Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with all data for entry = 50013987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571491 (CHEMBL4868092) Show SMILES Cc1c(NC(=O)CCNC2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 ITD mutant (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 ITD mutant (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571484 (CHEMBL4851401) Show SMILES Cc1c(NC(=O)CCN2CCCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 D835Y mutant (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571480 (CHEMBL4862765) Show SMILES Cc1c(NC(=O)CN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571487 (CHEMBL4877838) Show SMILES CN(C)CCC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571489 (CHEMBL4860305) Show SMILES CCCNCCC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571490 (CHEMBL4853071) Show SMILES Cc1c(NC(=O)CCNC(C)(C)C)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 D835Y mutant (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571483 (CHEMBL4866775) Show SMILES CN(C)CC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571486 (CHEMBL4864382) Show SMILES CCN(CC)CCC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571479 (CHEMBL4846119) Show SMILES Cc1c(NC(=O)C2CCCCN2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571488 (CHEMBL4862737) Show SMILES CCNCCC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571478 (CHEMBL4861526) Show SMILES Cc1c(NC(=O)[C@@H]2CCCN2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571482 (CHEMBL4868929) Show SMILES CN1CCN(CC(=O)Nc2c[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c2C)CC1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571481 (CHEMBL4865208) Show SMILES Cc1c(NC(=O)CC2CCCN2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-KIT (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571485 (CHEMBL4857231) Show SMILES CN1CCN(CCC(=O)Nc2c[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c2C)CC1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFRbeta (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 ITD mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs by CCK8 assa...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 ITD/D835V double mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFRalpha (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TEL-FLT3 D835V mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs by CCK...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 ITD/D835Y double mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TEL-FLT3 D835Y mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs by CCK...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFRbeta (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 ITD/F691L double mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TEL-FLT3 D835H mutant (unknown origin) expressed in mouse BaF3 cells assessed as antiproliferative activity incubated for 72 hrs by CCK...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFRalpha (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CSF1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR1 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR1 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	716	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CSF1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50571477 (CHEMBL4869059) Show SMILES Cc1c(NC(=O)CCN2CCCC2)c[nH]c1\C=C1/C(=O)Nc2ccc(F)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-KIT (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02247 BindingDB Entry DOI: 10.7270/Q29G5RKV
					More data for this Ligand-Target Pair