Compile Data Set for Download or QSAR

Found 52 hits Enz. Inhib. hit(s) with all data for entry = 50003406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50032282 (4-(2-{(E)-3-[1-(1-Propyl-butyl)-1H-indol-5-yl]-but...) Show SMILES CCCC(CCC)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C29H36N2O4/c1-4-9-24(10-5-2)31-17-16-23-20-22(14-15-26(23)31)21(3)19-28(32)30-25-11-6-7-12-27(25)35-18-8-13-29(33)34/h6-7,11-12,14-17,19-20,24H,4-5,8-10,13,18H2,1-3H3,(H,30,32)(H,33,34)/b21-19+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50032297 (4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C35H30F2N2O4/c1-23(21-33(40)38-30-5-2-3-6-32(30)43-20-4-7-34(41)42)26-12-17-31-27(22-26)18-19-39(31)35(24-8-13-28(36)14-9-24)25-10-15-29(37)16-11-25/h2-3,5-6,8-19,21-22,35H,4,7,20H2,1H3,(H,38,40)(H,41,42)/b23-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470304 (CHEMBL98478) Show SMILES C\C(=C/C(=O)Nc1ccc(F)cc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H31FN2O4/c1-24(21-33(39)37-30-16-15-29(36)23-32(30)42-20-8-13-34(40)41)27-14-17-31-28(22-27)18-19-38(31)35(25-9-4-2-5-10-25)26-11-6-3-7-12-26/h2-7,9-12,14-19,21-23,35H,8,13,20H2,1H3,(H,37,39)(H,40,41)/b24-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50032281 (4-(2-{(E)-3-[1-(1-Propyl-pentyl)-1H-indol-5-yl]-bu...) Show SMILES CCCCC(CCC)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C30H38N2O4/c1-4-6-11-25(10-5-2)32-18-17-24-21-23(15-16-27(24)32)22(3)20-29(33)31-26-12-7-8-13-28(26)36-19-9-14-30(34)35/h7-8,12-13,15-18,20-21,25H,4-6,9-11,14,19H2,1-3H3,(H,31,33)(H,34,35)/b22-20+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50032288 (4-{2-[(E)-3-(1-Benzhydryl-1H-indol-5-yl)-but-2-eno...) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H32N2O4/c1-25(23-33(38)36-30-15-8-9-16-32(30)41-22-10-17-34(39)40)28-18-19-31-29(24-28)20-21-37(31)35(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-9,11-16,18-21,23-24,35H,10,17,22H2,1H3,(H,36,38)(H,39,40)/b25-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470291 (CHEMBL95410) Show SMILES CCCCC(C)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C28H34N2O4/c1-4-5-9-21(3)30-16-15-23-19-22(13-14-25(23)30)20(2)18-27(31)29-24-10-6-7-11-26(24)34-17-8-12-28(32)33/h6-7,10-11,13-16,18-19,21H,4-5,8-9,12,17H2,1-3H3,(H,29,31)(H,32,33)/b20-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470283 (CHEMBL421752) Show SMILES CC(C)CC(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C33H36N2O4/c1-23(2)20-30(25-10-5-4-6-11-25)35-18-17-27-22-26(15-16-29(27)35)24(3)21-32(36)34-28-12-7-8-13-31(28)39-19-9-14-33(37)38/h4-8,10-13,15-18,21-23,30H,9,14,19-20H2,1-3H3,(H,34,36)(H,37,38)/b24-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470301 (CHEMBL99824) Show SMILES CCCCC(CC)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C29H36N2O4/c1-4-6-10-24(5-2)31-17-16-23-20-22(14-15-26(23)31)21(3)19-28(32)30-25-11-7-8-12-27(25)35-18-9-13-29(33)34/h7-8,11-12,14-17,19-20,24H,4-6,9-10,13,18H2,1-3H3,(H,30,32)(H,33,34)/b21-19+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470289 (CHEMBL96030) Show SMILES CCCC(C(C)C)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C29H36N2O4/c1-5-9-25(20(2)3)31-16-15-23-19-22(13-14-26(23)31)21(4)18-28(32)30-24-10-6-7-11-27(24)35-17-8-12-29(33)34/h6-7,10-11,13-16,18-20,25H,5,8-9,12,17H2,1-4H3,(H,30,32)(H,33,34)/b21-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470272 (CHEMBL431270) Show SMILES CCCC(C)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C27H32N2O4/c1-4-8-20(3)29-15-14-22-18-21(12-13-24(22)29)19(2)17-26(30)28-23-9-5-6-10-25(23)33-16-7-11-27(31)32/h5-6,9-10,12-15,17-18,20H,4,7-8,11,16H2,1-3H3,(H,28,30)(H,31,32)/b19-17+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50032264 (4-(2-{(E)-3-[1-(1-Isobutyl-3-methyl-butyl)-1H-indo...) Show SMILES CC(C)CC(CC(C)C)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C31H40N2O4/c1-21(2)17-26(18-22(3)4)33-15-14-25-20-24(12-13-28(25)33)23(5)19-30(34)32-27-9-6-7-10-29(27)37-16-8-11-31(35)36/h6-7,9-10,12-15,19-22,26H,8,11,16-18H2,1-5H3,(H,32,34)(H,35,36)/b23-19+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470263 (CHEMBL99811) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C36H31F3N2O4/c1-24(22-33(42)40-30-10-5-6-11-32(30)45-21-7-12-34(43)44)27-15-18-31-28(23-27)19-20-41(31)35(25-8-3-2-4-9-25)26-13-16-29(17-14-26)36(37,38)39/h2-6,8-11,13-20,22-23,35H,7,12,21H2,1H3,(H,40,42)(H,43,44)/b24-22+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470293 (CHEMBL329690) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccc(C)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C37H36N2O4/c1-25-10-14-28(15-11-25)37(29-16-12-26(2)13-17-29)39-21-20-31-24-30(18-19-33(31)39)27(3)23-35(40)38-32-7-4-5-8-34(32)43-22-6-9-36(41)42/h4-5,7-8,10-21,23-24,37H,6,9,22H2,1-3H3,(H,38,40)(H,41,42)/b27-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470268 (CHEMBL319506) Show SMILES COc1ccc(cc1)C(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C36H34N2O5/c1-25(23-34(39)37-31-11-6-7-12-33(31)43-22-8-13-35(40)41)28-16-19-32-29(24-28)20-21-38(32)36(26-9-4-3-5-10-26)27-14-17-30(42-2)18-15-27/h3-7,9-12,14-21,23-24,36H,8,13,22H2,1-2H3,(H,37,39)(H,40,41)/b25-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470260 (CHEMBL99860) Show SMILES CCCC(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C32H34N2O4/c1-3-10-28(24-11-5-4-6-12-24)34-19-18-26-22-25(16-17-29(26)34)23(2)21-31(35)33-27-13-7-8-14-30(27)38-20-9-15-32(36)37/h4-8,11-14,16-19,21-22,28H,3,9-10,15,20H2,1-2H3,(H,33,35)(H,36,37)/b23-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470274 (CHEMBL319549) Show SMILES CCCC(CC)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C28H34N2O4/c1-4-9-23(5-2)30-16-15-22-19-21(13-14-25(22)30)20(3)18-27(31)29-24-10-6-7-11-26(24)34-17-8-12-28(32)33/h6-7,10-11,13-16,18-19,23H,4-5,8-9,12,17H2,1-3H3,(H,29,31)(H,32,33)/b20-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470277 (CHEMBL97506) Show SMILES CCCCC(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C33H36N2O4/c1-3-4-14-29(25-11-6-5-7-12-25)35-20-19-27-23-26(17-18-30(27)35)24(2)22-32(36)34-28-13-8-9-15-31(28)39-21-10-16-33(37)38/h5-9,11-13,15,17-20,22-23,29H,3-4,10,14,16,21H2,1-2H3,(H,34,36)(H,37,38)/b24-22+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470303 (CHEMBL319505) Show SMILES COc1ccc(cc1)C(c1ccc(OC)cc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C37H36N2O6/c1-25(23-35(40)38-32-7-4-5-8-34(32)45-22-6-9-36(41)42)28-14-19-33-29(24-28)20-21-39(33)37(26-10-15-30(43-2)16-11-26)27-12-17-31(44-3)18-13-27/h4-5,7-8,10-21,23-24,37H,6,9,22H2,1-3H3,(H,38,40)(H,41,42)/b25-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470302 (CHEMBL29925) Show SMILES C\C(=C/C(=O)Nc1ccc(C)cc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C36H34N2O4/c1-25-15-17-31(33(22-25)42-21-9-14-35(40)41)37-34(39)23-26(2)29-16-18-32-30(24-29)19-20-38(32)36(27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-13,15-20,22-24,36H,9,14,21H2,1-2H3,(H,37,39)(H,40,41)/b26-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470299 (CHEMBL95946) Show SMILES CC(C)C(C(C)C)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C29H36N2O4/c1-19(2)29(20(3)4)31-15-14-23-18-22(12-13-25(23)31)21(5)17-27(32)30-24-9-6-7-10-26(24)35-16-8-11-28(33)34/h6-7,9-10,12-15,17-20,29H,8,11,16H2,1-5H3,(H,30,32)(H,33,34)/b21-17+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470267 (CHEMBL316858) Show SMILES C\C(=C/C(=O)Nc1cccc(F)c1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H31FN2O4/c1-24(22-32(39)37-30-15-8-14-29(36)35(30)42-21-9-16-33(40)41)27-17-18-31-28(23-27)19-20-38(31)34(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-8,10-15,17-20,22-23,34H,9,16,21H2,1H3,(H,37,39)(H,40,41)/b24-22+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470264 (CHEMBL443496) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1C)c1ccccc1C Show InChI InChI=1S/C37H36N2O4/c1-25-11-4-6-13-30(25)37(31-14-7-5-12-26(31)2)39-21-20-29-24-28(18-19-33(29)39)27(3)23-35(40)38-32-15-8-9-16-34(32)43-22-10-17-36(41)42/h4-9,11-16,18-21,23-24,37H,10,17,22H2,1-3H3,(H,38,40)(H,41,42)/b27-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470292 (CHEMBL100318) Show SMILES CCC(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C31H32N2O4/c1-3-27(23-10-5-4-6-11-23)33-18-17-25-21-24(15-16-28(25)33)22(2)20-30(34)32-26-12-7-8-13-29(26)37-19-9-14-31(35)36/h4-8,10-13,15-18,20-21,27H,3,9,14,19H2,1-2H3,(H,32,34)(H,35,36)/b22-20+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470266 (CHEMBL100314) Show SMILES CC(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C30H30N2O4/c1-21(19-29(33)31-26-11-6-7-12-28(26)36-18-8-13-30(34)35)24-14-15-27-25(20-24)16-17-32(27)22(2)23-9-4-3-5-10-23/h3-7,9-12,14-17,19-20,22H,8,13,18H2,1-2H3,(H,31,33)(H,34,35)/b21-19+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470271 (CHEMBL327722) Show SMILES CCCCC(CCCC)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C31H40N2O4/c1-4-6-11-26(12-7-5-2)33-19-18-25-22-24(16-17-28(25)33)23(3)21-30(34)32-27-13-8-9-14-29(27)37-20-10-15-31(35)36/h8-9,13-14,16-19,21-22,26H,4-7,10-12,15,20H2,1-3H3,(H,32,34)(H,35,36)/b23-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470284 (CHEMBL99473) Show