Compile Data Set for Download or QSAR

Found 78 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316107 (US9616064, Compound 30g | US9616064, Compound 30h) Show SMILES CC(NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1)c1ccccc1 Show InChI InChI=1S/C21H19N5O/c1-14(15-6-3-2-4-7-15)24-20(27)17-8-5-9-18-16(17)11-13-26(18)19-10-12-23-21(22)25-19/h2-14H,1H3,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316103 (US9616064, Compound 30b) Show SMILES COc1cccc(CNC(=O)c2cccc3n(ccc23)-c2ccnc(N)n2)c1 Show InChI InChI=1S/C21H19N5O2/c1-28-15-5-2-4-14(12-15)13-24-20(27)17-6-3-7-18-16(17)9-11-26(18)19-8-10-23-21(22)25-19/h2-12H,13H2,1H3,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316125 (US9616064, Compound 30w) Show SMILES COc1cccc(c1)[C@@H](C)NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1 |r| Show InChI InChI=1S/C22H21N5O2/c1-14(15-5-3-6-16(13-15)29-2)25-21(28)18-7-4-8-19-17(18)10-12-27(19)20-9-11-24-22(23)26-20/h3-14H,1-2H3,(H,25,28)(H2,23,24,26)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316088 (US9616064, Compound 15f) Show SMILES COc1ccc2n(ccc2c1)-c1ccnc(N)n1 Show InChI InChI=1S/C13H12N4O/c1-18-10-2-3-11-9(8-10)5-7-17(11)12-4-6-15-13(14)16-12/h2-8H,1H3,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316081 (US9616064, Compound 13o) Show SMILES CC1Cc2cc(F)ccc2N1c1ccnc(N)n1 Show InChI InChI=1S/C13H13FN4/c1-8-6-9-7-10(14)2-3-11(9)18(8)12-4-5-16-13(15)17-12/h2-5,7-8H,6H2,1H3,(H2,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316097 (US9616064, Compound 13q) Show SMILES Nc1nccc(n1)N1CCc2c1cccc2OCc1ccccc1 Show InChI InChI=1S/C19H18N4O/c20-19-21-11-9-18(22-19)23-12-10-15-16(23)7-4-8-17(15)24-13-14-5-2-1-3-6-14/h1-9,11H,10,12-13H2,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316076 (US9616064, Compound 13i) Show SMILES CC1Cc2cc(ccc2N1c1ccnc(N)n1)[N+]([O-])=O Show InChI InChI=1S/C13H13N5O2/c1-8-6-9-7-10(18(19)20)2-3-11(9)17(8)12-4-5-15-13(14)16-12/h2-5,7-8H,6H2,1H3,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316087 (US9616064, Compound 21a) Show SMILES Nc1nccc(n1)-n1ccc2c(OCc3ccccc3)cccc12 Show InChI InChI=1S/C19H16N4O/c20-19-21-11-9-18(22-19)23-12-10-15-16(23)7-4-8-17(15)24-13-14-5-2-1-3-6-14/h1-12H,13H2,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316091 (US9616064, Compound 24b) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C20H17N5O/c21-20-22-11-9-18(24-20)25-12-10-15-16(7-4-8-17(15)25)19(26)23-13-14-5-2-1-3-6-14/h1-12H,13H2,(H,23,26)(H2,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316074 (US9616064, Compound 13f) Show SMILES Nc1nccc(n1)N1CCc2cc(F)ccc12 Show InChI InChI=1S/C12H11FN4/c13-9-1-2-10-8(7-9)4-6-17(10)11-3-5-15-12(14)16-11/h1-3,5,7H,4,6H2,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316079 (US9616064, Compound 13m) Show SMILES CC1Cc2cc(Cl)ccc2N1c1ccnc(N)n1 Show InChI InChI=1S/C13H13ClN4/c1-8-6-9-7-10(14)2-3-11(9)18(8)12-4-5-16-13(15)17-12/h2-5,7-8H,6H2,1H3,(H2,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50429636 (CHEMBL2334964 | US9616064, Compound 15d) Show SMILES Nc1nccc(n1)-n1ccc2ccc(Cl)cc12 Show InChI InChI=1S/C12H9ClN4/c13-9-2-1-8-4-6-17(10(8)7-9)11-3-5-15-12(14)16-11/h1-7H,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316126 (US9616064, Compound 30z) Show SMILES COc1cccc(c1)[C@H](C)NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1 |r| Show InChI InChI=1S/C22H21N5O2/c1-14(15-5-3-6-16(13-15)29-2)25-21(28)18-7-4-8-19-17(18)10-12-27(19)20-9-11-24-22(23)26-20/h3-14H,1-2H3,(H,25,28)(H2,23,24,26)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316114 (US9616064, Compound 30n) Show SMILES CC(=O)Nc1cccc(CNC(=O)c2cccc3n(ccc23)-c2ccnc(N)n2)c1 |$;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C22H20N6O2/c1-14(29)26-16-5-2-4-15(12-16)13-25-21(30)18-6-3-7-19-17(18)9-11-28(19)20-8-10-24-22(23)27-20/h2-12H,13H2,1H3,(H,25,30)(H,26,29)(H2,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316070 (US9616064, Compound 13c) Show SMILES Nc1nccc(n1)N1CCc2cc(Cl)ccc12 Show InChI InChI=1S/C12H11ClN4/c13-9-1-2-10-8(7-9)4-6-17(10)11-3-5-15-12(14)16-11/h1-3,5,7H,4,6H2,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316128 (US9616064, Compound 13r) Show SMILES COc1cccc(CNC(=O)c2cccc3N(CCc23)c2ccnc(N)n2)c1 Show InChI InChI=1S/C21H21N5O2/c1-28-15-5-2-4-14(12-15)13-24-20(27)17-6-3-7-18-16(17)9-11-26(18)19-8-10-23-21(22)25-19/h2-8,10,12H,9,11,13H2,1H3,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316107 (US9616064, Compound 30g | US9616064, Compound 30h) Show SMILES CC(NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1)c1ccccc1 Show InChI InChI=1S/C21H19N5O/c1-14(15-6-3-2-4-7-15)24-20(27)17-8-5-9-18-16(17)11-13-26(18)19-10-12-23-21(22)25-19/h2-14H,1H3,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316065 (US9616064, Compound 13b) Show SMILES CC1Cc2ccccc2N1c1ccnc(N)n1 Show InChI InChI=1S/C13H14N4/c1-9-8-10-4-2-3-5-11(10)17(9)12-6-7-15-13(14)16-12/h2-7,9H,8H2,1H3,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316077 (US9616064, Compound 13j) Show SMILES Nc1nccc(n1)N1CCc2cc(Br)ccc12 Show InChI InChI=1S/C12H11BrN4/c13-9-1-2-10-8(7-9)4-6-17(10)11-3-5-15-12(14)16-11/h1-3,5,7H,4,6H2,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316115 (US9616064, Compound 30o) Show SMILES CC[C@@H](NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1)c1ccccc1 |r| Show InChI InChI=1S/C22H21N5O/c1-2-18(15-7-4-3-5-8-15)25-21(28)17-9-6-10-19-16(17)12-14-27(19)20-11-13-24-22(23)26-20/h3-14,18H,2H2,1H3,(H,25,28)(H2,23,24,26)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316100 (US9616064, Compound 21e) Show SMILES Nc1nccc(n1)-n1ccc2c(OCc3ccc(Cl)cc3)cccc12 Show InChI InChI=1S/C19H15ClN4O/c20-14-6-4-13(5-7-14)12-25-17-3-1-2-16-15(17)9-11-24(16)18-8-10-22-19(21)23-18/h1-11H,12H2,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316092 (US9616064, Compound 24c) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C21H19N5O/c22-21-24-13-10-19(25-21)26-14-11-16-17(7-4-8-18(16)26)20(27)23-12-9-15-5-2-1-3-6-15/h1-8,10-11,13-14H,9,12H2,(H,23,27)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316084 (US9616064, Compound 15c) Show SMILES Nc1nccc(n1)-n1ccc2cc(Br)ccc12 Show InChI InChI=1S/C12H9BrN4/c13-9-1-2-10-8(7-9)4-6-17(10)11-3-5-15-12(14)16-11/h1-7H,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316073 (US9616064, Compound 13d) Show SMILES Nc1nccc(n1)N1CCc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C12H11N5O2/c13-12-14-5-3-11(15-12)16-6-4-8-1-2-9(17(18)19)7-10(8)16/h1-3,5,7H,4,6H2,(H2,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316096 (US9616064, Compound 27e) Show SMILES Nc1nccc(n1)-n1ccc2cc(ccc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C20H17N5O/c21-20-22-10-8-18(24-20)25-11-9-15-12-16(6-7-17(15)25)19(26)23-13-14-4-2-1-3-5-14/h1-12H,13H2,(H,23,26)(H2,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316105 (US9616064, Compound 30d) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1cccc(F)c1 Show InChI InChI=1S/C20H16FN5O/c21-14-4-1-3-13(11-14)12-24-19(27)16-5-2-6-17-15(16)8-10-26(17)18-7-9-23-20(22)25-18/h1-11H,12H2,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316095 (US9616064, Compound 27d) Show SMILES Nc1nccc(n1)-n1ccc2cc(ccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C21H19N5O/c22-21-24-12-9-19(25-21)26-13-10-16-14-17(6-7-18(16)26)20(27)23-11-8-15-4-2-1-3-5-15/h1-7,9-10,12-14H,8,11H2,(H,23,27)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316113 (US9616064, Compound 30m) Show SMILES CS(=O)(=O)Nc1cccc(CNC(=O)c2cccc3n(ccc23)-c2ccnc(N)n2)c1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C21H20N6O3S/c1-31(29,30)26-15-5-2-4-14(12-15)13-24-20(28)17-6-3-7-18-16(17)9-11-27(18)19-8-10-23-21(22)25-19/h2-12,26H,13H2,1H3,(H,24,28)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316120 (US9616064, Compound 3s) Show SMILES CCOc1cccc(CNC(=O)c2cccc3n(ccc23)-c2ccnc(N)n2)c1 Show InChI InChI=1S/C22H21N5O2/c1-2-29-16-6-3-5-15(13-16)14-25-21(28)18-7-4-8-19-17(18)10-12-27(19)20-9-11-24-22(23)26-20/h3-13H,2,14H2,1H3,(H,25,28)(H2,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316110 (US9616064, Compound 30j) Show SMILES C[C@H](NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1)c1ccccc1 |r| Show InChI InChI=1S/C21H19N5O/c1-14(15-6-3-2-4-7-15)24-20(27)17-8-5-9-18-16(17)11-13-26(18)19-10-12-23-21(22)25-19/h2-14H,1H3,(H,24,27)(H2,22,23,25)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316082 (US9616064, Compound 13p) Show SMILES Nc1nccc(n1)N1CCc2ccc(F)cc12 Show InChI InChI=1S/C12H11FN4/c13-9-2-1-8-4-6-17(10(8)7-9)11-3-5-15-12(14)16-11/h1-3,5,7H,4,6H2,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316066 (US9616064, Compound 1bb) Show SMILES Nc1nccc(Nc2ccc(cc2)[N+]([O-])=O)n1 Show InChI InChI=1S/C10H9N5O2/c11-10-12-6-5-9(14-10)13-7-1-3-8(4-2-7)15(16)17/h1-6H,(H3,11,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50432338 (CHEMBL2348176 | US9616064, Compound 15a) Show SMILES Nc1nccc(n1)-n1ccc2ccccc12 Show InChI InChI=1S/C12H10N4/c13-12-14-7-5-11(15-12)16-8-6-9-3-1-2-4-10(9)16/h1-8H,(H2,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316078 (US9616064, Compound 13l) Show SMILES CC1CN(c2ccccc12)c1ccnc(N)n1 Show InChI InChI=1S/C13H14N4/c1-9-8-17(11-5-3-2-4-10(9)11)12-6-7-15-13(14)16-12/h2-7,9H,8H2,1H3,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316067 (US9616064, Compound 6) Show SMILES Nc1nccc(Nc2cccc(c2)[N+]([O-])=O)n1 Show InChI InChI=1S/C10H9N5O2/c11-10-12-5-4-9(14-10)13-7-2-1-3-8(6-7)15(16)17/h1-6H,(H3,11,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316090 (US9616064, Compound 15h) Show SMILES COc1ccc2n(cc(CCNC(C)=O)c2c1)-c1ccnc(N)n1 Show InChI InChI=1S/C17H19N5O2/c1-11(23)19-7-5-12-10-22(16-6-8-20-17(18)21-16)15-4-3-13(24-2)9-14(12)15/h3-4,6,8-10H,5,7H2,1-2H3,(H,19,23)(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50432360 (CHEMBL2348175 | US9616064, Compound 15b) Show SMILES Nc1nccc(n1)-n1ccc2ccc(F)cc12 Show InChI InChI=1S/C12H9FN4/c13-9-2-1-8-4-6-17(10(8)7-9)11-3-5-15-12(14)16-11/h1-7H,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316086 (US9616064, Compound 15e) Show SMILES COc1ccc2ccn(-c3ccnc(N)n3)c2c1 Show InChI InChI=1S/C13H12N4O/c1-18-10-3-2-9-5-7-17(11(9)8-10)12-4-6-15-13(14)16-12/h2-8H,1H3,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316111 (US9616064, Compound 30k) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1ccccc1F Show InChI InChI=1S/C20H16FN5O/c21-16-6-2-1-4-13(16)12-24-19(27)15-5-3-7-17-14(15)9-11-26(17)18-8-10-23-20(22)25-18/h1-11H,12H2,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316127 (US9616064, Compound 1bj) Show SMILES Nc1nccc(Nc2cccc(Cl)c2)n1 |$;;;;;;HN;;;;;;;;$| Show InChI InChI=1S/C10H9ClN4/c11-7-2-1-3-8(6-7)14-9-4-5-13-10(12)15-9/h1-6H,(H3,12,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316109 (US9616064, Compound 30i) Show SMILES COc1ccccc1CNC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1 Show InChI InChI=1S/C21H19N5O2/c1-28-18-8-3-2-5-14(18)13-24-20(27)16-6-4-7-17-15(16)10-12-26(17)19-9-11-23-21(22)25-19/h2-12H,13H2,1H3,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM314082 (US9616064, Compound 1ag) Show SMILES Nc1nccc(Nc2cccc(c2)S(N)(=O)=O)n1 Show InChI InChI=1S/C10H11N5O2S/c11-10-13-5-4-9(15-10)14-7-2-1-3-8(6-7)18(12,16)17/h1-6H,(H2,12,16,17)(H3,11,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316060 (US9616064, Compound 13a) Show SMILES Nc1nccc(n1)N1CCc2ccccc12 Show InChI InChI=1S/C12H12N4/c13-12-14-7-5-11(15-12)16-8-6-9-3-1-2-4-10(9)16/h1-5,7H,6,8H2,(H2,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316059 (US9616064, Compound 1an) Show SMILES CS(=O)(=O)c1cccc(Nc2ccnc(N)n2)c1 Show InChI InChI=1S/C11H12N4O2S/c1-18(16,17)9-4-2-3-8(7-9)14-10-5-6-13-11(12)15-10/h2-7H,1H3,(H3,12,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316104 (US9616064, Compound 30c) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C20H16ClN5O/c21-14-4-1-3-13(11-14)12-24-19(27)16-5-2-6-17-15(16)8-10-26(17)18-7-9-23-20(22)25-18/h1-11H,12H2,(H,24,27)(H2,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316123 (US9616064, Compound 46) Show SMILES COc1cccc(CNC(=O)c2cccc(Nc3ccnc(N)n3)c2)c1 |$;;;;;;;;;;;;;;;;HN;;;;;;;;;$| Show InChI InChI=1S/C19H19N5O2/c1-26-16-7-2-4-13(10-16)12-22-18(25)14-5-3-6-15(11-14)23-17-8-9-21-19(20)24-17/h2-11H,12H2,1H3,(H,22,25)(H3,20,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316089 (US9616064, Compound 15g) Show SMILES Cc1ccc2n(ccc2c1)-c1ccnc(N)n1 Show InChI InChI=1S/C13H12N4/c1-9-2-3-11-10(8-9)5-7-17(11)12-4-6-15-13(14)16-12/h2-8H,1H3,(H2,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316122 (US9616064, Compound 30v) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCc1cccc(c1)N1CCCC1=O Show InChI InChI=1S/C24H22N6O2/c25-24-26-11-9-21(28-24)30-13-10-18-19(6-2-7-20(18)30)23(32)27-15-16-4-1-5-17(14-16)29-12-3-8-22(29)31/h1-2,4-7,9-11,13-14H,3,8,12,15H2,(H,27,32)(H2,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316119 (US9616064, Compound 30r) Show SMILES COCCOc1cccc(CNC(=O)c2cccc3n(ccc23)-c2ccnc(N)n2)c1 Show InChI InChI=1S/C23H23N5O3/c1-30-12-13-31-17-5-2-4-16(14-17)15-26-22(29)19-6-3-7-20-18(19)9-11-28(20)21-8-10-25-23(24)27-21/h2-11,14H,12-13,15H2,1H3,(H,26,29)(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316129 (US9616064, Compound 30aa) Show SMILES CC[C@H](NC(=O)c1cccc2n(ccc12)-c1ccnc(N)n1)c1ccccc1 |r| Show InChI InChI=1S/C22H21N5O/c1-2-18(15-7-4-3-5-8-15)25-21(28)17-9-6-10-19-16(17)12-14-27(19)20-11-13-24-22(23)26-20/h3-14,18H,2H2,1H3,(H,25,28)(H2,23,24,26)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair

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