Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287432 ((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287440 ((S)-2-[(1-{[(R)-1-((S)-6-Benzyloxycarbonylamino-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287430 ((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287438 ((S)-2-[(1-{[(R)-1-(4-Aminomethyl-benzoylamino)-2-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287431 ((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287437 ((S)-2-[(1-{Hydroxy-[(R)-1-(4-methoxy-benzoylamino)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287444 ((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287434 ((S)-2-({1-[((R)-1-Benzoylamino-2-phenyl-ethyl)-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287445 ((S)-2-({1-[(Benzyloxycarbonylamino-methyl)-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50251742 ((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287442 ((S)-2-[(1-{[(R)-1-(2,2-Dimethyl-propionylamino)-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287439 ((S)-2-({1-[((R)-1-Acetylamino-2-phenyl-ethyl)-hydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287443 ((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287436 ((S)-3-(1H-Indol-3-yl)-2-((S)-4-methyl-2-phosphonoa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50085452 ((S)-2-[((S)-6-Amino-2-methanesulfonylamino-hexanoy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287433 ((S)-2-[(1-{[(S)-1-((S)-6-Amino-2-methanesulfonylam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287435 ((S)-2-[(1-{[(S)-1-((S)-6-Benzyloxycarbonylamino-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50287441 ((S)-2-({1-[((S)-1-Benzyloxycarbonylamino-2-phenyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l... | Bioorg Med Chem Lett 6: 1629-1634 (1996) Article DOI: 10.1016/0960-894X(96)00297-1 BindingDB Entry DOI: 10.7270/Q2697437 | |||||||||||
More data for this Ligand-Target Pair |