Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for entry = 50013163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50563323 (CHEMBL4791586) Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSKbeta H350L mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of [...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 | US11471446, Compound DBA-11) Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI InChI=1S/C23H24ClN5O/c1-28-15-18(12-27-28)16-2-4-17(5-3-16)19-13-25-14-20(24)21(19)29-10-7-23(8-11-29)6-9-26-22(23)30/h2-5,12-15H,6-11H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSKalpha S449A mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of ...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563321 (CHEMBL4744174) Show SMILES Clc1cncc(-c2c[nH]c3ncccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563310 (CHEMBL4790136) Show SMILES Clc1cncc(-c2cccc3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563313 (CHEMBL4778713) Show SMILES Clc1cncc(-c2cccc3c4ccccc4oc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSKbeta H350L mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of [...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563303 (CHEMBL4788598) Show SMILES Clc1cncc(-c2cccc3[nH]ccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563325 (CHEMBL4743413) Show SMILES Clc1cncc(-c2csc3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563311 (CHEMBL4757811) Show SMILES Cc1ccc(-c2cncc(Cl)c2N2CCC3(CCNC3=O)CC2)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563306 (CHEMBL4798011) Show SMILES Clc1cncc(-c2cccc3ncccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563314 (CHEMBL4783542) Show SMILES Clc1cncc(-c2cccc3c4ccccc4sc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563312 (CHEMBL4780807) Show SMILES COc1ccc(-c2cncc(Cl)c2N2CCC3(CCNC3=O)CC2)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563296 (CHEMBL4745572) Show SMILES Clc1cncc(-c2cnn(c2)-c2ccccc2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM50563323 (CHEMBL4791586) Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSKalpha S449A mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of ...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563323 (CHEMBL4791586) Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563320 (CHEMBL4778461) Show SMILES Clc1cncc(-c2cn(c3ncccc23)S(=O)(=O)c2ccccc2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563307 (CHEMBL4743572) Show SMILES Clc1cncc(-c2cccc3cnccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563302 (CHEMBL4800651) Show SMILES Cn1cc2c(cccc2n1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563319 (CHEMBL4800101) Show SMILES Clc1cncc(-c2c[nH]c3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563317 (CHEMBL4758431) Show SMILES Clc1cncc(-c2cn(Cc3ccccc3)c3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 | US11471446, Compound DBA-11) Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI InChI=1S/C23H24ClN5O/c1-28-15-18(12-27-28)16-2-4-17(5-3-16)19-13-25-14-20(24)21(19)29-10-7-23(8-11-29)6-9-26-22(23)30/h2-5,12-15H,6-11H2,1H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human full length PKCtheta using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintillation counting...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563304 (CHEMBL4749963) Show SMILES Clc1cncc(-c2cncc3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563316 (CHEMBL4797631) Show SMILES Cn1c(cc2ccccc12)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human full length PKCtheta using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintillation counting...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563309 (CHEMBL4740495) Show SMILES Clc1cncc(-c2cccc3cccnc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563298 (CHEMBL4763695) Show SMILES Clc1cncc(-c2cnn(c2)N2CCOCC2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50563323 (CHEMBL4791586) Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human full length PKCtheta using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintillation counting...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563305 (CHEMBL4780661) Show SMILES Clc1cncc(-c2ccnc3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563315 (CHEMBL4752645) Show SMILES Clc1cncc(-c2cc3ccccc3[nH]2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 | US11471446, Compound DBA-11) Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI InChI=1S/C23H24ClN5O/c1-28-15-18(12-27-28)16-2-4-17(5-3-16)19-13-25-14-20(24)21(19)29-10-7-23(8-11-29)6-9-26-22(23)30/h2-5,12-15H,6-11H2,1H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	231	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSKalpha S449A mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of ...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50073190 (CHEMBL3408213 | US11471446, Compound DBA-11) Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI InChI=1S/C23H24ClN5O/c1-28-15-18(12-27-28)16-2-4-17(5-3-16)19-13-25-14-20(24)21(19)29-10-7-23(8-11-29)6-9-26-22(23)30/h2-5,12-15H,6-11H2,1H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	345	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSKbeta H350L mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of [...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563297 (CHEMBL4788142) Show SMILES Clc1cncc(-c2cnn(Cc3ccccc3)c2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	346	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563301 (CHEMBL4745917) Show SMILES Cn1ncc2c(cccc12)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	458	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563318 (CHEMBL4781067) Show SMILES Clc1cncc(-c2cn(c3ccccc23)S(=O)(=O)c2ccccc2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	645	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563300 (CHEMBL4744071) Show SMILES Cn1ncc2cc(Nc3cncc(Cl)c3N3CCC4(CCNC4=O)CC3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563299 (CHEMBL4750543) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1cc(cn1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563294 (CHEMBL4781772) Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1-n1ccc(c1)C(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563324 (CHEMBL4790113) Show SMILES Clc1cncc(-c2coc3ccccc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK9/Cyclin T1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK1/cyclin-B (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563295 (CHEMBL4750545) Show SMILES CNC(=O)c1ccn(c1)-c1c(Cl)cncc1-c1ccc(cc1)-c1cnn(C)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563308 (CHEMBL4754432) Show SMILES Clc1cncc(-c2cccc3ccncc23)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50563293 (CHEMBL4785712) Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1-n1ccc(c1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50563323 (CHEMBL4791586) Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam 1-hydroxylation as substrate by LC-MS/MS analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam 1-hydroxylation as substrate by LC-MS/MS analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG expressed in CHO cells				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50563323 (CHEMBL4791586) Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG expressed in CHO cells				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50563322 (CHEMBL4777349) Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C19 in human liver microsomes using tolbutamide 4-hydroxylation as substrate by LC-MS/MS analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113248 BindingDB Entry DOI: 10.7270/Q2930XW8
					More data for this Ligand-Target Pair

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