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Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with all data for entry = 50041992   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 6


(Homo sapiens (Human))
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
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CHEMBL
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MCE
KEGG
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PC sid
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PubMed
2.27E+4n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PAH uptake (PAH: 5 uM, indoxyl sulfate:500 uM) in S2 human-OAT1 expressing cells


Eur J Pharmacol 466: 13-20 (2003)


BindingDB Entry DOI: 10.7270/Q23R0V48
More data for this
Ligand-Target Pair
Solute carrier family 22 member 6


(Homo sapiens (Human))
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
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CHEMBL
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MCE
KEGG
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PubMed
2.30E+4n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: uptake&inhibition of PAH in OAT1-S2 cells


Eur J Pharmacol 466: 13-20 (2003)


BindingDB Entry DOI: 10.7270/Q23R0V48
More data for this
Ligand-Target Pair
Solute carrier family 22 member 8


(Homo sapiens (Human))
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
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CHEMBL
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MCE
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PubMed
1.69E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of E1S uptake (E1S: 5 uM, indoxyl sulfate:500 uM) in S2 cells expressing human-OAT3


Eur J Pharmacol 466: 13-20 (2003)


BindingDB Entry DOI: 10.7270/Q23R0V48
More data for this
Ligand-Target Pair
Solute carrier family 22 member 8


(Homo sapiens (Human))
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
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CHEMBL
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MCE
KEGG
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PC sid
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PubMed
1.69E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: uptake&inhibition of estrone sulfate in OAT3-S2 cells


Eur J Pharmacol 466: 13-20 (2003)


BindingDB Entry DOI: 10.7270/Q23R0V48
More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens (Human))
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
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CHEMBL
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MCE
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PC sid
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PubMed
1.81E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: uptake&inhibition of estrone sulfate in OAT4-S2 cells


Eur J Pharmacol 466: 13-20 (2003)


BindingDB Entry DOI: 10.7270/Q23R0V48
More data for this
Ligand-Target Pair
Solute carrier family 22 member 11


(Homo sapiens (Human))
BDBM50420185
PNG
(CHEMBL1233636)
Show SMILES OS(=O)(=O)Oc1c[nH]c2ccccc12
Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12)
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CHEMBL
DrugBank
MCE
KEGG
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PC cid
PC sid
PDB
UniChem

Similars

PubMed
1.81E+5n/an/an/an/an/an/an/an/a



Nagoya University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of E1S uptake (E1S: 5 uM, indoxyl sulfate:500 uM) in S2 cells expressing human-OAT4


Eur J Pharmacol 466: 13-20 (2003)


BindingDB Entry DOI: 10.7270/Q23R0V48
More data for this
Ligand-Target Pair