Compile Data Set for Download or QSAR

Found 34 hits Enz. Inhib. hit(s) with all data for entry = 50002523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459707 (CHEMBL4208452 | US10836764, Compound 115) Show SMILES [H][C@]12CCc3c(Cc4cccc(F)c4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H20FN3/c19-15-3-1-2-13(11-15)10-14-6-7-21-18-17(14)5-4-16-12-20-8-9-22(16)18/h1-3,6-7,11,16,20H,4-5,8-10,12H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	115	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459717 (CHEMBL4209572) Show SMILES [H][C@]12CCc3cccnc3N1CCNC2 |r| Show InChI InChI=1S/C11H15N3/c1-2-9-3-4-10-8-12-6-7-14(10)11(9)13-5-1/h1-2,5,10,12H,3-4,6-8H2/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459709 (CHEMBL4209052 | US10836764, Compound 137) Show SMILES C(C1CCC1)c1ccnc2N3CCNCC3CCc12 Show InChI InChI=1S/C16H23N3/c1-2-12(3-1)10-13-6-7-18-16-15(13)5-4-14-11-17-8-9-19(14)16/h6-7,12,14,17H,1-5,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.02E+3	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459710 (CHEMBL4212834 | US10836764, Compound 128) Show SMILES [H][C@]12CCc3c(Cc4ccc(F)cc4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H20FN3/c19-15-3-1-13(2-4-15)11-14-7-8-21-18-17(14)6-5-16-12-20-9-10-22(16)18/h1-4,7-8,16,20H,5-6,9-12H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459711 (CHEMBL4217846) Show SMILES [H][C@]12CCc3ccncc3N1CCNC2 |r| Show InChI InChI=1S/C11H15N3/c1-2-10-7-13-5-6-14(10)11-8-12-4-3-9(1)11/h3-4,8,10,13H,1-2,5-7H2/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459712 (CHEMBL4218374 | US10836764, Compound 173) Show SMILES [H][C@]12CCc3c(CCC)cncc3N1CCNC2 |r| Show InChI InChI=1S/C14H21N3/c1-2-3-11-8-16-10-14-13(11)5-4-12-9-15-6-7-17(12)14/h8,10,12,15H,2-7,9H2,1H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459713 (CHEMBL4213447 | US10836764, Compound 176) Show SMILES [H][C@]12CCc3c(CC4CCC4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C16H23N3/c1-2-12(3-1)10-13-6-7-18-16-15(13)5-4-14-11-17-8-9-19(14)16/h6-7,12,14,17H,1-5,8-11H2/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.108	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459707 (CHEMBL4208452 | US10836764, Compound 115) Show SMILES [H][C@]12CCc3c(Cc4cccc(F)c4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H20FN3/c19-15-3-1-2-13(11-15)10-14-6-7-21-18-17(14)5-4-16-12-20-8-9-22(16)18/h1-3,6-7,11,16,20H,4-5,8-10,12H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459714 (CHEMBL4204710 | US10836764, Compound 149) Show SMILES [H][C@]12CCc3c(ccnc3N1CCNC2)C1CCC1 |r| Show InChI InChI=1S/C15H21N3/c1-2-11(3-1)13-6-7-17-15-14(13)5-4-12-10-16-8-9-18(12)15/h6-7,11-12,16H,1-5,8-10H2/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	236	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459709 (CHEMBL4209052 | US10836764, Compound 137) Show SMILES C(C1CCC1)c1ccnc2N3CCNCC3CCc12 Show InChI InChI=1S/C16H23N3/c1-2-12(3-1)10-13-6-7-18-16-15(13)5-4-14-11-17-8-9-19(14)16/h6-7,12,14,17H,1-5,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459715 (CHEMBL4213971) Show SMILES [H][C@]12CCc3c(Br)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C11H14BrN3/c12-10-3-4-14-11-9(10)2-1-8-7-13-5-6-15(8)11/h3-4,8,13H,1-2,5-7H2/t8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459716 (CHEMBL4217787 | US10836764, Compound 121) Show SMILES [H][C@]12CCc3c(CC(C)(C)C)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C16H25N3/c1-16(2,3)10-12-6-7-18-15-14(12)5-4-13-11-17-8-9-19(13)15/h6-7,13,17H,4-5,8-11H2,1-3H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459713 (CHEMBL4213447 | US10836764, Compound 176) Show SMILES [H][C@]12CCc3c(CC4CCC4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C16H23N3/c1-2-12(3-1)10-13-6-7-18-16-15(13)5-4-14-11-17-8-9-19(14)16/h6-7,12,14,17H,1-5,8-11H2/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	165	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459711 (CHEMBL4217846) Show SMILES [H][C@]12CCc3ccncc3N1CCNC2 |r| Show InChI InChI=1S/C11H15N3/c1-2-10-7-13-5-6-14(10)11-8-12-4-3-9(1)11/h3-4,8,10,13H,1-2,5-7H2/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	779	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459717 (CHEMBL4209572) Show SMILES [H][C@]12CCc3cccnc3N1CCNC2 |r| Show InChI InChI=1S/C11H15N3/c1-2-9-3-4-10-8-12-6-7-14(10)11(9)13-5-1/h1-2,5,10,12H,3-4,6-8H2/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459715 (CHEMBL4213971) Show SMILES [H][C@]12CCc3c(Br)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C11H14BrN3/c12-10-3-4-14-11-9(10)2-1-8-7-13-5-6-15(8)11/h3-4,8,13H,1-2,5-7H2/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	489	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459710 (CHEMBL4212834 | US10836764, Compound 128) Show SMILES [H][C@]12CCc3c(Cc4ccc(F)cc4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H20FN3/c19-15-3-1-13(2-4-15)11-14-7-8-21-18-17(14)6-5-16-12-20-9-10-22(16)18/h1-4,7-8,16,20H,5-6,9-12H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	307	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459718 (CHEMBL4213379 | US10836764, Compound 106) Show SMILES [H][C@]12CCc3c(Cc4ccccc4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H21N3/c1-2-4-14(5-3-1)12-15-8-9-20-18-17(15)7-6-16-13-19-10-11-21(16)18/h1-5,8-9,16,19H,6-7,10-13H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	758	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459712 (CHEMBL4218374 | US10836764, Compound 173) Show SMILES [H][C@]12CCc3c(CCC)cncc3N1CCNC2 |r| Show InChI InChI=1S/C14H21N3/c1-2-3-11-8-16-10-14-13(11)5-4-12-9-15-6-7-17(12)14/h8,10,12,15H,2-7,9H2,1H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459711 (CHEMBL4217846) Show SMILES [H][C@]12CCc3ccncc3N1CCNC2 |r| Show InChI InChI=1S/C11H15N3/c1-2-10-7-13-5-6-14(10)11-8-12-4-3-9(1)11/h3-4,8,10,13H,1-2,5-7H2/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	329	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459714 (CHEMBL4204710 | US10836764, Compound 149) Show SMILES [H][C@]12CCc3c(ccnc3N1CCNC2)C1CCC1 |r| Show InChI InChI=1S/C15H21N3/c1-2-11(3-1)13-6-7-17-15-14(13)5-4-12-10-16-8-9-18(12)15/h6-7,11-12,16H,1-5,8-10H2/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459709 (CHEMBL4209052 | US10836764, Compound 137) Show SMILES C(C1CCC1)c1ccnc2N3CCNCC3CCc12 Show InChI InChI=1S/C16H23N3/c1-2-12(3-1)10-13-6-7-18-16-15(13)5-4-14-11-17-8-9-19(14)16/h6-7,12,14,17H,1-5,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459716 (CHEMBL4217787 | US10836764, Compound 121) Show SMILES [H][C@]12CCc3c(CC(C)(C)C)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C16H25N3/c1-16(2,3)10-12-6-7-18-15-14(12)5-4-13-11-17-8-9-19(13)15/h6-7,13,17H,4-5,8-11H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459718 (CHEMBL4213379 | US10836764, Compound 106) Show SMILES [H][C@]12CCc3c(Cc4ccccc4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H21N3/c1-2-4-14(5-3-1)12-15-8-9-20-18-17(15)7-6-16-13-19-10-11-21(16)18/h1-5,8-9,16,19H,6-7,10-13H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.116	