Compile Data Set for Download or QSAR

Found 77 hits Enz. Inhib. hit(s) with all data for entry = 50040448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394369 (CHEMBL2159781) Show SMILES O=C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-22-14-8-7-13-21(22)25-26-29)28-17-15-27(16-18-28)23(19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-14,23H,15-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Irreversible inhibition of human MAGL using p-nitrophenylpropionate as substrate				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394369 (CHEMBL2159781) Show SMILES O=C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-22-14-8-7-13-21(22)25-26-29)28-17-15-27(16-18-28)23(19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-14,23H,15-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394387 (CHEMBL2159800) Show SMILES O=C(N1CCC(Cc2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C19H20N4O/c24-19(23-18-9-5-4-8-17(18)20-21-23)22-12-10-16(11-13-22)14-15-6-2-1-3-7-15/h1-9,16H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394382 (CHEMBL2159805) Show SMILES Clc1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C18H18ClN5O/c19-15-5-3-4-14(12-15)13-22-8-10-23(11-9-22)18(25)24-17-7-2-1-6-16(17)20-21-24/h1-7,12H,8-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394370 (CHEMBL2159780) Show SMILES O=C(N1CCN(Cc2cccc3ccccc23)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C22H21N5O/c28-22(27-21-11-4-3-10-20(21)23-24-27)26-14-12-25(13-15-26)16-18-8-5-7-17-6-1-2-9-19(17)18/h1-11H,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394367 (CHEMBL2159783) Show SMILES Cc1ccccc1N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C18H19N5O/c1-14-6-2-4-8-16(14)21-10-12-22(13-11-21)18(24)23-17-9-5-3-7-15(17)19-20-23/h2-9H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394387 (CHEMBL2159800) Show SMILES O=C(N1CCC(Cc2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C19H20N4O/c24-19(23-18-9-5-4-8-17(18)20-21-23)22-12-10-16(11-13-22)14-15-6-2-1-3-7-15/h1-9,16H,10-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394394 (CHEMBL2159776) Show SMILES O=C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)n1nnc2ncccc12 Show InChI InChI=1S/C23H22N6O/c30-23(29-20-12-7-13-24-22(20)25-26-29)28-16-14-27(15-17-28)21(18-8-3-1-4-9-18)19-10-5-2-6-11-19/h1-13,21H,14-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of MAGL				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394375 (CHEMBL2159812) Show SMILES O=C(Nc1ccccc1)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C25H24N6O2/c32-24(26-21-9-2-1-3-10-21)20-8-6-7-19(17-20)18-29-13-15-30(16-14-29)25(33)31-23-12-5-4-11-22(23)27-28-31/h1-12,17H,13-16,18H2,(H,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394389 (CHEMBL2159798) Show SMILES O=C(N1CCN(Cc2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C18H19N5O/c24-18(23-17-9-5-4-8-16(17)19-20-23)22-12-10-21(11-13-22)14-15-6-2-1-3-7-15/h1-9H,10-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394381 (CHEMBL2159806) Show SMILES [O-][N+](=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C18H18N6O3/c25-18(23-17-7-2-1-6-16(17)19-20-23)22-10-8-21(9-11-22)13-14-4-3-5-15(12-14)24(26)27/h1-7,12H,8-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394373 (CHEMBL2159777) Show SMILES O=C(N1CCN(Cc2cccc(c2)-c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-23-12-5-4-11-22(23)25-26-29)28-15-13-27(14-16-28)18-19-7-6-10-21(17-19)20-8-2-1-3-9-20/h1-12,17H,13-16,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394371 (CHEMBL2159779) Show SMILES O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C22H21N5O/c28-22(27-21-8-4-3-7-20(21)23-24-27)26-13-11-25(12-14-26)16-17-9-10-18-5-1-2-6-19(18)15-17/h1-10,15H,11-14,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394382 (CHEMBL2159805) Show SMILES Clc1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C18H18ClN5O/c19-15-5-3-4-14(12-15)13-22-8-10-23(11-9-22)18(25)24-17-7-2-1-6-16(17)20-21-24/h1-7,12H,8-11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394384 (CHEMBL2159803) Show SMILES Brc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18BrN5O/c19-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18(25)24-17-4-2-1-3-16(17)20-21-24/h1-8H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM60622 (BDBM50300355 | US11753371, Compound JZL-184 | US91...) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of MAGL				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394386 (CHEMBL2159801) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18FN5O/c19-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18(25)24-17-4-2-1-3-16(17)20-21-24/h1-8H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394385 (CHEMBL2159802) Show SMILES Clc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18ClN5O/c19-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18(25)24-17-4-2-1-3-16(17)20-21-24/h1-8H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394390 (CHEMBL2159797) Show SMILES O=C(N1CCN(CC1)c1ccccc1)n1nnc2ccccc12 Show InChI InChI=1S/C17H17N5O/c23-17(22-16-9-5-4-8-15(16)18-19-22)21-12-10-20(11-13-21)14-6-2-1-3-7-14/h1-9H,10-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394371 (CHEMBL2159779) Show SMILES O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C22H21N5O/c28-22(27-21-8-4-3-7-20(21)23-24-27)26-13-11-25(12-14-26)16-17-9-10-18-5-1-2-6-19(18)15-17/h1-10,15H,11-14,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394383 (CHEMBL2159804) Show SMILES [O-][N+](=O)c1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18N6O3/c25-18(23-17-4-2-1-3-16(17)19-20-23)22-11-9-21(10-12-22)13-14-5-7-15(8-6-14)24(26)27/h1-8H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394376 (CHEMBL2159811) Show SMILES O=C(NC1CCCCC1)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C25H30N6O2/c32-24(26-21-9-2-1-3-10-21)20-8-6-7-19(17-20)18-29-13-15-30(16-14-29)25(33)31-23-12-5-4-11-22(23)27-28-31/h4-8,11-12,17,21H,1-3,9-10,13-16,18H2,(H,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394368 (CHEMBL2159782) Show SMILES Fc1ccccc1N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C17H16FN5O/c18-13-5-1-3-7-15(13)21-9-11-22(12-10-21)17(24)23-16-8-4-2-6-14(16)19-20-23/h1-8H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394370 (CHEMBL2159780) Show SMILES O=C(N1CCN(Cc2cccc3ccccc23)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C22H21N5O/c28-22(27-21-11-4-3-10-20(21)23-24-27)26-14-12-25(13-15-26)16-18-8-5-7-17-6-1-2-9-19(17)18/h1-11H,12-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394386 (CHEMBL2159801) Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18FN5O/c19-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18(25)24-17-4-2-1-3-16(17)20-21-24/h1-8H,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394363 (CHEMBL2159787) Show SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C18H19N5O2/c1-25-15-8-6-14(7-9-15)21-10-12-22(13-11-21)18(24)23-17-5-3-2-4-16(17)19-20-23/h2-9H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394385 (CHEMBL2159802) Show SMILES Clc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18ClN5O/c19-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18(25)24-17-4-2-1-3-16(17)20-21-24/h1-8H,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394374 (CHEMBL2159813) Show SMILES O=C(N1CCN(Cc2ccc(cc2)-c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-23-9-5-4-8-22(23)25-26-29)28-16-14-27(15-17-28)18-19-10-12-21(13-11-19)20-6-2-1-3-7-20/h1-13H,14-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394357 (CHEMBL2159795) Show SMILES [O-][N+](=O)c1ccc(cc1C(=O)Nc1ccccc1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C24H21N7O4/c32-23(25-17-6-2-1-3-7-17)19-16-18(10-11-21(19)31(34)35)28-12-14-29(15-13-28)24(33)30-22-9-5-4-8-20(22)26-27-30/h1-11,16H,12-15H2,(H,25,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394366 (CHEMBL2159784) Show SMILES [O-][N+](=O)c1ccccc1N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C17H16N6O3/c24-17(22-14-6-2-1-5-13(14)18-19-22)21-11-9-20(10-12-21)15-7-3-4-8-16(15)23(25)26/h1-8H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394389 (CHEMBL2159798) Show SMILES O=C(N1CCN(Cc2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C18H19N5O/c24-18(23-17-9-5-4-8-16(17)19-20-23)22-12-10-21(11-13-22)14-15-6-2-1-3-7-15/h1-9H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394362 (CHEMBL2159788) Show SMILES [O-][N+](=O)c1ccc(cc1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C17H16N6O3/c24-17(22-16-4-2-1-3-15(16)18-19-22)21-11-9-20(10-12-21)13-5-7-14(8-6-13)23(25)26/h1-8H,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394390 (CHEMBL2159797) Show SMILES O=C(N1CCN(CC1)c1ccccc1)n1nnc2ccccc12 Show InChI InChI=1S/C17H17N5O/c23-17(22-16-9-5-4-8-15(16)18-19-22)21-12-10-20(11-13-21)14-6-2-1-3-7-14/h1-9H,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394384 (CHEMBL2159803) Show SMILES Brc1ccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)cc1 Show InChI InChI=1S/C18H18BrN5O/c19-15-7-5-14(6-8-15)13-22-9-11-23(12-10-22)18(25)24-17-4-2-1-3-16(17)20-21-24/h1-8H,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394373 (CHEMBL2159777) Show SMILES O=C(N1CCN(Cc2cccc(c2)-c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-23-12-5-4-11-22(23)25-26-29)28-15-13-27(14-16-28)18-19-7-6-10-21(17-19)20-8-2-1-3-9-20/h1-12,17H,13-16,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394388 (CHEMBL2159799) Show SMILES O=C(N1CCN(C\C=C\c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C20H21N5O/c26-20(25-19-11-5-4-10-18(19)21-22-25)24-15-13-23(14-16-24)12-6-9-17-7-2-1-3-8-17/h1-11H,12-16H2/b9-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394368 (CHEMBL2159782) Show SMILES Fc1ccccc1N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C17H16FN5O/c18-13-5-1-3-7-15(13)21-9-11-22(12-10-21)17(24)23-16-8-4-2-6-14(16)19-20-23/h1-8H,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394372 (CHEMBL2159778) Show SMILES O=C(N1CCN(Cc2ccccc2-c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-23-13-7-6-12-22(23)25-26-29)28-16-14-27(15-17-28)18-20-10-4-5-11-21(20)19-8-2-1-3-9-19/h1-13H,14-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394363 (CHEMBL2159787) Show SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C18H19N5O2/c1-25-15-8-6-14(7-9-15)21-10-12-22(13-11-21)18(24)23-17-5-3-2-4-16(17)19-20-23/h2-9H,10-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394372 (CHEMBL2159778) Show SMILES O=C(N1CCN(Cc2ccccc2-c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-23-13-7-6-12-22(23)25-26-29)28-16-14-27(15-17-28)18-20-10-4-5-11-21(20)19-8-2-1-3-9-19/h1-13H,14-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394388 (CHEMBL2159799) Show SMILES O=C(N1CCN(C\C=C\c2ccccc2)CC1)n1nnc2ccccc12 Show InChI InChI=1S/C20H21N5O/c26-20(25-19-11-5-4-10-18(19)21-22-25)24-15-13-23(14-16-24)12-6-9-17-7-2-1-3-8-17/h1-11H,12-16H2/b9-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394362 (CHEMBL2159788) Show SMILES [O-][N+](=O)c1ccc(cc1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C17H16N6O3/c24-17(22-16-4-2-1-3-15(16)18-19-22)21-11-9-20(10-12-21)13-5-7-14(8-6-13)23(25)26/h1-8H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394375 (CHEMBL2159812) Show SMILES O=C(Nc1ccccc1)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C25H24N6O2/c32-24(26-21-9-2-1-3-10-21)20-8-6-7-19(17-20)18-29-13-15-30(16-14-29)25(33)31-23-12-5-4-11-22(23)27-28-31/h1-12,17H,13-16,18H2,(H,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394378 (CHEMBL2159809) Show SMILES O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C24H28N6O2/c31-23(28-11-4-1-5-12-28)20-8-6-7-19(17-20)18-27-13-15-29(16-14-27)24(32)30-22-10-3-2-9-21(22)25-26-30/h2-3,6-10,17H,1,4-5,11-16,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM60622 (BDBM50300355 | US11753371, Compound JZL-184 | US91...) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394360 (CHEMBL2159790) Show SMILES [O-][N+](=O)c1ccc(cc1C(=O)N1CCCCC1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C23H25N7O4/c31-22(27-10-4-1-5-11-27)18-16-17(8-9-20(18)30(33)34)26-12-14-28(15-13-26)23(32)29-21-7-3-2-6-19(21)24-25-29/h2-3,6-9,16H,1,4-5,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394358 (CHEMBL2159794) Show SMILES [O-][N+](=O)c1ccc(cc1C(=O)NC1CCCCC1)N1CCN(CC1)C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C24H27N7O4/c32-23(25-17-6-2-1-3-7-17)19-16-18(10-11-21(19)31(34)35)28-12-14-29(15-13-28)24(33)30-22-9-5-4-8-20(22)26-27-30/h4-5,8-11,16-17H,1-3,6-7,12-15H2,(H,25,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394381 (CHEMBL2159806) Show SMILES [O-][N+](=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C18H18N6O3/c25-18(23-17-7-2-1-6-16(17)19-20-23)22-10-8-21(9-11-22)13-14-4-3-5-15(12-14)24(26)27/h1-7,12H,8-11,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394376 (CHEMBL2159811) Show SMILES O=C(NC1CCCCC1)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C25H30N6O2/c32-24(26-21-9-2-1-3-10-21)20-8-6-7-19(17-20)18-29-13-15-30(16-14-29)25(33)31-23-12-5-4-11-22(23)27-28-31/h4-8,11-12,17,21H,1-3,9-10,13-16,18H2,(H,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50394378 (CHEMBL2159809) Show SMILES O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 Show InChI InChI=1S/C24H28N6O2/c31-23(28-11-4-1-5-12-28)20-8-6-7-19(17-20)18-27-13-15-29(16-14-27)24(32)30-22-10-3-2-9-21(22)25-26-30/h2-3,6-10,17H,1,4-5,11-16,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
					More data for this Ligand-Target Pair

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