BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50039031
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM8466 ((2R)-N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50096645 (3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...) Show SMILES ONC(=O)CCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Stromelysin-1 (Homo sapiens (Human))	BDBM50305115 (5-(4'-cyanobiphenyl-4-yloxy)-N-hydroxypentanamide ...) Show SMILES ONC(=O)CCCCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetry				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetry				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM8466 ((2R)-N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetry				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50096645 (3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...) Show SMILES ONC(=O)CCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetry				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Stromelysin-1 (Homo sapiens (Human))	BDBM50305115 (5-(4'-cyanobiphenyl-4-yloxy)-N-hydroxypentanamide ...) Show SMILES ONC(=O)CCCCOc1ccc(cc1)-c1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a
Duke University Curated by ChEMBL					Assay Description Binding affinity to stromelysin-1 catalytic domain				Bioorg Med Chem Lett 20: 280-2 (2010) Article DOI: 10.1016/j.bmcl.2009.10.114 BindingDB Entry DOI: 10.7270/Q20V8DQN
Duke University Curated by ChEMBL					More data for this Ligand-Target Pair