Compile Data Set for Download or QSAR

Found 103 hits Enz. Inhib. hit(s) with all data for entry = 50036374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029246 (1-[5-(4-Benzofuran-7-yl-piperazin-1-ylmethyl)-thio...) Show SMILES O=C1CCCCN1Cc1ccc(CN2CCN(CC2)c2cccc3ccoc23)s1 Show InChI InChI=1S/C23H27N3O2S/c27-22-6-1-2-10-26(22)17-20-8-7-19(29-20)16-24-11-13-25(14-12-24)21-5-3-4-18-9-15-28-23(18)21/h3-5,7-9,15H,1-2,6,10-14,16-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029262 (Pentanoic acid {5-[4-(2-isopropoxy-phenyl)-piperaz...) Show SMILES CCCCC(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)n1C Show InChI InChI=1S/C26H40N4O2/c1-6-7-12-26(31)27(4)19-22-13-14-23(28(22)5)20-29-15-17-30(18-16-29)24-10-8-9-11-25(24)32-21(2)3/h8-11,13-14,21H,6-7,12,15-20H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029268 (Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCCC2)CC1 Show InChI InChI=1S/C25H35N3O2S/c1-20(2)30-24-10-6-5-9-23(24)27-15-13-26(14-16-27)18-22-17-21(19-31-22)25(29)28-11-7-3-4-8-12-28/h5-6,9-10,17,19-20H,3-4,7-8,11-16,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029280 (CHEMBL544371 | [5-(4-Benzofuran-7-yl-piperazin-1-y...) Show SMILES O=C(N1CCCCC1)c1ccc(CN2CCN(CC2)c2cccc3ccoc23)s1 Show InChI InChI=1S/C23H27N3O2S/c27-23(26-10-2-1-3-11-26)21-8-7-19(29-21)17-24-12-14-25(15-13-24)20-6-4-5-18-9-16-28-22(18)20/h4-9,16H,1-3,10-15,17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029277 (N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)C(=O)C(C)C)n2C)CC1 Show InChI InChI=1S/C25H38N4O2/c1-19(2)25(30)26(5)17-21-11-12-22(27(21)6)18-28-13-15-29(16-14-28)23-9-7-8-10-24(23)31-20(3)4/h7-12,19-20H,13-18H2,1-6H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001869 (1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029253 (1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethy...) Show SMILES COc1ccccc1N1CCN(CCc2ccc(CN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C24H34N4O2/c1-25-20(10-11-21(25)19-28-13-6-5-9-24(28)29)12-14-26-15-17-27(18-16-26)22-7-3-4-8-23(22)30-2/h3-4,7-8,10-11H,5-6,9,12-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029278 (1-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-e...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCc2ccc(CN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C26H38N4O2/c1-21(2)32-25-9-5-4-8-24(25)29-18-16-28(17-19-29)15-13-22-11-12-23(27(22)3)20-30-14-7-6-10-26(30)31/h4-5,8-9,11-12,21H,6-7,10,13-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029257 ((3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)p...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029270 (2-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-f...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN3C(=O)c4ccccc4C3=O)o2)CC1 Show InChI InChI=1S/C25H25N3O4/c1-31-23-9-5-4-8-22(23)27-14-12-26(13-15-27)16-18-10-11-19(32-18)17-28-24(29)20-6-2-3-7-21(20)25(28)30/h2-11H,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029267 (N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(=O)C(C)C)n2C)CC1 Show InChI InChI=1S/C27H42N4O2/c1-20(2)27(32)31(21(3)4)19-24-13-12-23(28(24)7)18-29-14-16-30(17-15-29)25-10-8-9-11-26(25)33-22(5)6/h8-13,20-22H,14-19H2,1-7H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029257 ((3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)p...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029245 (1-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-e...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1 Show InChI InChI=1S/C27H38N4O3/c1-21(2)34-25-10-6-5-9-23(25)30-19-17-29(18-20-30)16-13-22-11-12-24(28(22)3)26(32)27(33)31-14-7-4-8-15-31/h5-6,9-12,21H,4,7-8,13-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029249 (CHEMBL542483 | {5-[4-(2-Isopropoxy-phenyl)-piperaz...