Compile Data Set for Download or QSAR

Found 40 hits Enz. Inhib. hit(s) with all data for entry = 9122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443226 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C)ncn2)c1Cl Show InChI InChI=1S/C30H36Cl2N8O4/c1-7-26(41)36-21-14-19(40-12-10-18(11-13-40)38(2)3)8-9-20(21)35-24-16-25(34-17-33-24)39(4)30(42)37-29-27(31)22(43-5)15-23(44-6)28(29)32/h7-9,14-18H,1,10-13H2,2-6H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443223 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)CC1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-17-32(18-42)10-12-41(7-2)13-11-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443222 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C31H36Cl2N8O4/c1-5-26(42)38-21-14-19(41-13-10-31(17-41)8-11-34-12-9-31)6-7-20(21)37-24-16-25(36-18-35-24)40(2)30(43)39-29-27(32)22(44-3)15-23(45-4)28(29)33/h5-7,14-16,18,34H,1,8-13,17H2,2-4H3,(H,38,42)(H,39,43)(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443225 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CCN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)C1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-13-11-32(18-42)10-12-41(7-2)17-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443224 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCN(CC11CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C31H36Cl2N8O4/c1-6-26(42)37-21-14-19(40-12-13-41(7-2)31(17-40)10-11-31)8-9-20(21)36-24-16-25(35-18-34-24)39(3)30(43)38-29-27(32)22(44-4)15-23(45-5)28(29)33/h6,8-9,14-16,18H,1,7,10-13,17H2,2-5H3,(H,37,42)(H,38,43)(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443227 (N-(5-(4-Cyclopropylpiperazin-1-yl)-2-((6-(3-(2,6-d...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCN(CC3)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-26(41)36-21-14-19(40-12-10-39(11-13-40)18-6-7-18)8-9-20(21)35-24-16-25(34-17-33-24)38(2)30(42)37-29-27(31)22(43-3)15-23(44-4)28(29)32/h5,8-9,14-18H,1,6-7,10-13H2,2-4H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443228 (N-(5-(4-(Cyclopropyl(methyl)amino)piperidin-1-yl)-...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-28(43)38-23-15-21(42-13-11-20(12-14-42)40(2)19-7-8-19)9-10-22(23)37-26-17-27(36-18-35-26)41(3)32(44)39-31-29(33)24(45-4)16-25(46-5)30(31)34/h6,9-10,15-20H,1,7-8,11-14H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443221 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCNC4(CC4)C3)ncn2)c1Cl Show InChI InChI=1S/C29H32Cl2N8O4/c1-5-24(40)36-19-12-17(39-11-10-34-29(15-39)8-9-29)6-7-18(19)35-22-14-23(33-16-32-22)38(2)28(41)37-27-25(30)20(42-3)13-21(43-4)26(27)31/h5-7,12-14,16,34H,1,8-11,15H2,2-4H3,(H,36,40)(H,37,41)(H,32,33,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM443220 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-25(41)37-20-12-18(40-15-30(16-40)8-10-33-11-9-30)6-7-19(20)36-23-14-24(35-17-34-23)39(2)29(42)38-28-26(31)21(43-3)13-22(44-4)27(28)32/h5-7,12-14,17,33H,1,8-11,15-16H2,2-4H3,(H,37,41)(H,38,42)(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM249396 (US10537571, Compound 108 | US10562888, Compound 10...) Show SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443221 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCNC4(CC4)C3)ncn2)c1Cl Show InChI InChI=1S/C29H32Cl2N8O4/c1-5-24(40)36-19-12-17(39-11-10-34-29(15-39)8-9-29)6-7-18(19)35-22-14-23(33-16-32-22)38(2)28(41)37-27-25(30)20(42-3)13-21(43-4)26(27)31/h5-7,12-14,16,34H,1,8-11,15H2,2-4H3,(H,36,40)(H,37,41)(H,32,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443220 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-25(41)37-20-12-18(40-15-30(16-40)8-10-33-11-9-30)6-7-19(20)36-23-14-24(35-17-34-23)39(2)29(42)38-28-26(31)21(43-3)13-22(44-4)27(28)32/h5-7,12-14,17,33H,1,8-11,15-16H2,2-4H3,(H,37,41)(H,38,42)(H,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443223 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)CC1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-17-32(18-42)10-12-41(7-2)13-11-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443226 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C)ncn2)c1Cl Show InChI InChI=1S/C30H36Cl2N8O4/c1-7-26(41)36-21-14-19(40-12-10-18(11-13-40)38(2)3)8-9-20(21)35-24-16-25(34-17-33-24)39(4)30(42)37-29-27(31)22(43-5)15-23(44-6)28(29)32/h7-9,14-18H,1,10-13H2,2-6H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443221 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCNC4(CC4)C3)ncn2)c1Cl Show InChI