Compile Data Set for Download or QSAR

Found 63 hits Enz. Inhib. hit(s) with all data for entry = 50032698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES [H][C@@]12CCC(=O)[C@@]1(C)C[C@@H](OC(C)=O)C1=C2C(=O)c2occ3c2[C@]1(C)[C@@H](COC)OC3=O |r,c:15| Show InChI InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES [H][C@@]12CCC(=O)[C@@]1(C)C[C@@H](OC(C)=O)C1=C2C(=O)c2occ3c2[C@]1(C)[C@@H](COC)OC3=O |r,c:15| Show InChI InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES [H][C@@]12CCC(=O)[C@@]1(C)C[C@@H](OC(C)=O)C1=C2C(=O)c2occ3c2[C@]1(C)[C@@H](COC)OC3=O |r,c:15| Show InChI InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES [H][C@@]12CCC(=O)[C@@]1(C)C[C@@H](OC(C)=O)C1=C2C(=O)c2occ3c2[C@]1(C)[C@@H](COC)OC3=O |r,c:15| Show InChI InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333219 (6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...) Show SMILES COc1ccc(cn1)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-17-12-5-3-9(7-15-12)8-2-4-10-11(6-8)18-13(14)16-10/h2-7H,1H3,(H2,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333219 (6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...) Show SMILES COc1ccc(cn1)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-17-12-5-3-9(7-15-12)8-2-4-10-11(6-8)18-13(14)16-10/h2-7H,1H3,(H2,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333220 (5-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2cc(ccc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-7-9(1-2-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333220 (5-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2cc(ccc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-7-9(1-2-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333215 (7-morpholinoquinazolin-4(3H)-one | CHEMBL1645100) Show SMILES O=c1[nH]cnc2cc(ccc12)N1CCOCC1 Show InChI InChI=1S/C12H13N3O2/c16-12-10-2-1-9(7-11(10)13-8-14-12)15-3-5-17-6-4-15/h1-2,7-8H,3-6H2,(H,13,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333215 (7-morpholinoquinazolin-4(3H)-one | CHEMBL1645100) Show SMILES O=c1[nH]cnc2cc(ccc12)N1CCOCC1 Show InChI InChI=1S/C12H13N3O2/c16-12-10-2-1-9(7-11(10)13-8-14-12)15-3-5-17-6-4-15/h1-2,7-8H,3-6H2,(H,13,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333222 (3-(2-aminobenzo[d]thiazol-6-yl)phenol | CHEMBL1645...) Show SMILES Nc1nc2ccc(cc2s1)-c1cccc(O)c1 Show InChI InChI=1S/C13H10N2OS/c14-13-15-11-5-4-9(7-12(11)17-13)8-2-1-3-10(16)6-8/h1-7,16H,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333226 (4-(5-(thiophen-2-ylmethyl)-1,2,4-oxadiazol-3-yl)-1...) Show SMILES Nc1nonc1-c1noc(Cc2cccs2)n1 Show InChI InChI=1S/C9H7N5O2S/c10-8-7(12-16-13-8)9-11-6(15-14-9)4-5-2-1-3-17-5/h1-3H,4H2,(H2,10,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333221 (6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2ccc(cc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333221 (6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2ccc(cc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50333222 (3-(2-aminobenzo[d]thiazol-6-yl)phenol | CHEMBL1645...) Show SMILES Nc1nc2ccc(cc2s1)-c1cccc(O)c1 Show InChI InChI=1S/C13H10N2OS/c14-13-15-11-5-4-9(7-12(11)17-13)8-2-1-3-10(16)6-8/h1-7,16H,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50333221 (6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2ccc(cc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333220 (5-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2cc(ccc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-7-9(1-2-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333222 (3-(2-aminobenzo[d]thiazol-6-yl)phenol | CHEMBL1645...) Show SMILES Nc1nc2ccc(cc2s1)-c1cccc(O)c1 Show InChI InChI=1S/C13H10N2OS/c14-13-15-11-5-4-9(7-12(11)17-13)8-2-1-3-10(16)6-8/h1-7,16H,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333211 (2-(pyridin-4-yl)thiazolo[5,4-d]pyrimidin-7-amine |...) Show SMILES Nc1ncnc2sc(nc12)-c1ccncc1 Show InChI InChI=1S/C10H7N5S/c11-8-7-10(14-5-13-8)16-9(15-7)6-1-3-12-4-2-6/h1-5H,(H2,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333222 (3-(2-aminobenzo[d]thiazol-6-yl)phenol | CHEMBL1645...) Show SMILES Nc1nc2ccc(cc2s1)-c1cccc(O)c1 Show InChI InChI=1S/C13H10N2OS/c14-13-15-11-5-4-9(7-12(11)17-13)8-2-1-3-10(16)6-8/h1-7,16H,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333216 (4-(1H-pyrazolo[3,4-b]pyridin-4-yl)morpholine | CHE...) Show SMILES C1CN(CCO1)c1ccnc2[nH]ncc12 Show InChI InChI=1S/C10H12N4O/c1-2-11-10-8(7-12-13-10)9(1)14-3-5-15-6-4-14/h1-2,7H,3-6H2,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333221 (6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2ccc(cc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333226 (4-(5-(thiophen-2-ylmethyl)-1,2,4-oxadiazol-3-yl)-1...) Show SMILES Nc1nonc1-c1noc(Cc2cccs2)n1 Show InChI InChI=1S/C9H7N5O2S/c10-8-7(12-16-13-8)9-11-6(15-14-9)4-5-2-1-3-17-5/h1-3H,4H2,(H2,10,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333215 (7-morpholinoquinazolin-4(3H)-one | CHEMBL1645100) Show SMILES O=c1[nH]cnc2cc(ccc12)N1CCOCC1 Show InChI InChI=1S/C12H13N3O2/c16-12-10-2-1-9(7-11(10)13-8-14-12)15-3-5-17-6-4-15/h1-2,7-8H,3-6H2,(H,13,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333210 (5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | CHEMB...) Show SMILES c1cc2cc(cnc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C12H9N3/c1-4-13-5-2-9(1)11-7-10-3-6-14-12(10)15-8-11/h1-8H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333216 (4-(1H-pyrazolo[3,4-b]pyridin-4-yl)morpholine | CHE...) Show SMILES C1CN(CCO1)c1ccnc2[nH]ncc12 Show InChI InChI=1S/C10H12N4O/c1-2-11-10-8(7-12-13-10)9(1)14-3-5-15-6-4-14/h1-2,7H,3-6H2,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333211 (2-(pyridin-4-yl)thiazolo[5,4-d]pyrimidin-7-amine |...) Show SMILES Nc1ncnc2sc(nc12)-c1ccncc1 Show InChI InChI=1S/C10H7N5S/c11-8-7-10(14-5-13-8)16-9(15-7)6-1-3-12-4-2-6/h1-5H,(H2,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333217 (4-methyl-2-morpholinothiazole-5-carboxylic acid | ...) Show SMILES Cc1nc(sc1C(O)=O)N1CCOCC1 Show InChI InChI=1S/C9H12N2O3S/c1-6-7(8(12)13)15-9(10-6)11-2-4-14-5-3-11/h2-5H2,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333217 (4-methyl-2-morpholinothiazole-5-carboxylic acid | ...) Show SMILES Cc1nc(sc1C(O)=O)N1CCOCC1 Show InChI InChI=1S/C9H12N2O3S/c1-6-7(8(12)13)15-9(10-6)11-2-4-14-5-3-11/h2-5H2,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50024966 (6-Oxo-1,6-dihydro-[3,4']bipyridinyl-5-carbonitrile...) Show SMILES O=c1[nH]cc(cc1C#N)-c1ccncc1 Show InChI InChI=1S/C11H7N3O/c12-6-9-5-10(7-14-11(9)15)8-1-3-13-4-2-8/h1-5,7H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333211 (2-(pyridin-4-yl)thiazolo[5,4-d]pyrimidin-7-amine |...) Show SMILES Nc1ncnc2sc(nc12)-c1ccncc1 Show InChI InChI=1S/C10H7N5S/c11-8-7-10(14-5-13-8)16-9(15-7)6-1-3-12-4-2-6/h1-5H,(H2,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50024966 (6-Oxo-1,6-dihydro-[3,4']bipyridinyl-5-carbonitrile...) Show SMILES O=c1[nH]cc(cc1C#N)-c1ccncc1 Show InChI InChI=1S/C11H7N3O/c12-6-9-5-10(7-14-11(9)15)8-1-3-13-4-2-8/h1-5,7H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333217 (4-methyl-2-morpholinothiazole-5-carboxylic acid | ...) Show SMILES Cc1nc(sc1C(O)=O)N1CCOCC1 Show InChI InChI=1S/C9H12N2O3S/c1-6-7(8(12)13)15-9(10-6)11-2-4-14-5-3-11/h2-5H2,1H3,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333216 (4-(1H-pyrazolo[3,4-b]pyridin-4-yl)morpholine | CHE...) Show SMILES C1CN(CCO1)c1ccnc2[nH]ncc12 Show InChI InChI=1S/C10H12N4O/c1-2-11-10-8(7-12-13-10)9(1)14-3-5-15-6-4-14/h1-2,7H,3-6H2,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333218 (7-morpholinopyrimido[4,5-d]pyrimidin-4-amine | CHE...) Show SMILES Nc1ncnc2nc(ncc12)N1CCOCC1 Show InChI InChI=1S/C10H12N6O/c11-8-7-5-12-10(15-9(7)14-6-13-8)16-1-3-17-4-2-16/h5-6H,1-4H2,(H2,11,12,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333212 (2-(pyridin-4-yl)benzo[d]oxazol-5-ol | CHEMBL164509...) Show SMILES Oc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C12H8N2O2/c15-9-1-2-11-10(7-9)14-12(16-11)8-3-5-13-6-4-8/h1-7,15H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333224 (2-(dimethylamino)-6-morpholinopyrimidin-4(3H)-one ...) Show SMILES CN(C)c1nc(cc(=O)[nH]1)N1CCOCC1 Show InChI InChI=1S/C10H16N4O2/c1-13(2)10-11-8(7-9(15)12-10)14-3-5-16-6-4-14/h7H,3-6H2,1-2H3,(H,11,12,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333218 (7-morpholinopyrimido[4,5-d]pyrimidin-4-amine | CHE...) Show SMILES Nc1ncnc2nc(ncc12)N1CCOCC1 Show InChI InChI=1S/C10H12N6O/c11-8-7-5-12-10(15-9(7)14-6-13-8)16-1-3-17-4-2-16/h5-6H,1-4H2,(H2,11,12,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333210 (5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | CHEMB...) Show SMILES c1cc2cc(cnc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C12H9N3/c1-4-13-5-2-9(1)11-7-10-3-6-14-12(10)15-8-11/h1-8H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50333213 (5-(pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2...) Show SMILES Nc1nc2nc(ccn2n1)-c1ccncc1 Show InChI InChI=1S/C10H8N6/c11-9-14-10-13-8(3-6-16(10)15-9)7-1-4-12-5-2-7/h1-6H,(H2,11,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333218 (7-morpholinopyrimido[4,5-d]pyrimidin-4-amine | CHE...) Show SMILES Nc1ncnc2nc(ncc12)N1CCOCC1 Show InChI InChI=1S/C10H12N6O/c11-8-7-5-12-10(15-9(7)14-6-13-8)16-1-3-17-4-2-16/h5-6H,1-4H2,(H2,11,12,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50333211 (2-(pyridin-4-yl)thiazolo[5,4-d]pyrimidin-7-amine |...) Show SMILES Nc1ncnc2sc(nc12)-c1ccncc1 Show InChI InChI=1S/C10H7N5S/c11-8-7-10(14-5-13-8)16-9(15-7)6-1-3-12-4-2-6/h1-5H,(H2,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333223 (6-amino-2'-methyl-3,4'-bipyridine-5-carboxamide | ...) Show SMILES Cc1cc(ccn1)-c1cnc(N)c(c1)C(N)=O Show InChI InChI=1S/C12H12N4O/c1-7-4-8(2-3-15-7)9-5-10(12(14)17)11(13)16-6-9/h2-6H,1H3,(H2,13,16)(H2,14,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50333213 (5-(pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2...) Show SMILES Nc1nc2nc(ccn2n1)-c1ccncc1 Show InChI InChI=1S/C10H8N6/c11-9-14-10-13-8(3-6-16(10)15-9)7-1-4-12-5-2-7/h1-6H,(H2,11,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333225 (1-methyl-1H-pyrrolo[2,3-c]pyridin-5-amine | CHEMBL...) Show SMILES Cn1ccc2cc(N)ncc12 Show InChI InChI=1S/C8H9N3/c1-11-3-2-6-4-8(9)10-5-7(6)11/h2-5H,1H3,(H2,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50333210 (5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | CHEMB...) Show SMILES c1cc2cc(cnc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C12H9N3/c1-4-13-5-2-9(1)11-7-10-3-6-14-12(10)15-8-11/h1-8H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human p110alpha PI3K fragment by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50333213 (5-(pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2...) Show SMILES Nc1nc2nc(ccn2n1)-c1ccncc1 Show InChI InChI=1S/C10H8N6/c11-9-14-10-13-8(3-6-16(10)15-9)7-1-4-12-5-2-7/h1-6H,(H2,11,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50024966 (6-Oxo-1,6-dihydro-[3,4']bipyridinyl-5-carbonitrile...) Show SMILES O=c1[nH]cc(cc1C#N)-c1ccncc1 Show InChI InChI=1S/C11H7N3O/c12-6-9-5-10(7-14-11(9)15)8-1-3-13-4-2-8/h1-5,7H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50333210 (5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine | CHEMB...) Show SMILES c1cc2cc(cnc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C12H9N3/c1-4-13-5-2-9(1)11-7-10-3-6-14-12(10)15-8-11/h1-8H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50333220 (5-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...) Show SMILES Nc1nc2cc(ccc2s1)-c1ccncc1 Show InChI InChI=1S/C12H9N3S/c13-12-15-10-7-9(1-2-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D M£lndal Curated by ChEMBL					Assay Description Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assay				Bioorg Med Chem Lett 21: 829-35 (2011) Article DOI: 10.1016/j.bmcl.2010.11.087 BindingDB Entry DOI: 10.7270/Q298878P
					More data for this Ligand-Target Pair

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