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C24H33N3O2S/c1-19(2)29-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-21-16-20(18-30-21)24(28)27-10-6-3-7-11-27/h4-5,8-9,16,18-19H,3,6-7,10-15,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029283 (1-(2-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmet...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CCN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C26H38N4O2/c1-21(2)32-25-9-5-4-8-24(25)29-18-16-28(17-19-29)20-23-12-11-22(27(23)3)13-15-30-14-7-6-10-26(30)31/h4-5,8-9,11-12,21H,6-7,10,13-20H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029275 (1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)s2)CC1 Show InChI InChI=1S/C24H33N3O2S/c1-19(2)29-23-8-4-3-7-22(23)26-15-13-25(14-16-26)17-20-10-11-21(30-20)18-27-12-6-5-9-24(27)28/h3-4,7-8,10-11,19H,5-6,9,12-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029260 (Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(s2)C(=O)N2CCCCCC2)CC1 Show InChI InChI=1S/C25H35N3O2S/c1-20(2)30-23-10-6-5-9-22(23)27-17-15-26(16-18-27)19-21-11-12-24(31-21)25(29)28-13-7-3-4-8-14-28/h5-6,9-12,20H,3-4,7-8,13-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029250 ({5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(s2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C24H33N3O2S/c1-19(2)29-22-9-5-4-8-21(22)26-16-14-25(15-17-26)18-20-10-11-23(30-20)24(28)27-12-6-3-7-13-27/h4-5,8-11,19H,3,6-7,12-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001869 (1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029247 (Pentanoic acid {5-[4-(2-methoxy-phenyl)-piperazin-...) Show SMILES CCCCC(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC)n1C Show InChI InChI=1S/C24H36N4O2/c1-5-6-11-24(29)25(2)18-20-12-13-21(26(20)3)19-27-14-16-28(17-15-27)22-9-7-8-10-23(22)30-4/h7-10,12-13H,5-6,11,14-19H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029287 (N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)S(C)(=O)=O)n2C)CC1 Show InChI InChI=1S/C22H34N4O3S/c1-18(2)29-22-9-7-6-8-21(22)26-14-12-25(13-15-26)17-20-11-10-19(24(20)4)16-23(3)30(5,27)28/h6-11,18H,12-17H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029272 (Cyclohexanecarboxylic acid {5-[4-(2-isopropoxy-phe...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(=O)C3CCCCC3)n2C)CC1 Show InChI InChI=1S/C30H46N4O2/c1-23(2)34(30(35)25-11-7-6-8-12-25)22-27-16-15-26(31(27)5)21-32-17-19-33(20-18-32)28-13-9-10-14-29(28)36-24(3)4/h9-10,13-16,23-25H,6-8,11-12,17-22H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029273 (Propane-2-sulfonic acid {5-[4-(2-isopropoxy-phenyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)S(=O)(=O)C(C)C)n2C)CC1 Show InChI InChI=1S/C24H38N4O3S/c1-19(2)31-24-10-8-7-9-23(24)28-15-13-27(14-16-28)18-22-12-11-21(26(22)6)17-25(5)32(29,30)20(3)4/h7-12,19-20H,13-18H2,1-6H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029286 (Butane-1-sulfonic acid {5-[4-(2-methoxy-phenyl)-pi...) Show SMILES CCCCS(=O)(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC)n1C Show InChI InChI=1S/C23H36N4O3S/c1-5-6-17-31(28,29)24(2)18-20-11-12-21(25(20)3)19-26-13-15-27(16-14-26)22-9-7-8-10-23(22)30-4/h7-12H,5-6,13-19H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029258 (3.303211-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCOCC3)n2C)CC1 Show InChI InChI=1S/C26H36N4O4/c1-20(2)34-24-7-5-4-6-22(24)29-14-12-28(13-15-29)11-10-21-8-9-23(27(21)3)25(31)26(32)30-16-18-33-19-17-30/h4-9,20H,10-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029251 (CHEMBL543905 | {5-[4-(2-Isopropoxy-phenyl)-piperaz...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(C(=O)N3CCCCC3)n2C)CC1 Show InChI InChI=1S/C25H36N4O2/c1-20(2)31-24-10-6-5-9-22(24)28-17-15-27(16-18-28)19-21-11-12-23(26(21)3)25(30)29-13-7-4-8-14-29/h5-6,9-12,20H,4,7-8,13-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029259 (CHEMBL133550 | N-{5-[4-(2-Methoxy-phenyl)-piperazi...) Show SMILES CCCN(Cc1ccc(CN2CCN(CC2)c2ccccc2OC)n1C)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C27H36N4O3S/c1-4-16-31(35(32,33)25-10-6-5-7-11-25)22-24-15-14-23(28(24)2)21-29-17-19-30(20-18-29)26-12-8-9-13-27(26)34-3/h5-15H,4,16-22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029292 (CHEMBL435198 | N-Isopropyl-N-{5-[4-(2-methoxy-phen...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)S(C)(=O)=O)n2C)CC1 Show InChI InChI=1S/C22H34N4O3S/c1-18(2)26(30(5,27)28)17-20-11-10-19(23(20)3)16-24-12-14-25(15-13-24)21-8-6-7-9-22(21)29-4/h6-11,18H,12-17H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029291 (1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(CC2CC(CN3CCCCC3=O)=NO2)CC1 |c:27| Show InChI InChI=1S/C23H34N4O3/c1-18(2)29-22-8-4-3-7-21(22)26-13-11-25(12-14-26)17-20-15-19(24-30-20)16-27-10-6-5-9-23(27)28/h3-4,7-8,18,20H,5-6,9-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029282 (Cyclohexanecarboxylic acid isopropyl-{5-[4-(2-meth...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(=O)C3CCCCC3)n2C)CC1 Show InChI InChI=1S/C28H42N4O2/c1-22(2)32(28(33)23-10-6-5-7-11-23)21-25-15-14-24(29(25)3)20-30-16-18-31(19-17-30)26-12-8-9-13-27(26)34-4/h8-9,12-15,22-23H,5-7,10-11,16-21H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029289 (N-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(C)S(C)(=O)=O)n2C)CC1 Show InChI InChI=1S/C20H30N4O3S/c1-21(28(4,25)26)15-17-9-10-18(22(17)2)16-23-11-13-24(14-12-23)19-7-5-6-8-20(19)27-3/h5-10H,11-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029255 (1-Azepan-1-yl-2-(5-{2-[4-(2-isopropoxy-phenyl)-pip...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCCC3)n2C)CC1 Show InChI InChI=1S/C28H40N4O3/c1-22(2)35-26-11-7-6-10-24(26)31-20-18-30(19-21-31)17-14-23-12-13-25(29(23)3)27(33)28(34)32-15-8-4-5-9-16-32/h6-7,10-13,22H,4-5,8-9,14-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029271 (N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)C(C)=O)n2C)CC1 Show InChI InChI=1S/C23H34N4O2/c1-18(2)29-23-9-7-6-8-22(23)27-14-12-26(13-15-27)17-21-11-10-20(25(21)5)16-24(4)19(3)28/h6-11,18H,12-17H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029263 (N-Isopropyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(C)=O)n2C)CC1 Show InChI InChI=1S/C23H34N4O2/c1-18(2)27(19(3)28)17-21-11-10-20(24(21)4)16-25-12-14-26(15-13-25)22-8-6-7-9-23(22)29-5/h6-11,18H,12-17H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029254 (Butane-1-sulfonic acid {5-[4-(2-isopropoxy-phenyl)...) Show SMILES CCCCS(=O)(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)n1C Show InChI InChI=1S/C25H40N4O3S/c1-6-7-18-33(30,31)26(4)19-22-12-13-23(27(22)5)20-28-14-16-29(17-15-28)24-10-8-9-11-25(24)32-21(2)3/h8-13,21H,6-7,14-20H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029243 (1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)o2)CC1 Show InChI InChI=1S/C24H33N3O3/c1-19(2)29-23-8-4-3-7-22(23)26-15-13-25(14-16-26)17-20-10-11-21(30-20)18-27-12-6-5-9-24(27)28/h3-4,7-8,10-11,19H,5-6,9,12-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029249 (CHEMBL542483 | {5-[4-(2-Isopropoxy-phenyl)-piperaz...