Compile Data Set for Download or QSAR

Found 37 hits Enz. Inhib. hit(s) with all data for entry = 50021715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227099 (2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)cc(OCC)c1N Show InChI InChI=1S/C23H31N5O5S/c1-3-31-20-11-15(12-21(22(20)24)32-4-2)14-28-9-7-16(8-10-28)26-23-27-18-13-17(34(25,29)30)5-6-19(18)33-23/h5-6,11-13,16H,3-4,7-10,14,24H2,1-2H3,(H,26,27)(H2,25,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227100 (2-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-ylamino)...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)ccc1Cl Show InChI InChI=1S/C21H25ClN4O4S/c1-2-29-20-11-14(3-5-17(20)22)13-26-9-7-15(8-10-26)24-21-25-18-12-16(31(23,27)28)4-6-19(18)30-21/h3-6,11-12,15H,2,7-10,13H2,1H3,(H,24,25)(H2,23,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227119 (CHEMBL236588 | N-(1-(3-isobutoxy-4-methoxybenzyl)p...) Show SMILES COc1ccc(CN2CCC(CC2)Nc2nc3ccccc3o2)cc1OCC(C)C Show InChI InChI=1S/C24H31N3O3/c1-17(2)16-29-23-14-18(8-9-22(23)28-3)15-27-12-10-19(11-13-27)25-24-26-20-6-4-5-7-21(20)30-24/h4-9,14,17,19H,10-13,15-16H2,1-3H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227117 (CHEMBL236611 | N-(1-(3-ethoxy-4-methylbenzyl)piper...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1C Show InChI InChI=1S/C22H27N3O2/c1-3-26-21-14-17(9-8-16(21)2)15-25-12-10-18(11-13-25)23-22-24-19-6-4-5-7-20(19)27-22/h4-9,14,18H,3,10-13,15H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227106 (4-((4-(benzo[d]oxazol-2-ylamino)piperidin-1-yl)met...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1O Show InChI InChI=1S/C21H25N3O3/c1-2-26-20-13-15(7-8-18(20)25)14-24-11-9-16(10-12-24)22-21-23-17-5-3-4-6-19(17)27-21/h3-8,13,16,25H,2,9-12,14H2,1H3,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227109 (CHEMBL393333 | N-(1-(3-(cyclopentyloxy)-4-methoxyb...) Show SMILES COc1ccc(CN2CCC(CC2)Nc2nc3ccccc3o2)cc1OC1CCCC1 Show InChI InChI=1S/C25H31N3O3/c1-29-23-11-10-18(16-24(23)30-20-6-2-3-7-20)17-28-14-12-19(13-15-28)26-25-27-21-8-4-5-9-22(21)31-25/h4-5,8-11,16,19-20H,2-3,6-7,12-15,17H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227112 (CHEMBL236610 | N-(1-(4-chloro-3-ethoxybenzyl)piper...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1Cl Show InChI InChI=1S/C21H24ClN3O2/c1-2-26-20-13-15(7-8-17(20)22)14-25-11-9-16(10-12-25)23-21-24-18-5-3-4-6-19(18)27-21/h3-8,13,16H,2,9-12,14H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227111 (CHEMBL236587 | N-(1-(3-ethoxy-4-methoxybenzyl)pipe...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1OC Show InChI InChI=1S/C22H27N3O3/c1-3-27-21-14-16(8-9-20(21)26-2)15-25-12-10-17(11-13-25)23-22-24-18-6-4-5-7-19(18)28-22/h4-9,14,17H,3,10-13,15H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227116 (4-((4-(benzo[d]thiazol-2-ylamino)piperidin-1-yl)me...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3s2)ccc1O Show InChI InChI=1S/C21H25N3O2S/c1-2-26-19-13-15(7-8-18(19)25)14-24-11-9-16(10-12-24)22-21-23-17-5-3-4-6-20(17)27-21/h3-8,13,16,25H,2,9-12,14H2,1H3,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227107 (2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)ccc1OC Show InChI InChI=1S/C22H28N4O5S/c1-3-30-21-12-15(4-6-20(21)29-2)14-26-10-8-16(9-11-26)24-22-25-18-13-17(32(23,27)28)5-7-19(18)31-22/h4-7,12-13,16H,3,8-11,14H2,1-2H3,(H,24,25)(H2,23,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227114 (CHEMBL393436 | N-(1-(3-ethoxy-4-fluorobenzyl)piper...