SMILES CCCCCn1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C27H32N2O4/c1-3-4-7-15-29-16-14-22-19-21(12-13-24(22)29)20(2)18-26(30)28-23-9-5-6-10-25(23)33-17-8-11-27(31)32/h5-6,9-10,12-14,16,18-19H,3-4,7-8,11,15,17H2,1-2H3,(H,28,30)(H,31,32)/b20-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470279 (CHEMBL327521) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C35H30Cl2N2O4/c1-23(21-33(40)38-30-5-2-3-6-32(30)43-20-4-7-34(41)42)26-12-17-31-27(22-26)18-19-39(31)35(24-8-13-28(36)14-9-24)25-10-15-29(37)16-11-25/h2-3,5-6,8-19,21-22,35H,4,7,20H2,1H3,(H,38,40)(H,41,42)/b23-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470290 (CHEMBL328182) Show SMILES CC(C)C(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C32H34N2O4/c1-22(2)32(24-10-5-4-6-11-24)34-18-17-26-21-25(15-16-28(26)34)23(3)20-30(35)33-27-12-7-8-13-29(27)38-19-9-14-31(36)37/h4-8,10-13,15-18,20-22,32H,9,14,19H2,1-3H3,(H,33,35)(H,36,37)/b23-20+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470262 (CHEMBL431435) Show SMILES CCCCCC(c1ccccc1)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C34H38N2O4/c1-3-4-6-15-30(26-12-7-5-8-13-26)36-21-20-28-24-27(18-19-31(28)36)25(2)23-33(37)35-29-14-9-10-16-32(29)40-22-11-17-34(38)39/h5,7-10,12-14,16,18-21,23-24,30H,3-4,6,11,15,17,22H2,1-2H3,(H,35,37)(H,38,39)/b25-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470285 (CHEMBL99300) Show SMILES CCCCCC(CCCCC)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C33H44N2O4/c1-4-6-8-13-28(14-9-7-5-2)35-21-20-27-24-26(18-19-30(27)35)25(3)23-32(36)34-29-15-10-11-16-31(29)39-22-12-17-33(37)38/h10-11,15-16,18-21,23-24,28H,4-9,12-14,17,22H2,1-3H3,(H,34,36)(H,37,38)/b25-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470282 (CHEMBL95458) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccncc1 Show InChI InChI=1S/C34H31N3O4/c1-24(22-32(38)36-29-10-5-6-11-31(29)41-21-7-12-33(39)40)27-13-14-30-28(23-27)17-20-37(30)34(25-8-3-2-4-9-25)26-15-18-35-19-16-26/h2-6,8-11,13-20,22-23,34H,7,12,21H2,1H3,(H,36,38)(H,39,40)/b24-22+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470294 (CHEMBL101260) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccn1 Show InChI InChI=1S/C34H31N3O4/c1-24(22-32(38)36-28-12-5-6-14-31(28)41-21-9-15-33(39)40)26-16-17-30-27(23-26)18-20-37(30)34(25-10-3-2-4-11-25)29-13-7-8-19-35-29/h2-8,10-14,16-20,22-23,34H,9,15,21H2,1H3,(H,36,38)(H,39,40)/b24-22+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470275 (CHEMBL99449) Show SMILES C\C(=C/C(=O)Nc1ccccc1SCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H32N2O3S/c1-25(23-33(38)36-30-15-8-9-16-32(30)41-22-10-17-34(39)40)28-18-19-31-29(24-28)20-21-37(31)35(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-9,11-16,18-21,23-24,35H,10,17,22H2,1H3,(H,36,38)(H,39,40)/b25-23+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470273 (CHEMBL95588) Show SMILES CCCCn1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C26H30N2O4/c1-3-4-14-28-15-13-21-18-20(11-12-23(21)28)19(2)17-25(29)27-22-8-5-6-9-24(22)32-16-7-10-26(30)31/h5-6,8-9,11-13,15,17-18H,3-4,7,10,14,16H2,1-2H3,(H,27,29)(H,30,31)/b19-17+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470298 (CHEMBL318402) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(ccc2c1)C(c1ccccc1)c1cccnc1 Show InChI InChI=1S/C34H31N3O4/c1-24(21-32(38)36-29-12-5-6-13-31(29)41-20-8-14-33(39)40)26-15-16-30-27(22-26)17-19-37(30)34(25-9-3-2-4-10-25)28-11-7-18-35-23-28/h2-7,9-13,15-19,21-23,34H,8,14,20H2,1H3,(H,36,38)(H,39,40)/b24-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50032315 (4-{2-[(E)-3-(1-Benzyl-1H-indol-5-yl)-but-2-enoylam...) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccccc3)ccc2c1 Show InChI InChI=1S/C29H28N2O4/c1-21(18-28(32)30-25-10-5-6-11-27(25)35-17-7-12-29(33)34)23-13-14-26-24(19-23)15-16-31(26)20-22-8-3-2-4-9-22/h2-6,8-11,13-16,18-19H,7,12,17,20H2,1H3,(H,30,32)(H,33,34)/b21-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470281 (CHEMBL95513) Show SMILES CCC(C)n1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C26H30N2O4/c1-4-19(3)28-14-13-21-17-20(11-12-23(21)28)18(2)16-25(29)27-22-8-5-6-9-24(22)32-15-7-10-26(30)31/h5-6,8-9,11-14,16-17,19H,4,7,10,15H2,1-3H3,(H,27,29)(H,30,31)/b18-16+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470278 (CHEMBL317384) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccccc3C)ccc2c1 Show InChI InChI=1S/C30H30N2O4/c1-21-8-3-4-9-25(21)20-32-16-15-24-19-23(13-14-27(24)32)22(2)18-29(33)31-26-10-5-6-11-28(26)36-17-7-12-30(34)35/h3-6,8-11,13-16,18-19H,7,12,17,20H2,1-2H3,(H,31,33)(H,34,35)/b22-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470269 (CHEMBL99804) Show SMILES CCCCCCn1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C28H34N2O4/c1-3-4-5-8-16-30-17-15-23-20-22(13-14-25(23)30)21(2)19-27(31)29-24-10-6-7-11-26(24)34-18-9-12-28(32)33/h6-7,10-11,13-15,17,19-20H,3-5,8-9,12,16,18H2,1-2H3,(H,29,31)(H,32,33)/b21-19+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470280 (CHEMBL97093) Show SMILES Cc1ccccc1.C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(CC(C)(C)C)ccc2c1 Show InChI InChI=1S/C27H32N2O4/c1-19(20-11-12-23-21(17-20)13-14-29(23)18-27(2,3)4)16-25(30)28-22-8-5-6-9-24(22)33-15-7-10-26(31)32/h5-6,8-9,11-14,16-17H,7,10,15,18H2,1-4H3,(H,28,30)(H,31,32)/b19-16+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470270 (CHEMBL97379) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccc(C)cc3)ccc2c1 Show InChI InChI=1S/C30H30N2O4/c1-21-9-11-23(12-10-21)20-32-16-15-25-19-24(13-14-27(25)32)22(2)18-29(33)31-26-6-3-4-7-28(26)36-17-5-8-30(34)35/h3-4,6-7,9-16,18-19H,5,8,17,20H2,1-2H3,(H,31,33)(H,34,35)/b22-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470261 (CHEMBL99450) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccc(F)cc3)ccc2c1 Show InChI InChI=1S/C29H27FN2O4/c1-20(17-28(33)31-25-5-2-3-6-27(25)36-16-4-7-29(34)35)22-10-13-26-23(18-22)14-15-32(26)19-21-8-11-24(30)12-9-21/h2-3,5-6,8-15,17-18H,4,7,16,19H2,1H3,(H,31,33)(H,34,35)/b20-17+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470288 (CHEMBL95952) Show SMILES CCCCc1ccc(Cn2ccc3cc(ccc23)C(\C)=C\C(=O)Nc2ccccc2OCCCC(O)=O)cc1 Show InChI