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCC2)CC1 Show InChI InChI=1S/C24H33N3O2S/c1-19(2)29-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-21-16-20(18-30-21)24(28)27-10-6-3-7-11-27/h4-5,8-9,16,18-19H,3,6-7,10-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029256 (1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethy...) Show SMILES COc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1 Show InChI InChI=1S/C25H34N4O3/c1-26-20(10-11-22(26)24(30)25(31)29-13-6-3-7-14-29)12-15-27-16-18-28(19-17-27)21-8-4-5-9-23(21)32-2/h4-5,8-11H,3,6-7,12-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029278 (1-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-e...) Show SMILES CC(C)Oc1ccccc1N1CCN(CCc2ccc(CN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C26H38N4O2/c1-21(2)32-25-9-5-4-8-24(25)29-18-16-28(17-19-29)15-13-22-11-12-23(27(22)3)20-30-14-7-6-10-26(30)31/h4-5,8-9,11-12,21H,6-7,10,13-20H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029276 (1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-f...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)o2)CC1 Show InChI InChI=1S/C23H31N3O3/c1-28-22-8-5-4-7-21(22)25-15-13-24(14-16-25)17-19-10-11-20(29-19)18-26-12-6-2-3-9-23(26)27/h4-5,7-8,10-11H,2-3,6,9,12-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029268 (Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCCC2)CC1 Show InChI InChI=1S/C25H35N3O2S/c1-20(2)30-24-10-6-5-9-23(24)27-15-13-26(14-16-27)18-22-17-21(19-31-22)25(29)28-11-7-3-4-8-12-28/h5-6,9-10,17,19-20H,3-4,7-8,11-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029285 (1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCCCC3=O)o2)CC1 Show InChI InChI=1S/C26H37N3O3/c1-21(2)31-25-10-7-6-9-24(25)28-17-15-27(16-18-28)19-22-12-13-23(32-22)20-29-14-8-4-3-5-11-26(29)30/h6-7,9-10,12-13,21H,3-5,8,11,14-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029260 (Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2ccc(s2)C(=O)N2CCCCCC2)CC1 Show InChI InChI=1S/C25H35N3O2S/c1-20(2)30-23-10-6-5-9-22(23)27-17-15-26(16-18-27)19-21-11-12-24(31-21)25(29)28-13-7-3-4-8-14-28/h5-6,9-12,20H,3-4,7-8,13-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029294 (1-(2-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CCN3CCCCC3=O)n2C)CC1 Show InChI InChI=1S/C24H34N4O2/c1-25-20(12-14-28-13-6-5-9-24(28)29)10-11-21(25)19-26-15-17-27(18-16-26)22-7-3-4-8-23(22)30-2/h3-4,7-8,10-11H,5-6,9,12-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029293 (N-Benzyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1-yl...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(Cc3ccccc3)C(C)=O)n2C)CC1 Show InChI InChI=1S/C27H34N4O2/c1-22(32)31(19-23-9-5-4-6-10-23)21-25-14-13-24(28(25)2)20-29-15-17-30(18-16-29)26-11-7-8-12-27(26)33-3/h4-14H,15-21H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	>30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029284 (N-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CNC(C)=O)n2C)CC1 Show InChI InChI=1S/C20H28N4O2/c1-16(25)21-14-17-8-9-18(22(17)2)15-23-10-12-24(13-11-23)19-6-4-5-7-20(19)26-3/h4-9H,10-15H2,1-3H3,(H,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	>30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029274 (N-Benzyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1-yl...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(Cc3ccccc3)C(=O)c3ccccc3)n2C)CC1 Show InChI InChI=1S/C32H36N4O2/c1-33-28(24-34-19-21-35(22-20-34)30-15-9-10-16-31(30)38-2)17-18-29(33)25-36(23-26-11-5-3-6-12-26)32(37)27-13-7-4-8-14-27/h3-18H,19-25H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	>30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029263 (N-Isopropyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(C)=O)n2C)CC1 Show InChI InChI=1S/C23H34N4O2/c1-18(2)27(19(3)28)17-21-11-10-20(24(21)4)16-25-12-14-26(15-13-25)22-8-6-7-9-23(22)29-5/h6-11,18H,12-17H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone				J Med Chem 38: 4198-210 (1995) BindingDB Entry DOI: 10.7270/Q2GX4C61
					More data for this Ligand-Target Pair

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