BindingDB PrimarySearch

Found 21 hits Enz. Inhib. hit(s) with all data for entry = 50029929
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50083595 (3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289417 ((R)-2-Amino-3-(3-m-tolyloxy-phenylamino)-propane-1...) Show SMILES Cc1cccc(Oc2cccc(NC[C@@H](N)CS)c2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289422 (CHEMBL26314 \| {3-[4-((R)-2-Amino-3-mercapto-propyl...) Show SMILES N[C@@H](CS)CNc1ccc(Oc2cccc(CO)c2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289429 (3-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289427 ((R)-2-Amino-3-(4-phenoxy-phenylamino)-propane-1-th...) Show SMILES N[C@@H](CS)CNc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289420 ((R)-2-Amino-3-(4-m-tolyloxy-phenylamino)-propane-1...) Show SMILES Cc1cccc(Oc2ccc(NC[C@@H](N)CS)cc2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	615	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289425 (3-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289431 ((R)-2-Amino-3-(3-phenoxy-phenylamino)-propane-1-th...) Show SMILES N[C@@H](CS)CNc1cccc(Oc2ccccc2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289425 (3-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289423 (4-[4-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289428 (4-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289427 ((R)-2-Amino-3-(4-phenoxy-phenylamino)-propane-1-th...) Show SMILES N[C@@H](CS)CNc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50083595 (3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289426 (3-[3-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289421 (3-[4-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289424 (4-[4-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289416 (3-[4-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289419 (3-[3-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289418 (4-[3-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289432 (4-[3-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50289430 (4-[4-((R)-2-Amino-3-mercapto-propionylamino)-pheno...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 ...				Bioorg Med Chem Lett 7: 1345-1348 (1997) Article DOI: 10.1016/S0960-894X(97)00225-4 BindingDB Entry DOI: 10.7270/Q28W3D96
TBA Curated by ChEMBL					More data for this Ligand-Target Pair