Compile Data Set for Download or QSAR

Found 84 hits Enz. Inhib. hit(s) with all data for entry = 50033889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu5 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu2 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu7 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu7 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu3 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu7 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu1 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu1 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu1 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu2 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu2 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu5 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu5 receptor				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50353293 (CHEMBL1830693) Show SMILES N(c1nc(cs1)-c1cn[nH]c1)c1ccccn1 Show InChI InChI=1S/C11H9N5S/c1-2-4-12-10(3-1)16-11-15-9(7-17-11)8-5-13-14-6-8/h1-7H,(H,13,14)(H,12,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu2 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu5 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu1 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu2 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu5 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu1 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50353291 (CHEMBL1830711) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ncccn3)sc2C1 Show InChI InChI=1S/C13H12N6S/c1-3-9-8(7-16-19-9)11-10(4-1)20-13(17-11)18-12-14-5-2-6-15-12/h2,5-7H,1,3-4H2,(H,16,19)(H,14,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu2 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50353290 (CHEMBL1830707) Show SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1 Show InChI InChI=1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu5 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50353292 (CHEMBL1830698) Show SMILES C1Cc2sc(Nc3ccccn3)nc2-c2cn[nH]c12 Show InChI InChI=1S/C13H11N5S/c1-2-6-14-11(3-1)16-13-17-12-8-7-15-18-9(8)4-5-10(12)19-13/h1-3,6-7H,4-5H2,(H,15,18)(H,14,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilization				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353294 (CHEMBL1830915) Show SMILES COc1ccnc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C14H14N6OS/c1-21-11-5-6-15-13(17-11)19-14-18-12-8-7-16-20-9(8)3-2-4-10(12)22-14/h5-7H,2-4H2,1H3,(H,16,20)(H,15,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353295 (CHEMBL1830914) Show SMILES Cc1ccnc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C14H14N6S/c1-8-5-6-15-13(17-8)19-14-18-12-9-7-16-20-10(9)3-2-4-11(12)21-14/h5-7H,2-4H2,1H3,(H,16,20)(H,15,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353296 (CHEMBL1830913) Show SMILES C1CCN(C1)c1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C18H20N6S/c1-2-10-24(9-1)16-8-4-7-15(20-16)21-18-22-17-12-11-19-23-13(12)5-3-6-14(17)25-18/h4,7-8,11H,1-3,5-6,9-10H2,(H,19,23)(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353297 (CHEMBL1830912) Show SMILES CCNc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C16H18N6S/c1-2-17-13-7-4-8-14(19-13)20-16-21-15-10-9-18-22-11(10)5-3-6-12(15)23-16/h4,7-9H,2-3,5-6H2,1H3,(H,18,22)(H2,17,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353298 (CHEMBL1830911) Show SMILES CN(C)c1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C16H18N6S/c1-22(2)14-8-4-7-13(18-14)19-16-20-15-10-9-17-21-11(10)5-3-6-12(15)23-16/h4,7-9H,3,5-6H2,1-2H3,(H,17,21)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353299 (CHEMBL1830910) Show SMILES COCCOc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C17H19N5O2S/c1-23-8-9-24-15-7-3-6-14(19-15)20-17-21-16-11-10-18-22-12(11)4-2-5-13(16)25-17/h3,6-7,10H,2,4-5,8-9H2,1H3,(H,18,22)(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353300 (CHEMBL1830909) Show SMILES OCc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C15H15N5OS/c21-8-9-3-1-6-13(17-9)18-15-19-14-10-7-16-20-11(10)4-2-5-12(14)22-15/h1,3,6-7,21H,2,4-5,8H2,(H,16,20)(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353301 (CHEMBL1830908) Show SMILES COC(=O)c1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C16H15N5O2S/c1-23-15(22)11-5-3-7-13(18-11)19-16-20-14-9-8-17-21-10(9)4-2-6-12(14)24-16/h3,5,7-8H,2,4,6H2,1H3,(H,17,21)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353302 (CHEMBL1830907) Show SMILES N#Cc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C15H12N6S/c16-7-9-3-1-6-13(18-9)19-15-20-14-10-8-17-21-11(10)4-2-5-12(14)22-15/h1,3,6,8H,2,4-5H2,(H,17,21)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353303 (CHEMBL1830906) Show SMILES CCOc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C16H17N5OS/c1-2-22-14-8-4-7-13(18-14)19-16-20-15-10-9-17-21-11(10)5-3-6-12(15)23-16/h4,7-9H,2-3,5-6H2,1H3,(H,17,21)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353304 (CHEMBL1830905) Show SMILES COc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C15H15N5OS/c1-21-13-7-3-6-12(17-13)18-15-19-14-9-8-16-20-10(9)4-2-5-11(14)22-15/h3,6-8H,2,4-5H2,1H3,(H,16,20)(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353305 (CHEMBL1830904) Show SMILES Clc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C14H12ClN5S/c15-11-5-2-6-12(17-11)18-14-19-13-8-7-16-20-9(8)3-1-4-10(13)21-14/h2,5-7H,1,3-4H2,(H,16,20)(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353306 (CHEMBL1830903) Show SMILES Fc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C14H12FN5S/c15-11-5-2-6-12(17-11)18-14-19-13-8-7-16-20-9(8)3-1-4-10(13)21-14/h2,5-7H,1,3-4H2,(H,16,20)(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353307 (CHEMBL1830902) Show SMILES Fc1ccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)nc1 Show InChI InChI=1S/C14H12FN5S/c15-8-4-5-12(16-6-8)18-14-19-13-9-7-17-20-10(9)2-1-3-11(13)21-14/h4-7H,1-3H2,(H,17,20)(H,16,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353308 (CHEMBL1830901) Show SMILES Cc1cc(C)nc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)c1 Show InChI InChI=1S/C16H17N5S/c1-9-6-10(2)18-14(7-9)19-16-20-15-11-8-17-21-12(11)4-3-5-13(15)22-16/h6-8H,3-5H2,1-2H3,(H,17,21)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353309 (CHEMBL1830900) Show SMILES Cc1cccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)n1 Show InChI InChI=1S/C15H15N5S/c1-9-4-2-7-13(17-9)18-15-19-14-10-8-16-20-11(10)5-3-6-12(14)21-15/h2,4,7-8H,3,5-6H2,1H3,(H,16,20)(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50353310 (CHEMBL1830899) Show SMILES Cc1ccc(Nc2nc-3c(CCCc4[nH]ncc-34)s2)nc1 Show InChI InChI=1S/C15H15N5S/c1-9-5-6-13(16-7-9)18-15-19-14-10-8-17-20-11(10)3-2-4-12(14)21-15/h5-8H,2-4H2,1H3,(H,17,20)(H,16,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...				J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5
					More data for this Ligand-Target Pair

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