Compile Data Set for Download or QSAR

Found 348 hits Enz. Inhib. hit(s) with all data for entry = 2842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382217 (US10273244, Example 64 | US10584135, Example 64) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(F)cc2)nnc1C1CCCCC1 |r| Show InChI InChI=1S/C24H34FN5S/c1-28-23(18-6-3-2-4-7-18)26-27-24(28)31-15-5-13-29-16-19-12-14-30(22(19)17-29)21-10-8-20(25)9-11-21/h8-11,18-19,22H,2-7,12-17H2,1H3/t19-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154890 (CHEMBL3774425 | US10273244, Example 113 | US105841...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2cccc(c2)C(F)(F)F)nnc1-c1cnccn1 Show InChI InChI=1S/C23H26F3N7S/c1-31-21(19-13-27-7-8-28-19)29-30-22(31)34-11-3-9-32-14-16-6-10-33(20(16)15-32)18-5-2-4-17(12-18)23(24,25)26/h2,4-5,7-8,12-13,16,20H,3,6,9-11,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154897 (CHEMBL3774463 | US10273244, Example 56 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCCCC1 Show InChI InChI=1S/C25H34F3N5S/c1-31-23(18-6-3-2-4-7-18)29-30-24(31)34-15-5-13-32-16-19-12-14-33(22(19)17-32)21-10-8-20(9-11-21)25(26,27)28/h8-11,18-19,22H,2-7,12-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154878 (CHEMBL3774895 | US10273244, Example 114 | US105841...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2cccc(OC(F)(F)F)c2)nnc1-c1cnccn1 Show InChI InChI=1S/C23H26F3N7OS/c1-31-21(19-13-27-7-8-28-19)29-30-22(31)35-11-3-9-32-14-16-6-10-33(20(16)15-32)17-4-2-5-18(12-17)34-23(24,25)26/h2,4-5,7-8,12-13,16,20H,3,6,9-11,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382214 (US10273244, Example 59 | US10584135, Example 59) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCCCC1 |r| Show InChI InChI=1S/C25H34F3N5S/c1-31-23(18-6-3-2-4-7-18)29-30-24(31)34-15-5-13-32-16-19-12-14-33(22(19)17-32)21-10-8-20(9-11-21)25(26,27)28/h8-11,18-19,22H,2-7,12-17H2,1H3/t19-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382215 (US10273244, Example 60 | US10584135, Example 60) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCCCC1 |r| Show InChI InChI=1S/C25H34F3N5S/c1-31-23(18-6-3-2-4-7-18)29-30-24(31)34-15-5-13-32-16-19-12-14-33(22(19)17-32)21-10-8-20(9-11-21)25(26,27)28/h8-11,18-19,22H,2-7,12-17H2,1H3/t19-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154898 (CHEMBL3774431 | US10273244, Example 61 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(F)cc2)nnc1C1CCCCC1 Show InChI InChI=1S/C24H34FN5S/c1-28-23(18-6-3-2-4-7-18)26-27-24(28)31-15-5-13-29-16-19-12-14-30(22(19)17-29)21-10-8-20(25)9-11-21/h8-11,18-19,22H,2-7,12-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154894 (CHEMBL3775338 | US10273244, Example 28 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2cc(Cl)cc(Cl)c2)n1C Show InChI InChI=1S/C22H26Cl2N6OS/c1-14-20(31-13-25-14)21-26-27-22(28(21)2)32-7-3-5-29-11-15-4-6-30(19(15)12-29)18-9-16(23)8-17(24)10-18/h8-10,13,15,19H,3-7,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.417	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382318 (US10273244, Example 199 | US10584135, Example 199) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(F)cc2)nnc1-c1ccc(nc1)C(N)=O |r| Show InChI InChI=1S/C24H28FN7OS/c1-30-23(16-3-8-20(22(26)33)27-13-16)28-29-24(30)34-12-2-10-31-14-17-9-11-32(21(17)15-31)19-6-4-18(25)5-7-19/h3-8,13,17,21H,2,9-12,14-15H2,1H3,(H2,26,33)/t17-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.513	