Found 32 hits Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM85093' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement. |
J Med Chem 47: 2348-55 (2004)
Article DOI: 10.1021/jm0305669
BindingDB Entry DOI: 10.7270/Q2M61M03 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme
Curated by ChEMBL
| Assay Description
Binding affinity towards human dopamine receptor D4 |
J Med Chem 44: 477-501 (2001)
BindingDB Entry DOI: 10.7270/Q24Q7VQH |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center , Omaha, Nebraska 68198-6125, United States.
Curated by ChEMBL
| Assay Description
Inhibition of human dopamine D4 receptor |
J Med Chem 60: 7233-7243 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00151
BindingDB Entry DOI: 10.7270/Q2P84FBZ |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University
Curated by ChEMBL
| Assay Description
Binding affinity for dopamine D4 receptor |
Bioorg Med Chem Lett 14: 5739-42 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.046
BindingDB Entry DOI: 10.7270/Q28K79VJ |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description
Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 17: 1716-23 (2009)
Article DOI: 10.1016/j.bmc.2008.12.054
BindingDB Entry DOI: 10.7270/Q2NG4QGT |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description
In vitro binding affinity to human Dopamine receptor D4 |
Bioorg Med Chem Lett 11: 1375-7 (2001)
BindingDB Entry DOI: 10.7270/Q28C9VHC |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
| Assay Description
Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cells |
Bioorg Med Chem Lett 9: 585-8 (1999)
BindingDB Entry DOI: 10.7270/Q2NV9HD4 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitá di Bari
Curated by ChEMBL
| Assay Description
In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand. |
J Med Chem 41: 4903-9 (1998)
Article DOI: 10.1021/jm981041x
BindingDB Entry DOI: 10.7270/Q2S46R3V |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | Reactome pathway
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026
BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity towards cloned human Dopamine receptor D4 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligand |
J Med Chem 39: 1941-2 (1996)
Article DOI: 10.1021/jm9600712
BindingDB Entry DOI: 10.7270/Q2MW2G6D |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Erlangen-N£rnberg
Curated by ChEMBL
| Assay Description
Binding affinity evaluated for the displacement of [3H]spiperone against human dopamine receptor D4 |
Bioorg Med Chem Lett 9: 97-102 (1999)
BindingDB Entry DOI: 10.7270/Q20Z73SG |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.617 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description
Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cells |
J Med Chem 44: 1151-7 (2001)
Article DOI: 10.1021/jm001055e
BindingDB Entry DOI: 10.7270/Q2959M91 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description
In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement. |
Bioorg Med Chem Lett 12: 633-6 (2002)
BindingDB Entry DOI: 10.7270/Q2JM2B5X |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander-Universit£t Erlangen-N£rnberg
Curated by ChEMBL
| Assay Description
Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay |
J Med Chem 62: 9658-9679 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01085
BindingDB Entry DOI: 10.7270/Q2GB27BJ |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
| Assay Description
In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement. |
Bioorg Med Chem Lett 8: 1499-502 (1999)
BindingDB Entry DOI: 10.7270/Q2WH2P54 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 0.910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement. |
J Med Chem 42: 5181-7 (2000)
BindingDB Entry DOI: 10.7270/Q23T9HZ0 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ACADIA Pharmaceuticals
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 315: 1278-87 (2005)
Article DOI: 10.1124/jpet.105.092155
BindingDB Entry DOI: 10.7270/Q2Z60MNB |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Scuola di Scienze del Farmaco e dei Prodotti della Salute , Università di Camerino , Via S. Agostino 1 , 62032 Camerino , Italy.
Curated by ChEMBL
| Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting method |
J Med Chem 61: 3712-3725 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00265
BindingDB Entry DOI: 10.7270/Q20K2C2P |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00840
BindingDB Entry DOI: 10.7270/Q2ST7TTC |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | Reactome pathway
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| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description
In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperone |
Bioorg Med Chem Lett 11: 1375-7 (2001)
BindingDB Entry DOI: 10.7270/Q28C9VHC |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| 11.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 181-91 (1997)
BindingDB Entry DOI: 10.7270/Q29K48SD |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone |
Bioorg Med Chem Lett 8: 2033-8 (1999)
BindingDB Entry DOI: 10.7270/Q2222V8M |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt
Curated by ChEMBL
| Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone |
Bioorg Med Chem Lett 8: 2033-8 (1999)
BindingDB Entry DOI: 10.7270/Q2222V8M |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Scuola di Scienze del Farmaco e dei Prodotti della Salute , Università di Camerino , Via S. Agostino 1 , 62032 Camerino , Italy.
Curated by ChEMBL
| Assay Description
Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced mVenus-... |
J Med Chem 61: 3712-3725 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00265
BindingDB Entry DOI: 10.7270/Q20K2C2P |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Scuola di Scienze del Farmaco e dei Prodotti della Salute , Università di Camerino , Via S. Agostino 1 , 62032 Camerino , Italy.
Curated by ChEMBL
| Assay Description
Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced RLuc8-f... |
J Med Chem 61: 3712-3725 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00265
BindingDB Entry DOI: 10.7270/Q20K2C2P |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00840
BindingDB Entry DOI: 10.7270/Q2ST7TTC |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00840
BindingDB Entry DOI: 10.7270/Q2ST7TTC |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00840
BindingDB Entry DOI: 10.7270/Q2ST7TTC |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | n/a | n/a | 2.23E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Effective concentration against human Dopamine receptor D4 |
J Med Chem 47: 2348-55 (2004)
Article DOI: 10.1021/jm0305669
BindingDB Entry DOI: 10.7270/Q2M61M03 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | PDB
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| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description
Tested for the effective concentration against CHO 10001 cells in human D4.2 receptor established in mitogenesis assay |
Bioorg Med Chem Lett 12: 633-6 (2002)
BindingDB Entry DOI: 10.7270/Q2JM2B5X |
More data for this
Ligand-Target Pair | |
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