Found 10 hits Enz. Inhib. hit(s) with all data for entry = 50018025 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50431015
(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12 Show InChI InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.11E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607005
(CHEMBL5219927)Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ncc(C(=O)NCC(O)=O)c(O)n1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.27E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607006
(CHEMBL5218506)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)c2ccc(Cl)cc2)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.54E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607007
(CHEMBL5219872)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.91E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607013
(CHEMBL5219134)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)Cc2ccccc2)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607009
(CHEMBL5218673)Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ncc(C(=O)NCC(O)=O)c(O)n1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607010
(CHEMBL5218720)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)c2cccc(Cl)c2)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607011
(CHEMBL5219277)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607012
(CHEMBL5220549)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.46E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1
(Homo sapiens (Human)) | BDBM50607008
(CHEMBL5218607)Show SMILES OC(=O)CNC(=O)c1cnc(NS(=O)(=O)c2ccc(Br)cc2)nc1O | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.97E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.129007
BindingDB Entry DOI: 10.7270/Q2CJ8JKT |
More data for this
Ligand-Target Pair | |
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