Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50030781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50301291 (4-Benzyl-2-methyl-7,8,9,10-tetrahyd ro-6H-1,3,3a,5...) Show SMILES Cc1nc2c3CCNCCc3nc(Cc3ccccc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-12-19-17-14-7-9-18-10-8-15(14)20-16(22(17)21-12)11-13-5-3-2-4-6-13/h2-6,18H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of 5HT3 receptor				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50301291 (4-Benzyl-2-methyl-7,8,9,10-tetrahyd ro-6H-1,3,3a,5...) Show SMILES Cc1nc2c3CCNCCc3nc(Cc3ccccc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-12-19-17-14-7-9-18-10-8-15(14)20-16(22(17)21-12)11-13-5-3-2-4-6-13/h2-6,18H,7-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of beta2 adrenergic receptor				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50301291 (4-Benzyl-2-methyl-7,8,9,10-tetrahyd ro-6H-1,3,3a,5...) Show SMILES Cc1nc2c3CCNCCc3nc(Cc3ccccc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-12-19-17-14-7-9-18-10-8-15(14)20-16(22(17)21-12)11-13-5-3-2-4-6-13/h2-6,18H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of muscarinic receptor 3				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50301291 (4-Benzyl-2-methyl-7,8,9,10-tetrahyd ro-6H-1,3,3a,5...) Show SMILES Cc1nc2c3CCNCCc3nc(Cc3ccccc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-12-19-17-14-7-9-18-10-8-15(14)20-16(22(17)21-12)11-13-5-3-2-4-6-13/h2-6,18H,7-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of dofrtilide from human ERG channel				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301289 (1-benzyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1ncc2CCNCCc12 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)11-17-14-7-9-15-8-6-13(14)10-16-17/h1-5,10,15H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301290 (3-(benzyloxy)-1,4,5,6,7,8-hexahydropyrazolo[4,3-d]...) Show SMILES C(Oc1[nH]nc2CCNCCc12)c1ccccc1 Show InChI InChI=1S/C14H17N3O/c1-2-4-11(5-3-1)10-18-14-12-6-8-15-9-7-13(12)16-17-14/h1-5,15H,6-10H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	353	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Canis familiaris)	BDBM50301291 (4-Benzyl-2-methyl-7,8,9,10-tetrahyd ro-6H-1,3,3a,5...) Show SMILES Cc1nc2c3CCNCCc3nc(Cc3ccccc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-12-19-17-14-7-9-18-10-8-15(14)20-16(22(17)21-12)11-13-5-3-2-4-6-13/h2-6,18H,7-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at 5-HT2A receptor in dog bladder strip				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Canis familiaris)	BDBM50301292 (4-Benzyl-3-methyl-7,8,9,10-tetrahyd ro-6H-1,2,3a,5...) Show SMILES Cc1nnc2c3CCNCCc3nc(Cc3ccccc3)n12 Show InChI InChI=1S/C17H19N5/c1-12-20-21-17-14-7-9-18-10-8-15(14)19-16(22(12)17)11-13-5-3-2-4-6-13/h2-6,18H,7-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at 5-HT2A receptor in dog bladder strip				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301285 (1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1[nH]n(Cc2ccccc2)c2CCNCCc12 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)17(16-14)10-11-4-2-1-3-5-11/h1-5,15H,6-10H2,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50001915 (1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...) Show SMILES Clc1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301293 (2-methyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES Cn1nc2CCNCCc2cc1=O Show InChI InChI=1S/C9H13N3O/c1-12-9(13)6-7-2-4-10-5-3-8(7)11-12/h6,10H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	338	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301294 (2-phenyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1-c1ccccc1 Show InChI InChI=1S/C14H15N3O/c18-14-10-11-6-8-15-9-7-13(11)16-17(14)12-4-2-1-3-5-12/h1-5,10,15H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301295 (2-(2-phenoxyethyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES O=c1cc2CCNCCc2nn1CCOc1ccccc1 Show InChI InChI=1S/C16H19N3O2/c20-16-12-13-6-8-17-9-7-15(13)18-19(16)10-11-21-14-4-2-1-3-5-14/h1-5,12,17H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301296 (2-isopentyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d...) Show SMILES CC(C)CCn1nc2CCNCCc2cc1=O Show InChI InChI=1S/C13H21N3O/c1-10(2)5-8-16-13(17)9-11-3-6-14-7-4-12(11)15-16/h9-10,14H,3-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301298 (2-(2-chlorobenzyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES Clc1ccccc1Cn1nc2CCNCCc2cc1=O Show InChI InChI=1S/C15H16ClN3O/c16-13-4-2-1-3-12(13)10-19-15(20)9-11-5-7-17-8-6-14(11)18-19/h1-4,9,17H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301299 (2-(3-chlorobenzyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES Clc1cccc(Cn2nc3CCNCCc3cc2=O)c1 Show InChI InChI=1S/C15H16ClN3O/c16-13-3-1-2-11(8-13)10-19-15(20)9-12-4-6-17-7-5-14(12)18-19/h1-3,8-9,17H,4-7,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301300 (2-(4-chlorobenzyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES Clc1ccc(Cn2nc3CCNCCc3cc2=O)cc1 Show InChI InChI=1S/C15H16ClN3O/c16-13-3-1-11(2-4-13)10-19-15(20)9-12-5-7-17-8-6-14(12)18-19/h1-4,9,17H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301301 (4-((3-oxo-3,5,6,7,8,9-hexahydro-2H-pyridazino[4,3-...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C16H16N4O/c17-10-12-1-3-13(4-2-12)11-20-16(21)9-14-5-7-18-8-6-15(14)19-20/h1-4,9,18H,5-8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.63E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301302 (2-(4-(trifluoromethyl)benzyl)-6,7,8,9-tetrahydro-2...) Show SMILES FC(F)(F)c1ccc(Cn2nc3CCNCCc3cc2=O)cc1 Show InChI InChI=1S/C16H16F3N3O/c17-16(18,19)13-3-1-11(2-4-13)10-22-15(23)9-12-5-7-20-8-6-14(12)21-22/h1-4,9,20H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301303 (2-(4-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-...) Show SMILES FC(F)(F)Oc1ccc(Cn2nc3CCNCCc3cc2=O)cc1 Show InChI InChI=1S/C16H16F3N3O2/c17-16(18,19)24-13-3-1-11(2-4-13)10-22-15(23)9-12-5-7-20-8-6-14(12)21-22/h1-4,9,20H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301304 (2-(2-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-...) Show SMILES FC(F)(F)Oc1ccccc1Cn1nc2CCNCCc2cc1=O Show InChI InChI=1S/C16H16F3N3O2/c17-16(18,19)24-14-4-2-1-3-12(14)10-22-15(23)9-11-5-7-20-8-6-13(11)21-22/h1-4,9,20H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301305 (2-(4-cyclopropylbenzyl)-6,7,8,9-tetrahydro-2H-pyri...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccc(cc1)C1CC1 Show InChI InChI=1S/C18H21N3O/c22-18-11-16-7-9-19-10-8-17(16)20-21(18)12-13-1-3-14(4-2-13)15-5-6-15/h1-4,11,15,19H,5-10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301298 (2-(2-chlorobenzyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES Clc1ccccc1Cn1nc2CCNCCc2cc1=O Show InChI InChI=1S/C15H16ClN3O/c16-13-4-2-1-3-12(13)10-19-15(20)9-11-5-7-17-8-6-14(11)18-19/h1-4,9,17H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301299 (2-(3-chlorobenzyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES Clc1cccc(Cn2nc3CCNCCc3cc2=O)c1 Show InChI InChI=1S/C15H16ClN3O/c16-13-3-1-2-11(8-13)10-19-15(20)9-12-4-6-17-7-5-14(12)18-19/h1-3,8-9,17H,4-7,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301300 (2-(4-chlorobenzyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES Clc1ccc(Cn2nc3CCNCCc3cc2=O)cc1 Show InChI InChI=1S/C15H16ClN3O/c16-13-3-1-11(2-4-13)10-19-15(20)9-12-5-7-17-8-6-14(12)18-19/h1-4,9,17H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	267	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301302 (2-(4-(trifluoromethyl)benzyl)-6,7,8,9-tetrahydro-2...) Show SMILES FC(F)(F)c1ccc(Cn2nc3CCNCCc3cc2=O)cc1 Show InChI InChI=1S/C16H16F3N3O/c17-16(18,19)13-3-1-11(2-4-13)10-22-15(23)9-12-5-7-20-8-6-14(12)21-22/h1-4,9,20H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	473	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301303 (2-(4-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-...) Show SMILES FC(F)(F)Oc1ccc(Cn2nc3CCNCCc3cc2=O)cc1 Show InChI InChI=1S/C16H16F3N3O2/c17-16(18,19)24-13-3-1-11(2-4-13)10-22-15(23)9-12-5-7-20-8-6-14(12)21-22/h1-4,9,20H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301304 (2-(2-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-...) Show SMILES FC(F)(F)Oc1ccccc1Cn1nc2CCNCCc2cc1=O Show InChI InChI=1S/C16H16F3N3O2/c17-16(18,19)24-14-4-2-1-3-12(14)10-22-15(23)9-11-5-7-20-8-6-13(11)21-22/h1-4,9,20H,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	142	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301305 (2-(4-cyclopropylbenzyl)-6,7,8,9-tetrahydro-2H-pyri...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccc(cc1)C1CC1 Show InChI InChI=1S/C18H21N3O/c22-18-11-16-7-9-19-10-8-17(16)20-21(18)12-13-1-3-14(4-2-13)15-5-6-15/h1-4,11,15,19H,5-10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50001915 (1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...) Show SMILES Clc1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301294 (2-phenyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1-c1ccccc1 Show InChI InChI=1S/C14H15N3O/c18-14-10-11-6-8-15-9-7-13(11)16-17(14)12-4-2-1-3-5-12/h1-5,10,15H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301295 (2-(2-phenoxyethyl)-6,7,8,9-tetrahydro-2H-pyridazin...) Show SMILES O=c1cc2CCNCCc2nn1CCOc1ccccc1 Show InChI InChI=1S/C16H19N3O2/c20-16-12-13-6-8-17-9-7-15(13)18-19(16)10-11-21-14-4-2-1-3-5-14/h1-5,12,17H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301297 (2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]az...) Show SMILES O=c1cc2CCNCCc2nn1Cc1ccccc1 Show InChI InChI=1S/C15H17N3O/c19-15-10-13-6-8-16-9-7-14(13)17-18(15)11-12-4-2-1-3-5-12/h1-5,10,16H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	358	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301286 (2-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1c2CCNCCc2[nH]n1Cc1ccccc1 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)16-17(14)10-11-4-2-1-3-5-11/h1-5,15-16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301287 (2-benzyl-1-methyl-1,2,5,6,7,8-hexahydropyrazolo[4,...) Show SMILES Cn1c2CCNCCc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C15H19N3O/c1-17-14-8-10-16-9-7-13(14)15(19)18(17)11-12-5-3-2-4-6-12/h2-6,16H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301288 (2-benzyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1cc2CCNCCc2n1 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)10-17-11-13-6-8-15-9-7-14(13)16-17/h1-5,11,15H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.98E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301289 (1-benzyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1ncc2CCNCCc12 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)11-17-14-7-9-15-8-6-13(14)10-16-17/h1-5,10,15H,6-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301288 (2-benzyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES C(c1ccccc1)n1cc2CCNCCc2n1 Show InChI InChI=1S/C14H17N3/c1-2-4-12(5-3-1)10-17-11-13-6-8-15-9-7-14(13)16-17/h1-5,11,15H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301287 (2-benzyl-1-methyl-1,2,5,6,7,8-hexahydropyrazolo[4,...) Show SMILES Cn1c2CCNCCc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C15H19N3O/c1-17-14-8-10-16-9-7-13(14)15(19)18(17)11-12-5-3-2-4-6-12/h2-6,16H,7-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301286 (2-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1c2CCNCCc2[nH]n1Cc1ccccc1 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)16-17(14)10-11-4-2-1-3-5-11/h1-5,15-16H,6-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50301290 (3-(benzyloxy)-1,4,5,6,7,8-hexahydropyrazolo[4,3-d]...) Show SMILES C(Oc1[nH]nc2CCNCCc12)c1ccccc1 Show InChI InChI=1S/C14H17N3O/c1-2-4-11(5-3-1)10-18-14-12-6-8-15-9-7-13(12)16-17-14/h1-5,15H,6-10H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	176	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50301285 (1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...) Show SMILES O=c1[nH]n(Cc2ccccc2)c2CCNCCc12 Show InChI InChI=1S/C14H17N3O/c18-14-12-6-8-15-9-7-13(12)17(16-14)10-11-4-2-1-3-5-11/h1-5,15H,6-10H2,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 4999-5003 (2009) Article DOI: 10.1016/j.bmcl.2009.07.063 BindingDB Entry DOI: 10.7270/Q29C6XHC
					More data for this Ligand-Target Pair