InChI=1S/C29H32Cl2N8O4/c1-5-24(40)36-19-12-17(39-11-10-34-29(15-39)8-9-29)6-7-18(19)35-22-14-23(33-16-32-22)38(2)28(41)37-27-25(30)20(42-3)13-21(43-4)26(27)31/h5-7,12-14,16,34H,1,8-11,15H2,2-4H3,(H,36,40)(H,37,41)(H,32,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443221 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCNC4(CC4)C3)ncn2)c1Cl Show InChI InChI=1S/C29H32Cl2N8O4/c1-5-24(40)36-19-12-17(39-11-10-34-29(15-39)8-9-29)6-7-18(19)35-22-14-23(33-16-32-22)38(2)28(41)37-27-25(30)20(42-3)13-21(43-4)26(27)31/h5-7,12-14,16,34H,1,8-11,15H2,2-4H3,(H,36,40)(H,37,41)(H,32,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM249396 (US10537571, Compound 108 | US10562888, Compound 10...) Show SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443228 (N-(5-(4-(Cyclopropyl(methyl)amino)piperidin-1-yl)-...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-28(43)38-23-15-21(42-13-11-20(12-14-42)40(2)19-7-8-19)9-10-22(23)37-26-17-27(36-18-35-26)41(3)32(44)39-31-29(33)24(45-4)16-25(46-5)30(31)34/h6,9-10,15-20H,1,7-8,11-14H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443228 (N-(5-(4-(Cyclopropyl(methyl)amino)piperidin-1-yl)-...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-28(43)38-23-15-21(42-13-11-20(12-14-42)40(2)19-7-8-19)9-10-22(23)37-26-17-27(36-18-35-26)41(3)32(44)39-31-29(33)24(45-4)16-25(46-5)30(31)34/h6,9-10,15-20H,1,7-8,11-14H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443228 (N-(5-(4-(Cyclopropyl(methyl)amino)piperidin-1-yl)-...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-28(43)38-23-15-21(42-13-11-20(12-14-42)40(2)19-7-8-19)9-10-22(23)37-26-17-27(36-18-35-26)41(3)32(44)39-31-29(33)24(45-4)16-25(46-5)30(31)34/h6,9-10,15-20H,1,7-8,11-14H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	311	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443225 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CCN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)C1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-13-11-32(18-42)10-12-41(7-2)17-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443223 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)CC1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-17-32(18-42)10-12-41(7-2)13-11-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	382	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443226 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C)ncn2)c1Cl Show InChI InChI=1S/C30H36Cl2N8O4/c1-7-26(41)36-21-14-19(40-12-10-18(11-13-40)38(2)3)8-9-20(21)35-24-16-25(34-17-33-24)39(4)30(42)37-29-27(31)22(43-5)15-23(44-6)28(29)32/h7-9,14-18H,1,10-13H2,2-6H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443223 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)CC1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-17-32(18-42)10-12-41(7-2)13-11-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	439	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443222 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C31H36Cl2N8O4/c1-5-26(42)38-21-14-19(41-13-10-31(17-41)8-11-34-12-9-31)6-7-20(21)37-24-16-25(36-18-35-24)40(2)30(43)39-29-27(32)22(44-3)15-23(45-4)28(29)33/h5-7,14-16,18,34H,1,8-13,17H2,2-4H3,(H,38,42)(H,39,43)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	465	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443224 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCN(CC11CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C31H36Cl2N8O4/c1-6-26(42)37-21-14-19(40-12-13-41(7-2)31(17-40)10-11-31)8-9-20(21)36-24-16-25(35-18-34-24)39(3)30(43)38-29-27(32)22(44-4)15-23(45-5)28(29)33/h6,8-9,14-16,18H,1,7,10-13,17H2,2-5H3,(H,37,42)(H,38,43)(H,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	533	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443225 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CCN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)C1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-13-11-32(18-42)10-12-41(7-2)17-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	544	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443220 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-25(41)37-20-12-18(40-15-30(16-40)8-10-33-11-9-30)6-7-19(20)36-23-14-24(35-17-34-23)39(2)29(42)38-28-26(31)21(43-3)13-22(44-4)27(28)32/h5-7,12-14,17,33H,1,8-11,15-16H2,2-4H3,(H,37,41)(H,38,42)(H,34,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	557	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM249396 (US10537571, Compound 108 | US10562888, Compound 10...) Show SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM249396 (US10537571, Compound 108 | US10562888, Compound 10...) Show SMILES CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34-23-16-24(33-17-32-23)37(3)29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	579	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443227 (N-(5-(4-Cyclopropylpiperazin-1-yl)-2-((6-(3-(2,6-d...