Found 146 hits Enz. Inhib. hit(s) with all data for entry = 50020270 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212000
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211981
(CHEMBL236420 | N-(4-isopropylphenyl)-1-(2-(pyridin...)Show InChI InChI=1S/C20H22N4O/c1-15(2)17-3-5-18(6-4-17)23-20(25)19-9-13-22-24(19)14-10-16-7-11-21-12-8-16/h3-9,11-13,15H,10,14H2,1-2H3,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212000
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211981
(CHEMBL236420 | N-(4-isopropylphenyl)-1-(2-(pyridin...)Show InChI InChI=1S/C20H22N4O/c1-15(2)17-3-5-18(6-4-17)23-20(25)19-9-13-22-24(19)14-10-16-7-11-21-12-8-16/h3-9,11-13,15H,10,14H2,1-2H3,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212010
(CHEMBL392935 | N-(4-ethylphenyl)-1-(2-(pyridin-4-y...)Show InChI InChI=1S/C19H20N4O/c1-2-15-3-5-17(6-4-15)22-19(24)18-9-13-21-23(18)14-10-16-7-11-20-12-8-16/h3-9,11-13H,2,10,14H2,1H3,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211970
(CHEMBL234009 | N-(3,4-dimethoxyphenyl)-1-(2-(pyrid...)Show InChI InChI=1S/C19H20N4O3/c1-25-17-4-3-15(13-18(17)26-2)22-19(24)16-7-11-21-23(16)12-8-14-5-9-20-10-6-14/h3-7,9-11,13H,8,12H2,1-2H3,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211990
(CHEMBL392330 | N-(3,4-dichlorophenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C17H14Cl2N4O/c18-14-2-1-13(11-15(14)19)22-17(24)16-5-9-21-23(16)10-6-12-3-7-20-8-4-12/h1-5,7-9,11H,6,10H2,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212010
(CHEMBL392935 | N-(4-ethylphenyl)-1-(2-(pyridin-4-y...)Show InChI InChI=1S/C19H20N4O/c1-2-15-3-5-17(6-4-15)22-19(24)18-9-13-21-23(18)14-10-16-7-11-20-12-8-16/h3-9,11-13H,2,10,14H2,1H3,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211980
(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)Show InChI InChI=1S/C20H17N5O/c26-20(24-17-13-16-3-1-2-4-18(16)22-14-17)19-7-11-23-25(19)12-8-15-5-9-21-10-6-15/h1-7,9-11,13-14H,8,12H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212010
(CHEMBL392935 | N-(4-ethylphenyl)-1-(2-(pyridin-4-y...)Show InChI InChI=1S/C19H20N4O/c1-2-15-3-5-17(6-4-15)22-19(24)18-9-13-21-23(18)14-10-16-7-11-20-12-8-16/h3-9,11-13H,2,10,14H2,1H3,(H,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211990
(CHEMBL392330 | N-(3,4-dichlorophenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C17H14Cl2N4O/c18-14-2-1-13(11-15(14)19)22-17(24)16-5-9-21-23(16)10-6-12-3-7-20-8-4-12/h1-5,7-9,11H,6,10H2,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211975
(1-(2-(pyridin-4-yl)ethyl)-N-(3-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211975
(1-(2-(pyridin-4-yl)ethyl)-N-(3-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212000
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212004
(CHEMBL234202 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-20-10-12-22(16)11-7-13-5-8-19-9-6-13/h1-6,8-10,12H,7,11H2,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211980
(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)Show InChI InChI=1S/C20H17N5O/c26-20(24-17-13-16-3-1-2-4-18(16)22-14-17)19-7-11-23-25(19)12-8-15-5-9-21-10-6-15/h1-7,9-11,13-14H,8,12H2,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211970
(CHEMBL234009 | N-(3,4-dimethoxyphenyl)-1-(2-(pyrid...)Show InChI InChI=1S/C19H20N4O3/c1-25-17-4-3-15(13-18(17)26-2)22-19(24)16-7-11-21-23(16)12-8-14-5-9-20-10-6-14/h3-7,9-11,13H,8,12H2,1-2H3,(H,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211981
(CHEMBL236420 | N-(4-isopropylphenyl)-1-(2-(pyridin...)Show InChI InChI=1S/C20H22N4O/c1-15(2)17-3-5-18(6-4-17)23-20(25)19-9-13-22-24(19)14-10-16-7-11-21-12-8-16/h3-9,11-13,15H,10,14H2,1-2H3,(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211991
(CHEMBL233822 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1cc(NC(=O)c2ccnn2CCc2ccncc2)ccc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-2-1-13(11-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211975
(1-(2-(pyridin-4-yl)ethyl)-N-(3-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211971
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211988
(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C15H13ClN6O/c16-12-1-3-13(4-2-12)18-15(23)14-19-20-21-22(14)10-7-11-5-8-17-9-6-11/h1-6,8-9H,7,10H2,(H,18,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211991
(CHEMBL233822 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1cc(NC(=O)c2ccnn2CCc2ccncc2)ccc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-2-1-13(11-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211982
(CHEMBL234010 | N-(4-chlorophenyl)-3-methyl-1-(2-(p...)Show InChI InChI=1S/C18H17ClN4O/c1-13-12-17(18(24)21-16-4-2-15(19)3-5-16)23(22-13)11-8-14-6-9-20-10-7-14/h2-7,9-10,12H,8,11H2,1H3,(H,21,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211971
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211967
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212007
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)12-1-3-13(4-2-12)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042 BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this Ligand-Target Pair | |