Compile Data Set for Download or QSAR

Found 86 hits Enz. Inhib. hit(s) with all data for entry = 50000128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001786 (1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Compound was tested for the displacement of [3H]ketanserin from serotonin 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001797 (1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...) Show SMILES Cc1c(C2CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-9,19H,10-17H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001778 ((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 Show InChI InChI=1S/C24H27FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-8,17-18H,9-16H2,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001790 (1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C24H26F2N4O/c25-18-1-4-20(5-2-18)30-16-22(21-6-3-19(26)15-23(21)30)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001796 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES Cc1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 Show InChI InChI=1S/C25H29FN4O/c1-18-2-7-22-23(17-30(24(22)16-18)21-5-3-20(26)4-6-21)19-8-11-28(12-9-19)14-15-29-13-10-27-25(29)31/h2-7,16-17,19H,8-15H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001776 (1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...) Show SMILES Cc1c(C2=CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 |t:3| Show InChI InChI=1S/C25H27FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-10H,11-17H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001784 (3-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H28ClFN4O/c1-28(2)24(31)27-11-14-29-12-9-17(10-13-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001789 (1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(F)ccc23)C1=O Show InChI InChI=1S/C27H32F2N4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-3-21(28)4-7-23)26-17-22(29)5-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001772 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-21-22(16-30(23(21)15-18)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001782 ((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O Show InChI InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-4-22(29)5-7-23)26-17-21(28)3-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001794 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(C)ccc23)C1=O Show InChI InChI=1S/C28H35FN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-22(11-13-30)26-19-33(24-7-5-23(29)6-8-24)27-18-21(3)4-9-25(26)27/h4-9,18-20,22H,10-17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001791 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CNC(=O)N(C)CCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H28ClFN4O/c1-27-24(31)28(2)13-14-29-11-9-17(10-12-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001771 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-trifluoromethyl-1H-...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-2-4-20(5-3-19)33-16-22(21-6-1-18(15-23(21)33)25(27,28)29)17-7-10-31(11-8-17)13-14-32-12-9-30-24(32)34/h1-6,15-17H,7-14H2,(H,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001783 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CC(C)NC(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C26H33FN4O/c1-18(2)29-26(32)28-12-15-30-13-10-20(11-14-30)24-17-31(22-7-5-21(27)6-8-22)25-16-19(3)4-9-23(24)25/h4-9,16-18,20H,10-15H2,1-3H3,(H2,28,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001792 (1-Isopropyl-3-{2-[4-(6-methyl-1-phenyl-1H-indol-3-...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3)c3cc(C)ccc23)C1=O Show InChI InChI=1S/C28H36N4O/c1-21(2)31-18-17-30(28(31)33)16-15-29-13-11-23(12-14-29)26-20-32(24-7-5-4-6-8-24)27-19-22(3)9-10-25(26)27/h4-10,19-21,23H,11-18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001785 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CC(C)NC(=O)N(C)CCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H32ClFN4O/c1-18(2)29-26(33)30(3)14-15-31-12-10-19(11-13-31)24-17-32(22-7-5-21(28)6-8-22)25-16-20(27)4-9-23(24)25/h4-9,16-19H,10-15H2,1-3H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001790 (1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C24H26F2N4O/c25-18-1-4-20(5-2-18)30-16-22(21-6-3-19(26)15-23(21)30)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001781 (1-(2-{4-[1-(2-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3F)c3cc(C)ccc23)C1=O Show InChI InChI=1S/C28H35FN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-22(11-13-30)24-19-33(26-7-5-4-6-25(26)29)27-18-21(3)8-9-23(24)27/h4-9,18-20,22H,10-17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001787 (3-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C25H31FN4O/c1-18-4-9-22-23(17-30(24(22)16-18)21-7-5-20(26)6-8-21)19-10-13-29(14-11-19)15-12-27-25(31)28(2)3/h4-9,16-17,19H,10-15H2,1-3H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001799 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-trifluoromethyl-1H-...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(ccc23)C(F)(F)F)C1=O Show InChI InChI=1S/C28H32F4N4O/c1-19(2)35-16-15-34(27(35)37)14-13-33-11-9-20(10-12-33)25-18-36(23-6-4-22(29)5-7-23)26-17-21(28(30,31)32)3-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001778 ((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 Show InChI InChI=1S/C24H27FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-8,17-18H,9-16H2,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001786 (1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001790 (1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(F)cc12 Show InChI InChI=1S/C24H26F2N4O/c25-18-1-4-20(5-2-18)30-16-22(21-6-3-19(26)15-23(21)30)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001795 (1-(2-{4-[6-Chloro-1-(2-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3F)c3cc(Cl)ccc23)C1=O Show InChI InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)23-18-33(25-6-4-3-5-24(25)29)26-17-21(28)7-8-22(23)26/h3-8,17-20H,9-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001786 (1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001798 (1-{2-[4-(6-Chloro-1-phenyl-1H-indol-3-yl)-piperidi...