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCN(CC3)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-26(41)36-21-14-19(40-12-10-39(11-13-40)18-6-7-18)8-9-20(21)35-24-16-25(34-17-33-24)38(2)30(42)37-29-27(31)22(43-3)15-23(44-4)28(29)32/h5,8-9,14-18H,1,6-7,10-13H2,2-4H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	618	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM443224 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCN(CC11CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C31H36Cl2N8O4/c1-6-26(42)37-21-14-19(40-12-13-41(7-2)31(17-40)10-11-31)8-9-20(21)36-24-16-25(35-18-34-24)39(3)30(43)38-29-27(32)22(44-4)15-23(45-5)28(29)33/h6,8-9,14-16,18H,1,7,10-13,17H2,2-5H3,(H,37,42)(H,38,43)(H,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	624	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443227 (N-(5-(4-Cyclopropylpiperazin-1-yl)-2-((6-(3-(2,6-d...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCN(CC3)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-26(41)36-21-14-19(40-12-10-39(11-13-40)18-6-7-18)8-9-20(21)35-24-16-25(34-17-33-24)38(2)30(42)37-29-27(31)22(43-3)15-23(44-4)28(29)32/h5,8-9,14-18H,1,6-7,10-13H2,2-4H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	644	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443222 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C31H36Cl2N8O4/c1-5-26(42)38-21-14-19(41-13-10-31(17-41)8-11-34-12-9-31)6-7-20(21)37-24-16-25(36-18-35-24)40(2)30(43)39-29-27(32)22(44-3)15-23(45-4)28(29)33/h5-7,14-16,18,34H,1,8-13,17H2,2-4H3,(H,38,42)(H,39,43)(H,35,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443226 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC(CC3)N(C)C)ncn2)c1Cl Show InChI InChI=1S/C30H36Cl2N8O4/c1-7-26(41)36-21-14-19(40-12-10-18(11-13-40)38(2)3)8-9-20(21)35-24-16-25(34-17-33-24)39(4)30(42)37-29-27(31)22(43-5)15-23(44-6)28(29)32/h7-9,14-18H,1,10-13H2,2-6H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	729	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443225 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCC2(CCN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)C1 Show InChI InChI=1S/C32H38Cl2N8O4/c1-6-27(43)38-22-14-20(42-13-11-32(18-42)10-12-41(7-2)17-32)8-9-21(22)37-25-16-26(36-19-35-25)40(3)31(44)39-30-28(33)23(45-4)15-24(46-5)29(30)34/h6,8-9,14-16,19H,1,7,10-13,17-18H2,2-5H3,(H,38,43)(H,39,44)(H,35,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	731	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443220 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-25(41)37-20-12-18(40-15-30(16-40)8-10-33-11-9-30)6-7-19(20)36-23-14-24(35-17-34-23)39(2)29(42)38-28-26(31)21(43-3)13-22(44-4)27(28)32/h5-7,12-14,17,33H,1,8-11,15-16H2,2-4H3,(H,37,41)(H,38,42)(H,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	777	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443227 (N-(5-(4-Cyclopropylpiperazin-1-yl)-2-((6-(3-(2,6-d...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCN(CC3)C3CC3)ncn2)c1Cl Show InChI InChI=1S/C30H34Cl2N8O4/c1-5-26(41)36-21-14-19(40-12-10-39(11-13-40)18-6-7-18)8-9-20(21)35-24-16-25(34-17-33-24)38(2)30(42)37-29-27(31)22(43-3)15-23(44-4)28(29)32/h5,8-9,14-18H,1,6-7,10-13H2,2-4H3,(H,36,41)(H,37,42)(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM443224 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES CCN1CCN(CC11CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1 Show InChI InChI=1S/C31H36Cl2N8O4/c1-6-26(42)37-21-14-19(40-12-13-41(7-2)31(17-40)10-11-31)8-9-20(21)36-24-16-25(35-18-34-24)39(3)30(43)38-29-27(32)22(44-4)15-23(45-5)28(29)33/h6,8-9,14-16,18H,1,7,10-13,17H2,2-5H3,(H,37,42)(H,38,43)(H,34,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	989	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM443222 (N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-m...) Show SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCC4(C3)CCNCC4)ncn2)c1Cl Show InChI InChI=1S/C31H36Cl2N8O4/c1-5-26(42)38-21-14-19(41-13-10-31(17-41)8-11-34-12-9-31)6-7-20(21)37-24-16-25(36-18-35-24)40(2)30(43)39-29-27(32)22(44-3)15-23(45-4)28(29)33/h5-7,14-16,18,34H,1,8-13,17H2,2-4H3,(H,38,42)(H,39,43)(H,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...				US Patent US10654836 (2020) BindingDB Entry DOI: 10.7270/Q25M68RT
					More data for this Ligand-Target Pair