Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50342128 (3-Imidazol-1-yl-2-methyl-3-[4-(naphthalen-2-ylamin...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 (unknown origin) | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50377963 (CHEMBL224305 | R-115866) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 (unknown origin) | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120455 (CHEMBL3617993) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 (unknown origin) | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50162789 (CHEMBL180856 | [2-(6-Benzyloxy-naphthalen-2-yl)-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 (unknown origin) | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120461 (CHEMBL3617983) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120456 (CHEMBL3617978) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120484 (CHEMBL3617988) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120466 (CHEMBL3617986) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120459 (CHEMBL3617981) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120463 (CHEMBL3617984) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120464 (CHEMBL3617985) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120487 (CHEMBL3617991) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120457 (CHEMBL3617979) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50176808 (5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP3A4 (unknown origin) incubated for 45 mins using NADPH by fluorescence assay | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120485 (CHEMBL3617989) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120458 (CHEMBL3617980) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120486 (CHEMBL3617990) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50176808 (5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benz...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120460 (CHEMBL3617982) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120476 (CHEMBL3617987) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50120488 (CHEMBL3617992) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in ATRA-induced human HL60 cell microsomes incubated for 30 mins in dark condition with NADPH and ATRA by HPLC method | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50120461 (CHEMBL3617983) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP3A4 (unknown origin) incubated for 45 mins using NADPH by fluorescence assay | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50176808 (5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP2D6 (unknown origin) incubated for 45 mins using NADPH and ATRA by HPLC assay | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50120466 (CHEMBL3617986) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP3A4 (unknown origin) incubated for 45 mins using NADPH by fluorescence assay | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50120461 (CHEMBL3617983) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP2D6 (unknown origin) incubated for 45 mins using NADPH and ATRA by HPLC assay | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50120466 (CHEMBL3617986) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shenyang Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CYP2D6 (unknown origin) incubated for 45 mins using NADPH and ATRA by HPLC assay | Bioorg Med Chem 23: 6763-73 (2015) Article DOI: 10.1016/j.bmc.2015.08.019 BindingDB Entry DOI: 10.7270/Q2668G0C | |||||||||||
More data for this Ligand-Target Pair |