Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50017923 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein ENL
(Homo sapiens) | BDBM50459745
(CHEMBL4210431)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N(C)C |r| Show InChI InChI=1S/C40H70N8O9/c1-12-25(8)33(40(57)48-18-14-15-30(48)35(52)42-27(19-22(2)3)38(55)46(10)11)45-34(51)29(21-49)43-37(54)32(24(6)7)44-36(53)31-16-13-17-47(31)39(56)28(20-23(4)5)41-26(9)50/h22-25,27-33,49H,12-21H2,1-11H3,(H,41,50)(H,42,52)(H,43,54)(H,44,53)(H,45,51)/t25-,27-,28-,29-,30-,31-,32-,33-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606137
(CHEMBL5187921)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N(C)C |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606139
(CHEMBL5198951)Show SMILES CNC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CCC(C)C)C(C)C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606141
(CHEMBL5187149)Show SMILES CC(C)CCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606142
(CHEMBL5197715)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](Cc1ccccc1)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606140
(CHEMBL5184570)Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)c1ccccc1)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606146
(CHEMBL5206253)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606144
(CHEMBL5199592)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](CC(C)C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606147
(CHEMBL5203898)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N1CCC[C@H]1c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606143
(CHEMBL5208460)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCC1)NC(=O)[C@H](CN)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50459730
(CHEMBL4211714)Show SMILES CC(C)CCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N1CCC[C@H]1c1nc(cn1CC1CCCCC1)-c1ccccc1 |r| Show InChI InChI=1S/C47H72N8O5/c1-31(2)23-24-41(56)54-25-14-22-40(54)45(58)52-42(32(3)4)46(59)51-37(28-48)44(57)50-36(27-33-15-11-12-16-33)47(60)55-26-13-21-39(55)43-49-38(35-19-9-6-10-20-35)30-53(43)29-34-17-7-5-8-18-34/h6,9-10,19-20,30-34,36-37,39-40,42H,5,7-8,11-18,21-29,48H2,1-4H3,(H,50,57)(H,51,59)(H,52,58)/t36-,37-,39-,40-,42-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606145
(CHEMBL5190103)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C(C)C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606138
(CHEMBL5207031)Show SMILES CNC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)c1ccccc1)C(C)C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606139
(CHEMBL5198951)Show SMILES CNC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CCC(C)C)C(C)C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606141
(CHEMBL5187149)Show SMILES CC(C)CCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 112 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606142
(CHEMBL5197715)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](Cc1ccccc1)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 157 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50606137
(CHEMBL5187921)Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N(C)C |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein AF-9
(Homo sapiens) | BDBM50459745
(CHEMBL4210431)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N(C)C |r| Show InChI InChI=1S/C40H70N8O9/c1-12-25(8)33(40(57)48-18-14-15-30(48)35(52)42-27(19-22(2)3)38(55)46(10)11)45-34(51)29(21-49)43-37(54)32(24(6)7)44-36(53)31-16-13-17-47(31)39(56)28(20-23(4)5)41-26(9)50/h22-25,27-33,49H,12-21H2,1-11H3,(H,41,50)(H,42,52)(H,43,54)(H,44,53)(H,45,51)/t25-,27-,28-,29-,30-,31-,32-,33-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606146
(CHEMBL5206253)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 184 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606144
(CHEMBL5199592)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](CC(C)C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 204 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606140
(CHEMBL5184570)Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)c1ccccc1)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 209 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606138
(CHEMBL5207031)Show SMILES CNC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)c1ccccc1)C(C)C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 231 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606147
(CHEMBL5203898)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N1CCC[C@H]1c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 232 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50459730
(CHEMBL4211714)Show SMILES CC(C)CCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N1CCC[C@H]1c1nc(cn1CC1CCCCC1)-c1ccccc1 |r| Show InChI InChI=1S/C47H72N8O5/c1-31(2)23-24-41(56)54-25-14-22-40(54)45(58)52-42(32(3)4)46(59)51-37(28-48)44(57)50-36(27-33-15-11-12-16-33)47(60)55-26-13-21-39(55)43-49-38(35-19-9-6-10-20-35)30-53(43)29-34-17-7-5-8-18-34/h6,9-10,19-20,30-34,36-37,39-40,42H,5,7-8,11-18,21-29,48H2,1-4H3,(H,50,57)(H,51,59)(H,52,58)/t36-,37-,39-,40-,42-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606145
(CHEMBL5190103)Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CN)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](C(C)C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |
Protein ENL
(Homo sapiens) | BDBM50606143
(CHEMBL5208460)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCC1)NC(=O)[C@H](CN)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)c1nc2cccc(-c3ccccc3)c2[nH]1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 254 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00083 BindingDB Entry DOI: 10.7270/Q2VT1X6W |
More data for this Ligand-Target Pair | |