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459707 (CHEMBL4208452 | US10836764, Compound 115) Show SMILES [H][C@]12CCc3c(Cc4cccc(F)c4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H20FN3/c19-15-3-1-2-13(11-15)10-14-6-7-21-18-17(14)5-4-16-12-20-8-9-22(16)18/h1-3,6-7,11,16,20H,4-5,8-10,12H2/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459710 (CHEMBL4212834 | US10836764, Compound 128) Show SMILES [H][C@]12CCc3c(Cc4ccc(F)cc4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H20FN3/c19-15-3-1-13(2-4-15)11-14-7-8-21-18-17(14)6-5-16-12-20-9-10-22(16)18/h1-4,7-8,16,20H,5-6,9-12H2/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459708 (CHEMBL4206126 | US10836764, Compound 152) Show SMILES [H][C@]12CCc3c(CCC(F)(F)F)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C14H18F3N3/c15-14(16,17)5-3-10-4-6-19-13-12(10)2-1-11-9-18-7-8-20(11)13/h4,6,11,18H,1-3,5,7-9H2/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459717 (CHEMBL4209572) Show SMILES [H][C@]12CCc3cccnc3N1CCNC2 |r| Show InChI InChI=1S/C11H15N3/c1-2-9-3-4-10-8-12-6-7-14(10)11(9)13-5-1/h1-2,5,10,12H,3-4,6-8H2/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459718 (CHEMBL4213379 | US10836764, Compound 106) Show SMILES [H][C@]12CCc3c(Cc4ccccc4)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C18H21N3/c1-2-4-14(5-3-1)12-15-8-9-20-18-17(15)7-6-16-13-19-10-11-21(16)18/h1-5,8-9,16,19H,6-7,10-13H2/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459714 (CHEMBL4204710 | US10836764, Compound 149) Show SMILES [H][C@]12CCc3c(ccnc3N1CCNC2)C1CCC1 |r| Show InChI InChI=1S/C15H21N3/c1-2-11(3-1)13-6-7-17-15-14(13)5-4-12-10-16-8-9-18(12)15/h6-7,11-12,16H,1-5,8-10H2/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50459716 (CHEMBL4217787 | US10836764, Compound 121) Show SMILES [H][C@]12CCc3c(CC(C)(C)C)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C16H25N3/c1-16(2,3)10-12-6-7-18-15-14(12)5-4-13-11-17-8-9-19(13)15/h6-7,13,17H,4-5,8-11H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	478	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2B receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459708 (CHEMBL4206126 | US10836764, Compound 152) Show SMILES [H][C@]12CCc3c(CCC(F)(F)F)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C14H18F3N3/c15-14(16,17)5-3-10-4-6-19-13-12(10)2-1-11-9-18-7-8-20(11)13/h4,6,11,18H,1-3,5,7-9H2/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50459715 (CHEMBL4213971) Show SMILES [H][C@]12CCc3c(Br)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C11H14BrN3/c12-10-3-4-14-11-9(10)2-1-8-7-13-5-6-15(8)11/h3-4,8,13H,1-2,5-7H2/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2C receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50459708 (CHEMBL4206126 | US10836764, Compound 152) Show SMILES [H][C@]12CCc3c(CCC(F)(F)F)ccnc3N1CCNC2 |r| Show InChI InChI=1S/C14H18F3N3/c15-14(16,17)5-3-10-4-6-19-13-12(10)2-1-11-9-18-7-8-20(11)13/h4,6,11,18H,1-3,5,7-9H2/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	980	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Agonist activity at recombinant 5-HT2A receptor (unknown origin) expressed in HEK293 cells assessed as increase in [3H]-inositol phosphate accumulati...				ACS Med Chem Lett 9: 864-865 (2018) Article DOI: 10.1021/acsmedchemlett.8b00328 BindingDB Entry DOI: 10.7270/Q2XS5Z0D
					More data for this Ligand-Target Pair