Found 19 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50044676 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50078125
((1-Amino-3-phenyl-propyl)-phosphinic acid | CHEMBL...)Show InChI InChI=1S/C9H12NO2P/c10-9(13(11)12)7-6-8-4-2-1-3-5-8/h1-5,10-12H,6-7H2 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025070
(CHEMBL3355110)Show SMILES NCc1ccc(CC(CP(O)(=O)C(N)CCc2cccnc2)C(O)=O)cc1 Show InChI InChI=1S/C19H26N3O4P/c20-11-15-5-3-14(4-6-15)10-17(19(23)24)13-27(25,26)18(21)8-7-16-2-1-9-22-12-16/h1-6,9,12,17-18H,7-8,10-11,13,20-21H2,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025048
(CHEMBL3355099)Show InChI InChI=1S/C9H14NO3P/c10-9(14(11,12)13)7-6-8-4-2-1-3-5-8/h1-5,9H,6-7,10H2,(H2,11,12,13)/t9-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025066
(CHEMBL3355109)Show SMILES NCc1ccc(CC(CP(O)(=O)C(N)CCc2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C20H27N2O4P/c21-13-17-8-6-16(7-9-17)12-18(20(23)24)14-27(25,26)19(22)11-10-15-4-2-1-3-5-15/h1-9,18-19H,10-14,21-22H2,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50316049
(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)Show InChI InChI=1S/C9H14NO3P/c10-9(14(11,12)13)7-6-8-4-2-1-3-5-8/h1-5,9H,6-7,10H2,(H2,11,12,13) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025099
(CHEMBL3355111)Show SMILES NCc1cccc(CC(CP(O)(=O)C(N)CCc2ccncc2)C(O)=O)c1 Show InChI InChI=1S/C19H26N3O4P/c20-12-16-3-1-2-15(10-16)11-17(19(23)24)13-27(25,26)18(21)5-4-14-6-8-22-9-7-14/h1-3,6-10,17-18H,4-5,11-13,20-21H2,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025041
(CHEMBL3355106)Show InChI InChI=1S/C18H23N2O4P/c19-17(7-6-14-8-10-20-11-9-14)25(23,24)13-16(18(21)22)12-15-4-2-1-3-5-15/h1-5,8-11,16-17H,6-7,12-13,19H2,(H,21,22)(H,23,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025043
(CHEMBL3355104)Show SMILES NC(CCc1ccc(CO)cc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H26NO5P/c21-19(11-10-15-6-8-17(13-22)9-7-15)27(25,26)14-18(20(23)24)12-16-4-2-1-3-5-16/h1-9,18-19,22H,10-14,21H2,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50129684
(3-[(1-amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...)Show InChI InChI=1S/C19H24NO4P/c20-18(12-11-15-7-3-1-4-8-15)25(23,24)14-17(19(21)22)13-16-9-5-2-6-10-16/h1-10,17,20,23-25H,11-14H2,(H,21,22) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025050
(CHEMBL3355108)Show SMILES NCc1cccc(CC(CP(O)(=O)C(N)CCc2ccccc2)C(O)=O)c1 Show InChI InChI=1S/C20H27N2O4P/c21-13-17-8-4-7-16(11-17)12-18(20(23)24)14-27(25,26)19(22)10-9-15-5-2-1-3-6-15/h1-8,11,18-19H,9-10,12-14,21-22H2,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025042
(CHEMBL3355105)Show InChI InChI=1S/C18H23N2O4P/c19-17(9-8-15-7-4-10-20-12-15)25(23,24)13-16(18(21)22)11-14-5-2-1-3-6-14/h1-7,10,12,16-17H,8-9,11,13,19H2,(H,21,22)(H,23,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025046
(CHEMBL3355101)Show SMILES NC(CCc1ccc(cc1)[N+]([O-])=O)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C19H23N2O6P/c20-18(11-8-14-6-9-17(10-7-14)21(24)25)28(26,27)13-16(19(22)23)12-15-4-2-1-3-5-15/h1-7,9-10,16,18H,8,11-13,20H2,(H,22,23)(H,26,27) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50024594
((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025047
(CHEMBL3355100)Show SMILES Cc1cc(C)cc(CCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)c1 Show InChI InChI=1S/C21H28NO4P/c1-15-10-16(2)12-18(11-15)8-9-20(22)27(25,26)14-19(21(23)24)13-17-6-4-3-5-7-17/h3-7,10-12,19-20H,8-9,13-14,22H2,1-2H3,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50129681
(3-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...)Show SMILES OC(=O)C(Cc1ccc(O)cc1)CP(O)(O)C(=N)CCc1ccccc1 Show InChI InChI=1S/C19H24NO5P/c20-18(11-8-14-4-2-1-3-5-14)26(24,25)13-16(19(22)23)12-15-6-9-17(21)10-7-15/h1-7,9-10,16,20-21,24-26H,8,11-13H2,(H,22,23) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025044
(CHEMBL3355103)Show SMILES NC(CCc1ccc(O)cc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C19H24NO5P/c20-18(11-8-14-6-9-17(21)10-7-14)26(24,25)13-16(19(22)23)12-15-4-2-1-3-5-15/h1-7,9-10,16,18,21H,8,11-13,20H2,(H,22,23)(H,24,25) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025049
(CHEMBL3355107)Show SMILES Cc1cc(C)cc(CC(CP(O)(=O)C(N)CCc2ccccc2)C(O)=O)c1 Show InChI InChI=1S/C21H28NO4P/c1-15-10-16(2)12-18(11-15)13-19(21(23)24)14-27(25,26)20(22)9-8-17-6-4-3-5-7-17/h3-7,10-12,19-20H,8-9,13-14,22H2,1-2H3,(H,23,24)(H,25,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50025045
(CHEMBL3355102)Show SMILES NC(CCc1cccc(O)c1)P(O)(=O)CC(Cc1ccccc1)C(O)=O Show InChI InChI=1S/C19H24NO5P/c20-18(10-9-15-7-4-8-17(21)12-15)26(24,25)13-16(19(22)23)11-14-5-2-1-3-6-14/h1-8,12,16,18,21H,9-11,13,20H2,(H,22,23)(H,24,25) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 146 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50024597
((S)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Athens
Curated by ChEMBL
| Assay Description Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation |
J Med Chem 57: 8140-51 (2014)
Article DOI: 10.1021/jm501071f BindingDB Entry DOI: 10.7270/Q2CF9RQF |
More data for this Ligand-Target Pair | |