Compile Data Set for Download or QSAR

Found 195 hits Enz. Inhib. hit(s) with all data for entry = 50007048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505700 (CHEMBL4442460) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C28H35N5O2/c1-35-27-16-9-8-15-26(27)32-21-19-31(20-22-32)18-10-17-29-28(34)30-33(25-13-6-3-7-14-25)23-24-11-4-2-5-12-24/h2-9,11-16H,10,17-23H2,1H3,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505701 (CHEMBL4544086) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(25-8-3-2-4-9-25)22-23-12-14-24(29)15-13-23/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505688 (CHEMBL4563944) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM85093 (CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50505701 (CHEMBL4544086) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(25-8-3-2-4-9-25)22-23-12-14-24(29)15-13-23/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from alpha1A adrenergic receptor (unknown origin)				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50505700 (CHEMBL4442460) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C28H35N5O2/c1-35-27-16-9-8-15-26(27)32-21-19-31(20-22-32)18-10-17-29-28(34)30-33(25-13-6-3-7-14-25)23-24-11-4-2-5-12-24/h2-9,11-16H,10,17-23H2,1H3,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from alpha1A adrenergic receptor (unknown origin)				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505709 (CHEMBL4460743) Show SMILES COc1ccc(cc1)N(Cc1ccccc1)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H37N5O3/c1-36-26-15-13-25(14-16-26)34(23-24-9-4-3-5-10-24)31-29(35)30-17-8-18-32-19-21-33(22-20-32)27-11-6-7-12-28(27)37-2/h3-7,9-16H,8,17-23H2,1-2H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50058225 (CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...) Show SMILES Cc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N Show InChI InChI=1S/C20H22N4O/c1-16-5-4-7-17(13-16)20(25)22-15-23-9-11-24(12-10-23)19-8-3-2-6-18(19)14-21/h2-8,13H,9-12,15H2,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505710 (CHEMBL4434714) Show SMILES COc1ccc(cc1)N(Cc1ccccc1F)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H36FN5O3/c1-37-25-14-12-24(13-15-25)35(22-23-8-3-4-9-26(23)30)32-29(36)31-16-7-17-33-18-20-34(21-19-33)27-10-5-6-11-28(27)38-2/h3-6,8-15H,7,16-22H2,1-2H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505707 (CHEMBL4570073) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2F)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C28H33ClFN5O2/c1-37-27-10-5-4-9-26(27)34-19-17-33(18-20-34)16-6-15-31-28(36)32-35(24-13-11-23(29)12-14-24)21-22-7-2-3-8-25(22)30/h2-5,7-14H,6,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505690 (CHEMBL4582096) Show SMILES COc1ccc(cc1)N(Cc1ccc(F)cc1)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H36FN5O3/c1-37-26-14-12-25(13-15-26)35(22-23-8-10-24(30)11-9-23)32-29(36)31-16-5-17-33-18-20-34(21-19-33)27-6-3-4-7-28(27)38-2/h3-4,6-15H,5,16-22H2,1-2H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505689 (CHEMBL4470231) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C28H34ClN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50097665 (CHEMBL3590077) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\N=N\c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H28FN5O2/c1-30-21-7-3-2-6-20(21)28-16-14-27(15-17-28)13-5-4-12-24-22(29)26-25-19-10-8-18(23)9-11-19/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,29)/b26-25+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D3 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505696 (CHEMBL4467437) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2F)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C28H33BrFN5O2/c1-37-27-10-5-4-9-26(27)34-19-17-33(18-20-34)16-6-15-31-28(36)32-35(24-13-11-23(29)12-14-24)21-22-7-2-3-8-25(22)30/h2-5,7-14H,6,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505722 (CHEMBL4439644) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C28H34BrN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505705 (CHEMBL4442470) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2F)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H33F2N5O2/c1-37-27-10-5-4-9-26(27)34-19-17-33(18-20-34)16-6-15-31-28(36)32-35(24-13-11-23(29)12-14-24)21-22-7-2-3-8-25(22)30/h2-5,7-14H,6,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505721 (CHEMBL4437233) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2cccc(F)c2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H33F2N5O2/c1-37-27-9-3-2-8-26(27)34-18-16-33(17-19-34)15-5-14-31-28(36)32-35(25-12-10-23(29)11-13-25)21-22-6-4-7-24(30)20-22/h2-4,6-13,20H,5,14-19,21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505688 (CHEMBL4563944) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505694 (CHEMBL4448166) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C29H36FN5O2/c1-37-28-12-6-5-11-27(28)34-21-19-33(20-22-34)18-8-7-17-31-29(36)32-35(23-24-9-3-2-4-10-24)26-15-13-25(30)14-16-26/h2-6,9-16H,7-8,17-23H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505706 (CHEMBL4463200) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H33F2N5O2/c1-37-27-6-3-2-5-26(27)34-19-17-33(18-20-34)16-4-15-31-28(36)32-35(25-13-11-24(30)12-14-25)21-22-7-9-23(29)10-8-22/h2-3,5-14H,4,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505695 (CHEMBL4550633) Show SMILES COc1cccc(CN(NC(=O)NCCCN2CCN(CC2)c2ccccc2OC)c2ccc(F)cc2)c1 Show InChI InChI=1S/C29H36FN5O3/c1-37-26-8-5-7-23(21-26)22-35(25-13-11-24(30)12-14-25)32-29(36)31-15-6-16-33-17-19-34(20-18-33)27-9-3-4-10-28(27)38-2/h3-5,7-14,21H,6,15-20,22H2,1-2H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505697 (CHEMBL4454096) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(cc2)-c2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C34H38FN5O2/c1-42-33-11-6-5-10-32(33)39-24-22-38(23-25-39)21-7-20-36-34(41)37-40(31-18-16-30(35)17-19-31)26-27-12-14-29(15-13-27)28-8-3-2-4-9-28/h2-6,8-19H,7,20-26H2,1H3,(H2,36,37,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505698 (CHEMBL4585384) Show SMILES COc1ccc(cc1)N(Cc1cccc(F)c1)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H36FN5O3/c1-37-26-13-11-25(12-14-26)35(22-23-7-5-8-24(30)21-23)32-29(36)31-15-6-16-33-17-19-34(20-18-33)27-9-3-4-10-28(27)38-2/h3-5,7-14,21H,6,15-20,22H2,1-2H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505688 (CHEMBL4563944) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2L receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505702 (CHEMBL4465002) Show SMILES COc1ccccc1N1CCN(CCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C27H32FN5O2/c1-35-26-10-6-5-9-25(26)32-19-17-31(18-20-32)16-15-29-27(34)30-33(21-22-7-3-2-4-8-22)24-13-11-23(28)12-14-24/h2-14H,15-21H2,1H3,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505713 (CHEMBL4587645) Show SMILES Clc1ccc(cc1)N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H32ClN5O/c28-24-12-14-25(15-13-24)32-20-18-31(19-21-32)17-7-16-29-27(34)30-33(26-10-5-2-6-11-26)22-23-8-3-1-4-9-23/h1-6,8-15H,7,16-22H2,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505717 (CHEMBL4583596) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(cc2)C#N)c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C29H32Cl2N6O2/c1-39-28-6-3-2-5-27(28)36-17-15-35(16-18-36)14-4-13-33-29(38)34-37(26-12-11-24(30)19-25(26)31)21-23-9-7-22(20-32)8-10-23/h2-3,5-12,19H,4,13-18,21H2,1H3,(H2,33,34,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505714 (CHEMBL4476278) Show SMILES Brc1ccc(cc1)N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H32BrN5O/c28-24-12-14-25(15-13-24)32-20-18-31(19-21-32)17-7-16-29-27(34)30-33(26-10-5-2-6-11-26)22-23-8-3-1-4-9-23/h1-6,8-15H,7,16-22H2,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505708 (CHEMBL4475042) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C28H33Cl2N5O2/c1-37-27-11-6-5-10-26(27)34-18-16-33(17-19-34)15-7-14-31-28(36)32-35(21-22-8-3-2-4-9-22)25-13-12-23(29)20-24(25)30/h2-6,8-13,20H,7,14-19,21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505703 (CHEMBL4520460) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(cc2)C#N)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C29H33FN6O2/c1-38-28-6-3-2-5-27(28)35-19-17-34(18-20-35)16-4-15-32-29(37)33-36(26-13-11-25(30)12-14-26)22-24-9-7-23(21-31)8-10-24/h2-3,5-14H,4,15-20,22H2,1H3,(H2,32,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505712 (CHEMBL4445706) Show SMILES COc1ccc(cc1)N(Cc1ccc(cc1)C#N)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C30H36N6O3/c1-38-27-14-12-26(13-15-27)36(23-25-10-8-24(22-31)9-11-25)33-30(37)32-16-5-17-34-18-20-35(21-19-34)28-6-3-4-7-29(28)39-2/h3-4,6-15H,5,16-21,23H2,1-2H3,(H2,32,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50505700 (CHEMBL4442460) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C28H35N5O2/c1-35-27-16-9-8-15-26(27)32-21-19-31(20-22-32)18-10-17-29-28(34)30-33(25-13-6-3-7-14-25)23-24-11-4-2-5-12-24/h2-9,11-16H,10,17-23H2,1H3,(H2,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] WAY100635 from 5HT1A receptor (unknown origin)				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505720 (CHEMBL4589982) Show SMILES Fc1ccc(CN(NC(=O)NCCCN2CCN(CC2)c2ccc(Cl)cc2)c2ccccc2)cc1 Show InChI InChI=1S/C27H31ClFN5O/c28-23-9-13-25(14-10-23)33-19-17-32(18-20-33)16-4-15-30-27(35)31-34(26-5-2-1-3-6-26)21-22-7-11-24(29)12-8-22/h1-3,5-14H,4,15-21H2,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505699 (CHEMBL4443944) Show SMILES O=C(NCCCN1CCN(CC1)c1ncccn1)NN(Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H31N7O/c33-25(29-32(23-11-5-2-6-12-23)21-22-9-3-1-4-10-22)28-15-8-16-30-17-19-31(20-18-30)24-26-13-7-14-27-24/h1-7,9-14H,8,15-21H2,(H2,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505709 (CHEMBL4460743) Show SMILES COc1ccc(cc1)N(Cc1ccccc1)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H37N5O3/c1-36-26-15-13-25(14-16-26)34(23-24-9-4-3-5-10-24)31-29(35)30-17-8-18-32-19-21-33(22-20-32)27-11-6-7-12-28(27)37-2/h3-7,9-16H,8,17-23H2,1-2H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505710 (CHEMBL4434714) Show SMILES COc1ccc(cc1)N(Cc1ccccc1F)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H36FN5O3/c1-37-25-14-12-24(13-15-25)35(22-23-8-3-4-9-26(23)30)32-29(36)31-16-7-17-33-18-20-34(21-19-33)27-10-5-6-11-28(27)38-2/h3-6,8-15H,7,16-22H2,1-2H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505715 (CHEMBL4567758) Show SMILES Fc1ccc(CN(NC(=O)NCCCN2CCN(CC2)c2ncccn2)c2ccccc2)cc1 Show InChI InChI=1S/C25H30FN7O/c26-22-10-8-21(9-11-22)20-33(23-6-2-1-3-7-23)30-25(34)29-14-5-15-31-16-18-32(19-17-31)24-27-12-4-13-28-24/h1-4,6-13H,5,14-20H2,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505704 (CHEMBL4534703) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)\N=N\c2ccc(F)cc2)CC1 Show InChI InChI=1S/C21H26FN5O2/c1-29-20-6-3-2-5-19(20)27-15-13-26(14-16-27)12-4-11-23-21(28)25-24-18-9-7-17(22)8-10-18/h2-3,5-10H,4,11-16H2,1H3,(H,23,28)/b25-24+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505723 (CHEMBL4572646) Show SMILES Ic1ccc(cc1)N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H32IN5O/c28-24-12-14-25(15-13-24)32-20-18-31(19-21-32)17-7-16-29-27(34)30-33(26-10-5-2-6-11-26)22-23-8-3-1-4-9-23/h1-6,8-15H,7,16-22H2,(H2,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505696 (CHEMBL4467437) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2F)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C28H33BrFN5O2/c1-37-27-10-5-4-9-26(27)34-19-17-33(18-20-34)16-6-15-31-28(36)32-35(24-13-11-23(29)12-14-24)21-22-7-2-3-8-25(22)30/h2-5,7-14H,6,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505689 (CHEMBL4470231) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C28H34ClN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505708 (CHEMBL4475042) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C28H33Cl2N5O2/c1-37-27-11-6-5-10-26(27)34-18-16-33(17-19-34)15-7-14-31-28(36)32-35(21-22-8-3-2-4-9-22)25-13-12-23(29)20-24(25)30/h2-6,8-13,20H,7,14-19,21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50505688 (CHEMBL4563944) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D3 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505707 (CHEMBL4570073) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2F)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C28H33ClFN5O2/c1-37-27-10-5-4-9-26(27)34-19-17-33(18-20-34)16-6-15-31-28(36)32-35(24-13-11-23(29)12-14-24)21-22-7-2-3-8-25(22)30/h2-5,7-14H,6,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505716 (CHEMBL4536530) Show SMILES Brc1ccc(cc1)N1CCN(CCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C26H30BrN5O/c27-23-11-13-24(14-12-23)31-19-17-30(18-20-31)16-15-28-26(33)29-32(25-9-5-2-6-10-25)21-22-7-3-1-4-8-22/h1-14H,15-21H2,(H2,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505706 (CHEMBL4463200) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H33F2N5O2/c1-37-27-6-3-2-5-26(27)34-19-17-33(18-20-34)16-4-15-31-28(36)32-35(25-13-11-24(30)12-14-25)21-22-7-9-23(29)10-8-22/h2-3,5-14H,4,15-21H2,1H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505689 (CHEMBL4470231) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C28H34ClN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2L receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50505711 (CHEMBL4442419) Show SMILES COc1ccc(cc1)N(Cc1cccc(OC)c1)NC(=O)NCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C30H39N5O4/c1-37-26-14-12-25(13-15-26)35(23-24-8-6-9-27(22-24)38-2)32-30(36)31-16-7-17-33-18-20-34(21-19-33)28-10-4-5-11-29(28)39-3/h4-6,8-15,22H,7,16-21,23H2,1-3H3,(H2,31,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50505701 (CHEMBL4544086) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1 Show InChI InChI=1S/C28H34FN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(25-8-3-2-4-9-25)22-23-12-14-24(29)15-13-23/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] WAY100635 from 5HT1A receptor (unknown origin)				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50505722 (CHEMBL4439644) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C28H34BrN5O2/c1-36-27-11-6-5-10-26(27)33-20-18-32(19-21-33)17-7-16-30-28(35)31-34(22-23-8-3-2-4-9-23)25-14-12-24(29)13-15-25/h2-6,8-15H,7,16-22H2,1H3,(H2,30,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay				J Med Chem 62: 9658-9679 (2019) Article DOI: 10.1021/acs.jmedchem.9b01085 BindingDB Entry DOI: 10.7270/Q2GB27BJ
					More data for this Ligand-Target Pair

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