new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50036167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM21393
PNG
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3
KEGG

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
0.630n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in membrane homogenates of hippocampal tissue of rat br...


J Med Chem 36: 3161-5 (1993)


BindingDB Entry DOI: 10.7270/Q2JQ11N4
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50041469
PNG
((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Show SMILES CCCN(C\C=C\I)C1CCc2cccc(O)c2C1
Show InChI InChI=1S/C16H22INO/c1-2-10-18(11-4-9-17)14-8-7-13-5-3-6-16(19)15(13)12-14/h3-6,9,14,19H,2,7-8,10-12H2,1H3/b9-4+
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
0.920n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in membrane homogenates of hippocampal tissue of rat br...


J Med Chem 36: 3161-5 (1993)


BindingDB Entry DOI: 10.7270/Q2JQ11N4
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50041951
PNG
((R,S) 7-(3-Iodo-allylamino)-5,6,7,8-tetrahydro-nap...)
Show SMILES Oc1cccc2CCC(Cc12)NC\C=C\I
Show InChI InChI=1S/C13H16INO/c14-7-2-8-15-11-6-5-10-3-1-4-13(16)12(10)9-11/h1-4,7,11,15-16H,5-6,8-9H2/b7-2+
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
10n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in membrane homogenates of hippocampal tissue of rat br...


J Med Chem 36: 3161-5 (1993)


BindingDB Entry DOI: 10.7270/Q2JQ11N4
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50041952
PNG
((R,S) (3-Iodo-allyl)-(8-methoxy-1,2,3,4-tetrahydro...)
Show SMILES CCCN(C\C=C\I)C1CCc2cccc(OC)c2C1
Show InChI InChI=1S/C17H24INO/c1-3-11-19(12-5-10-18)15-9-8-14-6-4-7-17(20-2)16(14)13-15/h4-7,10,15H,3,8-9,11-13H2,1-2H3/b10-5+
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
13n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in membrane homogenates of hippocampal tissue of rat br...


J Med Chem 36: 3161-5 (1993)


BindingDB Entry DOI: 10.7270/Q2JQ11N4
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50041953
PNG
((R,S) (3-Iodo-allyl)-(8-methoxy-1,2,3,4-tetrahydro...)
Show SMILES COc1cccc2CCC(Cc12)NC\C=C\I
Show InChI InChI=1S/C14H18INO/c1-17-14-5-2-4-11-6-7-12(10-13(11)14)16-9-3-8-15/h2-5,8,12,16H,6-7,9-10H2,1H3/b8-3+
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
17n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in membrane homogenates of hippocampal tissue of rat br...


J Med Chem 36: 3161-5 (1993)


BindingDB Entry DOI: 10.7270/Q2JQ11N4
More data for this
Ligand-Target Pair