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382317 (US10273244, Example 198 | US10584135, Example 198) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(F)cc2)nnc1-c1ccc(nc1)C(N)=O Show InChI InChI=1S/C24H28FN7OS/c1-30-23(16-3-8-20(22(26)33)27-13-16)28-29-24(30)34-12-2-10-31-14-17-9-11-32(21(17)15-31)19-6-4-18(25)5-7-19/h3-8,13,17,21H,2,9-12,14-15H2,1H3,(H2,26,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.525	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382315 (US10273244, Example 196 | US10584135, Example 196) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccc(nc1)C(N)=O |r| Show InChI InChI=1S/C25H28F3N7OS/c1-33-23(16-3-8-20(22(29)36)30-13-16)31-32-24(33)37-12-2-10-34-14-17-9-11-35(21(17)15-34)19-6-4-18(5-7-19)25(26,27)28/h3-8,13,17,21H,2,9-12,14-15H2,1H3,(H2,29,36)/t17-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382178 (US10273244, Example 10 | US10584135, Example 10) Show SMILES Cc1ncoc1-c1nnc(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2cccc(c2)C#N)n1C |r| Show InChI InChI=1S/C23H27N7OS/c1-16-21(31-15-25-16)22-26-27-23(28(22)2)32-10-4-8-29-13-18-7-9-30(20(18)14-29)19-6-3-5-17(11-19)12-24/h3,5-6,11,15,18,20H,4,7-10,13-14H2,1-2H3/t18-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.646	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382324 (US10273244, Example 205 | US10584135, Example 205) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2c(F)cc(F)cc2F)nnc1-c1ccc(nc1)C(N)=O |r| Show InChI InChI=1S/C24H26F3N7OS/c1-32-23(14-3-4-19(22(28)35)29-11-14)30-31-24(32)36-8-2-6-33-12-15-5-7-34(20(15)13-33)21-17(26)9-16(25)10-18(21)27/h3-4,9-11,15,20H,2,5-8,12-13H2,1H3,(H2,28,35)/t15-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.646	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382314 (US10273244, Example 195 | US10584135, Example 195) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccc(nc1)C(N)=O Show InChI InChI=1S/C25H28F3N7OS/c1-33-23(16-3-8-20(22(29)36)30-13-16)31-32-24(33)37-12-2-10-34-14-17-9-11-35(21(17)15-34)19-6-4-18(5-7-19)25(26,27)28/h3-8,13,17,21H,2,9-12,14-15H2,1H3,(H2,29,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.776	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382218 (US10273244, Example 65 | US10584135, Example 65) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(F)cc2)nnc1C1CCCCC1 |r| Show InChI InChI=1S/C24H34FN5S/c1-28-23(18-6-3-2-4-7-18)26-27-24(28)31-15-5-13-29-16-19-12-14-30(22(19)17-29)21-10-8-20(25)9-11-21/h8-11,18-19,22H,2-7,12-17H2,1H3/t19-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154877 (CHEMBL3774621 | US10273244, Example 96 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccccc2OC(F)(F)F)nnc1-c1cnccn1 Show InChI InChI=1S/C23H26F3N7OS/c1-31-21(17-13-27-8-9-28-17)29-30-22(31)35-12-4-10-32-14-16-7-11-33(19(16)15-32)18-5-2-3-6-20(18)34-23(24,25)26/h2-3,5-6,8-9,13,16,19H,4,7,10-12,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382301 (US10273244, Example 178 | US10584135, Example 178) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2cccc(c2)C(F)(F)F)nnc1-c1ccc(=O)[nH]c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382188 (US10273244, Example 23 | US10584135, Example 23) Show SMILES Cc1ncoc1-c1nnc(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(F)cc2)n1C |r| Show InChI InChI=1S/C22H27FN6OS/c1-15-20(30-14-24-15)21-25-26-22(27(21)2)31-11-3-9-28-12-16-8-10-29(19(16)13-28)18-6-4-17(23)5-7-18/h4-7,14,16,19H,3,8-13H2,1-2H3/t16-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.871	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382203 (US10273244, Example 44 | US10584135, Example 44) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(F)cc2)nnc1C1CCOCC1 |r| Show InChI InChI=1S/C23H32FN5OS/c1-27-22(17-8-12-30-13-9-17)25-26-23(27)31-14-2-10-28-15-18-7-11-29(21(18)16-28)20-5-3-19(24)4-6-20/h3-6,17-18,21H,2,7-16H2,1H3/t18-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382316 (US10273244, Example 197 | US10584135, Example 197) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccc(nc1)C(N)=O |r| Show InChI InChI=1S/C25H28F3N7OS/c1-33-23(16-3-8-20(22(29)36)30-13-16)31-32-24(33)37-12-2-10-34-14-17-9-11-35(21(17)15-34)19-6-4-18(5-7-19)25(26,27)28/h3-8,13,17,21H,2,9-12,14-15H2,1H3,(H2,29,36)/t17-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382323 (US10273244, Example 204 | US10584135, Example 204) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2c(F)cc(F)cc2F)nnc1-c1ccc(nc1)C(N)=O Show InChI InChI=1S/C24H26F3N7OS/c1-32-23(14-3-4-19(22(28)35)29-11-14)30-31-24(32)36-8-2-6-33-12-15-5-7-34(20(15)13-33)21-17(26)9-16(25)10-18(21)27/h3-4,9-11,15,20H,2,5-8,12-13H2,1H3,(H2,28,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154891 (CHEMBL3775872 | US10273244, Example 25 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2OC(F)(F)F)n1C Show InChI InChI=1S/C23H27F3N6O2S/c1-15-20(33-14-27-15)21-28-29-22(30(21)2)35-11-5-9-31-12-16-8-10-32(18(16)13-31)17-6-3-4-7-19(17)34-23(24,25)26/h3-4,6-7,14,16,18H,5,8-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154869 (CHEMBL3774519 | US10273244, Example 133 | US105841...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2c(F)cc(F)cc2F)nnc1-c1cnccn1 Show InChI InChI=1S/C22H24F3N7S/c1-30-21(18-11-26-4-5-27-18)28-29-22(30)33-8-2-6-31-12-14-3-7-32(19(14)13-31)20-16(24)9-15(23)10-17(20)25/h4-5,9-11,14,19H,2-3,6-8,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382335 (US10273244, Example 221) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCC(O)CC1 |r,w:27.31,31.35,wD:9.8,13.12,(3.57,-.39,;3.97,1.1,;3.07,2.35,;1.58,1.95,;.49,3.04,;-1,2.64,;-2.09,3.73,;-3.57,3.33,;-4.48,4.57,;-5.94,4.1,;-7.41,4.57,;-8.31,3.33,;-7.41,2.08,;-5.94,2.56,;-4.48,2.08,;-7.81,.6,;-9.29,.2,;-9.69,-1.29,;-8.62,-2.43,;-7.12,-1.98,;-6.72,-.49,;-9.02,-3.92,;-9.42,-5.41,;-10.5,-3.52,;-7.53,-4.32,;3.97,3.59,;5.44,3.12,;5.44,1.58,;6.77,.81,;6.77,-.73,;8.1,-1.5,;9.44,-.73,;10.77,-1.5,;9.44,.81,;8.1,1.58,)| Show InChI InChI=1S/C25H34F3N5OS/c1-31-23(17-3-9-21(34)10-4-17)29-30-24(31)35-14-2-12-32-15-18-11-13-33(22(18)16-32)20-7-5-19(6-8-20)25(26,27)28/h5-8,17-18,21-22,34H,2-4,9-16H2,1H3/t17?,18-,21?,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382186 (US10273244, Example 21 | US10584135, Example 21) Show SMILES Cc1ncoc1-c1nnc(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2F)C(F)(F)F)n1C |r| Show InChI InChI=1S/C23H26F4N6OS/c1-14-20(34-13-28-14)21-29-30-22(31(21)2)35-9-3-7-32-11-15-6-8-33(19(15)12-32)18-5-4-16(10-17(18)24)23(25,26)27/h4-5,10,13,15,19H,3,6-9,11-12H2,1-2H3/t15-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382183 (US10273244, Example 16 | US10584135, Example 16) Show SMILES Cc1ncoc1-c1nnc(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccccc2)n1C |r| Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3/t17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382333 (US10273244, Example 218) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCC(O)CC1 |w:27.31,31.35,(3.57,.14,;3.97,1.63,;3.07,2.88,;1.58,2.48,;.49,3.57,;-1,3.17,;-2.09,4.26,;-3.57,3.86,;-4.48,5.11,;-5.94,4.63,;-7.41,5.11,;-8.31,3.86,;-7.41,2.61,;-5.94,3.09,;-4.48,2.61,;-7.81,1.13,;-9.29,.73,;-9.69,-.76,;-8.64,-1.99,;-7.12,-1.45,;-6.72,.04,;-9.04,-3.47,;-9.44,-4.96,;-10.53,-3.08,;-7.55,-3.87,;3.97,4.12,;5.44,3.65,;5.44,2.11,;6.77,1.34,;6.77,-.2,;8.1,-.97,;9.44,-.2,;10.77,-.97,;9.44,1.34,;8.1,2.11,)| Show InChI InChI=1S/C25H34F3N5OS/c1-31-23(17-3-9-21(34)10-4-17)29-30-24(31)35-14-2-12-32-15-18-11-13-33(22(18)16-32)20-7-5-19(6-8-20)25(26,27)28/h5-8,17-18,21-22,34H,2-4,9-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382322 (US10273244, Example 203 | US10584135, Example 203) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2c(F)cccc2F)nnc1-c1ccc(nc1)C(N)=O |r| Show InChI InChI=1S/C24H27F2N7OS/c1-31-23(15-6-7-19(22(27)34)28-12-15)29-30-24(31)35-11-3-9-32-13-16-8-10-33(20(16)14-32)21-17(25)4-2-5-18(21)26/h2,4-7,12,16,20H,3,8-11,13-14H2,1H3,(H2,27,34)/t16-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154867 (CHEMBL3775810 | US10273244, Example 134 | US105841...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccncn1 Show InChI InChI=1S/C23H26F3N7S/c1-31-21(19-7-9-27-15-28-19)29-30-22(31)34-12-2-10-32-13-16-8-11-33(20(16)14-32)18-5-3-17(4-6-18)23(24,25)26/h3-7,9,15-16,20H,2,8,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154850 (CHEMBL3774588 | US10273244, Example 22 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccc(F)cc2)n1C Show InChI InChI=1S/C22H27FN6OS/c1-15-20(30-14-24-15)21-25-26-22(27(21)2)31-11-3-9-28-12-16-8-10-29(19(16)13-28)18-6-4-17(23)5-7-18/h4-7,14,16,19H,3,8-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382320 (US10273244, Example 201 | US10584135, Example 201) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2c(F)cccc2F)nnc1-c1ccc(nc1)C(N)=O Show InChI InChI=1S/C24H27F2N7OS/c1-31-23(15-6-7-19(22(27)34)28-12-15)29-30-24(31)35-11-3-9-32-13-16-8-10-33(20(16)14-32)21-17(25)4-2-5-18(21)26/h2,4-7,12,16,20H,3,8-11,13-14H2,1H3,(H2,27,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154895 (CHEMBL3775534 | US10273244, Example 7 | US10584135...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2cccc(c2)C#N)n1C Show InChI InChI=1S/C23H27N7OS/c1-16-21(31-15-25-16)22-26-27-23(28(22)2)32-10-4-8-29-13-18-7-9-30(20(18)14-29)19-6-3-5-17(11-19)12-24/h3,5-6,11,15,18,20H,4,7-10,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154851 (CHEMBL3774683 | US10273244, Example 89 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1cnccn1 Show InChI InChI=1S/C23H26F3N7S/c1-31-21(19-13-27-8-9-28-19)29-30-22(31)34-12-2-10-32-14-16-7-11-33(20(16)15-32)18-5-3-17(4-6-18)23(24,25)26/h3-6,8-9,13,16,20H,2,7,10-12,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382270 (US10273244, Example 139 | US10584135, Example 139) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(F)cc2)nnc1-c1ccncn1 Show InChI InChI=1S/C22H26FN7S/c1-28-21(19-7-9-24-15-25-19)26-27-22(28)31-12-2-10-29-13-16-8-11-30(20(16)14-29)18-5-3-17(23)4-6-18/h3-7,9,15-16,20H,2,8,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154896 (CHEMBL3774462 | US10273244, Example 51 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCCC1 Show InChI InChI=1S/C24H32F3N5S/c1-30-22(17-5-2-3-6-17)28-29-23(30)33-14-4-12-31-15-18-11-13-32(21(18)16-31)20-9-7-19(8-10-20)24(25,26)27/h7-10,17-18,21H,2-6,11-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382269 (US10273244, Example 138 | US10584135, Example 138) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccncn1 |r| Show InChI InChI=1S/C23H26F3N7S/c1-31-21(19-7-9-27-15-28-19)29-30-22(31)34-12-2-10-32-13-16-8-11-33(20(16)14-32)18-5-3-17(4-6-18)23(24,25)26/h3-7,9,15-16,20H,2,8,10-14H2,1H3/t16-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382307 (US10273244, Example 188 | US10584135, Example 188) Show SMILES Cn1nccc1-c1nnc(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)n1C |r| Show InChI InChI=1S/C23H28F3N7S/c1-30-21(19-8-10-27-31(19)2)28-29-22(30)34-13-5-11-32-14-16-9-12-33(20(16)15-32)18-7-4-3-6-17(18)23(24,25)26/h3-4,6-8,10,16,20H,5,9,11-15H2,1-2H3/t16-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154902 (CHEMBL3774540 | US10273244, Example 2 | US10584135...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)n1C Show InChI InChI=1S/C23H27F3N6OS/c1-15-20(33-14-27-15)21-28-29-22(30(21)2)34-11-3-9-31-12-16-8-10-32(19(16)13-31)18-6-4-17(5-7-18)23(24,25)26/h4-7,14,16,19H,3,8-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154859 (CHEMBL3775554 | US10273244, Example 160 | US105841...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccccn1 Show InChI InChI=1S/C24H27F3N6S/c1-31-22(20-5-2-3-11-28-20)29-30-23(31)34-14-4-12-32-15-17-10-13-33(21(17)16-32)19-8-6-18(7-9-19)24(25,26)27/h2-3,5-9,11,17,21H,4,10,12-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382283 (US10273244, Example 158 | US10584135, Example 158) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)nnc1-c1ccncc1 |r| Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-7-10-28-11-8-17)29-30-23(31)34-14-4-12-32-15-18-9-13-33(21(18)16-32)20-6-3-2-5-19(20)24(25,26)27/h2-3,5-8,10-11,18,21H,4,9,12-16H2,1H3/t18-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382319 (US10273244, Example 200 | US10584135, Example 200) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(F)cc2)nnc1-c1ccc(nc1)C(N)=O |r| Show InChI InChI=1S/C24H28FN7OS/c1-30-23(16-3-8-20(22(26)33)27-13-16)28-29-24(30)34-12-2-10-31-14-17-9-11-32(21(17)15-31)19-6-4-18(25)5-7-19/h3-8,13,17,21H,2,9-12,14-15H2,1H3,(H2,26,33)/t17-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154860 (CHEMBL3774490 | US10273244, Example 153 | US105841...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1ccncc1 Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-7-10-28-11-8-17)29-30-23(31)34-14-2-12-32-15-18-9-13-33(21(18)16-32)20-5-3-19(4-6-20)24(25,26)27/h3-8,10-11,18,21H,2,9,12-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382236 (US10273244, Example 93 | US10584135, Example 93) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1cnccn1 |r| Show InChI InChI=1S/C23H26F3N7S/c1-31-21(19-13-27-8-9-28-19)29-30-22(31)34-12-2-10-32-14-16-7-11-33(20(16)15-32)18-5-3-17(4-6-18)23(24,25)26/h3-6,8-9,13,16,20H,2,7,10-12,14-15H2,1H3/t16-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382230 (US10273244, Example 85 | US10584135, Example 85) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1N1CCOCC1 |r| Show InChI InChI=1S/C23H31F3N6OS/c1-29-21(31-10-12-33-13-11-31)27-28-22(29)34-14-2-8-30-15-17-7-9-32(20(17)16-30)19-5-3-18(4-6-19)23(24,25)26/h3-6,17,20H,2,7-16H2,1H3/t17-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154843 (CHEMBL3775226 | US10273244, Example 17 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccc(cc2F)C(F)(F)F)n1C Show InChI InChI=1S/C23H26F4N6OS/c1-14-20(34-13-28-14)21-29-30-22(31(21)2)35-9-3-7-32-11-15-6-8-33(19(15)12-32)18-5-4-16(10-17(18)24)23(25,26)27/h4-5,10,13,15,19H,3,6-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	2.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154875 (CHEMBL3775667 | US10273244, Example 94 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2cccc(c2)C#N)nnc1-c1cnccn1 Show InChI InChI=1S/C23H26N8S/c1-29-22(20-14-25-7-8-26-20)27-28-23(29)32-11-3-9-30-15-18-6-10-31(21(18)16-30)19-5-2-4-17(12-19)13-24/h2,4-5,7-8,12,14,18,21H,3,6,9-11,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	2.09	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154888 (CHEMBL3774996 | US10273244, Example 95 | US1058413...) Show SMILES Cn1c(SCCCN2CC3CCN(C3C2)c2ccc(F)cc2)nnc1-c1cnccn1 Show InChI InChI=1S/C22H26FN7S/c1-28-21(19-13-24-8-9-25-19)26-27-22(28)31-12-2-10-29-14-16-7-11-30(20(16)15-29)18-5-3-17(23)4-6-18/h3-6,8-9,13,16,20H,2,7,10-12,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	2.09	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382334 (US10273244, Example 219) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1C1CCC(O)CC1 |r,w:27.31,31.35,wU:9.8,13.12,(3.57,7.24,;3.97,8.73,;3.07,9.97,;1.58,9.57,;.49,10.66,;-1,10.26,;-2.09,11.35,;-3.57,10.95,;-4.48,12.2,;-5.94,11.72,;-7.41,12.2,;-8.31,10.95,;-7.41,9.71,;-5.94,10.18,;-4.48,9.71,;-7.81,8.22,;-9.29,7.82,;-9.69,6.34,;-8.62,5.19,;-7.12,5.64,;-6.72,7.13,;-9.02,3.71,;-9.41,2.22,;-10.5,4.1,;-7.53,3.31,;3.97,11.22,;5.44,10.74,;5.44,9.2,;6.77,8.43,;6.77,6.89,;8.1,6.12,;9.44,6.89,;10.77,6.12,;9.44,8.43,;8.1,9.2,)| Show InChI InChI=1S/C25H34F3N5OS/c1-31-23(17-3-9-21(34)10-4-17)29-30-24(31)35-14-2-12-32-15-18-11-13-33(22(18)16-32)20-7-5-19(6-8-20)25(26,27)28/h5-8,17-18,21-22,34H,2-4,9-16H2,1H3/t17?,18-,21?,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382274 (US10273244, Example 145 | US10584135, Example 145) Show SMILES Cn1c(SCCCN2C[C@H]3CCN([C@H]3C2)c2ccc(cc2)C(F)(F)F)nnc1-c1cccnc1 |r| Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-4-2-10-28-14-17)29-30-23(31)34-13-3-11-32-15-18-9-12-33(21(18)16-32)20-7-5-19(6-8-20)24(25,26)27/h2,4-8,10,14,18,21H,3,9,11-13,15-16H2,1H3/t18-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM382178 (US10273244, Example 10 | US10584135, Example 10) Show SMILES Cc1ncoc1-c1nnc(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2cccc(c2)C#N)n1C |r| Show InChI InChI=1S/C23H27N7OS/c1-16-21(31-15-25-16)22-26-27-23(28(22)2)32-10-4-8-29-13-18-7-9-30(20(18)14-29)19-6-3-5-17(11-19)12-24/h3,5-6,11,15,18,20H,4,7-10,13-14H2,1-2H3/t18-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description Functional Calcium Assay at hD2 recombinant receptor. CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to G&#...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair

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