BDBM50153210 CHEMBL184292::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4-[3-(4-phenoxy-phenyl)-ureido]-benzamide

SMILES: CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1

InChI Key: InChIKey=QWMKDONQFULFHL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50153210 (CHEMBL184292 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H30N4O3/c1-2-31-18-6-7-23(31)19-28-26(32)20-10-12-21(13-11-20)29-27(33)30-22-14-16-25(17-15-22)34-24-8-4-3-5-9-24/h3-5,8-17,23H,2,6-7,18-19H2,1H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50153210 (CHEMBL184292 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H30N4O3/c1-2-31-18-6-7-23(31)19-28-26(32)20-10-12-21(13-11-20)29-27(33)30-22-14-16-25(17-15-22)34-24-8-4-3-5-9-24/h3-5,8-17,23H,2,6-7,18-19H2,1H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
GPR145 (Homo sapiens (Human))	BDBM50153210 (CHEMBL184292 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-4...) Show SMILES CCN1CCCC1CNC(=O)c1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H30N4O3/c1-2-31-18-6-7-23(31)19-28-26(32)20-10-12-21(13-11-20)29-27(33)30-22-14-16-25(17-15-22)34-24-8-4-3-5-9-24/h3-5,8-17,23H,2,6-7,18-19H2,1H3,(H,28,32)(H2,29,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair