15(22)7-9-16/h6-11,14H,4-5,12-13H2,1-3H3,(H,23,27)(H2,24,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153223 (CHEMBL184634 | N-(2-Diethylamino-ethyl)-4-[3-(4-tr...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C21H25F3N4O3/c1-3-28(4-2)14-13-25-19(29)15-5-7-16(8-6-15)26-20(30)27-17-9-11-18(12-10-17)31-21(22,23)24/h5-12H,3-4,13-14H2,1-2H3,(H,25,29)(H2,26,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153210 (CHEMBL184292 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H30N4O3/c1-2-31-18-6-7-23(31)19-28-26(32)20-10-12-21(13-11-20)29-27(33)30-22-14-16-25(17-15-22)34-24-8-4-3-5-9-24/h3-5,8-17,23H,2,6-7,18-19H2,1H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153209 (CHEMBL365055 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1OC Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153244 (Biphenyl-4-carboxylic acid [4-(2-diethylamino-ethy...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cc1OC Show InChI InChI=1S/C27H31N3O3/c1-4-30(5-2)18-17-28-27(32)24-16-15-23(19-25(24)33-3)29-26(31)22-13-11-21(12-14-22)20-9-7-6-8-10-20/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153222 (CHEMBL182913 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1OC Show InChI InChI=1S/C28H32N4O4/c1-3-32-17-7-8-22(32)19-29-27(33)25-16-13-21(18-26(25)35-2)31-28(34)30-20-11-14-24(15-12-20)36-23-9-5-4-6-10-23/h4-6,9-16,18,22H,3,7-8,17,19H2,1-2H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153242 (CHEMBL187850 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1OC)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H34N4O4/c1-5-32(6-2)19-18-29-27(33)25-17-14-22(20-26(25)35-4)31(3)28(34)30-21-12-15-24(16-13-21)36-23-10-8-7-9-11-23/h7-17,20H,5-6,18-19H2,1-4H3,(H,29,33)(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153200 (Biphenyl-4-carboxylic acid [4-(3-dimethylamino-pro...) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1C(=O)NCCCN(C)C Show InChI InChI=1S/C26H29N3O3/c1-29(2)17-7-16-27-26(31)23-15-14-22(18-24(23)32-3)28-25(30)21-12-10-20(11-13-21)19-8-5-4-6-9-19/h4-6,8-15,18H,7,16-17H2,1-3H3,(H,27,31)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153205 (Biphenyl-4-carboxylic acid {4-[2-(4-benzyl-piperaz...) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1C(=O)NCCN1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C34H36N4O3/c1-41-32-24-30(36-33(39)29-14-12-28(13-15-29)27-10-6-3-7-11-27)16-17-31(32)34(40)35-18-19-37-20-22-38(23-21-37)25-26-8-4-2-5-9-26/h2-17,24H,18-23,25H2,1H3,(H,35,40)(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153219 (4-[3-(3,4-Dichloro-phenyl)-ureido]-N-(2-diethylami...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1OC Show InChI InChI=1S/C21H26Cl2N4O3/c1-4-27(5-2)11-10-24-20(28)16-8-6-15(13-19(16)30-3)26-21(29)25-14-7-9-17(22)18(23)12-14/h6-9,12-13H,4-5,10-11H2,1-3H3,(H,24,28)(H2,25,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153215 (CHEMBL184560 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1OC Show InChI InChI=1S/C27H32N4O4/c1-4-31(5-2)18-17-28-26(32)24-16-13-21(19-25(24)34-3)30-27(33)29-20-11-14-23(15-12-20)35-22-9-7-6-8-10-22/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153224 (2-Methoxy-4-[3-(4-phenylamino-phenyl)-ureido]-N-(3...) Show SMILES COc1cc(NC(=O)Nc2ccc(Nc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H35N5O3/c1-37-27-21-25(15-16-26(27)28(35)30-17-8-20-34-18-6-3-7-19-34)33-29(36)32-24-13-11-23(12-14-24)31-22-9-4-2-5-10-22/h2,4-5,9-16,21,31H,3,6-8,17-20H2,1H3,(H,30,35)(H2,32,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153215 (CHEMBL184560 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1OC Show InChI InChI=1S/C27H32N4O4/c1-4-31(5-2)18-17-28-26(32)24-16-13-21(19-25(24)34-3)30-27(33)29-20-11-14-23(15-12-20)35-22-9-7-6-8-10-22/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153225 (CHEMBL365011 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(SC)cc2)cc1OC Show InChI InChI=1S/C22H30N4O3S/c1-5-26(6-2)14-13-23-21(27)19-12-9-17(15-20(19)29-3)25-22(28)24-16-7-10-18(30-4)11-8-16/h7-12,15H,5-6,13-14H2,1-4H3,(H,23,27)(H2,24,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153210 (CHEMBL184292 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H30N4O3/c1-2-31-18-6-7-23(31)19-28-26(32)20-10-12-21(13-11-20)29-27(33)30-22-14-16-25(17-15-22)34-24-8-4-3-5-9-24/h3-5,8-17,23H,2,6-7,18-19H2,1H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153224 (2-Methoxy-4-[3-(4-phenylamino-phenyl)-ureido]-N-(3...) Show SMILES COc1cc(NC(=O)Nc2ccc(Nc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C29H35N5O3/c1-37-27-21-25(15-16-26(27)28(35)30-17-8-20-34-18-6-3-7-19-34)33-29(36)32-24-13-11-23(12-14-24)31-22-9-4-2-5-10-22/h2,4-5,9-16,21,31H,3,6-8,17-20H2,1H3,(H,30,35)(H2,32,33,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153207 (4-(3-Biphenyl-4-yl-ureido)-N-(3-dimethylamino-prop...) Show SMILES COc1cc(NC(=O)Nc2ccc(cc2)-c2ccccc2)ccc1C(=O)NCCCN(C)C Show InChI InChI=1S/C26H30N4O3/c1-30(2)17-7-16-27-25(31)23-15-14-22(18-24(23)33-3)29-26(32)28-21-12-10-20(11-13-21)19-8-5-4-6-9-19/h4-6,8-15,18H,7,16-17H2,1-3H3,(H,27,31)(H2,28,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153216 (CHEMBL363264 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(cc1)-c1noc(n1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C28H28N4O3/c1-2-32-18-6-7-23(32)19-29-27(33)21-12-10-20(11-13-21)26-30-28(35-31-26)22-14-16-25(17-15-22)34-24-8-4-3-5-9-24/h3-5,8-17,23H,2,6-7,18-19H2,1H3,(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153211 (CHEMBL185348 | N-(3-Dimethylamino-propyl)-2-methox...) Show SMILES COc1cc(NC(=O)c2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN(C)C Show InChI InChI=1S/C26H29N3O4/c1-29(2)17-7-16-27-26(31)23-15-12-20(18-24(23)32-3)28-25(30)19-10-13-22(14-11-19)33-21-8-5-4-6-9-21/h4-6,8-15,18H,7,16-17H2,1-3H3,(H,27,31)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153213 (CHEMBL188179 | N-(2-Diethylamino-ethyl)-2-ethoxy-4...) Show SMILES CCOc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCN(CC)CC Show InChI InChI=1S/C28H34N4O4/c1-4-32(5-2)19-18-29-27(33)25-17-14-22(20-26(25)35-6-3)31-28(34)30-21-12-15-24(16-13-21)36-23-10-8-7-9-11-23/h7-17,20H,4-6,18-19H2,1-3H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153202 (CHEMBL186491 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)c2ccc(Oc3ccccc3)cc2)cc1OC Show InChI InChI=1S/C27H31N3O4/c1-4-30(5-2)18-17-28-27(32)24-16-13-21(19-25(24)33-3)29-26(31)20-11-14-23(15-12-20)34-22-9-7-6-8-10-22/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153228 (Biphenyl-4-carboxylic acid [4-(2-dimethylamino-eth...) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1C(=O)NCCN(C)C Show InChI InChI=1S/C25H27N3O3/c1-28(2)16-15-26-25(30)22-14-13-21(17-23(22)31-3)27-24(29)20-11-9-19(10-12-20)18-7-5-4-6-8-18/h4-14,17H,15-16H2,1-3H3,(H,26,30)(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153197 (CHEMBL184528 | N-(2-Diethylamino-ethyl)-4-[5-(4-ph...) Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1)-c1noc(n1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H28N4O3/c1-3-31(4-2)19-18-28-26(32)21-12-10-20(11-13-21)25-29-27(34-30-25)22-14-16-24(17-15-22)33-23-8-6-5-7-9-23/h5-17H,3-4,18-19H2,1-2H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153240 (CHEMBL184418 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2cccc(OC(F)(F)F)c2)cc1OC Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)12-11-26-20(30)18-10-9-16(14-19(18)32-3)28-21(31)27-15-7-6-8-17(13-15)33-22(23,24)25/h6-10,13-14H,4-5,11-12H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50153204 (CHEMBL186894 | N-[2-(4-Benzyl-piperazin-1-yl)-ethy...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc(cc1)C(=O)NCCN1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C33H35N5O3/c39-32(34-19-20-37-21-23-38(24-22-37)25-26-7-3-1-4-8-26)27-11-13-28(14-12-27)35-33(40)36-29-15-17-31(18-16-29)41-30-9-5-2-6-10-30/h1-18H,19-25H2,(H,34,39)(H2,35,36,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153237 (4-[3-(4-Cyano-phenyl)-ureido]-N-(2-diethylamino-et...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C#N)cc1OC Show InChI InChI=1S/C22H27N5O3/c1-4-27(5-2)13-12-24-21(28)19-11-10-18(14-20(19)30-3)26-22(29)25-17-8-6-16(15-23)7-9-17/h6-11,14H,4-5,12-13H2,1-3H3,(H,24,28)(H2,25,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153222 (CHEMBL182913 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1OC Show InChI InChI=1S/C28H32N4O4/c1-3-32-17-7-8-22(32)19-29-27(33)25-16-13-21(18-26(25)35-2)31-28(34)30-20-11-14-24(15-12-20)36-23-9-5-4-6-10-23/h4-6,9-16,18,22H,3,7-8,17,19H2,1-2H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153201 (CHEMBL181492 | N-(2-Diethylamino-ethyl)-4-[3-(4-ph...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O3/c1-3-30(4-2)19-18-27-25(31)20-10-12-21(13-11-20)28-26(32)29-22-14-16-24(17-15-22)33-23-8-6-5-7-9-23/h5-17H,3-4,18-19H2,1-2H3,(H,27,31)(H2,28,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153235 (4-[3-(3-Chloro-4-fluoro-phenyl)-ureido]-N-(2-dieth...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(F)c(Cl)c2)cc1OC Show InChI InChI=1S/C21H26ClFN4O3/c1-4-27(5-2)11-10-24-20(28)16-8-6-15(13-19(16)30-3)26-21(29)25-14-7-9-18(23)17(22)12-14/h6-9,12-13H,4-5,10-11H2,1-3H3,(H,24,28)(H2,25,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair

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