InChI=1S/C33H36N2O4/c1-3-4-8-25-12-14-26(15-13-25)23-35-19-18-28-22-27(16-17-30(28)35)24(2)21-32(36)34-29-9-5-6-10-31(29)39-20-7-11-33(37)38/h5-6,9-10,12-19,21-22H,3-4,7-8,11,20,23H2,1-2H3,(H,34,36)(H,37,38)/b24-21+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470296 (CHEMBL95833) Show SMILES CCCCCCCn1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C29H36N2O4/c1-3-4-5-6-9-17-31-18-16-24-21-23(14-15-26(24)31)22(2)20-28(32)30-25-11-7-8-12-27(25)35-19-10-13-29(33)34/h7-8,11-12,14-16,18,20-21H,3-6,9-10,13,17,19H2,1-2H3,(H,30,32)(H,33,34)/b22-20+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470265 (CHEMBL97248) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1ccc2cc(ccc12)-[#6](\[#6])=[#6]\[#6](=O)-[#7]-c1ccccc1-[#8]-[#6]-[#6]-[#6]-[#6](-[#8])=O Show InChI InChI=1S/C27H30N2O4/c1-19(2)12-14-29-15-13-22-18-21(10-11-24(22)29)20(3)17-26(30)28-23-7-4-5-8-25(23)33-16-6-9-27(31)32/h4-5,7-8,10-13,15,17-18H,6,9,14,16H2,1-3H3,(H,28,30)(H,31,32)/b20-17+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470297 (CHEMBL414225) Show SMILES CC(C)Cn1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C26H30N2O4/c1-18(2)17-28-13-12-21-16-20(10-11-23(21)28)19(3)15-25(29)27-22-7-4-5-8-24(22)32-14-6-9-26(30)31/h4-5,7-8,10-13,15-16,18H,6,9,14,17H2,1-3H3,(H,27,29)(H,30,31)/b19-15+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470300 (CHEMBL99522) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccc(cc3)C(C)(C)C)ccc2c1 Show InChI InChI=1S/C33H36N2O4/c1-23(20-31(36)34-28-8-5-6-9-30(28)39-19-7-10-32(37)38)25-13-16-29-26(21-25)17-18-35(29)22-24-11-14-27(15-12-24)33(2,3)4/h5-6,8-9,11-18,20-21H,7,10,19,22H2,1-4H3,(H,34,36)(H,37,38)/b23-20+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470287 (CHEMBL95866) Show SMILES CCCn1ccc2cc(ccc12)C(\C)=C\C(=O)Nc1ccccc1OCCCC(O)=O Show InChI InChI=1S/C25H28N2O4/c1-3-13-27-14-12-20-17-19(10-11-22(20)27)18(2)16-24(28)26-21-7-4-5-8-23(21)31-15-6-9-25(29)30/h4-5,7-8,10-12,14,16-17H,3,6,9,13,15H2,1-2H3,(H,26,28)(H,29,30)/b18-16+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470286 (CHEMBL95707) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3cccc(C)c3)ccc2c1 Show InChI InChI=1S/C30H30N2O4/c1-21-7-5-8-23(17-21)20-32-15-14-25-19-24(12-13-27(25)32)22(2)18-29(33)31-26-9-3-4-10-28(26)36-16-6-11-30(34)35/h3-5,7-10,12-15,17-19H,6,11,16,20H2,1-2H3,(H,31,33)(H,34,35)/b22-18+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2 (Rattus norvegicus)	BDBM50470295 (CHEMBL95409) Show SMILES C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccc(cc3)C(F)(F)F)ccc2c1 Show InChI InChI=1S/C30H27F3N2O4/c1-20(17-28(36)34-25-5-2-3-6-27(25)39-16-4-7-29(37)38)22-10-13-26-23(18-22)14-15-35(26)19-21-8-11-24(12-9-21)30(31,32)33/h2-3,5-6,8-15,17-18H,4,7,16,19H2,1H3,(H,34,36)(H,37,38)/b20-17+	MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase in prostates from male rats				J Med Chem 38: 2887-92 (1995) Article DOI: 10.1021/jm00015a011 BindingDB Entry DOI: 10.7270/Q2B27Z0N
					More data for this Ligand-Target Pair

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