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1F Show InChI InChI=1S/C21H24FN3O2/c1-2-26-20-13-15(7-8-17(20)22)14-25-11-9-16(10-12-25)23-21-24-18-5-3-4-6-19(18)27-21/h3-8,13,16H,2,9-12,14H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	194	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227105 (CHEMBL391951 | N-(1-(4-methoxy-3-propoxybenzyl)pip...) Show SMILES CCCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1OC Show InChI InChI=1S/C23H29N3O3/c1-3-14-28-22-15-17(8-9-21(22)27-2)16-26-12-10-18(11-13-26)24-23-25-19-6-4-5-7-20(19)29-23/h4-9,15,18H,3,10-14,16H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	293	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227103 (CHEMBL238057 | N-(1-(3-ethoxy-4-methoxybenzyl)pipe...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3s2)ccc1OC Show InChI InChI=1S/C22H27N3O2S/c1-3-27-20-14-16(8-9-19(20)26-2)15-25-12-10-17(11-13-25)23-22-24-18-6-4-5-7-21(18)28-22/h4-9,14,17H,3,10-13,15H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	326	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227115 (CHEMBL236612 | N-(1-(3-ethoxy-4-(trifluoromethoxy)...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1OC(F)(F)F Show InChI InChI=1S/C22H24F3N3O3/c1-2-29-20-13-15(7-8-19(20)31-22(23,24)25)14-28-11-9-16(10-12-28)26-21-27-17-5-3-4-6-18(17)30-21/h3-8,13,16H,2,9-12,14H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	524	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50227111 (CHEMBL236587 | N-(1-(3-ethoxy-4-methoxybenzyl)pipe...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1OC Show InChI InChI=1S/C22H27N3O3/c1-3-27-21-14-16(8-9-20(21)26-2)15-25-12-10-17(11-13-25)23-22-24-18-6-4-5-7-19(18)28-22/h4-9,14,17H,3,10-13,15H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	624	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Binding affinity to histamine H1 receptor				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227125 (CHEMBL237865 | N-(1-((1,4-dimethoxynaphthalen-2-yl...) Show SMILES COc1cc(CN2CCC(CC2)Nc2nc3ccccc3s2)c(OC)c2ccccc12 Show InChI InChI=1S/C25H27N3O2S/c1-29-22-15-17(24(30-2)20-8-4-3-7-19(20)22)16-28-13-11-18(12-14-28)26-25-27-21-9-5-6-10-23(21)31-25/h3-10,15,18H,11-14,16H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	683	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227120 (CHEMBL238058 | N-(1-((1,4-dimethoxynaphthalen-2-yl...) Show SMILES COc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)c(OC)c2ccccc12 Show InChI InChI=1S/C25H27N3O3/c1-29-23-15-17(24(30-2)20-8-4-3-7-19(20)23)16-28-13-11-18(12-14-28)26-25-27-21-9-5-6-10-22(21)31-25/h3-10,15,18H,11-14,16H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227124 (1-(4-fluorobenzyl)-N-(1-((1,4-dimethoxynaphthalen-...) Show SMILES COc1cc(CN2CCC(CC2)Nc2nc3ccccc3n2Cc2ccc(F)cc2)c(OC)c2ccccc12 Show InChI InChI=1S/C32H33FN4O2/c1-38-30-19-23(31(39-2)27-8-4-3-7-26(27)30)21-36-17-15-25(16-18-36)34-32-35-28-9-5-6-10-29(28)37(32)20-22-11-13-24(33)14-12-22/h3-14,19,25H,15-18,20-21H2,1-2H3,(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227127 (1-(4-fluorobenzyl)-N-(1-((7-methyl-1H-indol-3-yl)m...) Show SMILES Cc1cccc2c(CN3CCC(CC3)Nc3nc4ccccc4n3Cc3ccc(F)cc3)c[nH]c12 Show InChI InChI=1S/C29H30FN5/c1-20-5-4-6-25-22(17-31-28(20)25)19-34-15-13-24(14-16-34)32-29-33-26-7-2-3-8-27(26)35(29)18-21-9-11-23(30)12-10-21/h2-12,17,24,31H,13-16,18-19H2,1H3,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227110 (1-(4-fluorobenzyl)-N-(1-((2,3-dihydrobenzofuran-5-...) Show SMILES Fc1ccc(Cn2c(NC3CCN(Cc4ccc5OCCc5c4)CC3)nc3ccccc23)cc1 Show InChI InChI=1S/C28H29FN4O/c29-23-8-5-20(6-9-23)19-33-26-4-2-1-3-25(26)31-28(33)30-24-11-14-32(15-12-24)18-21-7-10-27-22(17-21)13-16-34-27/h1-10,17,24H,11-16,18-19H2,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227121 (CHEMBL391950 | N-(1-(3,4-dimethoxybenzyl)piperidin...) Show SMILES COc1ccc(CN2CCC(CC2)Nc2nc3ccccc3s2)cc1OC Show InChI InChI=1S/C21H25N3O2S/c1-25-18-8-7-15(13-19(18)26-2)14-24-11-9-16(10-12-24)22-21-23-17-5-3-4-6-20(17)27-21/h3-8,13,16H,9-12,14H2,1-2H3,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227101 (CHEMBL236787 | N-(1-((1H-indol-5-yl)methyl)piperid...) Show SMILES Fc1ccc(Cn2c(NC3CCN(Cc4ccc5[nH]ccc5c4)CC3)nc3ccccc23)cc1 Show InChI InChI=1S/C28H28FN5/c29-23-8-5-20(6-9-23)19-34-27-4-2-1-3-26(27)32-28(34)31-24-12-15-33(16-13-24)18-21-7-10-25-22(17-21)11-14-30-25/h1-11,14,17,24,30H,12-13,15-16,18-19H2,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227104 (1-(4-fluorobenzyl)-N-(1-(4-methoxybenzyl)piperidin...) Show SMILES COc1ccc(CN2CCC(CC2)Nc2nc3ccccc3n2Cc2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H29FN4O/c1-33-24-12-8-20(9-13-24)18-31-16-14-23(15-17-31)29-27-30-25-4-2-3-5-26(25)32(27)19-21-6-10-22(28)11-7-21/h2-13,23H,14-19H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM24226 (1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxypheny...) Show SMILES COc1ccc(CCN2CCC(CC2)Nc2nc3ccccc3n2Cc2ccc(F)cc2)cc1 Show InChI InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227122 (1-(4-fluorobenzyl)-N-(1-phenethylpiperidin-4-yl)-1...) Show SMILES Fc1ccc(Cn2c(NC3CCN(CCc4ccccc4)CC3)nc3ccccc23)cc1 Show InChI InChI=1S/C27H29FN4/c28-23-12-10-22(11-13-23)20-32-26-9-5-4-8-25(26)30-27(32)29-24-15-18-31(19-16-24)17-14-21-6-2-1-3-7-21/h1-13,24H,14-20H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227126 (4-((4-(benzo[d]thiazol-2-ylamino)piperidin-1-yl)me...) Show SMILES COc1cc(CN2CCC(CC2)Nc2nc3ccccc3s2)ccc1O Show InChI InChI=1S/C20H23N3O2S/c1-25-18-12-14(6-7-17(18)24)13-23-10-8-15(9-11-23)21-20-22-16-4-2-3-5-19(16)26-20/h2-7,12,15,24H,8-11,13H2,1H3,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227102 (1-(4-fluorobenzyl)-N-(1-benzylpiperidin-4-yl)-1H-b...) Show SMILES Fc1ccc(Cn2c(NC3CCN(Cc4ccccc4)CC3)nc3ccccc23)cc1 Show InChI InChI=1S/C26H27FN4/c27-22-12-10-21(11-13-22)19-31-25-9-5-4-8-24(25)29-26(31)28-23-14-16-30(17-15-23)18-20-6-2-1-3-7-20/h1-13,23H,14-19H2,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227118 (1-(4-fluorobenzyl)-N-(1-(4-fluorophenethyl)piperid...) Show SMILES Fc1ccc(CCN2CCC(CC2)Nc2nc3ccccc3n2Cc2ccc(F)cc2)cc1 Show InChI InChI=1S/C27H28F2N4/c28-22-9-5-20(6-10-22)13-16-32-17-14-24(15-18-32)30-27-31-25-3-1-2-4-26(25)33(27)19-21-7-11-23(29)12-8-21/h1-12,24H,13-19H2,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227113 (1-(4-fluorobenzyl)-N-(1-((1,2,3,4-tetrahydronaphth...) Show SMILES Fc1ccc(Cn2c(NC3CCN(CC4CCc5ccccc5C4)CC3)nc3ccccc23)cc1 |w:14.13| Show InChI InChI=1S/C30H33FN4/c31-26-13-10-22(11-14-26)21-35-29-8-4-3-7-28(29)33-30(35)32-27-15-17-34(18-16-27)20-23-9-12-24-5-1-2-6-25(24)19-23/h1-8,10-11,13-14,23,27H,9,12,15-21H2,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227108 (CHEMBL399015 | N-(1-(4-(trifluoromethoxy)phenethyl...) Show SMILES Fc1ccc(Cn2c(NC3CCN(CCc4ccc(OC(F)(F)F)cc4)CC3)nc3ccccc23)cc1 Show InChI InChI=1S/C28H28F4N4O/c29-22-9-5-21(6-10-22)19-36-26-4-2-1-3-25(26)34-27(36)33-23-14-17-35(18-15-23)16-13-20-7-11-24(12-8-20)37-28(30,31)32/h1-12,23H,13-19H2,(H,33,34)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM50227099 (2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)cc(OCC)c1N Show InChI InChI=1S/C23H31N5O5S/c1-3-31-20-11-15(12-21(22(20)24)32-4-2)14-28-9-7-16(8-10-28)26-23-27-18-13-17(34(25,29)30)5-6-19(18)33-23/h5-6,11-13,16H,3-4,7-10,14,24H2,1-2H3,(H,26,27)(H2,25,29,30)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Binding affinity to human SST1R				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50227099 (2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)cc(OCC)c1N Show InChI InChI=1S/C23H31N5O5S/c1-3-31-20-11-15(12-21(22(20)24)32-4-2)14-28-9-7-16(8-10-28)26-23-27-18-13-17(34(25,29)30)5-6-19(18)33-23/h5-6,11-13,16H,3-4,7-10,14,24H2,1-2H3,(H,26,27)(H2,25,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Binding affinity to human SST3R				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50227099 (2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)cc(OCC)c1N Show InChI InChI=1S/C23H31N5O5S/c1-3-31-20-11-15(12-21(22(20)24)32-4-2)14-28-9-7-16(8-10-28)26-23-27-18-13-17(34(25,29)30)5-6-19(18)33-23/h5-6,11-13,16H,3-4,7-10,14,24H2,1-2H3,(H,26,27)(H2,25,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Binding affinity to human SST2R				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50227099 (2-(1-(4-amino-3,5-diethoxybenzyl)piperidin-4-ylami...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)cc(OCC)c1N Show InChI InChI=1S/C23H31N5O5S/c1-3-31-20-11-15(12-21(22(20)24)32-4-2)14-28-9-7-16(8-10-28)26-23-27-18-13-17(34(25,29)30)5-6-19(18)33-23/h5-6,11-13,16H,3-4,7-10,14,24H2,1-2H3,(H,26,27)(H2,25,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Binding affinity to human SST4R				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227123 (1-(4-fluorobenzyl)-N-(1-(3-phenylpropyl)piperidin-...) Show SMILES Fc1ccc(Cn2c(NC3CCN(CCCc4ccccc4)CC3)nc3ccccc23)cc1 Show InChI InChI=1S/C28H31FN4/c29-24-14-12-23(13-15-24)21-33-27-11-5-4-10-26(27)31-28(33)30-25-16-19-32(20-17-25)18-6-9-22-7-2-1-3-8-22/h1-5,7-8,10-15,25H,6,9,16-21H2,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]11-Tyr somatostatin-14 from human SST5R expressed in CHO cells				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50227111 (CHEMBL236587 | N-(1-(3-ethoxy-4-methoxybenzyl)pipe...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)ccc1OC Show InChI InChI=1S/C22H27N3O3/c1-3-27-21-14-16(8-9-20(21)26-2)15-25-12-10-17(11-13-25)23-22-24-18-6-4-5-7-19(18)28-22/h4-9,14,17H,3,10-13,15H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human SST5R expressed in CHO cells assessed as reversal of somatostatin-14 induced cAMP response				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50227107 (2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino...) Show SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(N)(=O)=O)ccc1OC Show InChI InChI=1S/C22H28N4O5S/c1-3-30-21-12-15(4-6-20(21)29-2)14-26-10-8-16(9-11-26)24-22-25-18-13-17(32(23,27)28)5-7-19(18)31-22/h4-7,12-13,16H,3,8-11,14H2,1-2H3,(H,24,25)(H2,23,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of hERG channel				J Med Chem 50: 6291-4 (2007) Article DOI: 10.1021/jm701143p BindingDB Entry DOI: 10.7270/Q2WS8T0K
					More data for this Ligand-Target Pair