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3)c3cc(Cl)ccc23)C1=O Show InChI InChI=1S/C27H33ClN4O/c1-20(2)31-17-16-30(27(31)33)15-14-29-12-10-21(11-13-29)25-19-32(23-6-4-3-5-7-23)26-18-22(28)8-9-24(25)26/h3-9,18-21H,10-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001780 (1-(2-{4-[1-(4-Chloro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(Cl)cc3)c3cc(C)ccc23)C1=O Show InChI InChI=1S/C28H35ClN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-22(11-13-30)26-19-33(24-7-5-23(29)6-8-24)27-18-21(3)4-9-25(26)27/h4-9,18-20,22H,10-17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001772 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-21-22(16-30(23(21)15-18)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001788 (1-(2-{4-[1-(3-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3cccc(F)c3)c3cc(C)ccc23)C1=O Show InChI InChI=1S/C28H35FN4O/c1-20(2)32-16-15-31(28(32)34)14-13-30-11-9-22(10-12-30)26-19-33(24-6-4-5-23(29)18-24)27-17-21(3)7-8-25(26)27/h4-8,17-20,22H,9-16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Compound was tested for the displacement of [3H]-spiperone from dopamine receptor D2 from rat striatal membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001789 (1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(F)ccc23)C1=O Show InChI InChI=1S/C27H32F2N4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-3-21(28)4-7-23)26-17-22(29)5-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001791 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CNC(=O)N(C)CCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H28ClFN4O/c1-27-24(31)28(2)13-14-29-11-9-17(10-12-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001779 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-isopropyl-1H-indol-...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(ccc23)C(C)C)C1=O Show InChI InChI=1S/C30H39FN4O/c1-21(2)24-5-10-27-28(20-35(29(27)19-24)26-8-6-25(31)7-9-26)23-11-13-32(14-12-23)15-16-33-17-18-34(22(3)4)30(33)36/h5-10,19-23H,11-18H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001778 ((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 Show InChI InChI=1S/C24H27FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-8,17-18H,9-16H2,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001773 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-isopropyl-1H-indol-...) Show SMILES CC(C)c1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 Show InChI InChI=1S/C27H33FN4O/c1-19(2)21-3-8-24-25(18-32(26(24)17-21)23-6-4-22(28)5-7-23)20-9-12-30(13-10-20)15-16-31-14-11-29-27(31)33/h3-8,17-20H,9-16H2,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001787 (3-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C25H31FN4O/c1-18-4-9-22-23(17-30(24(22)16-18)21-7-5-20(26)6-8-21)19-10-13-29(14-11-19)15-12-27-25(31)28(2)3/h4-9,16-17,19H,10-15H2,1-3H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001776 (1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...) Show SMILES Cc1c(C2=CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 |t:3| Show InChI InChI=1S/C25H27FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-10H,11-17H2,1H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001796 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES Cc1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 Show InChI InChI=1S/C25H29FN4O/c1-18-2-7-22-23(17-30(24(22)16-18)21-5-3-20(26)4-6-21)19-8-11-28(12-9-19)14-15-29-13-10-27-25(29)31/h2-7,16-17,19H,8-15H2,1H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001785 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CC(C)NC(=O)N(C)CCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H32ClFN4O/c1-18(2)29-26(33)30(3)14-15-31-12-10-19(11-13-31)24-17-32(22-7-5-21(28)6-8-22)25-16-20(27)4-9-23(24)25/h4-9,16-19H,10-15H2,1-3H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001784 (3-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H28ClFN4O/c1-28(2)24(31)27-11-14-29-12-9-17(10-13-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001793 (1-Isopropyl-3-{2-[4-(6-methyl-1H-indol-3-yl)-piper...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2c[nH]c3cc(C)ccc23)C1=O Show InChI InChI=1S/C22H32N4O/c1-16(2)26-13-12-25(22(26)27)11-10-24-8-6-18(7-9-24)20-15-23-21-14-17(3)4-5-19(20)21/h4-5,14-16,18,23H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001789 (1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(F)ccc23)C1=O Show InChI InChI=1S/C27H32F2N4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-3-21(28)4-7-23)26-17-22(29)5-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001784 (3-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C24H28ClFN4O/c1-28(2)24(31)27-11-14-29-12-9-17(10-13-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001771 (1-(2-{4-[1-(4-Fluoro-phenyl)-6-trifluoromethyl-1H-...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-2-4-20(5-3-19)33-16-22(21-6-1-18(15-23(21)33)25(27,28)29)17-7-10-31(11-8-17)13-14-32-12-9-30-24(32)34/h1-6,15-17H,7-14H2,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001774 (1-{2-[4-(6-Chloro-1H-indol-3-yl)-piperidin-1-yl]-e...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2c[nH]c3cc(Cl)ccc23)C1=O Show InChI InChI=1S/C21H29ClN4O/c1-15(2)26-12-11-25(21(26)27)10-9-24-7-5-16(6-8-24)19-14-23-20-13-17(22)3-4-18(19)20/h3-4,13-16,23H,5-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001787 (3-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...) Show SMILES CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C25H31FN4O/c1-18-4-9-22-23(17-30(24(22)16-18)21-7-5-20(26)6-8-21)19-10-13-29(14-11-19)15-12-27-25(31)28(2)3/h4-9,16-17,19H,10-15H2,1-3H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001798 (1-{2-[4-(6-Chloro-1-phenyl-1H-indol-3-yl)-piperidi...) Show SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3)c3cc(Cl)ccc23)C1=O Show InChI InChI=1S/C27H33ClN4O/c1-20(2)31-17-16-30(27(31)33)15-14-29-12-10-21(11-13-29)25-19-32(23-6-4-3-5-7-23)26-18-22(28)8-9-24(25)26/h3-9,18-21H,10-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Compound was tested for the displacement of [3H]-prazosin from alpha-1 adrenergic receptor of rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001772 (1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 Show InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-21-22(16-30(23(21)15-18)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes				J Med Chem 35: 4813-22 (1993) BindingDB Entry DOI: 10.7270/Q2G73CNK
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 86 total )  |  Next  |  Last  >>

Jump to: