Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-C (Homo sapiens (Human)) | BDBM50529873 (CHEMBL4552616) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from recombinant full-length human N-terminal GST-fused CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) expre... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529873 (CHEMBL4552616) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from recombinant full-length human N-terminal GST-fused CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) expre... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50529873 (CHEMBL4552616) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50529873 (CHEMBL4552616) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM50459995 (CHEMBL4225966 | US11471446, Compound DBA-10) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of CDK8 (unknown origin) | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM50459995 (CHEMBL4225966 | US11471446, Compound DBA-10) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of CDK8 (unknown origin) | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50459995 (CHEMBL4225966 | US11471446, Compound DBA-10) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of CDK19 (unknown origin) | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50459995 (CHEMBL4225966 | US11471446, Compound DBA-10) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of CDK19 (unknown origin) | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529874 (CHEMBL4584762) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529874 (CHEMBL4584762) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529875 (CHEMBL4580000) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from recombinant full-length human N-terminal GST-fused CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) expre... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529875 (CHEMBL4580000) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from recombinant full-length human N-terminal GST-fused CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) expre... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529877 (CHEMBL4451211) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529877 (CHEMBL4451211) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50529875 (CHEMBL4580000) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50529875 (CHEMBL4580000) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529876 (CHEMBL4472053) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 386 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50529876 (CHEMBL4472053) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 386 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length GST/His-fused CDK8/CycC expressed in Sf9 insect cells using RBER-IRStide as substrate after 1 hr in prese... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM62810 (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human His-tagged CDK8/cyclinC expressed in baculovirus expression system by Lantha screen assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM62810 (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant full-length human His-tagged CDK8/cyclinC expressed in baculovirus expression system by Lantha screen assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM62810 (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydr...) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human GST/His-tagged CDK11 (1 to 502 residues)/cyclinC (1 to 283 residues) catalytic domain expressed in insect cells by La... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM62810 (2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydr...) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of recombinant human GST/His-tagged CDK11 (1 to 502 residues)/cyclinC (1 to 283 residues) catalytic domain expressed in insect cells by La... | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM31340 (2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human ERRB2 (K646 to V1225 residues) expressed in mammalian expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human PKACalpha (G10 to F351 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human ROCK1 (M1 to R415 residues) expressed in mammalian expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK11 (M1 to N360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM31340 (2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK11 (M1 to N360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human ROCK1 (M1 to R415 residues) expressed in mammalian expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of CDK8/CyclinC (unknown origin) | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM31340 (2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human ERRB2 (K646 to V1225 residues) expressed in mammalian expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM31340 (2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Inhibition of CDK8/CyclinC (unknown origin) | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human ROCK2 (M1 to T431 residues) expressed in mammalian expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM50459994 (CHEMBL4226806 | US11471446, Compound DBA-8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human ROCK2 (M1 to T431 residues) expressed in mammalian expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50459994 (CHEMBL4226806 | US11471446, Compound DBA-8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK11 (M1 to N360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50459994 (CHEMBL4226806 | US11471446, Compound DBA-8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK11 (M1 to N360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM50459994 (CHEMBL4226806 | US11471446, Compound DBA-8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human PKACalpha (G10 to F351 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 8 (Homo sapiens (Human)) | BDBM50248631 (CHEMBL4080906) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
Shaoxing University Curated by ChEMBL | Assay Description Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay | Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076 BindingDB Entry DOI: 10.7270/Q25142PT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |