Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with all data for entry = 50003574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473230 (CHEMBL47313) Show SMILES C(Cc1ccccc1)[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:17| Show InChI InChI=1S/C17H24N2O/c1-2-6-14(7-3-1)10-11-15-8-4-5-9-16(15)19-17-18-12-13-20-17/h1-3,6-7,15-16H,4-5,8-13H2,(H,18,19)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473228 (AGN-190837 | CHEMBL297752) Show SMILES CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:11| Show InChI InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473228 (AGN-190837 | CHEMBL297752) Show SMILES CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:11| Show InChI InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473230 (CHEMBL47313) Show SMILES C(Cc1ccccc1)[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:17| Show InChI InChI=1S/C17H24N2O/c1-2-6-14(7-3-1)10-11-15-8-4-5-9-16(15)19-17-18-12-13-20-17/h1-3,6-7,15-16H,4-5,8-13H2,(H,18,19)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473230 (CHEMBL47313) Show SMILES C(Cc1ccccc1)[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:17| Show InChI InChI=1S/C17H24N2O/c1-2-6-14(7-3-1)10-11-15-8-4-5-9-16(15)19-17-18-12-13-20-17/h1-3,6-7,15-16H,4-5,8-13H2,(H,18,19)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473229 (CHEMBL295186) Show SMILES C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1 |t:11,THB:8:7:6:3.4| Show InChI InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473227 (CHEMBL50720) Show SMILES C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1 |t:10| Show InChI InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473226 (CHEMBL297827) Show SMILES C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:20,THB:16:15:14:12.11| Show InChI InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473225 (CHEMBL297228) Show SMILES C1CN=C(N[C@H]2CCCC[C@@H]2c2ccccc2)O1 |t:2| Show InChI InChI=1S/C15H20N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)17-15-16-10-11-18-15/h1-3,6-7,13-14H,4-5,8-11H2,(H,16,17)/t13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473232 (CHEMBL50719) Show SMILES C([C@H]1CCCC[C@@H]1NC1=NCCO1)c1ccccc1 |t:9| Show InChI InChI=1S/C16H22N2O/c1-2-6-13(7-3-1)12-14-8-4-5-9-15(14)18-16-17-10-11-19-16/h1-3,6-7,14-15H,4-5,8-12H2,(H,17,18)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473225 (CHEMBL297228) Show SMILES C1CN=C(N[C@H]2CCCC[C@@H]2c2ccccc2)O1 |t:2| Show InChI InChI=1S/C15H20N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)17-15-16-10-11-18-15/h1-3,6-7,13-14H,4-5,8-11H2,(H,16,17)/t13-,14+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473228 (AGN-190837 | CHEMBL297752) Show SMILES CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:11| Show InChI InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant determined using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473231 (CHEMBL48341) Show SMILES C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1 |t:12,THB:9:8:7:5.4| Show InChI InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473227 (CHEMBL50720) Show SMILES C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1 |t:10| Show InChI InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473227 (CHEMBL50720) Show SMILES C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1 |t:10| Show InChI InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473232 (CHEMBL50719) Show SMILES C([C@H]1CCCC[C@@H]1NC1=NCCO1)c1ccccc1 |t:9| Show InChI InChI=1S/C16H22N2O/c1-2-6-13(7-3-1)12-14-8-4-5-9-15(14)18-16-17-10-11-19-16/h1-3,6-7,14-15H,4-5,8-12H2,(H,17,18)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473229 (CHEMBL295186) Show SMILES C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1 |t:11,THB:8:7:6:3.4| Show InChI InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473225 (CHEMBL297228) Show SMILES C1CN=C(N[C@H]2CCCC[C@@H]2c2ccccc2)O1 |t:2| Show InChI InChI=1S/C15H20N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)17-15-16-10-11-18-15/h1-3,6-7,13-14H,4-5,8-11H2,(H,16,17)/t13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473232 (CHEMBL50719) Show SMILES C([C@H]1CCCC[C@@H]1NC1=NCCO1)c1ccccc1 |t:9| Show InChI InChI=1S/C16H22N2O/c1-2-6-13(7-3-1)12-14-8-4-5-9-15(14)18-16-17-10-11-19-16/h1-3,6-7,14-15H,4-5,8-12H2,(H,17,18)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473229 (CHEMBL295186) Show SMILES C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1 |t:11,THB:8:7:6:3.4| Show InChI InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473226 (CHEMBL297827) Show SMILES C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:20,THB:16:15:14:12.11| Show InChI InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473226 (CHEMBL297827) Show SMILES C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:20,THB:16:15:14:12.11| Show InChI InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473231 (CHEMBL48341) Show SMILES C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1 |t:12,THB:9:8:7:5.4| Show InChI InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473231 (CHEMBL48341) Show SMILES C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1 |t:12,THB:9:8:7:5.4| Show InChI InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2A adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473228 (AGN-190837 | CHEMBL297752) Show SMILES CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:11| Show InChI InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2C adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473227 (CHEMBL50720) Show SMILES C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1 |t:10| Show InChI InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473226 (CHEMBL297827) Show SMILES C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:20,THB:16:15:14:12.11| Show InChI InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473228 (AGN-190837 | CHEMBL297752) Show SMILES CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:11| Show InChI InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2A adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473231 (CHEMBL48341) Show SMILES C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1 |t:12,THB:9:8:7:5.4| Show InChI InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2A adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473231 (CHEMBL48341) Show SMILES C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1 |t:12,THB:9:8:7:5.4| Show InChI InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	562	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2B adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473226 (CHEMBL297827) Show SMILES C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:20,THB:16:15:14:12.11| Show InChI InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2A adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50473228 (AGN-190837 | CHEMBL297752) Show SMILES CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 |t:11| Show InChI InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2B adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50473229 (CHEMBL295186) Show SMILES C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1 |t:11,THB:8:7:6:3.4| Show InChI InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair