Found 13 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50019920 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM35440
(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)Show InChI InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10) | PDB MMDB
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PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208873
(2-chloro-6(methylamino)purine | CHEMBL446449)Show InChI InChI=1S/C6H6ClN5/c1-8-4-3-5(10-2-9-3)12-6(7)11-4/h2H,1H3,(H2,8,9,10,11,12) | PDB MMDB
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Patents
Similars
| Article PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM33218
(Adenine, 1 | CHEMBL226345 | purine, 6)Show InChI InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10) | PDB MMDB
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Patents
Similars
| Article PubMed
| n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208876
(1H-Pyrazolo[3,4-d]pyrimidin-4-ylamine | 4-aminopyr...)Show InChI InChI=1S/C5H5N5/c6-4-3-1-9-10-5(3)8-2-7-4/h1-2H,(H3,6,7,8,9,10) | PDB MMDB
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Patents
Similars
| Article PubMed
| n/a | n/a | 3.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208881
(5-Nitro-1H-benzoimidazole | 5-nitrobenzimidazole |...)Show InChI InChI=1S/C7H5N3O2/c11-10(12)5-1-2-6-7(3-5)9-4-8-6/h1-4H,(H,8,9) | PDB MMDB
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CHEMBL MCE MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50200099
(2-Amino-1,7-dihydro-purine-6-thione | 2-Amino-1,9-...)Show InChI InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11) | PDB MMDB
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CHEMBL MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 9.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM82020
(1-Methyl-3,9-dihydro-purine-2,6-dione(1-methyl xan...)Show InChI InChI=1S/C6H4N4O2/c1-10-5(11)3-4(8-2-7-3)9-6(10)12/h2H,1H3 | PDB MMDB
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CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208879
(2,6-diaminopurine | 9H-Purine-2,6-diamine0.5M H2SO...)Show InChI InChI=1S/C5H6N6/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H5,6,7,8,9,10,11) | PDB MMDB
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CHEMBL MCE MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208880
(5-methyl-1H-benzimidazole | CHEMBL157729)Show InChI InChI=1S/C8H8N2/c1-6-2-3-7-8(4-6)10-5-9-7/h2-5H,1H3,(H,9,10) | PDB MMDB
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CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208877
(2-amino-6-chloropurine | 6-Cl-purine (1) | 6-chlor...)Show InChI InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208875
(2-aminopurine | 9H-Purin-2-ylamine | 9H-purin-2-am...)Show InChI InChI=1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10) | PDB MMDB
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM50208872
(5,6-dimethyl-1H-benzimidazole | 5,6-dimethylbenzim...)Show InChI InChI=1S/C9H10N2/c1-6-3-8-9(4-7(6)2)11-5-10-8/h3-5H,1-2H3,(H,10,11) | PDB MMDB
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human)) | BDBM5470
(6-methoxy-9H-purin-2-amine | CHEMBL226395 | O6-Sub...)Show InChI InChI=1S/C6H7N5O/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Biological Chemistry and the Genomics Research Center
Curated by ChEMBL
| Assay Description Inhibition of human xanthine oxidase |
Bioorg Med Chem 15: 3450-6 (2007)
Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G |
More data for this Ligand-Target Pair | |